PL373420A1 - Środki sedacyjno-nasenne o krótkotrwałym działaniu do anestezji i sedacji - Google Patents

Środki sedacyjno-nasenne o krótkotrwałym działaniu do anestezji i sedacji

Info

Publication number
PL373420A1
PL373420A1 PL03373420A PL37342003A PL373420A1 PL 373420 A1 PL373420 A1 PL 373420A1 PL 03373420 A PL03373420 A PL 03373420A PL 37342003 A PL37342003 A PL 37342003A PL 373420 A1 PL373420 A1 PL 373420A1
Authority
PL
Poland
Prior art keywords
sedation
anesthesia
short
hypnotic agents
sedative hypnotic
Prior art date
Application number
PL03373420A
Other languages
English (en)
Other versions
PL207038B1 (pl
Inventor
Thomas E. Jenkins
Sabine Axt
Jennifer Bolton
Original Assignee
Theravance, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance, Inc. filed Critical Theravance, Inc.
Publication of PL373420A1 publication Critical patent/PL373420A1/pl
Publication of PL207038B1 publication Critical patent/PL207038B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/14—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
    • C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL373420A 2002-01-25 2003-01-24 Podstawione pochodne kwasu fenylooctowego, związek pośredni, kompozycja farmaceutyczna zawierająca te pochodne oraz ich zastosowanie PL207038B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35138502P 2002-01-25 2002-01-25
US37921902P 2002-05-09 2002-05-09

Publications (2)

Publication Number Publication Date
PL373420A1 true PL373420A1 (pl) 2005-08-22
PL207038B1 PL207038B1 (pl) 2010-10-29

Family

ID=32179539

Family Applications (1)

Application Number Title Priority Date Filing Date
PL373420A PL207038B1 (pl) 2002-01-25 2003-01-24 Podstawione pochodne kwasu fenylooctowego, związek pośredni, kompozycja farmaceutyczna zawierająca te pochodne oraz ich zastosowanie

Country Status (21)

Country Link
US (4) US6887866B2 (pl)
EP (1) EP1509492B1 (pl)
KR (2) KR100925790B1 (pl)
CN (1) CN1257152C (pl)
AT (1) ATE522498T1 (pl)
AU (1) AU2003299453B2 (pl)
BR (1) BRPI0307017B1 (pl)
CA (1) CA2474262C (pl)
CY (1) CY1112487T1 (pl)
DK (1) DK1509492T3 (pl)
ES (1) ES2371461T3 (pl)
IL (3) IL162862A0 (pl)
MX (1) MXPA04007023A (pl)
NZ (1) NZ534012A (pl)
PL (1) PL207038B1 (pl)
PT (1) PT1509492E (pl)
RU (1) RU2315037C2 (pl)
SI (1) SI1509492T1 (pl)
TW (1) TWI290466B (pl)
WO (1) WO2004037750A2 (pl)
ZA (1) ZA200405561B (pl)

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US6887866B2 (en) 2002-01-25 2005-05-03 Theravance, Inc. Short-acting sedative hypnotic agents for anesthesia and sedation
WO2005009420A2 (en) * 2003-07-23 2005-02-03 Theravance, Inc. Pharmaceutical compositions of short-acting sedative hypnotic agent
US8329744B2 (en) * 2005-11-02 2012-12-11 Relmada Therapeutics, Inc. Methods of preventing the serotonin syndrome and compositions for use thereof
US20090082466A1 (en) * 2006-01-27 2009-03-26 Najib Babul Abuse Resistant and Extended Release Formulations and Method of Use Thereof
WO2008134071A1 (en) * 2007-04-26 2008-11-06 Theraquest Biosciences, Inc. Multimodal abuse resistant extended release formulations
US20090286832A1 (en) * 2008-05-15 2009-11-19 Kiichiro Nabeta Narcotic emulsion formulations for treatment of surgical pain
EP2456868A4 (en) 2009-07-22 2013-11-06 Puretech Ventures METHOD AND COMPOSITIONS FOR TREATING SUFFERING OF SUFFERING THROUGH MUSCARIN RECEPTOR ACTIVATION
CN102190580A (zh) * 2010-03-12 2011-09-21 重庆欣欣向荣精细化工有限公司 乙基香兰素合成中间体3-乙氧基-4-羟基扁桃酸的制备方法
WO2011149412A1 (en) * 2010-05-13 2011-12-01 Astrazeneca Ab Injectable emulsion of sedative hypnotic agent
CN102863353A (zh) * 2012-07-27 2013-01-09 华中科技大学 取代的苯基乙酸酯化合物及其应用
CN103450009B (zh) * 2013-09-02 2015-04-22 江苏宝众宝达药业有限公司 一种对羟基苯乙酸的制备方法
CN105272871B (zh) * 2014-06-20 2017-08-22 济南蓝丹医药科技有限公司 具有提高的药代动力学性能和麻醉性能的苯基乙酸酯类化合物
CN104211615B (zh) * 2014-08-12 2017-11-03 武汉珈瑜科技有限公司 苯基氟取代的苯乙酸酯化合物及其应用
CN104262292B (zh) * 2014-09-08 2019-02-22 武汉珈瑜科技有限公司 苯乙酸酯化合物及其应用
CN104622806B (zh) * 2015-02-04 2018-03-16 北京蓝丹医药科技有限公司 一种丙泮尼地药物组合物及其制备方法
CN104887628A (zh) * 2015-06-02 2015-09-09 北京蓝丹医药科技有限公司 一种稳定的苯基乙酸酯类药物脂肪乳
CN104887629A (zh) * 2015-06-09 2015-09-09 北京蓝丹医药科技有限公司 一种稳定的丙泮尼地脂肪乳
UA128017C2 (uk) * 2018-09-28 2024-03-13 Каруна Тереп'Ютікс, Інк. Композиція і спосіб лікування розладу, що послаблюється активацією мускаринових рецепторів (варіанти)
WO2021219192A1 (en) 2020-04-27 2021-11-04 Symrise Ag Method for producing esters of homovanillic acid

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Also Published As

Publication number Publication date
CA2474262C (en) 2011-03-15
US7015346B2 (en) 2006-03-21
BR0307017A (pt) 2006-04-11
US6887866B2 (en) 2005-05-03
WO2004037750A3 (en) 2005-01-06
TWI290466B (en) 2007-12-01
KR20080070087A (ko) 2008-07-29
RU2315037C2 (ru) 2008-01-20
NZ534012A (en) 2006-12-22
IL162862A (en) 2011-04-28
US7514425B2 (en) 2009-04-07
EP1509492A2 (en) 2005-03-02
EP1509492B1 (en) 2011-08-31
KR100925790B1 (ko) 2009-11-11
IL201639A (en) 2011-12-29
US20060116424A1 (en) 2006-06-01
ES2371461T3 (es) 2012-01-03
RU2004125854A (ru) 2005-05-20
KR100951846B1 (ko) 2010-04-12
US20030153554A1 (en) 2003-08-14
MXPA04007023A (es) 2004-10-14
ZA200405561B (en) 2005-10-26
HK1075039A1 (en) 2005-12-02
BRPI0307017B1 (pt) 2015-11-10
DK1509492T3 (da) 2011-11-28
CN1257152C (zh) 2006-05-24
CN1622934A (zh) 2005-06-01
ATE522498T1 (de) 2011-09-15
PT1509492E (pt) 2011-11-21
US20050113364A1 (en) 2005-05-26
PL207038B1 (pl) 2010-10-29
AU2003299453B2 (en) 2007-11-29
WO2004037750A2 (en) 2004-05-06
US7939689B2 (en) 2011-05-10
TW200425896A (en) 2004-12-01
IL162862A0 (en) 2005-11-20
US20090253787A1 (en) 2009-10-08
AU2003299453A1 (en) 2004-05-13
SI1509492T1 (sl) 2012-03-30
KR20040093693A (ko) 2004-11-08
CY1112487T1 (el) 2015-12-09
CA2474262A1 (en) 2004-05-06

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