PL369669A1 - Sposób oczyszczania i/lub izolacji biologicznie czynnego czynnika stymulującego kolonie granulocytów - Google Patents

Sposób oczyszczania i/lub izolacji biologicznie czynnego czynnika stymulującego kolonie granulocytów

Info

Publication number
PL369669A1
PL369669A1 PL02369669A PL36966902A PL369669A1 PL 369669 A1 PL369669 A1 PL 369669A1 PL 02369669 A PL02369669 A PL 02369669A PL 36966902 A PL36966902 A PL 36966902A PL 369669 A1 PL369669 A1 PL 369669A1
Authority
PL
Poland
Prior art keywords
csf
biologically active
isolation
stimulating factor
colony stimulating
Prior art date
Application number
PL02369669A
Other languages
English (en)
Other versions
PL207775B1 (pl
Inventor
Porekar Vladka Gaberc
Viktor Menart
Original Assignee
Lek Pharmaceuticals D.D.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals D.D. filed Critical Lek Pharmaceuticals D.D.
Publication of PL369669A1 publication Critical patent/PL369669A1/pl
Publication of PL207775B1 publication Critical patent/PL207775B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
PL369669A 2001-12-19 2002-12-05 Sposób izolowania biologicznie czynnego poprawnie zwiniętego czynnika stymulującego kolonie granulocytów (G-CSF) PL207775B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI200100322A SI21102A (sl) 2001-12-19 2001-12-19 Postopek za izolacijo biološko aktivnega granulocitne kolonije stimulirajočega dejavnika
PCT/EP2002/013810 WO2003051922A1 (en) 2001-12-19 2002-12-05 Process for the purification and/or isolation of biologically active granulocyte colony stimulating factor

Publications (2)

Publication Number Publication Date
PL369669A1 true PL369669A1 (pl) 2005-05-02
PL207775B1 PL207775B1 (pl) 2011-01-31

Family

ID=20433022

Family Applications (1)

Application Number Title Priority Date Filing Date
PL369669A PL207775B1 (pl) 2001-12-19 2002-12-05 Sposób izolowania biologicznie czynnego poprawnie zwiniętego czynnika stymulującego kolonie granulocytów (G-CSF)

Country Status (21)

Country Link
US (1) US20050159589A1 (pl)
EP (2) EP2053061A1 (pl)
JP (1) JP4454311B2 (pl)
KR (1) KR20040071212A (pl)
CN (1) CN1606568A (pl)
AT (1) ATE423136T1 (pl)
AU (1) AU2002366275B2 (pl)
BR (1) BR0215191A (pl)
CA (1) CA2469984C (pl)
DE (1) DE60231243D1 (pl)
HR (1) HRP20040572A2 (pl)
HU (1) HUP0402547A3 (pl)
IL (2) IL162448A0 (pl)
MX (1) MXPA04006076A (pl)
NO (1) NO20042967L (pl)
NZ (1) NZ533305A (pl)
PL (1) PL207775B1 (pl)
RU (1) RU2358980C2 (pl)
SI (2) SI21102A (pl)
WO (1) WO2003051922A1 (pl)
ZA (1) ZA200404291B (pl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI21273A (sl) * 2002-07-31 2004-02-29 LEK farmacevtska dru�ba d.d. Priprava inkluzijskih teles z visokim deležem pravilno zvitega prekurzorja heterolognega proteina
DE60304435T2 (de) * 2004-01-19 2006-08-24 Ares Trading S.A. Verfahren zur Reinigung von in Bakterien exprimierten Proteinen
JP5031370B2 (ja) * 2004-09-17 2012-09-19 セルジェンテック株式会社 外用皮膚潰瘍治療剤
EP1856147A4 (en) * 2005-02-15 2008-07-02 Apollo Life Sciences Ltd MOLECULE AND CHIMESE MOLECULES THEREOF
EP1869078A2 (en) * 2005-03-17 2007-12-26 Zenotech Laboratories Limited Process for the purification of recombinant granulocyte-colony stimulating factor
DE102005033250A1 (de) 2005-07-15 2007-01-18 Bioceuticals Arzneimittel Ag Verfahren zur Reinigung von G-CSF
DE202006020194U1 (de) 2006-03-01 2007-12-06 Bioceuticals Arzneimittel Ag G-CSF-Flüssigformulierung
EP1878739A1 (en) 2006-07-14 2008-01-16 LEK Pharmaceuticals D.D. One step IMAC (MCAC) purification of proteins
WO2008096370A2 (en) * 2007-02-05 2008-08-14 Natco Pharma Limited An efficient and novel purification method of recombinant hg-csf
DK2197919T3 (da) 2007-08-27 2014-07-07 Ratiopharm Gmbh Flydende formulering af g-csf-konjugat
JP2009073819A (ja) * 2007-08-29 2009-04-09 Fujifilm Corp 生理活性物質の精製方法
WO2010146599A1 (en) * 2009-06-16 2010-12-23 Lupin Limited Process for purification of recombinant human granulocyte colony stimulating factor
KR101741859B1 (ko) 2009-06-22 2017-06-15 암젠 인크 화학적으로 조절된 산화환원 상태를 사용한 단백질의 재폴딩
SI3660032T1 (sl) 2009-06-25 2026-02-27 Amgen Inc. Postopki zajemanja in čiščenja beljakovin, izraženih v nesesalskem sistemu
WO2011121031A1 (en) * 2010-03-30 2011-10-06 Octapharma Ag Process for the purification of a growth factor protein
JP6147726B2 (ja) 2011-03-29 2017-06-14 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーＧｌａｘｏＳｍｉｔｈＫｌｉｎｅ ＬＬＣ タンパク質精製のためのバッファー系
CN103215340A (zh) * 2012-01-19 2013-07-24 江苏粒福特生物科技有限公司 一种新颖的粒细胞制备及其抗癌活性检测方法
HUP1200172A2 (en) * 2012-03-19 2013-10-28 Richter Gedeon Nyrt Methods for refolding g-csf from inclusion bodies
HUP1200171A1 (hu) 2012-03-19 2013-09-30 Richter Gedeon Nyrt Módszerek polipeptidek elõállítására

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61227526A (ja) 1984-07-25 1986-10-09 Chugai Pharmaceut Co Ltd 新規なコロニー刺激因子
DE3680613D1 (de) 1985-02-08 1991-09-05 Chugai Pharmaceutical Co Ltd Menschlicher granuloxcyt-kolonie-stimulierungsfaktor.
US4810643A (en) 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
DK203187A (da) 1986-04-22 1987-10-23 Immunex Corp Human g-csf proteinekspression
FI900178A0 (fi) * 1988-05-13 1990-01-12 Amgen Inc Kompositioner och foerfarande foer behandling eller foerhindrande av infektioner hos djur.
US5055555A (en) 1989-01-05 1991-10-08 Helmut Sassenfeld Purification of G-CSF
US5169936A (en) 1989-04-14 1992-12-08 Biogen, Inc. Protein purification on immobilized metal affinity resins effected by elution using a weak ligand
US5932102A (en) 1998-01-12 1999-08-03 Schering Corporation Immobilized metal, affinity chromatography
FR2796071B1 (fr) 1999-07-08 2001-09-07 Hoechst Marion Roussel Inc Procede de purification de facteur de stimulation de colonies de granulocytes

Also Published As

Publication number Publication date
AU2002366275A1 (en) 2003-06-30
MXPA04006076A (es) 2005-02-24
EP1458757B1 (en) 2009-02-18
RU2358980C2 (ru) 2009-06-20
IL162448A (en) 2010-12-30
SI21102A (sl) 2003-06-30
DE60231243D1 (de) 2009-04-02
AU2002366275B2 (en) 2009-04-02
CA2469984C (en) 2014-05-20
CN1606568A (zh) 2005-04-13
BR0215191A (pt) 2004-11-16
HRP20040572A2 (en) 2005-06-30
CA2469984A1 (en) 2003-06-26
HUP0402547A2 (hu) 2005-03-29
HK1064681A1 (en) 2005-02-04
NO20042967L (no) 2004-09-07
RU2004121982A (ru) 2005-04-20
NZ533305A (en) 2005-11-25
ATE423136T1 (de) 2009-03-15
EP1458757A1 (en) 2004-09-22
IL162448A0 (en) 2005-11-20
US20050159589A1 (en) 2005-07-21
ZA200404291B (en) 2005-08-05
EP2053061A1 (en) 2009-04-29
HUP0402547A3 (en) 2010-01-28
PL207775B1 (pl) 2011-01-31
WO2003051922A1 (en) 2003-06-26
JP2005525304A (ja) 2005-08-25
JP4454311B2 (ja) 2010-04-21
KR20040071212A (ko) 2004-08-11
SI1458757T1 (sl) 2009-10-31

Similar Documents

Publication Publication Date Title
HRP20040572A2 (en) Process for the purification and/or isolation of biologically active granulocyte colony stimulating factor
SI1492878T1 (sl) Postopek za pripravo Ĺľelenega profila gliko-izoform eritropoietina
KR960007612A (ko) 재조합 사람 혈청 알부민의 정제방법
ATE276994T1 (de) Verfahren zur reinigung von milchsäure auf industrieller basis
ATE403671T1 (de) Methoden zur aufreinigung von rekombinatem humanem erythropoietin aus zellkulturüberständen
DE58903791D1 (de) Peptidderivate, verfahren zu ihrer herstellung und ihre verwendung.
SK8592002A3 (en) Process for the purification of pharmacologically active proteins
CA2664855C (en) Organic-inorganic hybrid chiral sorbent and process for the preparation thereof
SI1753778T1 (sl) Postopek za čiščenje eritropoetina
DK1714982T3 (da) Fremgangsmåde til rensning af stærkt anioniske proteiner
IL175350A0 (en) Method for the production of statins
CA2210990A1 (en) New combined process for the purification of vancomycin hydrochloride
US4627919A (en) Resolving agent
Ogura et al. An efficient 1, 3-asymmetric induction accompanied with epimerization at the 2-position. Stereoselective reduction of α-substituted β-keto sulfoxides under basic conditions
DE3878577D1 (de) Verwendung von funktionellen polymerharzen als stationaere phase in der affinitaetschromatographie fuer die reinigung des wachstumsfaktors und entsprechendes reinigungsverfahren.
AU2003302418A1 (en) Method and apparatus for concentration and purification of nucleic acid
EP1148046A4 (en) PROCESS RELATING TO THE PREPARATION OF ALPHA-AMINOCETONES
EP1178114A3 (en) Heat-stable d-aminoacylase
IL182830A0 (en) Purification of recombinant human factor xiii
NO20052916L (no) Fremgangsmate for rensingen av TNF-bindende proteiner ved anvendelse av IMAC
AU2002366765A1 (en) Process for producing diene compound
Kim et al. Purification and Characterization of $\beta $-Xylosidase from Trichoderma sp. SY
AU2001287739A1 (en) Process for the purification of epi-hne proteins
KR960017519A (ko) 폐산을 이용한 고순도 염화제일철 수용액의 제조방법
CA2261144A1 (en) Improvements in the synthesis of annamycin