PL3954225T3 - Inicjujące startery oligonukleotydowe z kapem do syntezy cząsteczek rna z kapem 5' - Google Patents

Inicjujące startery oligonukleotydowe z kapem do syntezy cząsteczek rna z kapem 5'

Info

Publication number
PL3954225T3
PL3954225T3 PL21173142.7T PL21173142T PL3954225T3 PL 3954225 T3 PL3954225 T3 PL 3954225T3 PL 21173142 T PL21173142 T PL 21173142T PL 3954225 T3 PL3954225 T3 PL 3954225T3
Authority
PL
Poland
Prior art keywords
capped
synthesizing
oligonucleotide primers
initiating
rnas
Prior art date
Application number
PL21173142.7T
Other languages
English (en)
Inventor
Richard I. Hogrefe
Alexandre Lebedev
Anton P. Mccaffrey
Dongwon Shin
Original Assignee
Trilink Biotechnologies, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58387109&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3954225(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Trilink Biotechnologies, Llc filed Critical Trilink Biotechnologies, Llc
Publication of PL3954225T3 publication Critical patent/PL3954225T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/13—Nucleic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/317—Chemical structure of the backbone with an inverted bond, e.g. a cap structure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/33—Chemical structure of the base
    • C12N2310/336—Modified G
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL21173142.7T 2015-09-21 2016-09-20 Inicjujące startery oligonukleotydowe z kapem do syntezy cząsteczek rna z kapem 5' PL3954225T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562221248P 2015-09-21 2015-09-21

Publications (1)

Publication Number Publication Date
PL3954225T3 true PL3954225T3 (pl) 2024-05-20

Family

ID=58387109

Family Applications (6)

Application Number Title Priority Date Filing Date
PL21173142.7T PL3954225T3 (pl) 2015-09-21 2016-09-20 Inicjujące startery oligonukleotydowe z kapem do syntezy cząsteczek rna z kapem 5'
PL21173278.9T PL3906789T3 (pl) 2015-09-21 2016-09-20 Inicjujące startery oligonukleotydowe z kapem do syntezy cząsteczek rna z kapem 5'
PL22190426.1T PL4140491T3 (pl) 2015-09-21 2016-09-20 Sposoby syntezy rna z kapem 5'
PL24186081.6T PL4424835T3 (pl) 2015-09-21 2016-09-20 Kompozycje i sposoby syntezy rna z kapem 5'
PL16849423T PL3352584T3 (pl) 2015-09-21 2016-09-20 Kompozycje i sposoby do syntezy rna z kapem 5’
PL22175377.5T PL4104687T3 (pl) 2015-09-21 2016-09-20 Kompozycje i sposoby syntezy cząsteczek rna z kapem 5'

Family Applications After (5)

Application Number Title Priority Date Filing Date
PL21173278.9T PL3906789T3 (pl) 2015-09-21 2016-09-20 Inicjujące startery oligonukleotydowe z kapem do syntezy cząsteczek rna z kapem 5'
PL22190426.1T PL4140491T3 (pl) 2015-09-21 2016-09-20 Sposoby syntezy rna z kapem 5'
PL24186081.6T PL4424835T3 (pl) 2015-09-21 2016-09-20 Kompozycje i sposoby syntezy rna z kapem 5'
PL16849423T PL3352584T3 (pl) 2015-09-21 2016-09-20 Kompozycje i sposoby do syntezy rna z kapem 5’
PL22175377.5T PL4104687T3 (pl) 2015-09-21 2016-09-20 Kompozycje i sposoby syntezy cząsteczek rna z kapem 5'

Country Status (21)

Country Link
US (9) US10913768B2 (pl)
EP (9) EP3906789B1 (pl)
JP (4) JP6814997B2 (pl)
KR (3) KR102670937B1 (pl)
CN (8) CN120842296A (pl)
AU (5) AU2016328645C1 (pl)
CA (2) CA2999274C (pl)
CY (1) CY1124306T1 (pl)
DK (6) DK3906789T5 (pl)
ES (6) ES2968391T3 (pl)
FI (5) FI4424835T3 (pl)
HK (1) HK1255236A1 (pl)
HR (1) HRP20211091T1 (pl)
HU (5) HUE064227T2 (pl)
LT (6) LT4104687T (pl)
PL (6) PL3954225T3 (pl)
PT (7) PT4140491T (pl)
RS (1) RS62129B1 (pl)
SI (5) SI3954225T1 (pl)
SM (1) SMT202100396T1 (pl)
WO (1) WO2017053297A1 (pl)

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EP3954225B1 (en) 2023-11-22
JP7082174B2 (ja) 2022-06-07
JP2018527015A (ja) 2018-09-20
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US20220289786A1 (en) 2022-09-15
US10494399B2 (en) 2019-12-03
PL4104687T3 (pl) 2024-05-27
LT3906789T (lt) 2024-02-12
EP4104687B1 (en) 2024-01-31
KR20230026535A (ko) 2023-02-24
SI4140491T1 (sl) 2024-01-31
DK3954225T5 (da) 2024-08-05
EP3954225A1 (en) 2022-02-16
DK4424835T3 (da) 2026-03-23
EP4276189A2 (en) 2023-11-15
LT4104687T (lt) 2024-02-26
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AU2021206780A1 (en) 2021-08-12
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HUE065331T2 (hu) 2024-05-28
SMT202100396T1 (it) 2021-09-14
PL3906789T3 (pl) 2024-05-20
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AU2016328645C1 (en) 2021-10-28
DK4104687T5 (da) 2024-07-22
US20240140982A1 (en) 2024-05-02
RS62129B1 (sr) 2021-08-31
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EP3906789B1 (en) 2023-11-22
EP3954224A1 (en) 2022-02-16
CN108366604A (zh) 2018-08-03
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AU2023229522A1 (en) 2023-09-28
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CN113584020A (zh) 2021-11-02
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DK4104687T3 (da) 2024-03-04
ES2972098T3 (es) 2024-06-11
JP2022109973A (ja) 2022-07-28
PT4104687T (pt) 2024-02-27
US20190270766A1 (en) 2019-09-05
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HK1255236A1 (zh) 2019-08-09
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EP3352584A4 (en) 2019-03-27
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EP4424835B1 (en) 2026-01-21
HUE065203T2 (hu) 2024-05-28
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US10913768B2 (en) 2021-02-09
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AU2023201915A1 (en) 2023-05-04
DK3906789T5 (da) 2024-08-05
PL4140491T3 (pl) 2024-02-26
CA2999274A1 (en) 2017-03-30
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US20210371452A1 (en) 2021-12-02
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ES3065460T3 (en) 2026-05-06
US12258369B2 (en) 2025-03-25
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CA2999274C (en) 2023-12-19
PT3906789T (pt) 2023-12-18
CN120842296A (zh) 2025-10-28
DK3352584T3 (da) 2021-07-12
US12103944B2 (en) 2024-10-01
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