PL376525A1 - Sposób modyfikacji pokroju kryształów substancji leczniczej - Google Patents

Sposób modyfikacji pokroju kryształów substancji leczniczej

Info

Publication number
PL376525A1
PL376525A1 PL376525A PL37652504A PL376525A1 PL 376525 A1 PL376525 A1 PL 376525A1 PL 376525 A PL376525 A PL 376525A PL 37652504 A PL37652504 A PL 37652504A PL 376525 A1 PL376525 A1 PL 376525A1
Authority
PL
Poland
Prior art keywords
crystal formation
drug crystal
modifying drug
modifying
formation
Prior art date
Application number
PL376525A
Other languages
English (en)
Inventor
Sabine Pfeffer
Dierk Wieckhusen
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9951448&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL376525(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL376525A1 publication Critical patent/PL376525A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
PL376525A 2003-01-20 2004-01-19 Sposób modyfikacji pokroju kryształów substancji leczniczej PL376525A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0301259.8A GB0301259D0 (en) 2003-01-20 2003-01-20 Organic compounds

Publications (1)

Publication Number Publication Date
PL376525A1 true PL376525A1 (pl) 2006-01-09

Family

ID=9951448

Family Applications (2)

Application Number Title Priority Date Filing Date
PL376525A PL376525A1 (pl) 2003-01-20 2004-01-19 Sposób modyfikacji pokroju kryształów substancji leczniczej
PL393385A PL213192B1 (pl) 2003-01-20 2004-01-19 Sposób modyfikacji pokroju krysztalów substancji leczniczej, krysztaly mykofenolanu sodu i ich zastosowanie oraz kompozycja farmaceutyczna

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL393385A PL213192B1 (pl) 2003-01-20 2004-01-19 Sposób modyfikacji pokroju krysztalów substancji leczniczej, krysztaly mykofenolanu sodu i ich zastosowanie oraz kompozycja farmaceutyczna

Country Status (31)

Country Link
US (3) US20060122265A1 (pl)
EP (2) EP2308471A1 (pl)
JP (1) JP4549976B2 (pl)
KR (5) KR20100120321A (pl)
CN (2) CN101333201A (pl)
AR (2) AR043343A1 (pl)
AT (1) ATE546132T1 (pl)
AU (1) AU2004206731B2 (pl)
BR (1) BRPI0406827A (pl)
CA (2) CA2706900A1 (pl)
CL (1) CL2004000073A1 (pl)
CO (1) CO5580738A2 (pl)
CY (1) CY1112772T1 (pl)
DK (1) DK1592401T3 (pl)
EC (1) ECSP055918A (pl)
ES (1) ES2382035T3 (pl)
GB (1) GB0301259D0 (pl)
IL (1) IL169484A (pl)
MX (1) MXPA05007691A (pl)
MY (1) MY148297A (pl)
NO (1) NO20053846L (pl)
NZ (1) NZ541073A (pl)
PE (2) PE20110276A1 (pl)
PL (2) PL376525A1 (pl)
PT (1) PT1592401E (pl)
RU (1) RU2388757C2 (pl)
SG (1) SG155046A1 (pl)
SI (1) SI1592401T1 (pl)
TW (1) TWI325785B (pl)
WO (1) WO2004064806A2 (pl)
ZA (1) ZA200504442B (pl)

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GB0124953D0 (en) 2001-10-17 2001-12-05 Novartis Ag Organic Compounds
GB0301259D0 (en) 2003-01-20 2003-02-19 Novartis Ag Organic compounds
AR045957A1 (es) * 2003-10-03 2005-11-16 Novartis Ag Composicion farmaceutica y combinacion
WO2005105768A2 (en) 2004-04-26 2005-11-10 Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg Process for preparation of mycophenolic acid and ester derivatives thereof
MXPA06005658A (es) 2004-04-27 2007-04-10 Teva Gyogyszergyar Zartkoruen Proceso para preparacion de micofenolato mofetil, y otros esteres de acido micofenolico.
TWI322147B (en) 2004-07-20 2010-03-21 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Crystalline mycophenolate sodium
GB0419355D0 (en) * 2004-08-31 2004-09-29 Novartis Ag Organic compounds
US20080176937A1 (en) * 2007-01-23 2008-07-24 Apotex Fermentation Inc. Novel crystalline mycophenolate sodium polymorph and processes to manufacture same
PL2349220T3 (pl) * 2008-10-09 2012-12-31 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Zastosowanie rozpuszczalników organicznych w granulacji na mokro moksyfloksacyny
CN101756958B (zh) * 2008-11-10 2011-07-20 鲁南制药集团股份有限公司 一种治疗关节炎的药物组合物及其制备方法
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
JP5658751B2 (ja) 2009-07-10 2015-01-28 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプＪａｎｓｓｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａ Ｎａａｍｌｏｚｅ Ｖｅｎｎｏｏｔｓｃｈａｐ １−（β−Ｄ−グルコピラノシル）−４−メチル−３−［５−（４−フルオロフェニル）−２−チエニルメチル］ベンゼンのための結晶化方法
EA201270544A1 (ru) * 2009-10-13 2012-09-28 Тева Фармасьютикал Индастриз Лтд. Композиции с отсроченным высвобождением
EP2528894A1 (en) 2010-01-27 2012-12-05 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
NZ703128A (en) 2010-05-11 2016-04-29 Janssen Pharmaceutica Nv Pharmaceutical formulations comprising 1 - (beta-d-glucopyranosyl) - 2 -thienylmethylbenzene derivatives as inhibitors of sglt
CN103880800A (zh) * 2010-11-16 2014-06-25 北京京卫信康医药科技发展有限公司 麦考酚酸钠的新晶型及其制备方法
CN103880799A (zh) * 2010-11-16 2014-06-25 北京京卫信康医药科技发展有限公司 麦考酚酸钠的新晶型及其制备方法
WO2012140120A1 (en) 2011-04-13 2012-10-18 Janssen Pharmaceutica Nv Process for the preparation of compounds useful as inhibitors of sglt2
TWI582078B (zh) * 2013-01-23 2017-05-11 北京貝美拓新藥研發有限公司 抑制脯氨酸羥化酶活性的化合物的晶型及其應用
JP6838744B2 (ja) 2015-06-22 2021-03-03 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１Ｐ１レセプター関連障害における使用のための（Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸（化合物１）の結晶性Ｌ−アルギニン塩
US20170071970A1 (en) 2015-09-15 2017-03-16 Janssen Pharmaceutica Nv Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
LT3394051T (lt) * 2015-12-21 2020-08-10 Janssen Pharmaceutica N.V. Kristalizacijos procedūra, skirta kanagliflozino hemihidrato kristalų gavimui
CN110520124A (zh) 2017-02-16 2019-11-29 艾尼纳制药公司 用于治疗原发性胆汁性胆管炎的化合物和方法
KR20190113955A (ko) 2017-02-16 2019-10-08 아레나 파마슈티칼스, 인크. 장-외 증상을 갖는 염증성 장질환의 치료를 위한 화합물 및 방법
CN108727317A (zh) * 2017-04-25 2018-11-02 鲁南制药集团股份有限公司 一种麦考酚酸的晶型物
CN108727318A (zh) * 2017-04-25 2018-11-02 鲁南制药集团股份有限公司 麦考酚酸的晶型物
JP7397011B2 (ja) 2018-06-06 2023-12-12 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１ｐ１受容体に関連する状態を治療する方法
CN110922371B (zh) * 2019-12-27 2020-08-11 广东蓝宝制药有限公司 一种m2晶型麦考酚钠的制备方法
CN120168469A (zh) 2020-05-18 2025-06-20 诺华股份有限公司 Lnp023的结晶形式
US20250296904A1 (en) * 2022-05-31 2025-09-25 Honshu Chemical Industry Co., Ltd. Crystal of 4,4'-bis(1,1-bis(4-hydroxy-3-methylphenyl)ethyl)biphenyl and method for producing the same

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Also Published As

Publication number Publication date
HK1084874A1 (en) 2006-08-11
ES2382035T3 (es) 2012-06-04
BRPI0406827A (pt) 2005-12-27
KR100855149B1 (ko) 2008-08-28
CN100595199C (zh) 2010-03-24
CN101333201A (zh) 2008-12-31
US8124795B2 (en) 2012-02-28
NO20053846L (no) 2005-08-16
US20110288313A1 (en) 2011-11-24
CO5580738A2 (es) 2005-11-30
GB0301259D0 (en) 2003-02-19
SI1592401T1 (sl) 2012-05-31
PT1592401E (pt) 2012-05-10
TWI325785B (en) 2010-06-11
MXPA05007691A (es) 2005-09-30
ZA200504442B (en) 2006-02-22
EP1592401A2 (en) 2005-11-09
CY1112772T1 (el) 2016-02-10
PE20110276A1 (es) 2011-05-27
CN1738605A (zh) 2006-02-22
MY148297A (en) 2013-03-29
AR103711A2 (es) 2017-05-31
WO2004064806A3 (en) 2004-10-28
CL2004000073A1 (es) 2005-01-14
RU2388757C2 (ru) 2010-05-10
JP4549976B2 (ja) 2010-09-22
AU2004206731A8 (en) 2004-08-05
JP2006515016A (ja) 2006-05-18
EP2308471A1 (en) 2011-04-13
PL213192B1 (pl) 2013-01-31
ATE546132T1 (de) 2012-03-15
AU2004206731B2 (en) 2008-03-20
EP1592401B1 (en) 2012-02-22
PE20040826A1 (es) 2004-12-23
US20060122265A1 (en) 2006-06-08
KR20050096940A (ko) 2005-10-06
RU2005126328A (ru) 2006-07-27
KR20070087181A (ko) 2007-08-27
IL169484A (en) 2016-03-31
CA2509796A1 (en) 2004-08-05
WO2004064806A2 (en) 2004-08-05
TW200505505A (en) 2005-02-16
US20090209639A1 (en) 2009-08-20
KR20100120321A (ko) 2010-11-15
US8008511B2 (en) 2011-08-30
ECSP055918A (es) 2005-11-22
KR20090115898A (ko) 2009-11-09
PL393385A1 (pl) 2011-03-14
CA2706900A1 (en) 2004-08-05
AU2004206731A1 (en) 2004-08-05
KR20090115821A (ko) 2009-11-06
DK1592401T3 (da) 2012-05-21
CA2509796C (en) 2010-09-14
SG155046A1 (en) 2009-09-30
IL169484A0 (en) 2007-07-04
AR043343A1 (es) 2005-07-27
NZ541073A (en) 2008-12-24
KR101129105B1 (ko) 2012-04-12

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