PL3959213T3 - Pirymidynowe inhibitory JAK w leczeniu chorób skóry - Google Patents
Pirymidynowe inhibitory JAK w leczeniu chorób skóryInfo
- Publication number
- PL3959213T3 PL3959213T3 PL20727424.2T PL20727424T PL3959213T3 PL 3959213 T3 PL3959213 T3 PL 3959213T3 PL 20727424 T PL20727424 T PL 20727424T PL 3959213 T3 PL3959213 T3 PL 3959213T3
- Authority
- PL
- Poland
- Prior art keywords
- pyrimidine
- treatment
- skin diseases
- jak inhibitors
- jak
- Prior art date
Links
- 229940122245 Janus kinase inhibitor Drugs 0.000 title 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
- 208000017520 skin disease Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962837827P | 2019-04-24 | 2019-04-24 | |
| PCT/US2020/029466 WO2020219640A1 (en) | 2019-04-24 | 2020-04-23 | Pyrimidine jak inhibitors for the treatment of skin diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3959213T3 true PL3959213T3 (pl) | 2024-11-04 |
Family
ID=70779856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL20727424.2T PL3959213T3 (pl) | 2019-04-24 | 2020-04-23 | Pirymidynowe inhibitory JAK w leczeniu chorób skóry |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11439641B2 (pl) |
| EP (1) | EP3959213B1 (pl) |
| JP (1) | JP7482152B2 (pl) |
| AR (1) | AR118767A1 (pl) |
| CA (1) | CA3135388A1 (pl) |
| ES (1) | ES2994097T3 (pl) |
| HR (1) | HRP20241053T1 (pl) |
| HU (1) | HUE067909T2 (pl) |
| PL (1) | PL3959213T3 (pl) |
| TW (1) | TW202106681A (pl) |
| WO (1) | WO2020219640A1 (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019084383A1 (en) | 2017-10-27 | 2019-05-02 | Theravance Biopharma R&D Ip, Llc | PYRIMIDINE COMPOUNDS AS JAK KINASE INHIBITORS |
| MX2021006283A (es) * | 2018-11-30 | 2021-10-22 | Jiangsu Hansoh Pharmaceutical Group Co Ltd | Derivados heteroaromáticos para uso como regulador, método de preparación de los mismos y uso de los mismos. |
| HUE066802T2 (hu) * | 2019-04-24 | 2024-09-28 | Theravance Biopharma R&D Ip Llc | JAK kináz inhibitor észter és karbonát pirimidin vegyületek |
| CN116390922B (zh) * | 2020-10-21 | 2025-07-18 | 珠海联邦制药股份有限公司 | 硒杂环类化合物及其应用 |
| WO2022094174A1 (en) * | 2020-10-30 | 2022-05-05 | Children's Hospital Medical Center | Compositions and methods for the treatment of esophageal conditions |
| EP4696710A3 (en) * | 2021-05-03 | 2026-05-06 | Incyte Corporation | Jak1 pathway inhibitors for the treatment of prurigo nodularis |
| CN117500504A (zh) * | 2021-05-03 | 2024-02-02 | 因赛特公司 | 用于治疗结节性痒疹的鲁索替尼 |
| WO2023202706A1 (zh) * | 2022-04-21 | 2023-10-26 | 南京明德新药研发有限公司 | 硒杂环类化合物的盐型和晶型及其应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4919934A (en) | 1989-03-02 | 1990-04-24 | Richardson-Vicks Inc. | Cosmetic sticks |
| US6660731B2 (en) | 2000-09-15 | 2003-12-09 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| ES2266258T3 (es) | 2000-09-15 | 2007-03-01 | Vertex Pharmaceuticals Incorporated | Compuestos de pirazol utiles como inhibidores de proteina cinasas. |
| EP1345925B1 (en) | 2000-12-21 | 2006-05-17 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| US20070179125A1 (en) | 2005-11-16 | 2007-08-02 | Damien Fraysse | Aminopyrimidines useful as kinase inhibitors |
| MX2008016523A (es) | 2006-06-30 | 2009-01-19 | Astrazeneca Ab | Derivados de pirimidina utiles en el tratamiento de cancer. |
| EP2043651A2 (en) | 2006-07-05 | 2009-04-08 | Exelixis, Inc. | Methods of using igf1r and abl kinase modulators |
| RU2014129740A (ru) | 2011-12-22 | 2016-02-10 | Ф.Хоффманн-Ля Рош Аг | Производные 2,4-диаминопиримидина в качестве ингибиторов серин/треонин киназы |
| WO2015094803A1 (en) | 2013-12-16 | 2015-06-25 | Calitor Sciences, Llc | Substituted heteroaryl compounds and methods of use |
| NO2721710T3 (pl) | 2014-08-21 | 2018-03-31 | ||
| KR20180011272A (ko) | 2015-05-28 | 2018-01-31 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | Jak 키나제 저해제로서 나프티리딘 화합물 |
| TWI726094B (zh) | 2016-04-28 | 2021-05-01 | 美商施萬生物製藥研發Ｉｐ有限責任公司 | 作為jak激酶抑制劑之嘧啶化合物 |
| CN106588885B (zh) | 2016-11-10 | 2019-03-19 | 浙江大学 | 2-取代芳环-嘧啶类衍生物及制备和应用 |
| WO2019084383A1 (en) | 2017-10-27 | 2019-05-02 | Theravance Biopharma R&D Ip, Llc | PYRIMIDINE COMPOUNDS AS JAK KINASE INHIBITORS |
| CN111601804B (zh) | 2018-11-27 | 2024-06-04 | 江苏豪森药业集团有限公司 | 含氮杂芳类衍生物调节剂、其制备方法和应用 |
| MX2021006283A (es) | 2018-11-30 | 2021-10-22 | Jiangsu Hansoh Pharmaceutical Group Co Ltd | Derivados heteroaromáticos para uso como regulador, método de preparación de los mismos y uso de los mismos. |
| HUE066802T2 (hu) * | 2019-04-24 | 2024-09-28 | Theravance Biopharma R&D Ip Llc | JAK kináz inhibitor észter és karbonát pirimidin vegyületek |
| CN113372364B (zh) | 2020-03-10 | 2024-05-31 | 明慧医药（上海）有限公司 | 一类jak激酶抑制剂及其制备和应用 |
| CN113372351A (zh) | 2020-03-10 | 2021-09-10 | 明慧医药（杭州）有限公司 | 一类jak激酶抑制剂及其制备和应用 |
-
2020
- 2020-04-23 WO PCT/US2020/029466 patent/WO2020219640A1/en not_active Ceased
- 2020-04-23 CA CA3135388A patent/CA3135388A1/en active Pending
- 2020-04-23 US US16/856,283 patent/US11439641B2/en active Active
- 2020-04-23 PL PL20727424.2T patent/PL3959213T3/pl unknown
- 2020-04-23 HU HUE20727424A patent/HUE067909T2/hu unknown
- 2020-04-23 JP JP2021562812A patent/JP7482152B2/ja active Active
- 2020-04-23 HR HRP20241053TT patent/HRP20241053T1/hr unknown
- 2020-04-23 AR ARP200101151A patent/AR118767A1/es not_active Application Discontinuation
- 2020-04-23 ES ES20727424T patent/ES2994097T3/es active Active
- 2020-04-23 TW TW109113573A patent/TW202106681A/zh unknown
- 2020-04-23 EP EP20727424.2A patent/EP3959213B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| HUE067909T2 (hu) | 2024-11-28 |
| WO2020219640A1 (en) | 2020-10-29 |
| JP2022529371A (ja) | 2022-06-21 |
| JP7482152B2 (ja) | 2024-05-13 |
| EP3959213C0 (en) | 2024-06-05 |
| HRP20241053T1 (hr) | 2024-11-08 |
| AR118767A1 (es) | 2021-10-27 |
| CA3135388A1 (en) | 2020-10-29 |
| US20200338073A1 (en) | 2020-10-29 |
| US11439641B2 (en) | 2022-09-13 |
| EP3959213B1 (en) | 2024-06-05 |
| EP3959213A1 (en) | 2022-03-02 |
| ES2994097T3 (en) | 2025-01-17 |
| TW202106681A (zh) | 2021-02-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUE067909T2 (hu) | Pirimidin JAK-inhibitorok bõrbetegségek kezelésére | |
| IL288214A (en) | Quinazolin-4-one derivatives are useful for the treatment of braf-related diseases and disorders | |
| IL276383A (en) | Treatment of ophthalmological diseases | |
| IL288523A (en) | Compounds for the treatment of pd-l1 diseases | |
| IL279260A (en) | KDM1A inhibitors for the treatment of diseases | |
| IL291735A (en) | Heteroarylbiphenylamines for the treatment of pd-l1 diseases | |
| IL270469B1 (en) | Compounds for the prevention and treatment of diseases and their use | |
| ZA201906213B (en) | Compounds and methods for the treatment of parasitic diseases | |
| SG11202006374VA (en) | Treatment of demyelinating diseases | |
| IL282643A (en) | Soft combinations for the treatment of hematological diseases | |
| GB201805100D0 (en) | Treatment of sarcopenic diseases | |
| EP3744347A4 (en) | COMPOSITION FOR USE IN THE TREATMENT OF SKIN DISEASES | |
| IL282360A (en) | Treatment for neurological diseases | |
| PL3603621T3 (pl) | Liposomy do leczenia chorób oczu | |
| IL291146A (en) | Treatment of hidradenitis with jak inhibitors | |
| EP3883567B8 (en) | Naphthyridinone-aniline compounds for treatment of dermal disorders | |
| ZA202106250B (en) | Therapeutic uses of dulaglutide | |
| PL3761982T3 (pl) | Zastosowanie nalfurafiny w leczeniu chorób demielinizacyjnych | |
| PT3833378T (pt) | Tratamento de verrugas | |
| CA3266235A1 (en) | COMPOSITIONS AND METHODS FOR THE TREATMENT OF SKIN DISEASES | |
| GB202015959D0 (en) | Treatment of diseases involving NAD | |
| SG11202010034WA (en) | TREATMENT OF SKIN DISEASES OR DISORDERS BY DELIVERY OF ANTI-OSMRß ANTIBODY | |
| EP3755334A4 (en) | TREATMENT OF LIVER DISEASES | |
| GB201909438D0 (en) | Treatment of diseases | |
| GB2603379B (en) | Avocatin B for the treatment of diseases and conditions |