PL366630A1 - Selektywne cykliczne peptydy - Google Patents

Selektywne cykliczne peptydy

Info

Publication number
PL366630A1
PL366630A1 PL01366630A PL36663001A PL366630A1 PL 366630 A1 PL366630 A1 PL 366630A1 PL 01366630 A PL01366630 A PL 01366630A PL 36663001 A PL36663001 A PL 36663001A PL 366630 A1 PL366630 A1 PL 366630A1
Authority
PL
Poland
Prior art keywords
cyclic peptides
selective cyclic
selective
peptides
cyclic
Prior art date
Application number
PL01366630A
Other languages
English (en)
Inventor
Li Chen
Adrian Wai-Hing Cheung
Xin-Jie Chu
Waleed Danho
Joseph Swistok
Yao Wang
Keith Alan Yagaloff
Original Assignee
F.Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag
Publication of PL366630A1 publication Critical patent/PL366630A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL01366630A 2000-08-30 2001-08-21 Selektywne cykliczne peptydy PL366630A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22918400P 2000-08-30 2000-08-30

Publications (1)

Publication Number Publication Date
PL366630A1 true PL366630A1 (pl) 2005-02-07

Family

ID=22860145

Family Applications (1)

Application Number Title Priority Date Filing Date
PL01366630A PL366630A1 (pl) 2000-08-30 2001-08-21 Selektywne cykliczne peptydy

Country Status (35)

Country Link
US (1) US7045591B2 (pl)
EP (1) EP1315750B1 (pl)
JP (1) JP4217069B2 (pl)
KR (1) KR100483300B1 (pl)
CN (1) CN100491396C (pl)
AR (2) AR030504A1 (pl)
AT (1) ATE353918T1 (pl)
AU (2) AU2001284026B2 (pl)
BR (1) BR0113637A (pl)
CA (1) CA2420058C (pl)
CY (1) CY1106562T1 (pl)
CZ (1) CZ2003584A3 (pl)
DE (1) DE60126624T2 (pl)
DK (1) DK1315750T3 (pl)
EC (1) ECSP034503A (pl)
ES (1) ES2280393T3 (pl)
HR (1) HRP20030126B1 (pl)
HU (1) HUP0303078A3 (pl)
IL (2) IL154575A0 (pl)
JO (1) JO2454B1 (pl)
MA (1) MA27681A1 (pl)
MX (1) MXPA03001721A (pl)
MY (1) MY137457A (pl)
NO (1) NO20030916D0 (pl)
NZ (1) NZ523989A (pl)
PA (1) PA8527201A1 (pl)
PE (1) PE20020483A1 (pl)
PL (1) PL366630A1 (pl)
PT (1) PT1315750E (pl)
RU (1) RU2239642C1 (pl)
SI (1) SI1315750T1 (pl)
TW (1) TWI248941B (pl)
WO (1) WO2002018437A2 (pl)
YU (1) YU15603A (pl)
ZA (1) ZA200301015B (pl)

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EP1409521A2 (en) * 2001-07-12 2004-04-21 Merck & Co., Inc. Cyclic peptides as potent and selective melanocortin-4 receptor agonists
US7456184B2 (en) 2003-05-01 2008-11-25 Palatin Technologies Inc. Melanocortin receptor-specific compounds
US7732451B2 (en) 2001-08-10 2010-06-08 Palatin Technologies, Inc. Naphthalene-containing melanocortin receptor-specific small molecule
US7354923B2 (en) 2001-08-10 2008-04-08 Palatin Technologies, Inc. Piperazine melanocortin-specific compounds
US7718802B2 (en) 2001-08-10 2010-05-18 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
US7655658B2 (en) 2001-08-10 2010-02-02 Palatin Technologies, Inc. Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds
AU2002331064B2 (en) 2001-08-10 2007-08-23 Palatin Technologies, Inc. Peptidomimetics of biologically active metallopeptides
AU2003248888A1 (en) 2002-07-09 2004-01-23 Palatin Technologies, Inc. Peptide composition for treatment of sexual dysfunction
US7968548B2 (en) 2003-05-01 2011-06-28 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine compounds with diamine groups
US7727990B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Melanocortin receptor-specific piperazine and keto-piperazine compounds
US7727991B2 (en) 2003-05-01 2010-06-01 Palatin Technologies, Inc. Substituted melanocortin receptor-specific single acyl piperazine compounds
MXPA05011830A (es) 2003-05-09 2006-01-26 Novo Nordisk As Peptidos para uso en el tratamiento de la obesidad.
EP1625158A2 (en) * 2003-05-09 2006-02-15 Novo Nordisk A/S Peptides for use in treating obesity
EP1644023A2 (en) * 2003-06-19 2006-04-12 Eli Lilly And Company Melanocortin recptor 4(mc4) agonists and their uses
WO2005000338A1 (en) * 2003-06-19 2005-01-06 Eli Lilly And Company Uses of melanocortin-3 receptor (mc3r) agonist peptides
US7084111B2 (en) 2003-06-23 2006-08-01 University Of Florida Research Foundation, Inc. Melanocortin receptor templates, peptides, and use thereof
CN101497654A (zh) * 2003-09-30 2009-08-05 诺沃挪第克公司 黑皮素受体激动剂
US7550602B1 (en) * 2004-01-14 2009-06-23 Palatin Technologies, Inc. Small molecule compositions for sexual dysfunction
US6974187B2 (en) * 2004-01-28 2005-12-13 Tachi-S Co., Ltd. Vehicle seat structure
JP2007530674A (ja) * 2004-03-29 2007-11-01 イーライ リリー アンド カンパニー 連続注入によって投与されるメラノコルチン−４受容体（ｍｃ４ｒ）アゴニストペプチドの使用
KR101092716B1 (ko) * 2004-04-08 2011-12-09 아스테라스 세이야쿠 가부시키가이샤 화합물 ｗｓ727713
US7709484B1 (en) 2004-04-19 2010-05-04 Palatin Technologies, Inc. Substituted melanocortin receptor-specific piperazine compounds
EP1809665A2 (en) * 2004-11-04 2007-07-25 Novo Nordisk A/S Mc4r selective peptides and their use in the treatment of obesity
CN101052650A (zh) * 2004-11-04 2007-10-10 诺和诺德公司 用于治疗肥胖的新颖的肽类
EP1809666A2 (en) * 2004-11-04 2007-07-25 Novo Nordisk A/S Peptides for use in the treating obesity
WO2006048451A1 (en) * 2004-11-04 2006-05-11 Novo Nordisk A/S Peptides for use in the treatment of obesity
WO2006129317A1 (en) * 2005-05-31 2006-12-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem BACKBONE CYCLIZED MELANOCORTIN STIMULATING HORMONE (α S ) ANALOGS
EP1893240A2 (en) * 2005-06-13 2008-03-05 Nastech Pharmaceutical Company Inc. Transmucosal delivery of peptide derivatives
US20070025902A1 (en) * 2005-07-15 2007-02-01 3M Innovative Properties Company Recovery of fluorinated carboxylic acid from adsorbent particles
US20080015304A1 (en) 2006-07-13 2008-01-17 Klaus Hintzer Aqueous emulsion polymerization process for producing fluoropolymers
GB2430437A (en) * 2005-09-27 2007-03-28 3M Innovative Properties Co Method of making a fluoropolymer
US7834017B2 (en) 2006-08-11 2010-11-16 Palatin Technologies, Inc. Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents
CA2673229A1 (en) * 2006-12-29 2008-07-10 F. Hoffmann-La Roche Ag Methods for the synthesis of cyclic peptides
US20100084343A1 (en) * 2007-02-16 2010-04-08 Mader Brian T System and process for the removal of fluorochemicals from water
US20080264864A1 (en) * 2007-04-27 2008-10-30 3M Innovative Properties Company PROCESS FOR REMOVING FLUORINATED EMULSIFIER FROM FLUOROPOLMER DISPERSIONS USING AN ANION-EXCHANGE RESIN AND A pH-DEPENDENT SURFACTANT AND FLUOROPOLYMER DISPERSIONS CONTAINING A pH-DEPENDENT SURFACTANT
EP2148692B1 (en) * 2007-05-25 2017-01-25 Ipsen Pharma S.A.S. Melanocortin receptor ligands modified with hydantoin
US8258313B2 (en) 2007-07-19 2012-09-04 Tokuyama Corporation Compound having hydantoin ring and method of producing the same
MX2010010407A (es) 2008-03-27 2010-10-25 Gruenenthal Gmbh Derivados de 4-aminociclohexanos sustituidos.
WO2009118163A1 (de) * 2008-03-27 2009-10-01 Grünenthal GmbH (hetero-)aryl-cyclohexan-derivate
JP5628796B2 (ja) 2008-06-09 2014-11-19 パラティン テクノロジーズ, インコーポレイテッドPalatin Technologies, Inc. 性的不能の治療用のメラノコルチンレセプタ特異的ペプチド
AR072072A1 (es) * 2008-06-09 2010-08-04 Palatin Technologies Inc Peptidos especificos del receptor de melanocortina para el tratamiento de la obesidad / 669
UY32690A (es) 2009-06-08 2011-01-31 Astrazeneca Ab Péptidos específicos para receptores de melanocortina
WO2010144341A2 (en) 2009-06-08 2010-12-16 Palatin Technologies, Inc. Lactam-bridged melanocortin receptor-specific peptides
WO2010144344A2 (en) * 2009-06-08 2010-12-16 Palatin Technologies, Inc. Melanocortin receptor-specific peptides
AU2010321738B2 (en) 2009-11-23 2016-07-14 Palatin Technologies, Inc. Melanocortin-1 receptor-specific cyclic peptides
EA201290295A1 (ru) 2009-11-23 2013-01-30 Палатин Текнолоджиз, Инк. Специфичные к рецептору меланокортина-1 линейные пептиды
EP2970388B1 (en) * 2013-03-15 2018-07-25 Rhythm Pharmaceuticals, Inc. Peptide compositions
GB201416352D0 (en) * 2014-09-16 2014-10-29 Shire Internat Gmbh Spirocyclic derivatives
GB201416351D0 (en) * 2014-09-16 2014-10-29 Shire Internat Gmbh Heterocyclic derivatives
WO2016046301A1 (en) * 2014-09-26 2016-03-31 Bayer Pharma Aktiengesellschaft Stabilized adrenomedullin derivatives and use thereof
US11542302B2 (en) 2015-10-15 2023-01-03 Arizona Board Of Regents On Behalf Of The University Of Arizona Modulators of melanocortin receptors for the treatment of depression and anxiety
WO2017066754A1 (en) 2015-10-15 2017-04-20 The Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for the treatment of depression and anxiety
US10899793B2 (en) 2016-05-27 2021-01-26 Regents Of The University Of Minnesota Melanocortin ligands and methods of use thereof
US20190255142A1 (en) * 2016-10-17 2019-08-22 Arizona Board Of Regents On Behalf Of The University Of Arizona Novel modulators of melanocortin receptors for the treatment of depression and anxiety
US11124541B2 (en) 2016-10-18 2021-09-21 Regents Of The University Of Minnesota Chimeric melanocortin ligands and methods of use thereof
CN106496005B (zh) * 2016-10-20 2019-04-09 上海毕得医药科技有限公司 一种4-(4-氯苯基)环己酮的合成方法
CN106496008A (zh) * 2016-10-20 2017-03-15 上海毕得医药科技有限公司 一种合成4‑(4‑氯苯基)环己酮的方法
US10745444B2 (en) * 2017-04-17 2020-08-18 National Tsing Hua University Cyclopeptide, pharmaceutical or cosmetic composition comprising the same and method for preparing the same
US11332499B2 (en) 2018-08-16 2022-05-17 Regents Of The University Of Minnesota Cyclic peptides and methods of use thereof
CN118530294B (zh) * 2024-05-10 2025-02-14 浙江大学 一种芳基二胺固载连接子、其前体以及制备方法和应用

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DE4237456A1 (de) * 1992-11-06 1994-05-11 Merck Patent Gmbh Cyclopeptide
US5811391A (en) 1994-08-25 1998-09-22 Cytel Corporation Cyclic CS-1 peptidomimetics, compositions and methods of using same
US5731408A (en) * 1995-04-10 1998-03-24 Arizona Board Of Regents On Behalf Of The University Of Arizona Peptides having potent antagonist and agonist bioactivities at melanocortin receptors
US5858972A (en) 1996-01-11 1999-01-12 La Jolla Cancer Research Foundation Antithrombotic agents and methods of use
SE9700620D0 (sv) * 1997-02-21 1997-02-21 Wapharm Ab Cykliska peptider med selektivitet för MSH-receptor subtyper
ATE393783T1 (de) 1999-03-29 2008-05-15 Procter & Gamble Melanocortinrezeptor-liganden

Also Published As

Publication number Publication date
CA2420058A1 (en) 2002-03-07
CY1106562T1 (el) 2012-01-25
HUP0303078A2 (hu) 2003-12-29
MXPA03001721A (es) 2003-05-27
CN1451017A (zh) 2003-10-22
IL154575A (en) 2008-12-29
NO20030916L (no) 2003-02-27
EP1315750A2 (en) 2003-06-04
AR030504A1 (es) 2003-08-20
MA27681A1 (fr) 2006-01-02
SI1315750T1 (sl) 2007-06-30
TWI248941B (en) 2006-02-11
BR0113637A (pt) 2004-02-25
DE60126624D1 (de) 2007-03-29
PT1315750E (pt) 2007-05-31
AR061422A2 (es) 2008-08-27
WO2002018437A3 (en) 2002-06-06
ZA200301015B (en) 2004-05-05
HUP0303078A3 (en) 2012-02-28
AU8402601A (en) 2002-03-13
JP4217069B2 (ja) 2009-01-28
US20020143141A1 (en) 2002-10-03
MY137457A (en) 2009-01-30
YU15603A (sh) 2006-05-25
NO20030916D0 (no) 2003-02-27
HRP20030126A2 (en) 2005-10-31
KR20030061788A (ko) 2003-07-22
JP2004507558A (ja) 2004-03-11
CZ2003584A3 (cs) 2003-08-13
KR100483300B1 (ko) 2005-04-15
RU2239642C1 (ru) 2004-11-10
PA8527201A1 (es) 2002-04-25
US7045591B2 (en) 2006-05-16
PE20020483A1 (es) 2002-06-06
HRP20030126B1 (en) 2009-01-31
WO2002018437A2 (en) 2002-03-07
ATE353918T1 (de) 2007-03-15
CA2420058C (en) 2009-04-07
IL154575A0 (en) 2003-09-17
JO2454B1 (en) 2008-10-09
CN100491396C (zh) 2009-05-27
AU2001284026B2 (en) 2007-03-01
NZ523989A (en) 2004-08-27
ES2280393T3 (es) 2007-09-16
DE60126624T2 (de) 2007-11-22
EP1315750B1 (en) 2007-02-14
DK1315750T3 (da) 2007-06-11
ECSP034503A (es) 2003-04-25

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