PL366780A1 - Sulfonamidy 2-(podstawionego-amino) benzoksazolu jako inhibitory proteazy HIV o szerokim zakresie działania - Google Patents

Sulfonamidy 2-(podstawionego-amino) benzoksazolu jako inhibitory proteazy HIV o szerokim zakresie działania

Info

Publication number: PL366780A1
Authority: PL; Poland
Prior art keywords: broadspectrum; amino; protease inhibitors; hiv protease; benzoxazole sulfonamide
Prior art date: 2001-05-11

Application number

PL02366780A

Other languages

English (en)

Other versions

PL209029B1 (pl

Inventor

Dominique Louis Nestor Ghislain Surleraux

Sandrine Marie Helene Vendeville

Wim Gaston Verschueren

Bethune Marie-Pierre T.M.M.G. De

Kock Herman Augustinus De

Abdellah Tahri

Original Assignee

Tibotec Pharmaceuticals Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-11

Filing date

2002-05-10

Publication date

2005-02-07

2002-05-10 Application filed by Tibotec Pharmaceuticals Ltd. filed Critical Tibotec Pharmaceuticals Ltd.

2005-02-07 Publication of PL366780A1 publication Critical patent/PL366780A1/pl

2011-07-29 Publication of PL209029B1 publication Critical patent/PL209029B1/pl

Links

SDCCPSGJFZFNPB-UHFFFAOYSA-N 2-amino-3h-1,3-benzoxazole-2-sulfonamide Chemical compound C1=CC=C2OC(N)(S(N)(=O)=O)NC2=C1 SDCCPSGJFZFNPB-UHFFFAOYSA-N 0.000 title 1
239000004030 hiv protease inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)

PL366780A 2001-05-11 2002-05-10 Pochodne 2-aminobenzoksazolo-sulfonamidów jako inhibitory proteazy HIV, oraz kompozycje zawierające te związki PL209029B1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01201732		2001-05-11

Publications (2)

Publication Number	Publication Date
PL366780A1 true PL366780A1 (pl)	2005-02-07
PL209029B1 PL209029B1 (pl)	2011-07-29

Family

ID=8180286

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL366780A PL209029B1 (pl)	2001-05-11	2002-05-10	Pochodne 2-aminobenzoksazolo-sulfonamidów jako inhibitory proteazy HIV, oraz kompozycje zawierające te związki

Country Status (31)

Country	Link
US (2)	US7622490B2 (pl)
EP (1)	EP1387842B1 (pl)
JP (1)	JP4467889B2 (pl)
KR (1)	KR100878853B1 (pl)
CN (1)	CN100549007C (pl)
AP (1)	AP1652A (pl)
AR (1)	AR035970A1 (pl)
AT (1)	ATE429431T1 (pl)
AU (1)	AU2002310818B2 (pl)
BG (1)	BG66350B1 (pl)
BR (1)	BR0209594A (pl)
CA (1)	CA2444895C (pl)
CY (1)	CY1109247T1 (pl)
CZ (1)	CZ304524B6 (pl)
DE (1)	DE60232067D1 (pl)
DK (1)	DK1387842T3 (pl)
EA (1)	EA009590B1 (pl)
EE (1)	EE05307B1 (pl)
ES (1)	ES2325809T3 (pl)
HR (1)	HRP20031026B1 (pl)
HU (1)	HUP0400438A3 (pl)
IL (1)	IL158093A0 (pl)
MX (1)	MXPA03010258A (pl)
NO (1)	NO326883B1 (pl)
NZ (1)	NZ529250A (pl)
OA (1)	OA13134A (pl)
PL (1)	PL209029B1 (pl)
PT (1)	PT1387842E (pl)
SK (1)	SK287952B6 (pl)
WO (1)	WO2002092595A1 (pl)
ZA (1)	ZA200307799B (pl)

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US7364752B1 (en)	1999-11-12	2008-04-29	Abbott Laboratories	Solid dispersion pharamaceutical formulations
WO2001034119A2 (en)	1999-11-12	2001-05-17	Abbott Laboratories	Inhibitors of crystallization in a solid dispersion
DE10026698A1 (de)	2000-05-30	2001-12-06	Basf Ag	Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US20040009890A1 (en)	2002-01-07	2004-01-15	Erickson John W.	Broad spectrum inhibitors
US7157489B2 (en)	2002-03-12	2007-01-02	The Board Of Trustees Of The University Of Illinois	HIV protease inhibitors
US8025899B2 (en)	2003-08-28	2011-09-27	Abbott Laboratories	Solid pharmaceutical dosage form
PL1670773T3 (pl) *	2003-09-30	2007-06-29	Tibotec Pharm Ltd	Sposób wytwarzania sulfonamidów benzoksazolu i ich związków pośrednich
US8193227B2 (en)	2003-12-11	2012-06-05	Abbott Laboratories	HIV protease inhibiting compounds
US20050131042A1 (en) *	2003-12-11	2005-06-16	Flentge Charles A.	HIV protease inhibiting compounds
DE602004021640D1 (de)	2003-12-23	2009-07-30	Tibotec Pharm Ltd	Verfahren zur herstellung von (1s,2r)-3-ää(4-aminophenyl)sulfonylü(isobutyl)aminoü-1-benzyl-2-hydroxypropylcarbamidsäure-(3r,3as,6ar)-hexahydrofuroä2,3-büfuran-3-ylester
RS51073B (sr)	2003-12-23	2010-10-31	Tibotec Pharmaceuticals Ltd.	Proces za pripremanje (3r,3as,6ar)-heksahidrofuro│2,3-b│ furan-3-il (1s,2r)-3-││(4-aminofenil) sulfonil│(izobutil) amino │-1-benzil-2-hidroksipropilkarbamata
MXPA06012909A (es) *	2004-05-07	2007-09-06	Sequoia Pharmaceuticals Inc	Inhibidores de proteasa retroviral repelente de resistencia.
AU2006217922B2 (en)	2005-02-25	2012-04-05	Janssen Sciences Ireland Uc	Protease inhibitor precursor synthesis
AR053845A1 (es) *	2005-04-15	2007-05-23	Tibotec Pharm Ltd	5-tiazolilmetil[(1s,2r)-3-[[(2-amino-6-benzoxazolil)sulfonil)](2-metilpropil)amino]-2-hidroxi-1-(fenilmetil)propil]carbamato como mejorador de farmacos metabolizados por el citocromo p450
US20120220520A1 (en) *	2006-10-17	2012-08-30	Van T Klooster Gerben Albert Eleutherius	Bioavailable combinations for hcv treatment
WO2014194519A1 (en)	2013-06-07	2014-12-11	Merck Sharp & Dohme Corp.	Imidazole derivatives and methods of use thereof for improving pharmacokinetics of drug

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EP0445926B1 (en)	1990-03-09	1996-08-21	Milliken Research Corporation	Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation
US5145684A (en)	1991-01-25	1992-09-08	Sterling Drug Inc.	Surface modified drug nanoparticles
ATE154800T1 (de) *	1992-08-25	1997-07-15	Searle & Co	N-(alkanoylamino-2-hydroxypropyl)-sulfonamide verwendbar als retrovirale proteaseninhibitoren
PH30929A (en)	1992-09-03	1997-12-23	Janssen Pharmaceutica Nv	Beads having a core coated with an antifungal and a polymer.
AU7669794A (en) *	1993-08-24	1995-03-21	G.D. Searle & Co.	Hydroxyethylamino sulphonamides useful as retroviral protease inhibitors
SK283569B6 (sk)	1993-10-01	2003-09-11	Astra Aktiebolag	Spôsob spracovania jemne deleného práškového liečiva, zariadenie na vykonávanie tohto spôsobu a aglomeráty vyrobené týmto spôsobom
WO1996022287A1 (en)	1995-01-20	1996-07-25	G.D. Searle & Co.	Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors
US5756533A (en) *	1995-03-10	1998-05-26	G.D. Searle & Co.	Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
AU717598B2 (en)	1995-03-10	2000-03-30	G.D. Searle & Co.	Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US6150556A (en) *	1995-03-10	2000-11-21	G. D. Dearle & Co.	Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US5705500A (en) *	1995-03-10	1998-01-06	G.D. Searle & Co.	Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
JP2000515488A (ja) *	1995-11-15	2000-11-21	ジー．ディー．サールアンドカンパニー	置換スルホニルアルカノイルアミノヒドロキシエチルアミノスルホンアミドレトロウイルスプロテアーゼ阻害剤
DK0904060T3 (da)	1996-05-20	2004-04-13	Janssen Pharmaceutica Nv	Antifungale præparater med forbedret biotilgængelighed
WO1998042318A1 (en)	1997-03-26	1998-10-01	Janssen Pharmaceutica N.V.	Pellets having a core coated with an antifungal and a polymer
GB9717849D0 (en)	1997-08-23	1997-10-29	Seal Sands Chemicals Limited	Preparation of pyridene derivatives
US6436989B1 (en)	1997-12-24	2002-08-20	Vertex Pharmaceuticals, Incorporated	Prodrugs of aspartyl protease inhibitors
BR9814484A (pt)	1997-12-24	2000-10-10	Vertex Pharma	"pró-drogas de inibidores de aspartil protease"
WO1999033795A1 (en)	1997-12-24	1999-07-08	Vertex Pharmaceuticals Incorporated	Prodrugs of aspartyl protease inhibitors
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JP4776775B2 (ja)	1998-06-23	2011-09-21	アメリカ合衆国	Ｈｉｖ感染哺乳動物を治療するための医薬組成物
WO1999067254A2 (en) *	1998-06-23	1999-12-29	The United States Of America Represented By The Secretary, Department Of Health And Human Services	Multi-drug resistant retroviral protease inhibitors and use thereof
OA12464A (en) *	2001-04-09	2006-05-24	Tibotec Pharm Ltd	Broadspectrum 2-(substituted-amino)-benzoxazole sulfonamide HIV protease inhibitors.

2002
- 2002-05-10 EE EEP200300547A patent/EE05307B1/xx not_active IP Right Cessation
- 2002-05-10 BR BR0209594-7A patent/BR0209594A/pt not_active IP Right Cessation
- 2002-05-10 CZ CZ2003-3290A patent/CZ304524B6/cs not_active IP Right Cessation
- 2002-05-10 AP APAP/P/2003/002904A patent/AP1652A/en active
- 2002-05-10 IL IL15809302A patent/IL158093A0/xx not_active IP Right Cessation
- 2002-05-10 MX MXPA03010258A patent/MXPA03010258A/es active IP Right Grant
- 2002-05-10 OA OA1200300277A patent/OA13134A/en unknown
- 2002-05-10 AU AU2002310818A patent/AU2002310818B2/en not_active Ceased
- 2002-05-10 WO PCT/EP2002/005212 patent/WO2002092595A1/en not_active Ceased
- 2002-05-10 HR HRP20031026AA patent/HRP20031026B1/xx not_active IP Right Cessation
- 2002-05-10 CA CA2444895A patent/CA2444895C/en not_active Expired - Fee Related
- 2002-05-10 SK SK1490-2003A patent/SK287952B6/sk not_active IP Right Cessation
- 2002-05-10 PL PL366780A patent/PL209029B1/pl unknown
- 2002-05-10 EP EP02735354A patent/EP1387842B1/en not_active Expired - Lifetime
- 2002-05-10 KR KR1020037013145A patent/KR100878853B1/ko not_active Expired - Fee Related
- 2002-05-10 DK DK02735354T patent/DK1387842T3/da active
- 2002-05-10 AR ARP020101722A patent/AR035970A1/es active IP Right Grant
- 2002-05-10 HU HU0400438A patent/HUP0400438A3/hu not_active IP Right Cessation
- 2002-05-10 JP JP2002589479A patent/JP4467889B2/ja not_active Expired - Fee Related
- 2002-05-10 AT AT02735354T patent/ATE429431T1/de active
- 2002-05-10 US US10/474,485 patent/US7622490B2/en not_active Expired - Fee Related
- 2002-05-10 CN CNB028097416A patent/CN100549007C/zh not_active Expired - Fee Related
- 2002-05-10 DE DE60232067T patent/DE60232067D1/de not_active Expired - Lifetime
- 2002-05-10 PT PT02735354T patent/PT1387842E/pt unknown
- 2002-05-10 EA EA200301234A patent/EA009590B1/ru not_active IP Right Cessation
- 2002-05-10 NZ NZ529250A patent/NZ529250A/en not_active IP Right Cessation
- 2002-05-10 ES ES02735354T patent/ES2325809T3/es not_active Expired - Lifetime
2003
- 2003-10-06 ZA ZA2003/07799A patent/ZA200307799B/en unknown
- 2003-11-03 BG BG108309A patent/BG66350B1/bg unknown
- 2003-11-10 NO NO20034988A patent/NO326883B1/no not_active IP Right Cessation
2009
- 2009-07-21 CY CY20091100774T patent/CY1109247T1/el unknown
- 2009-10-07 US US12/575,216 patent/US7863306B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HUP0400438A2 (hu)	2004-08-30
AR035970A1 (es)	2004-07-28
EA200301234A1 (ru)	2004-04-29
US7622490B2 (en)	2009-11-24
ES2325809T3 (es)	2009-09-18
PL209029B1 (pl)	2011-07-29
JP2004534757A (ja)	2004-11-18
DK1387842T3 (da)	2009-08-10
EP1387842A1 (en)	2004-02-11
HUP0400438A3 (en)	2007-08-28
HRP20031026A2 (en)	2005-10-31
SK14902003A3 (sk)	2004-07-07
WO2002092595A1 (en)	2002-11-21
CY1109247T1 (el)	2014-07-02
BG66350B1 (bg)	2013-08-30
CN1507446A (zh)	2004-06-23
AP1652A (en)	2006-08-11
JP4467889B2 (ja)	2010-05-26
ATE429431T1 (de)	2009-05-15
AP2003002904A0 (en)	2003-12-31
MXPA03010258A (es)	2005-03-07
HRP20031026B1 (hr)	2012-07-31
EP1387842B1 (en)	2009-04-22
US20040106661A1 (en)	2004-06-03
EE05307B1 (et)	2010-06-15
BR0209594A (pt)	2004-03-30
DE60232067D1 (de)	2009-06-04
CA2444895C (en)	2011-02-15
NO326883B1 (no)	2009-03-09
ZA200307799B (en)	2005-03-30
CZ304524B6 (cs)	2014-06-18
CZ20033290A3 (cs)	2004-05-12
NO20034988D0 (no)	2003-11-10
IL158093A0 (en)	2004-03-28
KR20040022417A (ko)	2004-03-12
OA13134A (en)	2006-12-13
BG108309A (bg)	2004-12-30
SK287952B6 (sk)	2012-06-04
NZ529250A (en)	2005-05-27
CN100549007C (zh)	2009-10-14
AU2002310818B2 (en)	2007-12-13
PT1387842E (pt)	2009-07-20
EE200300547A (et)	2004-02-16
CA2444895A1 (en)	2002-11-21
HK1062912A1 (en)	2004-12-03
EA009590B1 (ru)	2008-02-28
KR100878853B1 (ko)	2009-01-15
US7863306B2 (en)	2011-01-04
US20100029632A1 (en)	2010-02-04

Publication	Publication Date	Title
GB0125445D0 (en)	2001-12-12	Protease Inhibitors
AP2003002856A0 (en)	2003-09-30	Broadspectrum 2-(substitutted-amino)-benzothiazolesulphonamide HIV protease inhibitors.
AU2002305926A1 (en)	2002-10-08	Cysteine protease inhibitors
EP1483254A4 (en)	2005-06-08	INHIBITORS OF ANTI-RESISTANCE RETROVIRAL PROTEASE
IL158093A0 (en)	2004-03-28	Broadspectrum 2-amino-benzoxazole sulfonamide hiv protease inhibitors
AP1878A (en)	2008-08-13	Broadspectrum 2-amino-benzothiazole sulfonamide HIV protease inhibitors.
PL375307A1 (pl)	2005-11-28	Podstawione oksoindolo sulfonamidy jako inhibitory proteazy HIV o szerokim zakresie działania
ZA200410156B (en)	2005-11-30	Broadspectrum substituted benzisoxazole sulfonamide hiv protease inhibitors
IL162574A0 (en)	2005-11-20	Broadspectrum heterocyclic substituted phenyl containing sulfonamide hiv protease inhibitors
IL158092A0 (en)	2004-03-28	Broadspectrum 2- (substituted-amino)-benzoxazole sulfonamide hiv protease inhibitors
AU2002360673A8 (en)	2003-06-30	Gp41 inhibitor
EP1401453A4 (en)	2005-04-06	PROTEASE INHIBITORS
HRP20040936A2 (en)	2005-10-31	Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors
GB0123467D0 (en)	2001-11-21	Carbocyclic HIV Protease inhibitors
GB0028483D0 (en)	2001-01-10	Hydroxyethylamine HIV protease inhibitors
AU2003287325A8 (en)	2004-06-03	N-cycloalkylglycines as hiv protease inhibitors
ZA200500926B (en)	2006-03-29	Broadspectrum 2-amino-benzothiazole sulfonamide HIV protease inhibitors
AU2002255485A8 (en)	2008-01-10	Hiv/fiv protease inhibitors
IL160626A0 (en)	2004-07-25	Antiviral protease inhibitors
HK1079684A (en)	2006-04-13	Broadspectrum 2-amino-benzothiazole sulfonamide hiv protease inhibitors
AU2002323648A1 (en)	2003-04-01	Sulfonamide compounds as protease inhibitors
AU2002311768A1 (en)	2002-10-08	Aminopyrrolidine sulfonamides as serine protease inhibitors
AU2002341701A1 (en)	2003-04-01	Bis-amino acid sulfonamides as hiv protease inhibitors
HK1079769A (zh)	2006-04-13	取代的羟吲哚磺酰胺类广谱hiv蛋白酶抑制剂
AU2002356595A1 (en)	2003-05-26	Serin protease inhibitors