PL3866767T3 - Kompozycja farmaceutyczna do podawania doustnego zawierająca pochodną aminopirymidyny lub jej sól - Google Patents

Kompozycja farmaceutyczna do podawania doustnego zawierająca pochodną aminopirymidyny lub jej sól

Info

Publication number: PL3866767T3
Authority: PL; Poland
Prior art keywords: salt; pharmaceutical composition; oral administration; aminopyrimidine derivative; aminopyrimidine
Prior art date: 2018-10-18

Application number

PL19872427.0T

Other languages

English (en)

Inventor

Seongkyu Kim

Deokkyu LEE

Soo-Won Kim

Jun-Mo Yang

Yoong-Sik Park

Original Assignee

Yuhan Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-10-18

Filing date

2019-10-17

Publication date

2024-04-02

2019-10-17 Application filed by Yuhan Corporation filed Critical Yuhan Corporation

2024-04-02 Publication of PL3866767T3 publication Critical patent/PL3866767T3/pl

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A61P37/00—Drugs for immunological or allergic disorders
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Immunology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Physiology (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Physical Education & Sports Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Oncology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Communicable Diseases (AREA)
Hematology (AREA)
Dermatology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Psychology (AREA)

PL19872427.0T 2018-10-18 2019-10-17 Kompozycja farmaceutyczna do podawania doustnego zawierająca pochodną aminopirymidyny lub jej sól PL3866767T3 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
KR1020180124171A KR20200043618A (ko)	2018-10-18	2018-10-18	아미노피리미딘 유도체 또는 이의 염을 포함하는 경구투여용 약학 조성물
PCT/IB2019/058862 WO2020079637A1 (en)	2018-10-18	2019-10-17	Pharmaceutical composition for oral administration comprising aminopyrimidine derivative or its salt

Publications (1)

Publication Number	Publication Date
PL3866767T3 true PL3866767T3 (pl)	2024-04-02

Family

ID=70282933

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL19872427.0T PL3866767T3 (pl)	2018-10-18	2019-10-17	Kompozycja farmaceutyczna do podawania doustnego zawierająca pochodną aminopirymidyny lub jej sól

Country Status (31)

Country	Link
US (1)	US12318390B2 (pl)
EP (2)	EP4306113A3 (pl)
JP (2)	JP7369769B2 (pl)
KR (3)	KR20200043618A (pl)
CN (2)	CN113015521B (pl)
AR (1)	AR117655A1 (pl)
AU (2)	AU2019360446B2 (pl)
BR (1)	BR112021007061A2 (pl)
CA (1)	CA3116652A1 (pl)
DK (1)	DK3866767T3 (pl)
EA (1)	EA202191061A1 (pl)
ES (1)	ES2968966T3 (pl)
FI (1)	FI3866767T3 (pl)
HR (1)	HRP20231670T1 (pl)
HU (1)	HUE065389T2 (pl)
IL (1)	IL282163B2 (pl)
LT (1)	LT3866767T (pl)
MA (1)	MA53927B1 (pl)
MD (1)	MD3866767T2 (pl)
MX (2)	MX2021004457A (pl)
MY (1)	MY208983A (pl)
PE (1)	PE20211818A1 (pl)
PH (1)	PH12021550687A1 (pl)
PL (1)	PL3866767T3 (pl)
PT (1)	PT3866767T (pl)
RS (1)	RS65012B1 (pl)
SG (1)	SG11202103057RA (pl)
SI (1)	SI3866767T1 (pl)
SM (1)	SMT202300491T1 (pl)
TW (1)	TWI831848B (pl)
WO (1)	WO2020079637A1 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR111469A1 (es)	2017-04-21	2019-07-17	Yuhan Corp	Sal de un compuesto del derivado de aminopiridina, una forma cristalina de la misma, y un proceso para preparar la misma
PH12021552798A1 (en) *	2019-05-14	2022-09-19	Janssen Biotech Inc	Combination therapies with bispecific anti-egfr/c-met antibodies and 3rd generation egfr tyrosine kinase inhibitors
US11850248B2 (en)	2019-05-14	2023-12-26	Yuhan Corporation	Therapies with 3rd generation EGFR tyrosine kinase inhibitors
JOP20220184A1 (ar)	2020-02-12	2023-01-30	Janssen Biotech Inc	علاج مصابي السرطان ممن لديهم طفرات تخطي c-Met إكسون14
TW202207940A (zh) *	2020-04-14	2022-03-01	美商健生生物科技公司	包含胺基嘧啶衍生物或其醫藥上可接受之鹽、水合物、或溶劑化物之用於經口投予之醫藥組成物
CN117425651A (zh) *	2021-06-01	2024-01-19	杭州领业医药科技有限公司	Lazertinib甲磺酸盐的水合物晶型及其制备方法和用途
CA3228195A1 (en)	2023-05-23	2025-06-30	Janssen Biotech, Inc.	Methods for treatment of non-small cell lung cancer (nsclc)
WO2025052273A1 (en)	2023-09-05	2025-03-13	Janssen Biotech, Inc.	Methods of treating non-small cell lung cancer
WO2025206726A1 (ko) *	2024-03-26	2025-10-02	(주)신테카바이오	레이저티닙(lazertinib) 또는 이의 약학적으로 허용가능한 염을 포함하는 우울증 또는 불안증 관련 질환의 예방 또는 치료용 약학 조성물
WO2026042017A1 (en)	2024-08-19	2026-02-26	Janssen Biotech, Inc.	Amivantamab in combination with lazertinib for the treatment of non-small cell lung cancer (nsclc)

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUP0103000A3 (en)	1998-07-20	2002-08-28	Smithkline Beecham Corp	Bioenhanced formulations comprising eprosartan in oral solid dosage form and process for their preparation
DE10319450A1 (de)	2003-04-30	2004-11-18	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pharmazeutische Formulierung des Telmisartan Natriumsalzes
ES2359377T3 (es) *	2006-10-27	2011-05-23	Fmc Corporation	Celulosa microcristalina coprocesada y alcohol de azúcar como excipiente para formulaciones de comprimidos.
ATE493972T1 (de)	2006-10-27	2011-01-15	Fmc Corp	Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen
US11453646B2 (en) *	2011-07-27	2022-09-27	Cornell University	Methods for RNA detection and quantification
WO2013040120A1 (en)	2011-09-14	2013-03-21	Celgene Corporation	Formulations of cyclopropanecarboxylic acid {2-(1s)-1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-3-oxo-2,3-dihydro-1h-isoindol-4-yl}-amidecelgene corporation state of incorporation:delaware
JP5899327B2 (ja)	2011-11-29	2016-04-06	ギリアドファーマセットエルエルシー	Ｃ型肝炎ウイルスを処置するための組成物および方法
WO2014175986A2 (en) *	2013-04-23	2014-10-30	RevOrtho LLC	A method and system for modular hip resurfacing
GB201400034D0 (en)	2014-01-02	2014-02-19	Astrazeneca Ab	Pharmaceutical Compositions comprising AZD9291
PT3604294T (pt)	2014-10-13	2021-07-29	Yuhan Corp	Compostos e composições para modular atividades da cinase do mutante de egfr
SG11201704827UA (en)	2014-12-16	2017-07-28	Signal Pharm Llc	Formulations of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methycyclohexylamino)-pyrimidine-5-carboxamide
CN104788427B (zh)	2015-02-05	2017-05-31	上海泓博智源医药股份有限公司	3‑(2‑嘧啶氨基)苯基丙烯酰胺类化合物及其应用
WO2016189435A1 (en)	2015-05-22	2016-12-01	Novartis Ag	Pharmaceutical compositions
WO2017061621A1 (ja)	2015-10-07	2017-04-13	協和発酵キリン株式会社	アリールアルキルアミン化合物含有医薬組成物
MX384929B (es)	2016-04-07	2025-03-14	Chemocentryx Inc	Reducción de carga tumoral mediante administración de antagonistas de ccr1 en combinación con inhibidores de muerte-1 programada (pd-1) o inhibidores de ligando-1 de muerte-1 programada (pd-l1).
AR111469A1 (es) *	2017-04-21	2019-07-17	Yuhan Corp	Sal de un compuesto del derivado de aminopiridina, una forma cristalina de la misma, y un proceso para preparar la misma
TW202207940A (zh) *	2020-04-14	2022-03-01	美商健生生物科技公司	包含胺基嘧啶衍生物或其醫藥上可接受之鹽、水合物、或溶劑化物之用於經口投予之醫藥組成物

2018
- 2018-10-18 KR KR1020180124171A patent/KR20200043618A/ko active Pending
2019
- 2019-10-17 MY MYPI2021002062A patent/MY208983A/en unknown
- 2019-10-17 CN CN201980068641.1A patent/CN113015521B/zh active Active
- 2019-10-17 SM SM20230491T patent/SMT202300491T1/it unknown
- 2019-10-17 JP JP2021520564A patent/JP7369769B2/ja active Active
- 2019-10-17 PE PE2021000495A patent/PE20211818A1/es unknown
- 2019-10-17 HR HRP20231670TT patent/HRP20231670T1/hr unknown
- 2019-10-17 LT LTEPPCT/IB2019/058862T patent/LT3866767T/lt unknown
- 2019-10-17 EP EP23211951.1A patent/EP4306113A3/en active Pending
- 2019-10-17 MX MX2021004457A patent/MX2021004457A/es unknown
- 2019-10-17 DK DK19872427.0T patent/DK3866767T3/da active
- 2019-10-17 ES ES19872427T patent/ES2968966T3/es active Active
- 2019-10-17 SG SG11202103057RA patent/SG11202103057RA/en unknown
- 2019-10-17 MA MA53927A patent/MA53927B1/fr unknown
- 2019-10-17 IL IL282163A patent/IL282163B2/en unknown
- 2019-10-17 AU AU2019360446A patent/AU2019360446B2/en active Active
- 2019-10-17 EA EA202191061A patent/EA202191061A1/ru unknown
- 2019-10-17 PL PL19872427.0T patent/PL3866767T3/pl unknown
- 2019-10-17 KR KR1020257002203A patent/KR20250025475A/ko active Pending
- 2019-10-17 RS RS20231252A patent/RS65012B1/sr unknown
- 2019-10-17 MD MDE20210799T patent/MD3866767T2/ro unknown
- 2019-10-17 BR BR112021007061-3A patent/BR112021007061A2/pt unknown
- 2019-10-17 TW TW108137395A patent/TWI831848B/zh active
- 2019-10-17 US US17/285,161 patent/US12318390B2/en active Active
- 2019-10-17 PT PT198724270T patent/PT3866767T/pt unknown
- 2019-10-17 HU HUE19872427A patent/HUE065389T2/hu unknown
- 2019-10-17 CN CN202411659054.9A patent/CN119523922A/zh active Pending
- 2019-10-17 FI FIEP19872427.0T patent/FI3866767T3/fi active
- 2019-10-17 KR KR1020217014600A patent/KR102760314B1/ko active Active
- 2019-10-17 EP EP19872427.0A patent/EP3866767B1/en active Active
- 2019-10-17 CA CA3116652A patent/CA3116652A1/en active Pending
- 2019-10-17 WO PCT/IB2019/058862 patent/WO2020079637A1/en not_active Ceased
- 2019-10-17 SI SI201930673T patent/SI3866767T1/sl unknown
- 2019-10-18 AR ARP190102972A patent/AR117655A1/es unknown
2021
- 2021-03-25 PH PH12021550687A patent/PH12021550687A1/en unknown
- 2021-04-16 MX MX2023014946A patent/MX2023014946A/es unknown
2023
- 2023-10-16 JP JP2023177976A patent/JP2024016052A/ja not_active Withdrawn
2024
- 2024-09-02 AU AU2024216519A patent/AU2024216519B2/en active Active

Also Published As

Publication number	Publication date
SG11202103057RA (en)	2021-05-28
JP2024016052A (ja)	2024-02-06
FI3866767T3 (fi)	2024-01-30
IL282163B1 (en)	2025-05-01
CN119523922A (zh)	2025-02-28
AU2019360446A1 (en)	2021-04-22
EP4306113A2 (en)	2024-01-17
CN113015521B (zh)	2025-05-13
WO2020079637A9 (en)	2020-07-23
US20210322428A1 (en)	2021-10-21
IL282163A (en)	2021-05-31
WO2020079637A1 (en)	2020-04-23
EP4306113A3 (en)	2024-02-14
PT3866767T (pt)	2024-01-18
KR20210061457A (ko)	2021-05-27
SMT202300491T1 (it)	2024-01-10
BR112021007061A2 (pt)	2021-07-20
IL282163B2 (en)	2025-09-01
SI3866767T1 (sl)	2024-02-29
TWI831848B (zh)	2024-02-11
MX2021004457A (es)	2021-07-07
AU2019360446B2 (en)	2024-09-19
MY208983A (en)	2025-06-14
CA3116652A1 (en)	2020-04-23
AR117655A1 (es)	2021-08-25
EP3866767A4 (en)	2022-07-20
ES2968966T3 (es)	2024-05-14
HUE065389T2 (hu)	2024-05-28
US12318390B2 (en)	2025-06-03
AU2024216519B2 (en)	2025-11-20
DK3866767T3 (da)	2024-01-29
JP7369769B2 (ja)	2023-10-26
MD3866767T2 (ro)	2024-06-30
PH12021550687A1 (en)	2022-02-14
RS65012B1 (sr)	2024-01-31
PE20211818A1 (es)	2021-09-14
MX2023014946A (es)	2024-02-20
CN113015521A (zh)	2021-06-22
JP2022504943A (ja)	2022-01-13
EP3866767B1 (en)	2023-11-29
MA53927B1 (fr)	2023-12-29
TW202034903A (zh)	2020-10-01
LT3866767T (lt)	2023-12-27
HRP20231670T1 (hr)	2024-03-15
MA53927A (fr)	2021-09-15
EP3866767A1 (en)	2021-08-25
AU2024216519A1 (en)	2024-09-19
KR102760314B1 (ko)	2025-02-03
NZ774402A (en)	2024-08-30
EA202191061A1 (ru)	2021-07-09
KR20200043618A (ko)	2020-04-28
KR20250025475A (ko)	2025-02-21

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