PL377517A1 - Modyfikowane na atomie C-9 indazolilopirolotriazyny - Google Patents

Modyfikowane na atomie C-9 indazolilopirolotriazyny

Info

Publication number: PL377517A1
Authority: PL; Poland
Prior art keywords: indazolylpyrrolotriazines; modified; modified indazolylpyrrolotriazines
Prior art date: 2002-12-13

Application number

PL377517A

Other languages

English (en)

Inventor

Gregory D. Vite

Ashvinikumar V. Gavai

Brian E. Fink

Harold Mastalerz

John F. Kadow

Original Assignee

Bristol-Myers Squibb Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-13

Filing date

2003-12-12

Publication date

2006-02-06

2003-12-12 Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company

2006-02-06 Publication of PL377517A1 publication Critical patent/PL377517A1/pl

Links

-1 C-6 modified indazolylpyrrolotriazines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Immunology (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Inks, Pencil-Leads, Or Crayons (AREA)

PL377517A 2002-12-13 2003-12-12 Modyfikowane na atomie C-9 indazolilopirolotriazyny PL377517A1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US43319002P	2002-12-13	2002-12-13

Publications (1)

Publication Number	Publication Date
PL377517A1 true PL377517A1 (pl)	2006-02-06

Family

ID=32595133

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL377517A PL377517A1 (pl)	2002-12-13	2003-12-12	Modyfikowane na atomie C-9 indazolilopirolotriazyny

Country Status (27)

Country	Link
US (2)	US6916815B2 (pl)
EP (1)	EP1569937B1 (pl)
JP (1)	JP4511367B2 (pl)
KR (1)	KR101073801B1 (pl)
CN (2)	CN101723948A (pl)
AR (1)	AR042450A1 (pl)
AT (1)	ATE534648T1 (pl)
AU (1)	AU2003300877B2 (pl)
BR (1)	BR0316755A (pl)
CA (1)	CA2509650C (pl)
CO (1)	CO5570660A2 (pl)
DK (1)	DK1569937T3 (pl)
ES (1)	ES2374393T3 (pl)
HR (1)	HRP20050535A2 (pl)
IS (1)	IS7890A (pl)
MX (1)	MXPA05006164A (pl)
NO (1)	NO20052733L (pl)
NZ (1)	NZ540338A (pl)
PE (1)	PE20040805A1 (pl)
PL (1)	PL377517A1 (pl)
PT (1)	PT1569937E (pl)
RS (1)	RS20050441A (pl)
RU (1)	RU2356903C2 (pl)
TW (1)	TW200420565A (pl)
UA (1)	UA80591C2 (pl)
WO (1)	WO2004054514A2 (pl)
ZA (1)	ZA200504507B (pl)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6242469B1 (en) *	1996-12-03	2001-06-05	Sloan-Kettering Institute For Cancer Research	Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US7625859B1 (en) *	2000-02-16	2009-12-01	Oregon Health & Science University	HER-2 binding antagonists
US7393823B1 (en)	1999-01-20	2008-07-01	Oregon Health And Science University	HER-2 binding antagonists
US6867300B2 (en)	2000-11-17	2005-03-15	Bristol-Myers Squibb Company	Methods for the preparation of pyrrolotriazine compounds useful as kinase inhibitors
US20090197852A9 (en) *	2001-08-06	2009-08-06	Johnson Robert G Jr	Method of treating breast cancer using 17-AAG or 17-AG or a prodrug of either in combination with a HER2 inhibitor
EP1497019B1 (en) *	2002-04-23	2015-05-20	Bristol-Myers Squibb Company	Pyrrolo-triazine aniline compounds useful as kinase inhibitors
JP2005529890A (ja)	2002-04-23	2005-10-06	ブリストル−マイヤーズ　スクイブ　カンパニー	キナーゼ阻害剤として有用なアリールケトンピロロトリアジン化合物
TWI329112B (en) *	2002-07-19	2010-08-21	Bristol Myers Squibb Co	Novel inhibitors of kinases
US6921769B2 (en)	2002-08-23	2005-07-26	Sloan-Kettering Institute For Cancer Research	Synthesis of epothilones, intermediates thereto and analogues thereof
US7649006B2 (en)	2002-08-23	2010-01-19	Sloan-Kettering Institute For Cancer Research	Synthesis of epothilones, intermediates thereto and analogues thereof
WO2004018478A2 (en)	2002-08-23	2004-03-04	Sloan-Kettering Institute For Cancer Research	Synthesis of epothilones, intermediates thereto, analogues and uses thereof
TW200420565A (en) *	2002-12-13	2004-10-16	Bristol Myers Squibb Co	C-6 modified indazolylpyrrolotriazines
MXPA05008183A (es)	2003-02-05	2005-10-05	Bristol Myers Squibb Co	Proceso para preparar pirrolotriazina como inhibidores de cinasa.
ES2428358T3 (es) *	2003-10-17	2013-11-07	Novo Nordisk A/S	Terapia de combinación
US7102001B2 (en)	2003-12-12	2006-09-05	Bristol-Myers Squibb Company	Process for preparing pyrrolotriazine
US20060014741A1 (en) *	2003-12-12	2006-01-19	Dimarco John D	Synthetic process, and crystalline forms of a pyrrolotriazine compound
MY145634A (en) *	2003-12-29	2012-03-15	Bristol Myers Squibb Co	Pyrrolotriazine compounds as kinase inhibitors
US7064203B2 (en) *	2003-12-29	2006-06-20	Bristol Myers Squibb Company	Di-substituted pyrrolotriazine compounds
US7459562B2 (en)	2004-04-23	2008-12-02	Bristol-Myers Squibb Company	Monocyclic heterocycles as kinase inhibitors
TW200538453A (en)	2004-04-26	2005-12-01	Bristol Myers Squibb Co	Bicyclic heterocycles as kinase inhibitors
US7102002B2 (en) *	2004-06-16	2006-09-05	Bristol-Myers Squibb Company	Pyrrolotriazine kinase inhibitors
US7439246B2 (en)	2004-06-28	2008-10-21	Bristol-Myers Squibb Company	Fused heterocyclic kinase inhibitors
US20050288290A1 (en)	2004-06-28	2005-12-29	Borzilleri Robert M	Fused heterocyclic kinase inhibitors
US7432373B2 (en)	2004-06-28	2008-10-07	Bristol-Meyers Squibb Company	Processes and intermediates useful for preparing fused heterocyclic kinase inhibitors
TW200600513A (en) *	2004-06-30	2006-01-01	Bristol Myers Squibb Co	A method for preparing pyrrolotriazine compounds
US7253167B2 (en) *	2004-06-30	2007-08-07	Bristol-Myers Squibb Company	Tricyclic-heteroaryl compounds useful as kinase inhibitors
US7102003B2 (en) *	2004-07-01	2006-09-05	Bristol-Myers Squibb Company	Pyrrolotriazine compounds
US7504521B2 (en)	2004-08-05	2009-03-17	Bristol-Myers Squibb Co.	Methods for the preparation of pyrrolotriazine compounds
TW200618803A (en)	2004-08-12	2006-06-16	Bristol Myers Squibb Co	Process for preparing pyrrolotriazine aniline compounds useful as kinase inhibitors
WO2006042002A2 (en) *	2004-10-05	2006-04-20	Oregon Health And Science University	Compositions and methods for treating disease
US7151176B2 (en) *	2004-10-21	2006-12-19	Bristol-Myers Squibb Company	Pyrrolotriazine compounds
MX2007012887A (es)	2005-04-18	2007-12-10	Novo Nordisk As	Variantes il-21.
US7402582B2 (en) *	2005-07-01	2008-07-22	Bristol-Myers Squibb Company	Pyrrolotriazine compounds useful as kinase inhibitors and methods of treating kinase-associated conditions therewith
US7405213B2 (en) *	2005-07-01	2008-07-29	Bristol-Myers Squibb Company	Pyrrolotriazine compounds useful as kinase inhibitors and methods of treating kinase-associated conditions therewith
WO2007035428A1 (en)	2005-09-15	2007-03-29	Bristol-Myers Squibb Company	Met kinase inhibitors
US7547782B2 (en)	2005-09-30	2009-06-16	Bristol-Myers Squibb Company	Met kinase inhibitors
US7514435B2 (en) *	2005-11-18	2009-04-07	Bristol-Myers Squibb Company	Pyrrolotriazine kinase inhibitors
US7348325B2 (en)	2005-11-30	2008-03-25	Bristol-Myers Squibb Company	Pyrrolotriazine kinase inhibitors
US8063208B2 (en)	2006-02-16	2011-11-22	Bristol-Myers Squibb Company	Crystalline forms of (3R,4R)-4-amino-1-[[4-[(3-methoxyphenyl)amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-3-ol
CA2645031A1 (en)	2006-03-07	2007-09-13	Bristol-Myers Squibb Company	Pyrrolotriazine aniline prodrug compounds useful as kinase inhibitors
WO2008049920A2 (en)	2006-10-26	2008-05-02	Novo Nordisk A/S	Il-21 variants
WO2008074863A1 (en) *	2006-12-21	2008-06-26	Novo Nordisk A/S	Interleukin-21 variants with altered binding to the il-21 receptor
US20090083483A1 (en) *	2007-09-24	2009-03-26	International Business Machines Corporation	Power Conservation In A RAID Array
US8166326B2 (en) *	2007-11-08	2012-04-24	International Business Machines Corporation	Managing power consumption in a computer
US20090132842A1 (en) *	2007-11-15	2009-05-21	International Business Machines Corporation	Managing Computer Power Consumption In A Computer Equipment Rack
US8041521B2 (en) *	2007-11-28	2011-10-18	International Business Machines Corporation	Estimating power consumption of computing components configured in a computing system
JP2011516498A (ja)	2008-04-04	2011-05-26	ギリアードサイエンシーズ，インコーポレイテッド	ステアロイル−ＣｏＡデサチュラーゼの阻害剤として使用するためのトリアゾロピリジノン誘導体
CA2719362A1 (en) *	2008-04-04	2009-10-08	Gilead Sciences, Inc.	Pyrrolotriazinone derivatives for use as stearoyl coa desaturase inhibitors
WO2009126311A1 (en) *	2008-04-11	2009-10-15	The University Of Texas, M.D. Anderson Cancer Center	Radiosensitization of tumors with indazolpyrrolotriazines for radiotherapy
US8103884B2 (en)	2008-06-25	2012-01-24	International Business Machines Corporation	Managing power consumption of a computer
US8041976B2 (en) *	2008-10-01	2011-10-18	International Business Machines Corporation	Power management for clusters of computers
US8514215B2 (en) *	2008-11-12	2013-08-20	International Business Machines Corporation	Dynamically managing power consumption of a computer with graphics adapter configurations
EP2376491B1 (en)	2008-12-19	2015-03-04	Cephalon, Inc.	Pyrrolotriazines as alk and jak2 inhibitors
JP2012520314A (ja) *	2009-03-11	2012-09-06	アムビトビオスシエンセスコルポラチオン	癌治療のためのインダゾリルアミノピロロトリアジンとタキサンの併用
WO2011112689A2 (en)	2010-03-11	2011-09-15	Ambit Biosciences Corp.	Saltz of an indazolylpyrrolotriazine
US9724352B2 (en)	2012-05-31	2017-08-08	Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences	Pyrrolo[2,1-F[1,2,4]triazine compounds, preparation methods and applications thereof
CN103450204B (zh)	2012-05-31	2016-08-17	中国科学院上海药物研究所	吡咯[2，1-f][1，2，4]并三嗪类化合物，其制备方法及用途
US9050345B2 (en) *	2013-03-11	2015-06-09	Bristol-Myers Squibb Company	Pyrrolotriazines as potassium ion channel inhibitors
WO2014143607A1 (en) *	2013-03-11	2014-09-18	Bristol-Myers Squibb Company	Pyrrolopyridazines as potassium ion channel inhibitors
EP2970294B1 (en) *	2013-03-11	2016-12-28	Bristol-Myers Squibb Company	Pyrrolotriazines as potassium ion channel inhibitors
WO2015081783A1 (zh) *	2013-12-06	2015-06-11	江苏奥赛康药业股份有限公司	吡咯并[2,1-f][1,2,4]三嗪类衍生物及其制备方法和用途
CN111533708B (zh) *	2020-06-12	2021-03-16	上海馨远医药科技有限公司	一种手性n-叔丁氧羰基吗啉-3-羧酸的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4908056A (en) *	1986-04-25	1990-03-13	E. I. Du Pont De Nemours And Company	Heterocyclic acyl sulfonamides
EP0778277B1 (en)	1995-12-08	2003-06-25	Pfizer Inc.	Substituted heterocyclic derivatives as CRF antagonists
TR199900389T2 (xx)	1996-08-28	2000-06-21	Pfizer Inc.	�kame edilmi� 6,5-hetero-bisiklik t�revleri.
CZ303660B6 (cs) *	1999-05-21	2013-02-13	Bristol-Myers Squibb Company	Pyrrolotriazin a farmaceutický prostredek s jeho obsahem
US6787545B1 (en)	1999-08-23	2004-09-07	Shiongi & Co., Ltd.	Pyrrolotriazine derivatives having spla2-inhibitory activities
US6867300B2 (en)	2000-11-17	2005-03-15	Bristol-Myers Squibb Company	Methods for the preparation of pyrrolotriazine compounds useful as kinase inhibitors
KR100847605B1 (ko) *	2000-11-17	2008-07-21	브리스톨-마이어스스퀴브컴파니	ｐ38 키나제 관련 질병의 치료 방법 및 키나제 억제제로서유용한 피롤로트리아진 화합물
TW200300350A (en)	2001-11-14	2003-06-01	Bristol Myers Squibb Co	C-5 modified indazolylpyrrolotriazines
JP2005529890A (ja) *	2002-04-23	2005-10-06	ブリストル−マイヤーズ　スクイブ　カンパニー	キナーゼ阻害剤として有用なアリールケトンピロロトリアジン化合物
EP1497019B1 (en) *	2002-04-23	2015-05-20	Bristol-Myers Squibb Company	Pyrrolo-triazine aniline compounds useful as kinase inhibitors
TW200400034A (en) *	2002-05-20	2004-01-01	Bristol Myers Squibb Co	Pyrazolo-pyrimidine aniline compounds useful as kinase inhibitors
TWI329112B (en)	2002-07-19	2010-08-21	Bristol Myers Squibb Co	Novel inhibitors of kinases
TW200420565A (en) *	2002-12-13	2004-10-16	Bristol Myers Squibb Co	C-6 modified indazolylpyrrolotriazines
US7102001B2 (en) *	2003-12-12	2006-09-05	Bristol-Myers Squibb Company	Process for preparing pyrrolotriazine

2003
- 2003-12-08 TW TW092134601A patent/TW200420565A/zh unknown
- 2003-12-12 CA CA002509650A patent/CA2509650C/en not_active Expired - Fee Related
- 2003-12-12 EP EP03813396A patent/EP1569937B1/en not_active Expired - Lifetime
- 2003-12-12 JP JP2004560804A patent/JP4511367B2/ja not_active Expired - Fee Related
- 2003-12-12 AT AT03813396T patent/ATE534648T1/de active
- 2003-12-12 KR KR1020057010549A patent/KR101073801B1/ko not_active Expired - Fee Related
- 2003-12-12 RS YUP-2005/0441A patent/RS20050441A/sr unknown
- 2003-12-12 CN CN200910246410A patent/CN101723948A/zh active Pending
- 2003-12-12 PE PE2003001275A patent/PE20040805A1/es not_active Application Discontinuation
- 2003-12-12 PL PL377517A patent/PL377517A1/pl not_active Application Discontinuation
- 2003-12-12 PT PT03813396T patent/PT1569937E/pt unknown
- 2003-12-12 UA UAA200506891A patent/UA80591C2/uk unknown
- 2003-12-12 WO PCT/US2003/039542 patent/WO2004054514A2/en not_active Ceased
- 2003-12-12 AR ARP030104592A patent/AR042450A1/es unknown
- 2003-12-12 NZ NZ540338A patent/NZ540338A/en not_active IP Right Cessation
- 2003-12-12 RU RU2005120650/04A patent/RU2356903C2/ru not_active IP Right Cessation
- 2003-12-12 MX MXPA05006164A patent/MXPA05006164A/es active IP Right Grant
- 2003-12-12 ES ES03813396T patent/ES2374393T3/es not_active Expired - Lifetime
- 2003-12-12 BR BR0316755-0A patent/BR0316755A/pt not_active IP Right Cessation
- 2003-12-12 HR HR20050535A patent/HRP20050535A2/hr not_active Application Discontinuation
- 2003-12-12 DK DK03813396.3T patent/DK1569937T3/da active
- 2003-12-12 AU AU2003300877A patent/AU2003300877B2/en not_active Ceased
- 2003-12-12 CN CNA200380105906XA patent/CN1726216A/zh active Pending
- 2003-12-15 US US10/736,476 patent/US6916815B2/en not_active Expired - Fee Related
2005
- 2005-06-01 ZA ZA200504507A patent/ZA200504507B/en unknown
- 2005-06-02 US US11/143,279 patent/US7148220B2/en not_active Expired - Fee Related
- 2005-06-07 NO NO20052733A patent/NO20052733L/no not_active Application Discontinuation
- 2005-06-10 IS IS7890A patent/IS7890A/is unknown
- 2005-06-13 CO CO05057043A patent/CO5570660A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO20052733L (no)	2005-07-07
IS7890A (is)	2005-06-10
CA2509650A1 (en)	2004-07-01
ATE534648T1 (de)	2011-12-15
WO2004054514A2 (en)	2004-07-01
US20040142931A1 (en)	2004-07-22
US20050222153A1 (en)	2005-10-06
PE20040805A1 (es)	2004-11-20
ES2374393T3 (es)	2012-02-16
EP1569937B1 (en)	2011-11-23
US7148220B2 (en)	2006-12-12
US6916815B2 (en)	2005-07-12
DK1569937T3 (da)	2012-01-02
AR042450A1 (es)	2005-06-22
CN101723948A (zh)	2010-06-09
TW200420565A (en)	2004-10-16
PT1569937E (pt)	2012-01-04
BR0316755A (pt)	2005-10-25
EP1569937A4 (en)	2007-08-08
MXPA05006164A (es)	2005-08-26
CA2509650C (en)	2007-10-30
WO2004054514A3 (en)	2004-10-07
CO5570660A2 (es)	2005-10-31
RU2356903C2 (ru)	2009-05-27
KR20050084242A (ko)	2005-08-26
RU2005120650A (ru)	2006-01-20
ZA200504507B (en)	2006-08-30
AU2003300877B2 (en)	2010-02-18
UA80591C2 (en)	2007-10-10
KR101073801B1 (ko)	2011-10-13
NO20052733D0 (no)	2005-06-07
JP2006509826A (ja)	2006-03-23
JP4511367B2 (ja)	2010-07-28
NZ540338A (en)	2008-05-30
RS20050441A (sr)	2007-04-10
HRP20050535A2 (en)	2005-12-31
EP1569937A2 (en)	2005-09-07
AU2003300877A1 (en)	2004-07-09
CN1726216A (zh)	2006-01-25

Legal Events

Date	Code	Title	Description
2013-02-28	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
EP1569937A4 (en)	2007-08-08	INDIZOLYLPYRROLOTRIAZINES C-6 MODIFIED
DE50311874D1 (en)	2009-10-15	Spirocyclische cyclohexan-derivate
DE50312422D1 (en)	2010-04-01	Aryloxime
AU2003249738A8 (en)	2004-01-23	Ostoscope
AU2003297193A8 (en)	2004-07-09	Meta-web
IL163652A0 (en)	2005-12-18	Substituted hydroxyethylamines
DE50309217D1 (en)	2008-04-03	Benzimidazolderivate
AU2003252028A8 (en)	2004-02-09	Heterodiamondoids
AU2003279495A8 (en)	2004-05-13	Alert-modeling
DE50303619D1 (en)	2006-07-06	Reibschweissvorrichtung
DE50308027D1 (en)	2007-10-04	Cyclohexyl-harnstoff-derivate
DE50311133D1 (en)	2009-03-12	Carbonsäureamide
DE50307787D1 (en)	2007-09-06	Isophthalsäurederivate
DE50312412D1 (en)	2010-03-25	4-hydroxymethyl-1-aryl-cyclohexylamin-derivative
PT1487778E (pt)	2012-07-26	Formulação farmacêutica oral na forma de suspensão aquosa de microcápsulas para libertação modificada de princípio(s) activo(s)
AU2003264900A8 (en)	2004-04-08	Cast-cutter
DE50310169D1 (en)	2008-08-28	Lingual-retainer
DE50304964D1 (en)	2006-10-19	Handhobelmaschine
IL166740A0 (en)	2006-01-15	Substituted heterocyclylpyrimidines
AU2002367810A8 (en)	2003-11-10	Bis-transition-metal-chelate-probes
AU2003262681A8 (en)	2004-03-03	Hemo-aide
DE10392833D2 (en)	2005-06-09	Geotextilie
PL377325A1 (pl)	2006-01-23	Podstawione benzodioksepiny
AU2003253735A8 (en)	2004-01-06	Vacuolins
AU2002341221A8 (en)	2004-04-19	Honey-brandy