PL369171A1 - 17alfa-Alkilo-17beta-oksy-estratrieny i produkty pośrednie do ich wytwarzania, zastosowanie 17alfa-alkilo-17beta-oksy-estratrienów do wytwarzania środków leczniczych oraz preparaty farmaceutyczne - Google Patents

17alfa-Alkilo-17beta-oksy-estratrieny i produkty pośrednie do ich wytwarzania, zastosowanie 17alfa-alkilo-17beta-oksy-estratrienów do wytwarzania środków leczniczych oraz preparaty farmaceutyczne

Info

Publication number
PL369171A1
PL369171A1 PL02369171A PL36917102A PL369171A1 PL 369171 A1 PL369171 A1 PL 369171A1 PL 02369171 A PL02369171 A PL 02369171A PL 36917102 A PL36917102 A PL 36917102A PL 369171 A1 PL369171 A1 PL 369171A1
Authority
PL
Poland
Prior art keywords
estratrienes
17alpha
17beta
oxy
alkyl
Prior art date
Application number
PL02369171A
Other languages
English (en)
Other versions
PL207955B1 (pl
Inventor
Rolf Bohlmann
Nikolaus Heinrich
Rolf Jautelat
Jorg Kroll
Orlin Petrov
Andreas Reichel
Jena Hoffmann
Rosemarie Lichtner
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of PL369171A1 publication Critical patent/PL369171A1/pl
Publication of PL207955B1 publication Critical patent/PL207955B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Urology & Nephrology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL369171A 2001-11-27 2002-11-27 17α-Alkilo-17ß-oksy-estratrieny, ich zastosowanie oraz preparaty farmaceutyczne je zawierające PL207955B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10159217A DE10159217A1 (de) 2001-11-27 2001-11-27 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate

Publications (2)

Publication Number Publication Date
PL369171A1 true PL369171A1 (pl) 2005-04-18
PL207955B1 PL207955B1 (pl) 2011-02-28

Family

ID=7707804

Family Applications (1)

Application Number Title Priority Date Filing Date
PL369171A PL207955B1 (pl) 2001-11-27 2002-11-27 17α-Alkilo-17ß-oksy-estratrieny, ich zastosowanie oraz preparaty farmaceutyczne je zawierające

Country Status (25)

Country Link
US (2) US7018994B2 (pl)
EP (2) EP1916254A3 (pl)
JP (3) JP2005513039A (pl)
KR (1) KR100956912B1 (pl)
CN (2) CN100558741C (pl)
AR (1) AR037674A1 (pl)
AT (1) ATE396198T1 (pl)
AU (1) AU2002360949A1 (pl)
BR (1) BR0214469A (pl)
CA (1) CA2468412C (pl)
CY (1) CY1108279T1 (pl)
DE (2) DE10159217A1 (pl)
DK (1) DK1448591T3 (pl)
ES (1) ES2307819T3 (pl)
IL (2) IL162200A0 (pl)
MX (1) MXPA04005015A (pl)
NO (2) NO326241B1 (pl)
PE (1) PE20030727A1 (pl)
PL (1) PL207955B1 (pl)
PT (1) PT1448591E (pl)
RU (2) RU2285009C2 (pl)
TW (1) TWI256891B (pl)
UY (1) UY27552A1 (pl)
WO (1) WO2003045972A1 (pl)
ZA (2) ZA200405029B (pl)

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US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
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US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
PL2359808T3 (pl) 2006-08-09 2013-10-31 Intarcia Therapeutics Inc Osmotyczne systemy dostawcze i zespoły tłokowe
JP4724073B2 (ja) 2006-08-17 2011-07-13 富士通株式会社 レジストパターンの形成方法、半導体装置及びその製造方法
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EP2157967B1 (en) 2007-04-23 2013-01-16 Intarcia Therapeutics, Inc Suspension formulations of insulinotropic peptides and uses thereof
DE102007032800A1 (de) 2007-07-10 2009-01-15 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
EP2033948A1 (en) * 2007-08-30 2009-03-11 Bayer Schering Pharma Aktiengesellschaft Process for preparing Estrogen-antagonistic 11beta-Fluoro-17alpha-alkylestra-1,3,5 (10)-triene-3, 17-diols having a 7alpha-(xi-Alkylamino-omega-perfluoroalkyl)alkyl side chain and alpha-Alkyl(amino)-omega-perfluoro(alkyl)alkanes and processes for their preparation
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EP2070941A1 (en) 2007-12-14 2009-06-17 Bayer Schering Pharma Aktiengesellschaft Stereoselective synthesis of selective estrogen receptor down-regulators
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EP2240155B1 (en) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Devices, formulations, and methods for delivery of multiple beneficial agents
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DE102009034368A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034367A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de) 2009-07-21 2011-02-10 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de) 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
EP3323423B1 (en) 2009-09-28 2020-06-17 Intarcia Therapeutics, Inc Rapid establishment and/or termination of substantial steady-state drug delivery
DE102010007722A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
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PL2983671T4 (pl) 2013-04-11 2019-04-30 Bayer Pharma AG Postać dawkowania antagonisty receptora progesteronowego
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
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KR20240037175A (ko) 2016-05-16 2024-03-21 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
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US20040242551A1 (en) * 2003-05-28 2004-12-02 Schering Ag Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases

Also Published As

Publication number Publication date
PT1448591E (pt) 2008-09-19
CN1637015A (zh) 2005-07-13
CN1325507C (zh) 2007-07-11
DE10159217A1 (de) 2003-06-05
HK1077832A1 (en) 2006-02-24
TW200305426A (en) 2003-11-01
NO20044192L (no) 2004-10-04
RU2285009C2 (ru) 2006-10-10
CA2468412A1 (en) 2003-06-05
ZA200405029B (en) 2009-07-29
RU2004119437A (ru) 2005-07-10
AR037674A1 (es) 2004-12-01
WO2003045972A1 (de) 2003-06-05
NO20042694L (no) 2004-07-22
IL162200A (en) 2010-06-30
ES2307819T3 (es) 2008-12-01
JP2005513039A (ja) 2005-05-12
ZA200407868B (en) 2005-04-26
DK1448591T3 (da) 2008-09-29
BR0214469A (pt) 2004-10-13
CN1617879A (zh) 2005-05-18
NO326241B1 (no) 2008-10-27
HK1079215A1 (en) 2006-03-31
JP2005120110A (ja) 2005-05-12
KR100956912B1 (ko) 2010-05-11
US20060009436A1 (en) 2006-01-12
AU2002360949A1 (en) 2003-06-10
PE20030727A1 (es) 2003-09-18
UY27552A1 (es) 2003-06-30
US7018994B2 (en) 2006-03-28
JP2006306896A (ja) 2006-11-09
EP1448591B1 (de) 2008-05-21
CA2468412C (en) 2010-01-12
EP1916254A3 (de) 2012-11-14
US20030191099A1 (en) 2003-10-09
DE50212302D1 (de) 2008-07-03
EP1916254A2 (de) 2008-04-30
CY1108279T1 (el) 2014-02-12
JP4335820B2 (ja) 2009-09-30
PL207955B1 (pl) 2011-02-28
IL162200A0 (en) 2005-11-20
EP1448591A1 (de) 2004-08-25
US7538100B2 (en) 2009-05-26
RU2006120215A (ru) 2008-01-10
RU2339643C2 (ru) 2008-11-27
ATE396198T1 (de) 2008-06-15
MXPA04005015A (es) 2005-04-08
KR20040063158A (ko) 2004-07-12
CN100558741C (zh) 2009-11-11
TWI256891B (en) 2006-06-21

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