PL370779A1 - Pochodne skrobi, koniugaty skrobia/substancja czynna, sposób ich wytwarzania oraz ich zastosowanie jako leki - Google Patents

Pochodne skrobi, koniugaty skrobia/substancja czynna, sposób ich wytwarzania oraz ich zastosowanie jako leki

Info

Publication number
PL370779A1
PL370779A1 PL03370779A PL37077903A PL370779A1 PL 370779 A1 PL370779 A1 PL 370779A1 PL 03370779 A PL03370779 A PL 03370779A PL 37077903 A PL37077903 A PL 37077903A PL 370779 A1 PL370779 A1 PL 370779A1
Authority
PL
Poland
Prior art keywords
starch
medicaments
production
derivatives
residue
Prior art date
Application number
PL03370779A
Other languages
English (en)
Inventor
Klaus Sommermeyer
Norbert Zander
Ronald Frank
Harald Conradt
Original Assignee
Fresenius Kabi Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Kabi Deutschland Gmbh filed Critical Fresenius Kabi Deutschland Gmbh
Publication of PL370779A1 publication Critical patent/PL370779A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00Preparation of derivatives of starch
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL03370779A 2002-02-20 2003-02-20 Pochodne skrobi, koniugaty skrobia/substancja czynna, sposób ich wytwarzania oraz ich zastosowanie jako leki PL370779A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10207072A DE10207072A1 (de) 2002-02-20 2002-02-20 Stärkederivate, ihre Konjugate und Verfahren zur Herstellung derselben

Publications (1)

Publication Number Publication Date
PL370779A1 true PL370779A1 (pl) 2005-05-30

Family

ID=27635176

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03370779A PL370779A1 (pl) 2002-02-20 2003-02-20 Pochodne skrobi, koniugaty skrobia/substancja czynna, sposób ich wytwarzania oraz ich zastosowanie jako leki

Country Status (13)

Country Link
US (1) US7285661B2 (pl)
EP (1) EP1476470B1 (pl)
JP (1) JP2005529192A (pl)
CN (1) CN1625569A (pl)
AT (1) ATE370974T1 (pl)
AU (1) AU2003212255B2 (pl)
CA (1) CA2473068C (pl)
DE (2) DE10207072A1 (pl)
DK (1) DK1476470T3 (pl)
ES (1) ES2289262T3 (pl)
MX (1) MXPA04007068A (pl)
PL (1) PL370779A1 (pl)
WO (1) WO2003070772A1 (pl)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10112825A1 (de) * 2001-03-16 2002-10-02 Fresenius Kabi De Gmbh HESylierung von Wirkstoffen in wässriger Lösung
DE10209821A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung von Proteinen an ein modifiziertes Polysaccharid
DE10209822A1 (de) * 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
BR0314227A (pt) * 2002-09-11 2005-10-25 Fresenius Kabi De Gmbh Derivados de amido de hidroxialquila
US7538092B2 (en) 2002-10-08 2009-05-26 Fresenius Kabi Deutschland Gmbh Pharmaceutically active oligosaccharide conjugates
EP1473308A1 (de) * 2003-04-28 2004-11-03 B. Braun Melsungen Ag Stärkederivate zur klinischen, insbesondere parenteralen Anwendung
BRPI0412671A (pt) * 2003-08-08 2006-10-03 Fresenius Kabi De Gmbh conjugados de um polìmero e uma proteìna ligados por um grupo de ligação de oxima
WO2005014655A2 (en) * 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
PL1660134T3 (pl) * 2003-08-08 2011-05-31 Fresenius Kabi Deutschland Gmbh Koniugaty hydroksyalkiloskrobi i G-CSF
CA2555467C (en) * 2004-02-09 2012-10-09 Noxxon Pharma Ag Process for the production of conjugates from polysaccharides and polynucleotides
AU2005217157B2 (en) 2004-03-01 2011-05-12 B. Braun Melsungen Ag Hydroxyethyl starch
JP5191729B2 (ja) 2004-03-11 2013-05-08 フレゼニウス・カビ・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 還元的アミノ化によって製造される、ヒドロキシアルキルデンプンとタンパク質とのコンジュゲート
ES2390885T3 (es) * 2004-03-11 2012-11-19 Fresenius Kabi Deutschland Gmbh Conjugados de hidroxialquilalmidón y una proteína
CN101137396A (zh) * 2005-03-11 2008-03-05 弗雷泽纽斯卡比德国有限公司 由无活性初始材料制备生物活性糖蛋白
CN102159230A (zh) 2008-07-23 2011-08-17 Ambrx公司 经修饰的牛g-csf多肽和其用途
BR112012015597A2 (pt) 2009-12-21 2017-01-31 Ambrx Inc peptídeos de somatotropina suínos modificados e seus usos
MX349301B (es) 2009-12-21 2017-07-21 Ambrx Inc Polipéptidos de somatotropina bovina modificados y sus usos.
TWI480288B (zh) 2010-09-23 2015-04-11 Lilly Co Eli 牛顆粒細胞群落刺激因子及其變體之調配物
RU2014103288A (ru) 2011-07-01 2015-08-10 Байер Интеллектчуал Проперти Гмбх Слитые полипептиды релаксина и их применение
CN102321185B (zh) * 2011-08-09 2012-12-19 武汉华科大生命科技有限公司 一种中分子量羟乙基淀粉的合成方法
WO2015132724A1 (en) 2014-03-05 2015-09-11 Pfizer Inc. Improved muteins of clotting factor viii
WO2024241086A1 (en) 2023-05-24 2024-11-28 Ambrx, Inc. Pegylated bovine interferon lambda and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2600897A1 (fr) * 1986-07-04 1988-01-08 Pf Medicament Pansement proteolytique et absorbant et procede pour sa preparation
DE19628705A1 (de) * 1996-07-08 1998-01-15 Fresenius Ag Neue Sauerstoff-Transport-Mittel, diese enthaltende Hämoglobin-Hydroxyethylstärke-Konjugate, Verfahren zu deren Herstellung, sowie deren Verwendung als Blutersatzstoffe
DE10135694A1 (de) * 2001-07-21 2003-02-06 Supramol Parenteral Colloids Amphiphile Stärke-und Hydroxyethylstärke-Konjugate

Also Published As

Publication number Publication date
JP2005529192A (ja) 2005-09-29
ES2289262T3 (es) 2008-02-01
CN1625569A (zh) 2005-06-08
ATE370974T1 (de) 2007-09-15
WO2003070772A1 (de) 2003-08-28
DE50308003D1 (de) 2007-10-04
DE10207072A1 (de) 2003-08-28
MXPA04007068A (es) 2004-11-01
EP1476470A1 (de) 2004-11-17
US20050065113A1 (en) 2005-03-24
DK1476470T3 (da) 2007-11-12
US7285661B2 (en) 2007-10-23
CA2473068A1 (en) 2003-08-28
AU2003212255B2 (en) 2009-01-22
EP1476470B1 (de) 2007-08-22
CA2473068C (en) 2011-06-07
AU2003212255A1 (en) 2003-09-09

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)