PL377236A1 - Indazoloamidy wykazujące działanie przeciwbólowe - Google Patents
Indazoloamidy wykazujące działanie przeciwbóloweInfo
- Publication number
- PL377236A1 PL377236A1 PL377236A PL37723604A PL377236A1 PL 377236 A1 PL377236 A1 PL 377236A1 PL 377236 A PL377236 A PL 377236A PL 37723604 A PL37723604 A PL 37723604A PL 377236 A1 PL377236 A1 PL 377236A1
- Authority
- PL
- Poland
- Prior art keywords
- indazolamides
- analgesic activity
- analgesic
- activity
- Prior art date
Links
- DITBWPUMEUDVLU-UHFFFAOYSA-N 1h-indazole-3-carboxamide Chemical class C1=CC=C2C(C(=O)N)=NNC2=C1 DITBWPUMEUDVLU-UHFFFAOYSA-N 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000287A ITMI20030287A1 (it) | 2003-02-18 | 2003-02-18 | Indazolammidi dotate di attivita' analgesica metodo, per |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL377236A1 true PL377236A1 (pl) | 2006-01-23 |
| PL215870B1 PL215870B1 (pl) | 2014-02-28 |
Family
ID=32894157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL377236A PL215870B1 (pl) | 2003-02-18 | 2004-01-26 | Indazoloamidy, sposoby ich otrzymywania, kompozycje farmaceutyczne zawierajace te indazoloamidy oraz produkty posrednie powstajace przy wytwarzaniu tych indazoloamidów |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US7632849B2 (pl) |
| EP (1) | EP1594859B1 (pl) |
| JP (1) | JP4724651B2 (pl) |
| KR (1) | KR101108222B1 (pl) |
| CN (2) | CN101139341B (pl) |
| AR (1) | AR043186A1 (pl) |
| AT (1) | ATE471934T1 (pl) |
| AU (1) | AU2004213104B2 (pl) |
| CA (1) | CA2511984C (pl) |
| DE (1) | DE602004027792D1 (pl) |
| DK (1) | DK1594859T3 (pl) |
| EA (1) | EA009077B1 (pl) |
| ES (1) | ES2345983T3 (pl) |
| GE (1) | GEP20074075B (pl) |
| IL (1) | IL169285A (pl) |
| IT (1) | ITMI20030287A1 (pl) |
| MX (1) | MXPA05008730A (pl) |
| PL (1) | PL215870B1 (pl) |
| PT (1) | PT1594859E (pl) |
| SI (1) | SI1594859T1 (pl) |
| UA (1) | UA79537C2 (pl) |
| WO (1) | WO2004074275A1 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20031468A1 (it) * | 2003-07-18 | 2005-01-19 | Acraf | Farmaco ativo nel dolore neuropatico |
| BRPI0512046A (pt) * | 2004-06-15 | 2008-02-06 | Pfizer | derivados de ácido benzimidazolona carboxìlico |
| US8232290B2 (en) * | 2008-03-25 | 2012-07-31 | Affectis Pharmaceuticals Ag | P2X7R antagonists and their use |
| US8815892B2 (en) | 2008-03-25 | 2014-08-26 | Affectis Pharmaceuticals Ag | P2X7R antagonists and their use |
| EP2243772B1 (en) * | 2009-04-14 | 2012-01-18 | Affectis Pharmaceuticals AG | Novel P2X7R antagonists and their use |
| WO2013124158A1 (en) * | 2012-02-21 | 2013-08-29 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | 1h-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors |
| PT2817301E (pt) | 2012-02-21 | 2016-03-14 | Aziende Chimiche Riunite Angelini Francesco - A C R A F - S P A | Utlização de compostos de 1h-indazolo-3-carboxamida como inibidores da cinase 3 beta da sintase do glicogénio |
| US8889730B2 (en) | 2012-04-10 | 2014-11-18 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
| CA2905242C (en) | 2013-03-15 | 2016-11-29 | Pfizer Inc. | Indole compounds that activate ampk |
| MA52557A (fr) | 2018-05-07 | 2021-03-17 | Acraf | Composés de 1h-indazole-3-carboxamide utilisés en tant qu'inhibiteurs de la glycogène synthase kinase 3 bêta |
| CN109336890B (zh) * | 2018-11-17 | 2020-03-20 | 重庆文理学院 | 一种吲唑类衍生物的合成方法及抗肿瘤应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3705175A (en) * | 1969-04-01 | 1972-12-05 | Egyt Gyogyszervegyeszeti Gyar | Indazole-3-carboxylic amides |
| US5654320A (en) * | 1995-03-16 | 1997-08-05 | Eli Lilly And Company | Indazolecarboxamides |
| IL117438A (en) | 1995-03-16 | 2001-12-23 | Lilly Co Eli | Indazolecarboxamides, their preparation and pharmaceutical compositions containing them |
| EP0829474B1 (en) | 1995-05-31 | 2003-04-09 | Nisshin Seifun Group Inc. | Indazole derivatives having monocyclic amino group |
| WO1997017208A1 (fr) * | 1995-11-08 | 1997-05-15 | Toray Industries, Inc. | Plaque planographique originale, sans eau, pour dessin direct |
| KR100494278B1 (ko) | 1996-08-16 | 2005-06-13 | 스미스클라인비이참피이엘시이 | N-[(1-n-부틸-4-피페리딜)메틸]-3,4-디히드로-2H-[1,3]옥사지노[3,2-a] 인돌-10-카르복사미드 및 그의 염의 제조방법 및 그의 제조 중간체 |
| IT1291569B1 (it) | 1997-04-15 | 1999-01-11 | Angelini Ricerche Spa | Indazolammidi come agenti serotoninergici |
| US6339087B1 (en) * | 1997-08-18 | 2002-01-15 | Syntex (U.S.A.) Llc | Cyclic amine derivatives-CCR-3 receptor antagonists |
| US6069152A (en) * | 1997-10-07 | 2000-05-30 | Eli Lilly And Company | 5-HT4 agonists and antagonists |
| NZ507567A (en) * | 1998-04-21 | 2003-08-29 | Du Pont Pharm Co | 5-aminoindeno(1,2-c)pyrazol-4-ones as anti-cancer and anti-proliferative agents |
| US6407103B2 (en) * | 1998-04-21 | 2002-06-18 | Bristol-Myers Squibb Pharma Company | Indeno [1,2-c] pyrazol-4-ones and their uses |
-
2003
- 2003-02-18 IT IT000287A patent/ITMI20030287A1/it unknown
-
2004
- 2004-01-26 EA EA200501164A patent/EA009077B1/ru not_active IP Right Cessation
- 2004-01-26 JP JP2006501608A patent/JP4724651B2/ja not_active Expired - Fee Related
- 2004-01-26 DE DE602004027792T patent/DE602004027792D1/de not_active Expired - Lifetime
- 2004-01-26 GE GEAP20048983A patent/GEP20074075B/en unknown
- 2004-01-26 PT PT04705070T patent/PT1594859E/pt unknown
- 2004-01-26 CN CN2007101801011A patent/CN101139341B/zh not_active Expired - Fee Related
- 2004-01-26 UA UAA200508163A patent/UA79537C2/uk unknown
- 2004-01-26 DK DK04705070.3T patent/DK1594859T3/da active
- 2004-01-26 EP EP04705070A patent/EP1594859B1/en not_active Expired - Lifetime
- 2004-01-26 CN CNB2004800025681A patent/CN100347168C/zh not_active Expired - Fee Related
- 2004-01-26 ES ES04705070T patent/ES2345983T3/es not_active Expired - Lifetime
- 2004-01-26 AU AU2004213104A patent/AU2004213104B2/en not_active Ceased
- 2004-01-26 AT AT04705070T patent/ATE471934T1/de active
- 2004-01-26 PL PL377236A patent/PL215870B1/pl unknown
- 2004-01-26 SI SI200431488T patent/SI1594859T1/sl unknown
- 2004-01-26 MX MXPA05008730A patent/MXPA05008730A/es active IP Right Grant
- 2004-01-26 KR KR1020057014055A patent/KR101108222B1/ko not_active Expired - Fee Related
- 2004-01-26 WO PCT/EP2004/000647 patent/WO2004074275A1/en not_active Ceased
- 2004-01-26 US US10/541,209 patent/US7632849B2/en not_active Expired - Fee Related
- 2004-01-26 CA CA2511984A patent/CA2511984C/en not_active Expired - Fee Related
- 2004-02-16 AR ARP040100467A patent/AR043186A1/es not_active Application Discontinuation
-
2005
- 2005-06-20 IL IL169285A patent/IL169285A/en not_active IP Right Cessation
-
2009
- 2009-10-28 US US12/607,463 patent/US8519139B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HU0302451D0 (en) | New compounds with therapeutic effect | |
| ZA200508388B (en) | Macrolide-Conjugates with anti-inflammatory activity | |
| GB0704141D0 (en) | Topical medicament | |
| PL377236A1 (pl) | Indazoloamidy wykazujące działanie przeciwbólowe | |
| GB0418540D0 (en) | Use | |
| EP1820505A4 (en) | ANALGESIC | |
| SI1622892T1 (sl) | Indazoli, ki imajo analgetsko aktivnost | |
| GB0407301D0 (en) | Use | |
| GB2401043B (en) | Drug | |
| IL180487A0 (en) | Medicament | |
| GB0410015D0 (en) | Use | |
| GB0424565D0 (en) | Activity aid | |
| HRP20040318A2 (en) | Furochromen derivative with anti-inflammaroty activity | |
| GB0412878D0 (en) | Use | |
| GB0409098D0 (en) | Medicament | |
| GB0426942D0 (en) | Medicament | |
| EP1624073A4 (en) | DRUG | |
| GB0424494D0 (en) | Use | |
| GB0328797D0 (en) | Easy klik | |
| GB0313558D0 (en) | Easy strimmer | |
| GB0403149D0 (en) | Medicament | |
| GB0327912D0 (en) | Medicament | |
| GB0301842D0 (en) | Medicament | |
| GB0327913D0 (en) | Medicament | |
| GB0414361D0 (en) | Privatise easy |