PL4276189T3 - Inicjujące startery oligonukleotydowe zawierające kap do syntezy cząsteczek rna z kapem 5’ - Google Patents

Inicjujące startery oligonukleotydowe zawierające kap do syntezy cząsteczek rna z kapem 5’

Info

Publication number
PL4276189T3
PL4276189T3 PL23192203.0T PL23192203T PL4276189T3 PL 4276189 T3 PL4276189 T3 PL 4276189T3 PL 23192203 T PL23192203 T PL 23192203T PL 4276189 T3 PL4276189 T3 PL 4276189T3
Authority
PL
Poland
Prior art keywords
capped
synthesizing
oligonucleotide primers
initiating
rnas
Prior art date
Application number
PL23192203.0T
Other languages
English (en)
Inventor
Richard I. Hogrefe
Alexandre Lebedev
Anton P. Mccaffrey
Dongwon Shin
Original Assignee
Trilink Biotechnologies, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58387109&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL4276189(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Trilink Biotechnologies, Llc filed Critical Trilink Biotechnologies, Llc
Publication of PL4276189T3 publication Critical patent/PL4276189T3/pl

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/13—Nucleic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/317—Chemical structure of the backbone with an inverted bond, e.g. a cap structure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/33—Chemical structure of the base
    • C12N2310/336—Modified G
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Paints Or Removers (AREA)
PL23192203.0T 2015-09-21 2016-09-20 Inicjujące startery oligonukleotydowe zawierające kap do syntezy cząsteczek rna z kapem 5’ PL4276189T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562221248P 2015-09-21 2015-09-21

Publications (1)

Publication Number Publication Date
PL4276189T3 true PL4276189T3 (pl) 2026-06-15

Family

ID=58387109

Family Applications (7)

Application Number Title Priority Date Filing Date
PL21173142.7T PL3954225T3 (pl) 2015-09-21 2016-09-20 Inicjujące startery oligonukleotydowe z kapem do syntezy cząsteczek rna z kapem 5'
PL16849423T PL3352584T3 (pl) 2015-09-21 2016-09-20 Kompozycje i sposoby do syntezy rna z kapem 5’
PL24186081.6T PL4424835T3 (pl) 2015-09-21 2016-09-20 Kompozycje i sposoby syntezy rna z kapem 5'
PL22175377.5T PL4104687T3 (pl) 2015-09-21 2016-09-20 Kompozycje i sposoby syntezy cząsteczek rna z kapem 5'
PL21173278.9T PL3906789T3 (pl) 2015-09-21 2016-09-20 Inicjujące startery oligonukleotydowe z kapem do syntezy cząsteczek rna z kapem 5'
PL22190426.1T PL4140491T3 (pl) 2015-09-21 2016-09-20 Sposoby syntezy rna z kapem 5'
PL23192203.0T PL4276189T3 (pl) 2015-09-21 2016-09-20 Inicjujące startery oligonukleotydowe zawierające kap do syntezy cząsteczek rna z kapem 5’

Family Applications Before (6)

Application Number Title Priority Date Filing Date
PL21173142.7T PL3954225T3 (pl) 2015-09-21 2016-09-20 Inicjujące startery oligonukleotydowe z kapem do syntezy cząsteczek rna z kapem 5'
PL16849423T PL3352584T3 (pl) 2015-09-21 2016-09-20 Kompozycje i sposoby do syntezy rna z kapem 5’
PL24186081.6T PL4424835T3 (pl) 2015-09-21 2016-09-20 Kompozycje i sposoby syntezy rna z kapem 5'
PL22175377.5T PL4104687T3 (pl) 2015-09-21 2016-09-20 Kompozycje i sposoby syntezy cząsteczek rna z kapem 5'
PL21173278.9T PL3906789T3 (pl) 2015-09-21 2016-09-20 Inicjujące startery oligonukleotydowe z kapem do syntezy cząsteczek rna z kapem 5'
PL22190426.1T PL4140491T3 (pl) 2015-09-21 2016-09-20 Sposoby syntezy rna z kapem 5'

Country Status (21)

Country Link
US (9) US10913768B2 (pl)
EP (9) EP4424835B1 (pl)
JP (4) JP6814997B2 (pl)
KR (3) KR20240095306A (pl)
CN (8) CN116751827B (pl)
AU (5) AU2016328645C1 (pl)
CA (2) CA3218662A1 (pl)
CY (1) CY1124306T1 (pl)
DK (7) DK4276189T3 (pl)
ES (7) ES2972098T3 (pl)
FI (6) FI4140491T3 (pl)
HK (1) HK1255236A1 (pl)
HR (1) HRP20211091T1 (pl)
HU (5) HUE065704T2 (pl)
LT (7) LT3906789T (pl)
PL (7) PL3954225T3 (pl)
PT (7) PT3352584T (pl)
RS (1) RS62129B1 (pl)
SI (6) SI4104687T1 (pl)
SM (1) SMT202100396T1 (pl)
WO (1) WO2017053297A1 (pl)

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