PL381564A1 - Sposób wytwarzania zasadniczo czystej odmiany polimorficznej I olanzapiny - Google Patents
Sposób wytwarzania zasadniczo czystej odmiany polimorficznej I olanzapinyInfo
- Publication number
- PL381564A1 PL381564A1 PL381564A PL38156407A PL381564A1 PL 381564 A1 PL381564 A1 PL 381564A1 PL 381564 A PL381564 A PL 381564A PL 38156407 A PL38156407 A PL 38156407A PL 381564 A1 PL381564 A1 PL 381564A1
- Authority
- PL
- Poland
- Prior art keywords
- variety
- production
- manner
- basically clean
- olanzapine
- Prior art date
Links
- KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 title 1
- 229960005017 olanzapine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL381564A PL381564A1 (pl) | 2007-01-22 | 2007-01-22 | Sposób wytwarzania zasadniczo czystej odmiany polimorficznej I olanzapiny |
| PCT/PL2008/000007 WO2008091169A2 (en) | 2007-01-22 | 2008-01-22 | Process for preparation of substantially pure polymorphic form i of olanzapine |
| US12/523,983 US20100137581A1 (en) | 2007-01-22 | 2008-01-22 | Process for preparation of substantially pure polymorphic form i of olanzapine |
| EP08705166A EP2114956A2 (en) | 2007-01-22 | 2008-01-22 | Process for preparation of substantially pure polymorphic form i of olanzapine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL381564A PL381564A1 (pl) | 2007-01-22 | 2007-01-22 | Sposób wytwarzania zasadniczo czystej odmiany polimorficznej I olanzapiny |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL381564A1 true PL381564A1 (pl) | 2008-08-04 |
Family
ID=39644968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL381564A PL381564A1 (pl) | 2007-01-22 | 2007-01-22 | Sposób wytwarzania zasadniczo czystej odmiany polimorficznej I olanzapiny |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20100137581A1 (pl) |
| EP (1) | EP2114956A2 (pl) |
| PL (1) | PL381564A1 (pl) |
| WO (1) | WO2008091169A2 (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8106188B2 (en) | 2006-06-01 | 2012-01-31 | Aurobindo Pharma Ltd | Process for preparing olanzapine form I |
| CN110964035A (zh) * | 2019-12-06 | 2020-04-07 | 北大医药股份有限公司 | 一种将奥氮平母液进行清洁回收的工业化方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9009229D0 (en) | 1990-04-25 | 1990-06-20 | Lilly Industries Ltd | Pharmaceutical compounds |
| US5637584A (en) * | 1995-03-24 | 1997-06-10 | Eli Lilly And Company | Solvate of olanzapine |
| EG23659A (en) | 1995-03-24 | 2007-03-26 | Lilly Co Eli | Process and crystal forms of methyl-thieno-benzodiazepine |
| JPH11506096A (ja) | 1995-05-30 | 1999-06-02 | イーライ・リリー・アンド・カンパニー | 認識機能不全を処置する方法 |
| JP2001517684A (ja) * | 1997-09-30 | 2001-10-09 | イーライ・リリー・アンド・カンパニー | 性機能不全を処置するための方法 |
| US6348458B1 (en) * | 1999-12-28 | 2002-02-19 | U & I Pharmaceuticals Ltd. | Polymorphic forms of olanzapine |
| DE60019461T2 (de) * | 1999-12-28 | 2005-09-22 | Cipla Ltd., Bombay | Neue polymorphe formen von olanzapin |
| SK2502003A3 (en) * | 2000-08-31 | 2004-03-02 | Reddys Lab Ltd Dr | Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine |
| PL196814B1 (pl) * | 2002-05-17 | 2008-02-29 | Inst Farmaceutyczny | Sposób wytwarzania odmiany polimorficznej I olanzapiny i jej solwaty |
| ATE500258T1 (de) * | 2002-05-31 | 2011-03-15 | Sandoz Ag | Verfahren zur herstellung von olanzapin form i |
| PL202856B1 (pl) * | 2002-12-20 | 2009-07-31 | Adamed Spo & Lstrok Ka Z Ogran | Sposób otrzymywania farmaceutycznie czystej polimorficznej postaci I olanzapiny |
| AR048272A1 (es) * | 2004-03-18 | 2006-04-12 | Lek Pharmaceuticals | Sintesis de 2 metil - 4- (4- metil -1- piperazinil) - 10 h- tieno ( 2,3-b) (1,5) benzodiazepina y sus sales, metodos para su preparacion, composiciones farmaceuticas que la contienen y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades mentales. |
| WO2005107375A2 (en) * | 2004-05-06 | 2005-11-17 | Matrix Laboratories Ltd | Process for the preparation of olanzapine form-i |
| EP2264016B1 (en) * | 2004-07-14 | 2013-05-01 | Jubilant Organosys Limited | A process for producing pure form form of 2-Methyl-4-(4-Methyl-1-Piperazinyl)-10h-thieno[2,3-B][1,5] benzodiazepine |
| SI21850A (sl) * | 2004-07-28 | 2006-02-28 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Soli olanzapina in njihova pretvorba v prosto bazo olanzapina |
-
2007
- 2007-01-22 PL PL381564A patent/PL381564A1/pl not_active Application Discontinuation
-
2008
- 2008-01-22 WO PCT/PL2008/000007 patent/WO2008091169A2/en not_active Ceased
- 2008-01-22 US US12/523,983 patent/US20100137581A1/en not_active Abandoned
- 2008-01-22 EP EP08705166A patent/EP2114956A2/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008091169A2 (en) | 2008-07-31 |
| WO2008091169A3 (en) | 2009-02-05 |
| US20100137581A1 (en) | 2010-06-03 |
| EP2114956A2 (en) | 2009-11-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |