ATE493972T1 - Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen - Google Patents

Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen

Info

Publication number
ATE493972T1
ATE493972T1 AT07852968T AT07852968T ATE493972T1 AT E493972 T1 ATE493972 T1 AT E493972T1 AT 07852968 T AT07852968 T AT 07852968T AT 07852968 T AT07852968 T AT 07852968T AT E493972 T1 ATE493972 T1 AT E493972T1
Authority
AT
Austria
Prior art keywords
sugar alcohol
microcrystalline cellulose
excipient
tablet formulations
jointly processed
Prior art date
Application number
AT07852968T
Other languages
English (en)
Inventor
Jian-Xin Li
Brian Carlin
Thomas Ruszkay
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Application granted granted Critical
Publication of ATE493972T1 publication Critical patent/ATE493972T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT07852968T 2006-10-27 2007-10-26 Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen ATE493972T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85506606P 2006-10-27 2006-10-27
US85510606P 2006-10-27 2006-10-27
US92816607P 2007-05-08 2007-05-08
PCT/US2007/022685 WO2008057267A2 (en) 2006-10-27 2007-10-26 Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations

Publications (1)

Publication Number Publication Date
ATE493972T1 true ATE493972T1 (de) 2011-01-15

Family

ID=39317157

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07852968T ATE493972T1 (de) 2006-10-27 2007-10-26 Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen

Country Status (7)

Country Link
US (3) US8932629B2 (de)
EP (2) EP2076249A2 (de)
JP (2) JP2010507676A (de)
AT (1) ATE493972T1 (de)
DE (1) DE602007011792D1 (de)
TW (2) TW200826976A (de)
WO (2) WO2008057266A2 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7879382B2 (en) * 2005-09-30 2011-02-01 Fmc Corporation Stabilizers and compositions and products comprising same
ATE493972T1 (de) * 2006-10-27 2011-01-15 Fmc Corp Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen
EP2100595A1 (de) * 2008-03-10 2009-09-16 The Procter and Gamble Company Komprimierte Tabletten
JP2010024156A (ja) * 2008-07-16 2010-02-04 Ucb Pharma Sa レベチラセタムを含む医薬組成物
EP2168573A1 (de) * 2008-09-30 2010-03-31 LEK Pharmaceuticals D.D. Zubereitungen enthaltend Ezetimib
SG171752A1 (en) * 2008-11-19 2011-07-28 Avantor Performance Mat Inc Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof
US9221963B2 (en) 2008-11-27 2015-12-29 Speciality Fibres And Materials Ltd. Absorbent material
US9144625B2 (en) 2008-11-27 2015-09-29 Speciality Fibres And Materials Ltd. Cellulose ethylsulfonate-based absorbent material
US20110293717A1 (en) * 2008-12-08 2011-12-01 Ratiopharm Gmbh Compacted moxifloxacin
EP2198857A1 (de) 2008-12-19 2010-06-23 Ratiopharm GmbH Orale dispergierbare Tablette
TW201129386A (en) 2009-11-05 2011-09-01 Fmc Corp Microcrystalline cellulose and calcium phosphate compositions useful as pharmaceutical excipients
TWI461213B (zh) * 2009-11-05 2014-11-21 Fmc Corp 作為藥物賦形劑之微晶纖維素及磷酸鈣之組合物
JP2013514814A (ja) * 2009-12-22 2013-05-02 エフ エム シー コーポレーション 食品への適用のための水分散性組成物
US8632819B2 (en) * 2009-12-22 2014-01-21 Fmc Corporation Microcrystalline cellulose and calcium carbonate compositions useful as recompactible pharmaceutical excipients
CN101822796B (zh) * 2010-03-17 2012-01-04 山西仟源制药有限公司 一种银冰含片及制备方法和应用
AT509515B1 (de) 2010-06-23 2012-10-15 Chemiefaser Lenzing Ag Verwendung von cellulose in tabletten
WO2012079679A1 (en) 2010-12-16 2012-06-21 Merck Patent Gmbh Dry granulated cell culture media
FR2970400B1 (fr) 2011-01-19 2013-02-22 Eurotab Procede de fabrication de compacts de lait
US9055757B2 (en) 2011-10-05 2015-06-16 Fmc Corporation Stabilizer composition of co-attrited microcrystalline cellulose and carboxymethylcellulose, method for making, and uses
JP6188030B2 (ja) 2011-10-05 2017-08-30 エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ 微結晶セルロースおよびカルボキシメチルセルロースの安定化剤組成物、該組成物の製造方法並びに食品製品
US9828493B2 (en) 2011-12-09 2017-11-28 Fmc Corporation Co-attrited stabilizer composition having superior gel strength
WO2014087422A1 (en) * 2012-12-03 2014-06-12 Zim Laboratories Limited Chewable milk compositions and fortified powder formulations thereof
EP2968580B1 (de) * 2013-03-12 2019-06-26 Hercules LLC Coverarbeitete silicabeschichtete polymerzusammensetzung
JP6104038B2 (ja) * 2013-05-02 2017-03-29 旭化成株式会社 結晶セルロースの複合組成物
CN105616418A (zh) * 2014-11-07 2016-06-01 江苏豪森药业集团有限公司 含有细胞周期蛋白抑制剂的药物制剂及其制备方法
CN107532379B (zh) * 2015-05-14 2020-12-22 杜邦营养美国有限公司 制造漂白的微晶纤维素的方法
US11059756B1 (en) 2015-09-29 2021-07-13 Intrepid Potash, Inc. Pelletized fertilizer and methods of preparing pelletized fertilizer
RU2019110362A (ru) 2016-10-24 2020-11-24 Пауль ГЕРТАЙС Способы и устройства для управления процессом сухой грануляции
CN107063906B (zh) * 2016-12-16 2020-01-07 中国农业科学院农产品加工研究所 粉体吸湿结块程度定量表征方法
CN107960663A (zh) * 2017-11-24 2018-04-27 南通励成生物工程有限公司 碳酸钙营养强化剂及制备方法
EP3820480A4 (de) 2018-07-11 2022-03-09 Arrys Therapeutics, Inc. Polymorphe verbindungen und verwendungen davon
WO2020011257A1 (zh) * 2018-07-12 2020-01-16 四川海思科制药有限公司 一种稠合三环γ-氨基酸衍生物的组合物及其制备
CN112584838A (zh) * 2018-08-31 2021-03-30 细胞内治疗公司 新方法
CN113260363A (zh) * 2018-09-27 2021-08-13 阿瑞斯医疗有限公司 格拉普兰特(grapiprant)单位剂型
KR20200043618A (ko) * 2018-10-18 2020-04-28 주식회사유한양행 아미노피리미딘 유도체 또는 이의 염을 포함하는 경구투여용 약학 조성물
JPWO2020090970A1 (ja) * 2018-10-31 2021-09-16 富士フイルム株式会社 抗腫瘍剤を含む医薬組成物
WO2020172075A1 (en) 2019-02-19 2020-08-27 Gilead Sciences, Inc. Solid forms of fxr agonists
EP3937908A1 (de) * 2019-03-11 2022-01-19 Gilead Sciences, Inc. Formulierungen einer verbindung und deren verwendungen
CN118206485A (zh) * 2019-05-22 2024-06-18 安吉奥斯医药品有限公司 N-(4-(4-(环丙基甲基)哌嗪-1-羰基)苯基)喹啉-8-磺酰胺的结晶盐形式
EP3999039A4 (de) * 2019-07-19 2023-06-07 The Global Alliance for TB Drug Development, Inc. Pretomanid-zusammensetzungen
MX2022004909A (es) * 2019-10-24 2022-07-12 Hanmi Pharm Ind Co Ltd Una preparación farmaceutica que comprende un derivado de amida e inhibe el crecimiento de celulas cancerígenas y un producto farmaceutico que contiene la preparación.
CN110973635B (zh) * 2019-12-26 2022-07-29 汤臣倍健股份有限公司 一种辅料组合物及益生菌片剂
TW202207940A (zh) * 2020-04-14 2022-03-01 美商健生生物科技公司 包含胺基嘧啶衍生物或其醫藥上可接受之鹽、水合物、或溶劑化物之用於經口投予之醫藥組成物
CN113477179B (zh) * 2021-06-08 2022-05-13 安徽农业大学 一种多效性生物质颗粒成型机
CN113893226B (zh) * 2021-11-16 2023-03-17 烟台万润药业有限公司 一种奥美沙坦酯片剂及其制备方法
US20230372247A1 (en) * 2022-05-17 2023-11-23 Sigachi Industries Limited Self-disintegrating excipient composition for solid oral dosage forms
CN115607518B (zh) * 2022-09-16 2024-02-06 四川制药制剂有限公司 一种磷酸特地唑胺片及其制备方法
CN119524142A (zh) * 2024-11-28 2025-02-28 江苏西典药用辅料有限公司 一种药辅改性甘露醇的制备方法

Family Cites Families (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL224413A (de) 1957-01-28
US3145146A (en) 1961-10-31 1964-08-18 Warner Lambert Pharmaceutical Modified mannitol for pharmaceutical tablets
US3146168A (en) 1962-04-10 1964-08-25 Fmc Corp Manufacture of pharmaceutical preparations containing cellulose crystallite aggregates
GB1010477A (en) 1962-05-15 1965-11-17 Fmc Corp Method of making cellulose crystallite aggregates in particulate form and product of such method
US3573058A (en) 1967-01-30 1971-03-30 Swift & Co Microcrystalline cellulose compositions co-dried with hydrocolloids
US3539365A (en) 1967-02-13 1970-11-10 Fmc Corp Dispersing and stabilizing agent comprising beta-1,4 glucan and cmc and method for its preparation
US3639169A (en) 1969-04-29 1972-02-01 Sucrest Corp Direct compression vehicles and method therefor
CH604548A5 (de) 1975-12-22 1978-09-15 Nestle Sa
US4110476A (en) 1977-01-10 1978-08-29 Johnson/Rhodes Cultured Foods, Inc. Preparation of liquid and frozen yogurt products
US4263334A (en) 1978-05-31 1981-04-21 Fmc Corporation Water dispersible cellulosic powder and method of making the same
US4264637A (en) 1979-01-17 1981-04-28 Amiel Braverman Microcrystalline cellulose in freezable-gel-confection compositions
EP0047734A1 (de) 1980-03-10 1982-03-24 Edward Mendell Co., Inc. Pharmazeutische trägerzusammensetzung und verfahren zu deren herstellung
FI71750C (fi) 1981-09-10 1987-02-09 Daicel Chem Process foer tillverkning av ett alkalisalt av karboximetylcellulosaeter.
DE3506276C1 (de) 1985-02-22 1986-04-24 Meggle Milchindustrie Gmbh & Co Kg, 8094 Reitmehring Direkttablettiermittel
US4744987A (en) 1985-03-08 1988-05-17 Fmc Corporation Coprocessed microcrystalline cellulose and calcium carbonate composition and its preparation
CA1261261A (en) * 1985-03-08 1989-09-26 Dev K. Mehra Coprocessed microcrystalline cellulose and calcium carbonate composition and its preparation
US4980193A (en) 1988-06-17 1990-12-25 Fmx Corporation Microcrystalline cellulose-based stabilizer system for dry mix instant chocolate drink
EP0458484A3 (en) 1989-05-26 1992-12-09 The Kendall Company Rubber-based adhesive tapes
US5084295A (en) 1990-02-02 1992-01-28 The Procter & Gamble Company Process for making low calorie fat-containing frozen dessert products having smooth, creamy, nongritty mouthfeel
US5082684A (en) 1990-02-05 1992-01-21 Pfizer Inc. Low-calorie fat substitute
CA2067595C (en) 1991-05-01 2002-07-30 Cheryl A. Doherty Use of hydrocolloids for formulating and processing of low fat water activity confectionery products and process
ES2133294T3 (es) 1991-09-30 1999-09-16 Asahi Chemical Ind Complejo dispersable en agua y procedimiento para su fabricacion.
CA2126441C (en) 1991-12-30 1999-12-21 David F. Erkoboni Microcrystalline cellulose spheronization composition
US5272137A (en) 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
US5286510A (en) 1992-10-07 1994-02-15 Thomas J. Lipton Co., Division Of Conopco, Inc. Fat mimetic containing salad dressing and process therefor
TW272942B (de) * 1993-02-10 1996-03-21 Takeda Pharm Industry Co Ltd
US5366742A (en) 1993-05-03 1994-11-22 Fmc Corporation Colloidal microcrystalline cellulose and barrier dispersant composition and method for manufacture
AU7355294A (en) 1993-07-26 1995-02-20 Fmc Corporation Fat-like agents for low calorie food compositions
FR2710637B1 (fr) 1993-09-28 1995-12-08 Roquette Freres Mannitol pulvérulent de friabilité modérée et son procédé de préparation.
US5505982A (en) 1994-01-28 1996-04-09 Fmc Corporation Chocolate confection
JP3666911B2 (ja) 1994-11-28 2005-06-29 旭化成ケミカルズ株式会社 水分散性微細セルロース組成物及びその製造方法
JP3076732B2 (ja) 1994-12-07 2000-08-14 株式会社ヤクルト本社 カルシウム強化飲料およびその製造法
US6106865A (en) 1995-01-09 2000-08-22 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
IL116674A (en) 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6936277B2 (en) 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US5709896A (en) 1996-06-18 1998-01-20 Fmc Corporation Reduced-fat food dispersions and method of preparing
US5605712A (en) 1995-09-29 1997-02-25 Fmc Corporation Stabilizer compositions, frozen desserts containing the same and stabilizing method
US5789004A (en) 1995-12-15 1998-08-04 Fmc Corporation Coprocessed microcrystalline cellulose stabilizer compositions, foods containing the same and stabilization method
JP3706454B2 (ja) 1996-02-02 2005-10-12 ダイセル化学工業株式会社 酸性乳飲料用安定剤および酸性乳飲料
AU718658B2 (en) 1996-04-16 2000-04-20 Bayer Aktiengesellschaft D-mannitol and its preparation
US6235947B1 (en) 1997-04-14 2001-05-22 Takeda Chemical Industries, Ltd. D-mannitol and its preparation
US6025007A (en) 1996-05-28 2000-02-15 Fmc Corporation Cellulose composition, its preparation and its use in foods
JP3497666B2 (ja) 1996-08-19 2004-02-16 旭化成ケミカルズ株式会社 微細セルロース含有酸性乳飲料
JP3871146B2 (ja) 1996-10-21 2007-01-24 理研ビタミン株式会社 肉製品用安定剤及び肉製品組成物
US5747067A (en) 1996-12-06 1998-05-05 Fmc Corporation Co-processed products
JPH10237220A (ja) 1996-12-24 1998-09-08 Asahi Chem Ind Co Ltd 水性懸濁状組成物及び水分散性乾燥組成物
US5769934A (en) 1997-01-15 1998-06-23 Fmc Corporation Method for producing microcrystalline cellulose
AU5828098A (en) 1997-01-31 1998-08-25 Fmc Corporation Texture and stabilizer composition
US6079630A (en) 1997-04-11 2000-06-27 Schroeder; Rick A. Railway grade crossing apparatus and method of installation
US6037380A (en) 1997-04-11 2000-03-14 Fmc Corporation Ultra-fine microcrystalline cellulose compositions and process
IL133347A (en) 1997-06-12 2003-11-23 Fmc Corp Ultra-fine microcrystalline cellulose compositions and process for their manufacture
JPH1146723A (ja) 1997-07-30 1999-02-23 Asahi Chem Ind Co Ltd 肉製品用の安定剤及び肉製品組成物
JPH11199517A (ja) 1997-10-31 1999-07-27 Meiji Seika Kaisha Ltd 口腔内速崩壊性錠剤
JPH11299435A (ja) 1998-04-23 1999-11-02 Japan Organo Co Ltd 乳化安定剤組成物および食品
US6475539B1 (en) 1998-05-07 2002-11-05 Abbott Laboratories Nutritionally complete low pH enteral formula
HUP0103000A3 (en) 1998-07-20 2002-08-28 Smithkline Beecham Corp Bioenhanced formulations comprising eprosartan in oral solid dosage form and process for their preparation
US6391368B1 (en) 1998-09-25 2002-05-21 Fmc Corporation Rapidly peptizable microcrystalline cellulose-based stabilizing agents
JP2000184853A (ja) 1998-12-22 2000-07-04 Yakult Honsha Co Ltd 乳脂肪含有酸性乳飲料
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
NL1011901C2 (nl) 1999-04-27 2000-10-30 Cargill Bv Werkwijze voor de verwijdering van vezelhoudende mantels van graankorrels.
US6548093B1 (en) 1999-04-29 2003-04-15 J. R. Simplot Company Process for preparing storage stable low moisture parfried potato strips
WO2001019348A1 (en) 1999-09-17 2001-03-22 Mylan Pharmaceuticals Inc. Stabilization of enalapril maleate with maleic acid
US6264981B1 (en) 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
JP3400777B2 (ja) 1999-10-27 2003-04-28 カルピス株式会社 低カロリー乳含有酸性飲料
AU6521300A (en) 1999-10-29 2001-05-14 Fmc Corporation Edible coating composition
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
AU2001273496A1 (en) 2000-07-24 2002-02-05 Boehringer Ingelheim Pharmaceuticals Inc. Apparatus and method for predicting the suitability of a substance for dry granulation by roller compaction using small sample sizes
JP4284017B2 (ja) * 2000-10-06 2009-06-24 武田薬品工業株式会社 固形製剤
JP2002125587A (ja) 2000-10-27 2002-05-08 Ina Food Ind Co Ltd 酸性蛋白安定剤及びそれが含有された酸性蛋白食品
WO2002049451A2 (en) 2000-12-18 2002-06-27 Societe Des Produits Nestle S.A. Stabilizer based on microcrystalline cellulose for drink and dressing formulations
EP1226818A1 (de) 2001-01-26 2002-07-31 Pfizer Products Inc. Arzneiform mit verbesserten kohäsiven und kompressiven Eigenschaften
US20040121006A1 (en) 2001-03-06 2004-06-24 Shoichi Narita Utilization of spray-dried powder containing sugar alcohol
WO2002071861A1 (en) 2001-03-09 2002-09-19 Unilever Plc Aerated frozen product
US6753107B2 (en) * 2001-04-27 2004-06-22 Plug Power Inc. Integrated fuel cell system
JP2002345401A (ja) 2001-05-24 2002-12-03 Sanei Gen Ffi Inc 不溶性固形分を含有する酸性乳飲料
EP1269854A1 (de) 2001-06-29 2003-01-02 Camoina Melkunic B.V. Klare Getränke auf der Basis von Milch und deren Herstellung
US6753017B2 (en) 2001-11-07 2004-06-22 Jrs Pharma Lp Process for preparing dry extracts
US7241467B2 (en) 2002-01-23 2007-07-10 Pepsico, Inc. Stabilized milk product containing juice
US7247333B2 (en) 2003-03-19 2007-07-24 Pepsico Inc. Stabilized milk product containing fruit and fruit juice
TW200403994A (en) 2002-04-04 2004-03-16 Bristol Myers Squibb Co Oral administration of EPOTHILONES
US20030203097A1 (en) 2002-04-24 2003-10-30 The Procter & Gamble Company Acidic compositions comprising protein and fiber and processes of their preparation
WO2003096976A2 (en) 2002-05-14 2003-11-27 Fmc Corporation Microcrystalline cewllulose compositions
GB0211620D0 (en) 2002-05-21 2002-07-03 Bioprogress Technology Ltd Powder compaction and enrobing
ES2199061B1 (es) * 2002-06-10 2005-02-16 Laboratorios Vita, S.A. Comprimidos bucodispersables y procedimiento para su obtencion.
GB2395413A (en) 2002-11-21 2004-05-26 Danisco Stabilised fluid composition comprising suspended particulates
US7230420B2 (en) 2003-04-17 2007-06-12 Infinitum Solutions, Inc. Magnetoresistive element lifecycle tester with temperature control
GB0322358D0 (en) 2003-09-24 2003-10-22 Bioprogress Technology Ltd Improvements in powder compaction and enrobing
WO2005030177A2 (en) 2003-09-29 2005-04-07 Cipla Limited Pharmaceutical formulation with improved stability
JP4249059B2 (ja) 2004-03-01 2009-04-02 三栄源エフ・エフ・アイ株式会社 酸性乳飲料及びその製造方法
BRPI0509103A (pt) 2004-04-05 2007-08-28 Fmc Corp estabilizantes de mcc/hidrocolóide e composições comestìveis compreendendo os mesmos
US7101585B2 (en) 2004-04-15 2006-09-05 Solae, Llc Ultra high pressure homogenization process for making a stable protein based acid beverage
JP2008513584A (ja) 2004-09-23 2008-05-01 エフ エム シー コーポレーション 被覆組成物
EP1681048A1 (de) * 2005-01-14 2006-07-19 Krka Tovarna Zdravil, D.D., Novo Mesto Im Munde zerfallende Zusammensetzungen mit Olanzapin oder Donepezil
JP5057972B2 (ja) 2005-06-07 2012-10-24 三栄源エフ・エフ・アイ株式会社 ペクチンの改質方法及びその応用
US7879382B2 (en) 2005-09-30 2011-02-01 Fmc Corporation Stabilizers and compositions and products comprising same
ATE493972T1 (de) * 2006-10-27 2011-01-15 Fmc Corp Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen

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US20080131505A1 (en) 2008-06-05
US20080213360A1 (en) 2008-09-04
WO2008057266A3 (en) 2008-11-13
DE602007011792D1 (de) 2011-02-17
JP2010507676A (ja) 2010-03-11
WO2008057267A3 (en) 2008-07-24
EP2076250A2 (de) 2009-07-08
WO2008057266A2 (en) 2008-05-15
TW200824721A (en) 2008-06-16
US20110294904A1 (en) 2011-12-01
EP2076250B1 (de) 2011-01-05
JP5410290B2 (ja) 2014-02-05
WO2008057267A2 (en) 2008-05-15
US7998505B2 (en) 2011-08-16
JP2010507677A (ja) 2010-03-11
EP2076249A2 (de) 2009-07-08
TW200826976A (en) 2008-07-01

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