PL368502A1 - Thieno[2,3-d]pyrimidines with combined lh and fsh agonistic activity - Google Patents

Thieno[2,3-d]pyrimidines with combined lh and fsh agonistic activity

Info

Publication number: PL368502A1
Authority: PL; Poland
Prior art keywords: thieno; pyrimidines; combined; agonistic activity; fsh agonistic
Prior art date: 2001-09-04

Application number

PL02368502A

Other languages

English (en)

Polish (pl)

Inventor

Robert Gerard Jules Marie Hanssen

Cornelis Marius Timmers

Original Assignee

Akzo Nobel N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-04

Filing date

2002-08-29

Publication date

2005-04-04

2002-08-29 Application filed by Akzo Nobel N.V. filed Critical Akzo Nobel N.V.

2005-04-04 Publication of PL368502A1 publication Critical patent/PL368502A1/xx

Links

DDWBRNXDKNIQDY-UHFFFAOYSA-N thieno[2,3-d]pyrimidine Chemical class N1=CN=C2SC=CC2=C1 DDWBRNXDKNIQDY-UHFFFAOYSA-N 0.000 title abstract 2
230000001270 agonistic effect Effects 0.000 title 1
102000008175 FSH Receptors Human genes 0.000 abstract 1
108010060374 FSH Receptors Proteins 0.000 abstract 1
102000023108 LH Receptors Human genes 0.000 abstract 1
108010011942 LH Receptors Proteins 0.000 abstract 1
230000003213 activating effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000035558 fertility Effects 0.000 abstract 1
125000000592 heterocycloalkyl group Chemical group 0.000 abstract 1
230000001105 regulatory effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PL02368502A 2001-09-04 2002-08-29 Thieno[2,3-d]pyrimidines with combined lh and fsh agonistic activity PL368502A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01203327		2001-09-04

Publications (1)

Publication Number	Publication Date
PL368502A1 true PL368502A1 (en)	2005-04-04

Family

ID=8180876

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL02368502A PL368502A1 (en)	2001-09-04	2002-08-29	Thieno[2,3-d]pyrimidines with combined lh and fsh agonistic activity

Country Status (28)

Country	Link
US (1)	US7317006B2 (es)
EP (1)	EP1427733B1 (es)
JP (1)	JP4262092B2 (es)
KR (1)	KR100900018B1 (es)
CN (1)	CN1246324C (es)
AR (1)	AR036407A1 (es)
AT (1)	ATE345345T1 (es)
AU (1)	AU2002337035B2 (es)
BR (1)	BR0211938A (es)
CA (1)	CA2456901C (es)
CY (1)	CY1106012T1 (es)
DE (1)	DE60216128T2 (es)
DK (1)	DK1427733T3 (es)
ES (1)	ES2275005T3 (es)
HR (1)	HRP20040202A2 (es)
HU (1)	HUP0401444A3 (es)
IL (1)	IL160084A0 (es)
IS (1)	IS2424B (es)
MX (1)	MXPA04002045A (es)
NO (1)	NO20040927L (es)
NZ (1)	NZ531340A (es)
PE (1)	PE20030439A1 (es)
PL (1)	PL368502A1 (es)
PT (1)	PT1427733E (es)
RU (1)	RU2298011C2 (es)
TW (1)	TWI228508B (es)
WO (1)	WO2003020726A1 (es)
ZA (1)	ZA200401455B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6890923B2 (en) *	2002-12-16	2005-05-10	Astrazeneca Ab	Compounds
GB0315950D0 (en) *	2003-06-11	2003-08-13	Xention Discovery Ltd	Compounds
GB0525164D0 (en) *	2005-12-09	2006-01-18	Xention Discovery Ltd	Compounds
CN100430403C (zh) *	2006-10-13	2008-11-05	中国科学院上海有机化学研究所	3-芳基-5,6-取代噻吩并嘧啶-4-羰基-2-巯基乙腈、合成方法和用途
US20090118276A1 (en) *	2007-11-02	2009-05-07	Wyeth	Thienopyrimidines, thienopyridines, and pyrrolopyrimidines as b-raf inhibitors
TWI389913B (zh) *	2008-09-08	2013-03-21	Lg Life Sciences Ltd	并合雜環化合物
US8741259B2 (en) *	2008-10-20	2014-06-03	Marvin C. Gershengorn	Low molecular weight thyroid stimulating hormone receptor (TSHR) agonists
GB0905525D0 (en)	2009-03-31	2009-05-13	Univ Leiden	Compounds and uses
EP2525658B1 (de)	2010-01-22	2017-03-01	Bayer Intellectual Property GmbH	Akarizide und/oder insektizide wirkstoffkombinationen
US9206154B2 (en)	2010-04-08	2015-12-08	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Inverse agonists and neutral antagonists for the TSH receptor
WO2016029372A1 (en)	2014-08-27	2016-03-03	The Procter & Gamble Company	Wearable article having elastic belt
WO2016029375A1 (en)	2014-08-27	2016-03-03	The Procter & Gamble Company	Wearable article having elastic belt
RU2619091C2 (ru) *	2015-10-13	2017-05-11	Министерство Промышленности И Торговли Рф	Цилиндрический термоэмиссионный катод
CN108883011B (zh)	2016-04-08	2021-05-07	宝洁公司	具有艺术作品的可穿着制品
CA3258277A1 (en) *	2022-06-08	2023-12-14	Icahn School Of Medicine At Mount Sinai	METHOD FOR OBESITY TREATMENT WITH A LUTEINIZING HORMONE RECEPTOR AGONIST

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2054784T3 (es)	1987-08-08	1994-08-16	Akzo Nv	Un metodo para la fabricacion de un implante.
TW564247B (en) *	1999-04-08	2003-12-01	Akzo Nobel Nv	Bicyclic heteraromatic compound

2002
- 2002-07-22 TW TW091116284A patent/TWI228508B/zh not_active IP Right Cessation
- 2002-08-29 PT PT02772230T patent/PT1427733E/pt unknown
- 2002-08-29 EP EP02772230A patent/EP1427733B1/en not_active Expired - Lifetime
- 2002-08-29 BR BR0211938-2A patent/BR0211938A/pt not_active IP Right Cessation
- 2002-08-29 KR KR1020047003095A patent/KR100900018B1/ko not_active Expired - Fee Related
- 2002-08-29 PL PL02368502A patent/PL368502A1/xx not_active Application Discontinuation
- 2002-08-29 CN CNB028172604A patent/CN1246324C/zh not_active Expired - Fee Related
- 2002-08-29 US US10/488,482 patent/US7317006B2/en not_active Expired - Lifetime
- 2002-08-29 DK DK02772230T patent/DK1427733T3/da active
- 2002-08-29 HR HR20040202A patent/HRP20040202A2/hr not_active Application Discontinuation
- 2002-08-29 RU RU2004110042/04A patent/RU2298011C2/ru not_active IP Right Cessation
- 2002-08-29 ES ES02772230T patent/ES2275005T3/es not_active Expired - Lifetime
- 2002-08-29 JP JP2003524996A patent/JP4262092B2/ja not_active Expired - Fee Related
- 2002-08-29 DE DE60216128T patent/DE60216128T2/de not_active Expired - Lifetime
- 2002-08-29 MX MXPA04002045A patent/MXPA04002045A/es active IP Right Grant
- 2002-08-29 NZ NZ531340A patent/NZ531340A/en unknown
- 2002-08-29 CA CA2456901A patent/CA2456901C/en not_active Expired - Fee Related
- 2002-08-29 WO PCT/EP2002/009647 patent/WO2003020726A1/en not_active Ceased
- 2002-08-29 AU AU2002337035A patent/AU2002337035B2/en not_active Ceased
- 2002-08-29 HU HU0401444A patent/HUP0401444A3/hu unknown
- 2002-08-29 IL IL16008402A patent/IL160084A0/xx not_active IP Right Cessation
- 2002-08-29 AT AT02772230T patent/ATE345345T1/de not_active IP Right Cessation
- 2002-09-02 AR ARP020103309A patent/AR036407A1/es unknown
- 2002-09-03 PE PE2002000840A patent/PE20030439A1/es not_active Application Discontinuation
2004
- 2004-01-29 IS IS7130A patent/IS2424B/is unknown
- 2004-02-23 ZA ZA200401455A patent/ZA200401455B/en unknown
- 2004-03-03 NO NO20040927A patent/NO20040927L/no not_active Application Discontinuation
2007
- 2007-02-13 CY CY20071100189T patent/CY1106012T1/el unknown

Also Published As

Publication number	Publication date
CY1106012T1 (el)	2011-04-06
ES2275005T3 (es)	2007-06-01
WO2003020726A1 (en)	2003-03-13
RU2004110042A (ru)	2005-08-20
CA2456901A1 (en)	2003-03-13
IS2424B (is)	2008-10-15
KR20040029134A (ko)	2004-04-03
NZ531340A (en)	2005-08-26
PE20030439A1 (es)	2003-05-17
HRP20040202A2 (en)	2004-08-31
DE60216128T2 (de)	2007-09-27
US7317006B2 (en)	2008-01-08
ATE345345T1 (de)	2006-12-15
AR036407A1 (es)	2004-09-08
CN1551884A (zh)	2004-12-01
DK1427733T3 (da)	2007-03-19
ZA200401455B (en)	2004-11-19
DE60216128D1 (de)	2006-12-28
TWI228508B (en)	2005-03-01
KR100900018B1 (ko)	2009-06-01
EP1427733A1 (en)	2004-06-16
EP1427733B1 (en)	2006-11-15
JP2005505555A (ja)	2005-02-24
CA2456901C (en)	2011-01-04
IL160084A0 (en)	2004-06-20
RU2298011C2 (ru)	2007-04-27
BR0211938A (pt)	2004-09-21
AU2002337035B2 (en)	2008-04-24
JP4262092B2 (ja)	2009-05-13
NO20040927L (no)	2004-03-03
CN1246324C (zh)	2006-03-22
PT1427733E (pt)	2007-02-28
IS7130A (is)	2004-01-29
HUP0401444A3 (en)	2008-05-28
HUP0401444A2 (hu)	2004-11-29
MXPA04002045A (es)	2004-07-08
US20040180873A1 (en)	2004-09-16

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Legal Events

Date	Code	Title	Description
2010-09-30	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)