PL377732A1 - Nowa synergistyczna kombinacja zawierająca roflumilast i formoterol - Google Patents

Nowa synergistyczna kombinacja zawierająca roflumilast i formoterol

Info

Publication number: PL377732A1
Authority: PL; Poland
Prior art keywords: roflumilast; formoterol; synergistic combination; new synergistic; new
Prior art date: 2002-11-27

Application number

PL377732A

Other languages

English (en)

Other versions

PL216752B1 (pl

Inventor

Rolf Beume

Daniela Bundschuh

Norbert Kolassa

Degenhard Marx

Christian Weimar

Original Assignee

Altana Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-27

Filing date

2003-11-26

Publication date

2006-02-06

2003-11-26 Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag

2006-02-06 Publication of PL377732A1 publication Critical patent/PL377732A1/pl

2014-05-30 Publication of PL216752B1 publication Critical patent/PL216752B1/pl

Links

BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 title abstract 2
229960002848 formoterol Drugs 0.000 title abstract 2
MNDBXUUTURYVHR-UHFFFAOYSA-N roflumilast Chemical compound FC(F)OC1=CC=C(C(=O)NC=2C(=CN=CC=2Cl)Cl)C=C1OCC1CC1 MNDBXUUTURYVHR-UHFFFAOYSA-N 0.000 title abstract 2
229960002586 roflumilast Drugs 0.000 title abstract 2
239000011885 synergistic combination Substances 0.000 title 1
208000018569 Respiratory Tract disease Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicinal Preparation (AREA)

PL377732A 2002-11-27 2003-11-26 Środek leczniczy do zapobiegania objawom lub do leczenia chorób dróg oddechowych u ludzi i zastosowanie PL216752B1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02026505		2002-11-27

Publications (2)

Publication Number	Publication Date
PL377732A1 true PL377732A1 (pl)	2006-02-06
PL216752B1 PL216752B1 (pl)	2014-05-30

Family

ID=32338002

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL377732A PL216752B1 (pl)	2002-11-27	2003-11-26	Środek leczniczy do zapobiegania objawom lub do leczenia chorób dróg oddechowych u ludzi i zastosowanie

Country Status (31)

Country	Link
US (1)	US20060142308A1 (pl)
EP (1)	EP1567139B1 (pl)
JP (1)	JP2006508994A (pl)
KR (1)	KR101071798B1 (pl)
CN (1)	CN100346777C (pl)
AT (1)	ATE399543T1 (pl)
AU (1)	AU2003292120B2 (pl)
BR (1)	BR0316451A (pl)
CA (1)	CA2506962C (pl)
CO (1)	CO5690570A2 (pl)
CY (1)	CY1110369T1 (pl)
DE (1)	DE60321953D1 (pl)
DK (1)	DK1567139T3 (pl)
EA (1)	EA009935B1 (pl)
ES (1)	ES2309357T3 (pl)
HR (1)	HRP20050579B1 (pl)
IL (1)	IL168308A (pl)
IS (1)	IS2575B (pl)
MA (1)	MA27539A1 (pl)
ME (1)	ME00489B (pl)
MX (1)	MXPA05005437A (pl)
NO (1)	NO334247B1 (pl)
NZ (1)	NZ540659A (pl)
PL (1)	PL216752B1 (pl)
PT (1)	PT1567139E (pl)
RS (1)	RS51081B (pl)
SI (1)	SI1567139T1 (pl)
TN (1)	TNSN05131A1 (pl)
UA (1)	UA83018C2 (pl)
WO (1)	WO2004047829A1 (pl)
ZA (1)	ZA200503308B (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY140561A (en) *	2002-02-20	2009-12-31	Nycomed Gmbh	Dosage form containing pde 4 inhibitor as active ingredient
SI1606261T1 (sl)	2003-03-10	2010-03-31	Nycomed Gmbh	Novi postopek za pripravo roflumilasta
US8663694B2 (en) *	2005-03-16	2014-03-04	Takeda Gmbh	Taste masked dosage form containing roflumilast
DE102005030733A1 (de) *	2005-07-01	2007-01-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
RS53084B (sr) *	2006-07-05	2014-06-30	Takeda Gmbh	Kombinacija inhibitora hmg-coa reduktaze rosuvastatina sa inhibitorom fosfodiesteraze 4, kao što je roflumilast, roflumilast-n-oksid za lečenje inflamatornih plućnih obolenja
WO2013077830A1 (en) *	2011-11-25	2013-05-30	Mahmut Bilgic	Synergistilly active combinations of roflumilast and carmoterol
US20130172303A1 (en) *	2012-01-03	2013-07-04	Forest Laboratories Holdings Ltd.	Roflumilast compositions for the treatment of copd
DK2948148T3 (da) *	2013-01-28	2020-10-26	Incozen Therapeutics Pvt Ltd	Metoder til behandling af autoimmune, åndedræts- og betændelsesforstyrrelser ved inhalation af roflumilast n-oxid
CN104800214A (zh) *	2014-01-27	2015-07-29	成都英诺新科技有限公司	一种罗氟司特吸入气雾剂复方及制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5795564A (en) *	1991-04-05	1998-08-18	Sepracor, Inc.	Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
CN1046939C (zh) *	1993-07-02	1999-12-01	比克·古尔顿·劳姆贝尔格化学公司	氟烷氧基取代的苯甲酰胺类及其制备方法和应用
DE69835594T2 (de) *	1997-02-17	2007-08-16	Altana Pharma Ag	Zusammensetzungen zur behandlung von irds oder ards die 3-(cyclopropylmethoxy)-n-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy) benzamid und lungensurfactant enthalten
DK0975347T3 (da) *	1997-02-28	2008-06-16	Nycomed Gmbh	Synergistisk kombination af PDE-inhibitorer og adenylatcyclase-agonister eller guanylcyclyseagonister
US6624181B1 (en) *	1997-02-28	2003-09-23	Altana Pharma Ag	Synergistic combination
TR200100500T2 (tr) *	1998-08-26	2001-06-21	Smithkline Beecham Corporation	Pulmoner hastalıkların tedavisi için terapiler
US6303145B2 (en) *	1999-05-10	2001-10-16	Sepracor Inc.	(S,R) formoterol methods and compositions
CZ302882B6 (cs) *	1999-08-21	2012-01-04	Nycomed Gmbh	Farmaceutický prostredek
GB0103630D0 (en) *	2001-02-14	2001-03-28	Glaxo Group Ltd	Chemical compounds
ATE381537T1 (de) *	2001-03-22	2008-01-15	Glaxo Group Ltd	Formanilid-derivative als beta2-adrenorezeptor- agonisten
MY137522A (en) *	2001-04-30	2009-02-27	Glaxo Group Ltd	Novel anti-inflammatory androstane derivatives.

2003
- 2003-11-26 PL PL377732A patent/PL216752B1/pl unknown
- 2003-11-26 CN CNB2003801037450A patent/CN100346777C/zh not_active Expired - Fee Related
- 2003-11-26 RS YUP-2005/0382A patent/RS51081B/sr unknown
- 2003-11-26 JP JP2004554480A patent/JP2006508994A/ja active Pending
- 2003-11-26 PT PT03767663T patent/PT1567139E/pt unknown
- 2003-11-26 AT AT03767663T patent/ATE399543T1/de active
- 2003-11-26 SI SI200331344T patent/SI1567139T1/sl unknown
- 2003-11-26 BR BR0316451-9A patent/BR0316451A/pt not_active IP Right Cessation
- 2003-11-26 AU AU2003292120A patent/AU2003292120B2/en not_active Ceased
- 2003-11-26 EP EP03767663A patent/EP1567139B1/en not_active Expired - Lifetime
- 2003-11-26 EA EA200500774A patent/EA009935B1/ru not_active IP Right Cessation
- 2003-11-26 DE DE60321953T patent/DE60321953D1/de not_active Expired - Lifetime
- 2003-11-26 CA CA2506962A patent/CA2506962C/en not_active Expired - Fee Related
- 2003-11-26 ME MEP-2008-782A patent/ME00489B/me unknown
- 2003-11-26 ES ES03767663T patent/ES2309357T3/es not_active Expired - Lifetime
- 2003-11-26 NZ NZ540659A patent/NZ540659A/en not_active IP Right Cessation
- 2003-11-26 HR HRP20050579AA patent/HRP20050579B1/hr not_active IP Right Cessation
- 2003-11-26 US US10/535,816 patent/US20060142308A1/en not_active Abandoned
- 2003-11-26 KR KR1020057009210A patent/KR101071798B1/ko not_active Expired - Fee Related
- 2003-11-26 WO PCT/EP2003/013275 patent/WO2004047829A1/en not_active Ceased
- 2003-11-26 UA UAA200505966A patent/UA83018C2/uk unknown
- 2003-11-26 MX MXPA05005437A patent/MXPA05005437A/es active IP Right Grant
- 2003-11-26 DK DK03767663T patent/DK1567139T3/da active
2005
- 2005-04-25 ZA ZA200503308A patent/ZA200503308B/en unknown
- 2005-05-01 IL IL168308A patent/IL168308A/en not_active IP Right Cessation
- 2005-05-10 TN TNP2005000131A patent/TNSN05131A1/en unknown
- 2005-06-16 MA MA28343A patent/MA27539A1/fr unknown
- 2005-06-17 NO NO20052999A patent/NO334247B1/no not_active IP Right Cessation
- 2005-06-20 IS IS7898A patent/IS2575B/is unknown
- 2005-06-27 CO CO05062787A patent/CO5690570A2/es not_active Application Discontinuation
2008
- 2008-09-17 CY CY20081101017T patent/CY1110369T1/el unknown

Also Published As

Publication number	Publication date
ME00489B (me)	2011-10-10
CY1110369T1 (el)	2015-04-29
PL216752B1 (pl)	2014-05-30
HRP20050579A2 (hr)	2006-04-30
DE60321953D1 (de)	2008-08-14
RS51081B (sr)	2010-10-31
HRP20050579B1 (hr)	2014-01-31
RS20050382A (sr)	2007-08-03
CA2506962C (en)	2012-01-03
WO2004047829A8 (en)	2005-06-30
TNSN05131A1 (en)	2007-05-14
CN1713903A (zh)	2005-12-28
US20060142308A1 (en)	2006-06-29
MA27539A1 (fr)	2005-09-01
CO5690570A2 (es)	2006-10-31
CA2506962A1 (en)	2004-06-10
KR101071798B1 (ko)	2011-10-11
UA83018C2 (uk)	2008-06-10
ES2309357T3 (es)	2008-12-16
WO2004047829A1 (en)	2004-06-10
SI1567139T1 (sl)	2008-12-31
CN100346777C (zh)	2007-11-07
AU2003292120A1 (en)	2004-06-18
EA009935B1 (ru)	2008-04-28
ZA200503308B (en)	2006-11-29
BR0316451A (pt)	2005-10-11
IS2575B (is)	2010-02-15
NZ540659A (en)	2007-05-31
EP1567139B1 (en)	2008-07-02
KR20050085104A (ko)	2005-08-29
EP1567139A1 (en)	2005-08-31
HK1081861A1 (en)	2006-05-26
EA200500774A1 (ru)	2005-12-29
NO334247B1 (no)	2014-01-20
NO20052999L (no)	2005-06-17
IS7898A (is)	2005-06-20
JP2006508994A (ja)	2006-03-16
DK1567139T3 (da)	2008-11-03
PT1567139E (pt)	2008-10-01
AU2003292120B2 (en)	2010-01-21
ATE399543T1 (de)	2008-07-15
IL168308A (en)	2010-12-30
MXPA05005437A (es)	2005-08-03

Publication	Publication Date	Title
EP1558220A4 (en)	2006-07-12	ORAL COMPOSITIONS FOR THE TREATMENT OF DISEASES
BR0013478A (pt)	2002-04-30	Combinação sinergìstica
WO2004043341A3 (en)	2004-07-15	Treatment for hemorrhagic shock
AU2003301190A1 (en)	2004-07-14	Administration of capsaicinoids
MXPA04003666A (es)	2004-07-22	Uso de flibanserina para tratamiento de trastornos sexuales.
CY1110369T1 (el)	2015-04-29	Νεος συνεργιστικος συνδυασμος ο οποιος περιεχει ροφλουμιλαστη και φορμοτερολη
MXPA05012358A (es)	2006-02-02	Combinacion farmaceutica que comprende modafinilo y otra droga.
PL1656131T3 (pl)	2011-07-29	Zastosowanie betainy w leczeniu chromania przestankowego
CY1110368T1 (el)	2015-04-29	Συνεργιστικος συνδυασμος ο οποιος περιλαμβανει ροφλουμιλαστη και (r,r)-φορμοτερολη
TWI347845B (en)	2011-09-01	Pharmaceutical compositions,combinations,and kits for the treatment of respiratory diseases and use of the same
MX2007007206A (es)	2008-03-26	Uso de un agonista 5-ht6 para el tratamiento y la prevencion de trastornos neurodegenerativos.
YU11904A (sh)	2006-08-17	Upotreba inhibitora il-18 kod poremećaja preosetljivosti
AU2002325687A1 (en)	2003-02-24	Pharmaceutical composition comprising salmeterol and budesonide for the treatment of respiratory disorders