PL370161A1 - Rozpadająca się w jamie ustnej (orodyspergowalna)kompozycja farmaceutyczna zawierająca iwabradynę - Google Patents

Rozpadająca się w jamie ustnej (orodyspergowalna)kompozycja farmaceutyczna zawierająca iwabradynę

Info

Publication number: PL370161A1
Authority: PL; Poland
Prior art keywords: ivabradine; pharmaceutical composition; orodispersible pharmaceutical; orodispersible; composition
Prior art date: 2002-01-23

Application number

PL03370161A

Other languages

English (en)

Other versions

PL204938B1 (pl

Inventor

Patrick Wuthrich

Herve Rolland

Marc Julien

Original Assignee

Les Laboratoires Servier

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-23

Filing date

2003-01-22

Publication date

2005-05-16

2003-01-22 Application filed by Les Laboratoires Servier filed Critical Les Laboratoires Servier

2005-05-16 Publication of PL370161A1 publication Critical patent/PL370161A1/pl

2010-02-26 Publication of PL204938B1 publication Critical patent/PL204938B1/pl

Links

ACRHBAYQBXXRTO-OAQYLSRUSA-N ivabradine Chemical compound C1CC2=CC(OC)=C(OC)C=C2CC(=O)N1CCCN(C)C[C@H]1CC2=C1C=C(OC)C(OC)=C2 ACRHBAYQBXXRTO-OAQYLSRUSA-N 0.000 title 1
229960003825 ivabradine Drugs 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Physiology (AREA)
Zoology (AREA)
Nutrition Science (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)

PL370161A 2002-01-23 2003-01-22 Rozpadająca się w jamie ustnej (orodyspergowalna) kompozycja farmaceutyczna zawierająca iwabradynę PL204938B1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0200791A FR2834896B1 (fr)	2002-01-23	2002-01-23	Composition pharmaceutique orodispersible d'ivabradine

Publications (2)

Publication Number	Publication Date
PL370161A1 true PL370161A1 (pl)	2005-05-16
PL204938B1 PL204938B1 (pl)	2010-02-26

Family

ID=27589555

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL370161A PL204938B1 (pl)	2002-01-23	2003-01-22	Rozpadająca się w jamie ustnej (orodyspergowalna) kompozycja farmaceutyczna zawierająca iwabradynę

Country Status (27)

Country	Link
US (2)	US20050106238A1 (pl)
EP (1)	EP1474152B1 (pl)
JP (1)	JP4500052B2 (pl)
KR (1)	KR100613550B1 (pl)
CN (1)	CN1278688C (pl)
AR (1)	AR038206A1 (pl)
AT (1)	ATE348619T1 (pl)
AU (1)	AU2003215706B2 (pl)
BR (1)	BRPI0307056B1 (pl)
CA (1)	CA2473203C (pl)
CY (1)	CY1108854T1 (pl)
DE (1)	DE60310526T2 (pl)
DK (1)	DK1474152T3 (pl)
EA (1)	EA007681B1 (pl)
ES (1)	ES2278165T3 (pl)
FR (1)	FR2834896B1 (pl)
GE (1)	GEP20063820B (pl)
MA (1)	MA27102A1 (pl)
MX (1)	MXPA04007199A (pl)
NO (1)	NO333698B1 (pl)
NZ (1)	NZ533842A (pl)
PL (1)	PL204938B1 (pl)
PT (1)	PT1474152E (pl)
SI (1)	SI1474152T1 (pl)
UA (1)	UA78278C2 (pl)
WO (1)	WO2003061662A1 (pl)
ZA (1)	ZA200405129B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2868777B1 (fr) *	2004-04-13	2006-05-26	Servier Lab	Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
FR2882553B1 (fr) *	2005-02-28	2007-05-04	Servier Lab	Forme cristalline beta du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
US20090247572A1 (en) *	2005-08-23	2009-10-01	Koichi Wada	Agent for treating atrial fibrillation
FR2894825B1 (fr) *	2005-12-21	2010-12-03	Servier Lab	Nouvelle association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion et les compositions pharmaceutiques qui la contiennent
FR2911279B1 (fr) *	2007-01-11	2009-03-06	Servier Lab	Utilisation de l'ivabradine pour l'obtention de medicaments destines au traitement de la dysfonction endotheliale
WO2010128525A2 (en)	2009-05-04	2010-11-11	Dinesh Shantilal Patel	A formulation of ivabradine for treating the cardiovascular disease
US20130116239A1 (en)	2010-06-14	2013-05-09	ratiopharm GnbH	Ivabradine-containing pharmaceutical composition with modified release
CN103393611B (zh) *	2013-08-06	2015-08-19	南京正大天晴制药有限公司	一种盐酸伊伐布雷定片剂及其制备方法
WO2016102423A1 (en) *	2014-12-22	2016-06-30	Ratiopharm Gmbh	Composition comprising ivabradine in a dissolved form
GR1008821B (el)	2015-06-11	2016-08-01	Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων	Φαρμακευτικο σκευασμα που περιλαμβανει υδροχλωρικη ιβαμπραδινη και μεθοδος παρασκευης αυτου
CN106265582A (zh) *	2016-08-31	2017-01-04	辰欣药业股份有限公司	一种盐酸伊伐布雷定片及其制备工艺
EP3993773A1 (en) *	2019-07-01	2022-05-11	Orion Corporation	Methods for administering (r)-n-[4-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)phenyl]acetamide
JP7552146B2 (ja) *	2019-08-28	2024-09-18	小野薬品工業株式会社	イバブラジンを含有する錠剤

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT376147B (de) *	1980-12-15	1984-10-10	Gergely Gerhard	Verfahren und vorrichtung zum granulieren eines pulvergemisches
DE3505433A1 (de) *	1985-02-16	1986-08-21	Basf Ag, 6700 Ludwigshafen	Direkttablettierhilfsmittel
DE3506276C1 (de) *	1985-02-22	1986-04-24	Meggle Milchindustrie Gmbh & Co Kg, 8094 Reitmehring	Direkttablettiermittel
JP3253127B2 (ja) *	1991-06-07	2002-02-04	帝國製薬株式会社	生理活性ポリペプチド含有製剤
FR2681862B1 (fr) *	1991-09-27	1993-11-12	Adir Cie	Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent.
FR2710265B1 (fr) *	1993-09-22	1995-10-20	Adir	Composition pharmaceutique bioadhésive pour la libération contrôlée de principes actifs.
NZ278678A (en) *	1994-01-31	1998-03-25	Yamanouchi Pharma Co Ltd	Compressed moulded tablet with quick disintegration/dissolution in the mouth, mixture of low and high moldable saccharides as carriers
US6024981A (en) *	1997-04-16	2000-02-15	Cima Labs Inc.	Rapidly dissolving robust dosage form
JP2001526662A (ja) *	1997-05-09	2001-12-18	フェロンパテントリミテッド	舌下投与式タブレットの製造のための水溶液におけるインターフェロンの安定化
ATE219658T1 (de) *	1998-03-06	2002-07-15	Eurand Int	Schnell zerfallende tablette
JP2983973B1 (ja) *	1998-10-13	1999-11-29	大正薬品工業株式会社	口腔内速崩壊性固形製剤
JP2000273039A (ja) *	1999-01-20	2000-10-03	Taisho Pharmaceut Co Ltd	口腔内崩壊性組成物
JP2001058944A (ja) *	1999-06-18	2001-03-06	Takeda Chem Ind Ltd	速崩壊性固形製剤
EP1175899B1 (fr) *	2000-07-27	2007-08-29	Roquette FrÀ¨res	Granules à base d'amidon et de lactose
UA80393C2 (uk) *	2000-12-07	2007-09-25	Алтана Фарма Аг	Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
FR2818552B1 (fr) *	2000-12-26	2003-02-07	Servier Lab	Compositions pharmaceutique solide thermoformable pour la liberation controlee d'ivabradine
FR2834889B1 (fr) *	2002-01-18	2004-04-02	Roquette Freres	Forme pharmaceutique solide orodispersible

2002
- 2002-01-23 FR FR0200791A patent/FR2834896B1/fr not_active Expired - Fee Related
2003
- 2003-01-22 AR ARP030100177A patent/AR038206A1/es unknown
- 2003-01-22 DK DK03731734T patent/DK1474152T3/da active
- 2003-01-22 SI SI200330632T patent/SI1474152T1/sl unknown
- 2003-01-22 CA CA2473203A patent/CA2473203C/fr not_active Expired - Fee Related
- 2003-01-22 US US10/502,594 patent/US20050106238A1/en not_active Abandoned
- 2003-01-22 EP EP03731734A patent/EP1474152B1/fr not_active Expired - Lifetime
- 2003-01-22 GE GE5627A patent/GEP20063820B/en unknown
- 2003-01-22 JP JP2003561606A patent/JP4500052B2/ja not_active Expired - Fee Related
- 2003-01-22 AU AU2003215706A patent/AU2003215706B2/en not_active Ceased
- 2003-01-22 DE DE60310526T patent/DE60310526T2/de not_active Expired - Lifetime
- 2003-01-22 NZ NZ533842A patent/NZ533842A/en not_active IP Right Cessation
- 2003-01-22 AT AT03731734T patent/ATE348619T1/de active
- 2003-01-22 EA EA200400927A patent/EA007681B1/ru not_active IP Right Cessation
- 2003-01-22 PL PL370161A patent/PL204938B1/pl unknown
- 2003-01-22 BR BRPI0307056-5A patent/BRPI0307056B1/pt not_active IP Right Cessation
- 2003-01-22 MX MXPA04007199A patent/MXPA04007199A/es active IP Right Grant
- 2003-01-22 WO PCT/FR2003/000198 patent/WO2003061662A1/fr not_active Ceased
- 2003-01-22 KR KR1020047011350A patent/KR100613550B1/ko not_active Expired - Fee Related
- 2003-01-22 UA UA20040806963A patent/UA78278C2/uk unknown
- 2003-01-22 ES ES03731734T patent/ES2278165T3/es not_active Expired - Lifetime
- 2003-01-22 CN CNB038027119A patent/CN1278688C/zh not_active Expired - Fee Related
- 2003-01-22 PT PT03731734T patent/PT1474152E/pt unknown
2004
- 2004-06-28 ZA ZA2004/05129A patent/ZA200405129B/en unknown
- 2004-07-12 MA MA27776A patent/MA27102A1/fr unknown
- 2004-08-18 NO NO20043440A patent/NO333698B1/no not_active IP Right Cessation
2007
- 2007-01-16 CY CY20071100061T patent/CY1108854T1/el unknown
2010
- 2010-06-23 US US12/803,280 patent/US20100267693A1/en not_active Abandoned

Also Published As

Publication number	Publication date
JP2005523893A (ja)	2005-08-11
CN1278688C (zh)	2006-10-11
KR20040075366A (ko)	2004-08-27
DK1474152T3 (da)	2007-04-10
PL204938B1 (pl)	2010-02-26
FR2834896A1 (fr)	2003-07-25
EP1474152B1 (fr)	2006-12-20
NO20043440L (no)	2004-08-18
ES2278165T3 (es)	2007-08-01
EP1474152A1 (fr)	2004-11-10
DE60310526T2 (de)	2007-10-25
ATE348619T1 (de)	2007-01-15
AR038206A1 (es)	2005-01-05
ZA200405129B (en)	2005-08-31
AU2003215706B8 (en)	2003-09-02
BR0307056A (pt)	2004-10-26
HK1076741A1 (en)	2006-01-27
CY1108854T1 (el)	2014-07-02
KR100613550B1 (ko)	2006-08-16
PT1474152E (pt)	2007-02-28
MA27102A1 (fr)	2004-12-20
EA007681B1 (ru)	2006-12-29
JP4500052B2 (ja)	2010-07-14
DE60310526D1 (de)	2007-02-01
CA2473203A1 (fr)	2003-07-31
GEP20063820B (en)	2006-05-10
EA200400927A1 (ru)	2004-12-30
MXPA04007199A (es)	2004-10-29
AU2003215706B2 (en)	2007-08-02
CN1622809A (zh)	2005-06-01
SI1474152T1 (sl)	2007-04-30
NO333698B1 (no)	2013-08-26
UA78278C2 (en)	2007-03-15
BRPI0307056B1 (pt)	2015-06-30
WO2003061662A1 (fr)	2003-07-31
US20100267693A1 (en)	2010-10-21
NZ533842A (en)	2005-08-26
CA2473203C (fr)	2010-08-17
FR2834896B1 (fr)	2004-02-27
US20050106238A1 (en)	2005-05-19

Publication	Publication Date	Title
PL370160A1 (pl)	2005-05-16	Rozpadająca się w jamie ustnej (orodyspergowalna)kompozycja farmaceutyczna zawierająca agomelatynę
AU2003291103A8 (en)	2004-06-15	Pharmaceutical composition
EP1450824A4 (en)	2005-09-28	PHARMACEUTICAL COMPOSITION
AU2003220786A1 (en)	2003-09-18	Orodispersible pharmaceutical composition comprising agomelatine
IL164547A0 (en)	2005-12-18	Pharmaceutical composition
IL165878A0 (en)	2006-01-15	Pharmaceutical composition
HUP0303163A3 (en)	2008-03-28	Tramadol-based pharmaceutical composition
GB0117057D0 (en)	2001-09-05	Pharmaceutical composition
GB0129117D0 (en)	2002-01-23	Pharmaceutical composition
PL376840A1 (pl)	2006-01-09	Kompozycja farmaceutyczna o przedłużonym uwalnianiu
SI1474152T1 (sl)	2007-04-30	Orodisperzibilen farmacevtski sestavek ivabradina
AU2003215706A1 (en)	2003-09-18	Orodispersible pharmaceutical composition comprising ivabradine
PL370162A1 (pl)	2005-05-16	Rozpadająca się w jamie ustnej (orodyspergowalna)kompozycja farmaceutyczna zawierająca perindopril
AU2003215708A1 (en)	2003-09-18	Orodispersible pharmaceutical composition comprising perindopril
GB0116107D0 (en)	2001-08-22	Pharmaceutical composition
GB0127805D0 (en)	2002-01-09	Pharmaceutical composition
PL370037A1 (pl)	2005-05-16	Kompozycja farmaceutyczna
IL157411A0 (en)	2004-03-28	Pharmaceutical composition
GB0217703D0 (en)	2002-09-11	Pharmaceutical composition
SI1467750T1 (sl)	2006-10-31	Farmacevtski sestavek perindoprila disperzen v ustih (orodisperzen)
HU0103049D0 (en)	2001-10-28	Pharmaceutical composition
GB0125061D0 (en)	2001-12-12	Pharmaceutical composition
AU2003219238A1 (en)	2003-09-02	Orodispersible pharmaceutical composition comprising testosterone
GB0211355D0 (en)	2002-06-26	Pharmaceutical composition
GB0210905D0 (en)	2002-06-19	Pharmaceutical composition