PL370479A1 - Związki heksacykliczne - Google Patents

Związki heksacykliczne

Info

Publication number
PL370479A1
PL370479A1 PL02370479A PL37047902A PL370479A1 PL 370479 A1 PL370479 A1 PL 370479A1 PL 02370479 A PL02370479 A PL 02370479A PL 37047902 A PL37047902 A PL 37047902A PL 370479 A1 PL370479 A1 PL 370479A1
Authority
PL
Poland
Prior art keywords
sup
compounds
hexacyclic compounds
hexacyclic
identified
Prior art date
Application number
PL02370479A
Other languages
English (en)
Other versions
PL207510B1 (pl
Inventor
Takeshi Murata
Satoshi Niizuma
Nobuo Shimma
Hitomi Suda
Masao Tsukazaki
Original Assignee
Chugai Seiyaku Kabushiki Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Seiyaku Kabushiki Kaisha filed Critical Chugai Seiyaku Kabushiki Kaisha
Publication of PL370479A1 publication Critical patent/PL370479A1/pl
Publication of PL207510B1 publication Critical patent/PL207510B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL370479A 2001-11-30 2002-11-25 Związki heksacykliczne, kompozycje je zawierające oraz ich zastosowanie PL207510B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01128361 2001-11-30

Publications (2)

Publication Number Publication Date
PL370479A1 true PL370479A1 (pl) 2005-05-30
PL207510B1 PL207510B1 (pl) 2010-12-31

Family

ID=8179394

Family Applications (1)

Application Number Title Priority Date Filing Date
PL370479A PL207510B1 (pl) 2001-11-30 2002-11-25 Związki heksacykliczne, kompozycje je zawierające oraz ich zastosowanie

Country Status (28)

Country Link
US (2) US6825194B2 (pl)
EP (1) EP1480984B9 (pl)
JP (1) JP4305909B2 (pl)
KR (1) KR100895746B1 (pl)
CN (1) CN100338066C (pl)
AT (1) ATE398131T1 (pl)
AU (1) AU2002356720B2 (pl)
BR (1) BR0214615A (pl)
CA (1) CA2468824C (pl)
DE (1) DE60227113D1 (pl)
ES (1) ES2307830T3 (pl)
GT (1) GT200200250A (pl)
HU (1) HUP0500062A3 (pl)
IL (1) IL162058A0 (pl)
MX (1) MXPA04005185A (pl)
MY (1) MY136138A (pl)
NO (1) NO329005B1 (pl)
NZ (1) NZ533568A (pl)
PA (1) PA8558901A1 (pl)
PE (1) PE20030725A1 (pl)
PL (1) PL207510B1 (pl)
RS (1) RS51051B (pl)
RU (1) RU2299212C2 (pl)
TW (1) TWI258481B (pl)
UA (1) UA80409C2 (pl)
UY (1) UY27560A1 (pl)
WO (1) WO2003045952A2 (pl)
ZA (1) ZA200404522B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004073601A2 (en) * 2003-02-21 2004-09-02 Chugai Seiyaku Kabushiki Kaisha Process for the preparation of hexacyclic camptothecin derivatives
US7910593B2 (en) 2004-04-09 2011-03-22 Chugai Seiyaku Kabushiki Kaisha Water-soluble prodrugs
TW200744603A (en) 2005-08-22 2007-12-16 Chugai Pharmaceutical Co Ltd Novel anticancer concomitant drug
US20090118271A1 (en) * 2005-10-19 2009-05-07 Chugai Seiyaku Kabushiki Kaisha Preventive or Therapeutic Agents for Pancreatic Cancer, Ovarian Cancer, or Liver Cancer Comprising a Novel Water-Soluble Prodrug
RU2439073C1 (ru) * 2010-07-13 2012-01-10 Государственное образовательное учреждение высшего профессионального образования "Кубанский государственный технологический университет" (ГОУ ВПО "КубГТУ") СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ ИНДОЛИЗИНО[7,6-b]ИНДОЛА
KR20240104214A (ko) 2019-03-29 2024-07-04 메디뮨 리미티드 화합물 및 이의 접합체

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4473692A (en) 1981-09-04 1984-09-25 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
US4939255A (en) * 1987-06-24 1990-07-03 Daiichi Pharmaceutical Co., Ltd. Hexa-cyclic camptothecin derivatives
HU213136B (en) * 1990-08-14 1997-02-28 Kyorin Seiyaku Kk Process for producing fluoroethyl camptothecin derivatives and pharmaceutical compositions containing them
JP3008226B2 (ja) * 1991-01-16 2000-02-14 第一製薬株式会社 六環性化合物
JP3359955B2 (ja) * 1992-07-16 2002-12-24 第一製薬株式会社 抗腫瘍剤
GB9402934D0 (en) * 1994-02-16 1994-04-06 Erba Carlo Spa Camptothecin derivatives and process for their preparation
US5663177A (en) * 1995-05-31 1997-09-02 Smithkline Beecham Corporation Water soluble camptothecin analogs
DE69834923T2 (de) 1997-02-14 2006-10-19 Bionumerik Pharmaceuticals, Inc., San Antonio Hochgradig lipophile camptothecin-derivate
GB9715821D0 (en) * 1997-07-25 1997-10-01 Pharmacia & Upjohn Spa Amidino-camptothecin derivatives

Also Published As

Publication number Publication date
KR100895746B1 (ko) 2009-04-30
MXPA04005185A (es) 2004-08-11
AU2002356720A1 (en) 2003-06-10
RU2004119841A (ru) 2005-03-27
ATE398131T1 (de) 2008-07-15
HUP0500062A3 (en) 2012-12-28
IL162058A0 (en) 2005-11-20
PA8558901A1 (es) 2003-06-30
NO20042729L (no) 2004-08-27
US6825194B2 (en) 2004-11-30
EP1480984B9 (en) 2009-03-11
RU2299212C2 (ru) 2007-05-20
JP2005511643A (ja) 2005-04-28
HK1077303A1 (en) 2006-02-10
TWI258481B (en) 2006-07-21
UY27560A1 (es) 2003-05-30
US20030144304A1 (en) 2003-07-31
ZA200404522B (en) 2005-01-04
MY136138A (en) 2008-08-29
CN100338066C (zh) 2007-09-19
PE20030725A1 (es) 2003-08-28
NO329005B1 (no) 2010-07-19
UA80409C2 (en) 2007-09-25
WO2003045952A3 (en) 2003-10-16
GT200200250A (es) 2004-01-15
PL207510B1 (pl) 2010-12-31
AU2002356720B2 (en) 2009-01-29
US20050059679A1 (en) 2005-03-17
ES2307830T3 (es) 2008-12-01
RS47004A (sr) 2007-02-05
TW200408642A (en) 2004-06-01
DE60227113D1 (de) 2008-07-24
CA2468824C (en) 2011-01-11
JP4305909B2 (ja) 2009-07-29
WO2003045952A2 (en) 2003-06-05
RS51051B (sr) 2010-10-31
KR20040062976A (ko) 2004-07-09
US7109195B2 (en) 2006-09-19
HUP0500062A2 (hu) 2005-04-28
EP1480984B1 (en) 2008-06-11
BR0214615A (pt) 2004-09-14
CN1617874A (zh) 2005-05-18
CA2468824A1 (en) 2003-06-05
HK1072935A1 (en) 2005-09-16
NZ533568A (en) 2006-01-27
EP1480984A2 (en) 2004-12-01

Similar Documents

Publication Publication Date Title
MY135841A (en) Novel benzodioxoles
JO2311B1 (en) Alkyl inhibitors Ariel phosphodiesterase-4
AP2002002637A0 (en) Novel piperazine
WO2004020431A3 (en) Novel benzoimidazole derivatives useful as antiproliferative agents
AU2002319814A1 (en) Substituted 1h-dihydropyrazoles, their preparation and use
HRP20031003A2 (en) 4'-substituted nukleosides
BG106003A (en) New n-cyanomethylamides and compositions as protease inhibitors
BG106586A (en) Pyrazolopyramidines as therapeutic agents
BG108268A (en) Pyrazolopyrimidines as therapeutic agents
JO2282B1 (en) Oxazole derivatives
AU2003228674A1 (en) Muscarinic antagonists
MXPA03010142A (es) Nuevos derivados de arilheteroalquilamina.
SE9803518D0 (sv) Novel compounds
GEP20105095B (en) Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents
DE69907419D1 (en) Antitumorwirkstoffe
MXPA04006041A (es) Antivirales de piridoquinoxalina.
AP2001002191A0 (en) 3,3- Biarylpiperine and 2,2-biarylmorpholine derivatives.
SE0203070D0 (en) Novel compounds
SE0302756D0 (sv) Novel Compounds
AP2001002306A0 (en) Bridged piperazine derivatives.
AU2001290480A1 (en) Cyclized benzamide neurokinin antagonists for use in therapy
SE9803773D0 (sv) Compounds
CA2356985A1 (en) 5ht1 antagonists for antidepressant therapy
IL162058A0 (en) Hexacyclic compounds
YU46302A (sh) Supstituisani piroli

Legal Events

Date Code Title Description
RECP Rectifications of patent specification
LAPS Decisions on the lapse of the protection rights

Effective date: 20121125