PL405540A1 - Sposób otrzymywania ksantohumolu - Google Patents

Sposób otrzymywania ksantohumolu

Info

Publication number
PL405540A1
PL405540A1 PL40554013A PL40554013A PL405540A1 PL 405540 A1 PL405540 A1 PL 405540A1 PL 40554013 A PL40554013 A PL 40554013A PL 40554013 A PL40554013 A PL 40554013A PL 405540 A1 PL405540 A1 PL 405540A1
Authority
PL
Poland
Prior art keywords
xanthohumol
obtaining
dried
collected
subject
Prior art date
Application number
PL40554013A
Other languages
English (en)
Other versions
PL223580B1 (pl
Inventor
Mariusz Gagoś
Original Assignee
Bioactive-Tech Spółka Z Ograniczoną Odpowiedzialnością
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioactive-Tech Spółka Z Ograniczoną Odpowiedzialnością filed Critical Bioactive-Tech Spółka Z Ograniczoną Odpowiedzialnością
Priority to PL405540A priority Critical patent/PL223580B1/pl
Priority to KR1020167010538A priority patent/KR102308524B1/ko
Priority to PCT/IB2014/001872 priority patent/WO2015049561A1/en
Priority to RU2016115081A priority patent/RU2655926C2/ru
Priority to SI201430570T priority patent/SI3052466T1/en
Priority to HUE14792560A priority patent/HUE037941T2/hu
Priority to US15/027,004 priority patent/US9556097B2/en
Priority to EP14792560.6A priority patent/EP3052466B1/en
Priority to HRP20180042TT priority patent/HRP20180042T1/hr
Priority to CA2926619A priority patent/CA2926619C/en
Priority to BR112016007460-2A priority patent/BR112016007460B1/pt
Priority to UAA201604939A priority patent/UA116913C2/uk
Priority to MX2016004128A priority patent/MX362188B/es
Priority to AU2014330867A priority patent/AU2014330867B2/en
Priority to PT147925606T priority patent/PT3052466T/pt
Priority to NZ719709A priority patent/NZ719709B2/en
Priority to CN201480054359.5A priority patent/CN105829275B/zh
Priority to LTEP14792560.6T priority patent/LT3052466T/lt
Priority to DK14792560.6T priority patent/DK3052466T3/en
Priority to ES14792560.6T priority patent/ES2657042T3/es
Priority to JP2016546186A priority patent/JP6396479B2/ja
Priority to MEP-2018-11A priority patent/ME02981B/me
Priority to RS20180034A priority patent/RS56756B1/sr
Publication of PL405540A1 publication Critical patent/PL405540A1/pl
Priority to IL24475516A priority patent/IL244755B/en
Priority to CL2016000784A priority patent/CL2016000784A1/es
Publication of PL223580B1 publication Critical patent/PL223580B1/pl
Priority to CY20181100075T priority patent/CY1119888T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/85—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to a chemical modification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/86—Use of additives, e.g. for stabilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/213—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C49/215—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Jellies, Jams, And Syrups (AREA)

Abstract

Przedmiotem wynalazku jest sposób otrzymywania ksantohumolu, w którym ekstrakt zawierający ksantohumol miesza się z wodą, do otrzymanej mieszaniny dodaje się roztwór soli metalu przejściowego, następnie powstały osad ksantohumolu zbiera się i suszy uzyskując ksantohumol o czystości większej niż 90%.
PL405540A 2013-10-04 2013-10-04 Sposób otrzymywania ksantohumolu o wysokiej czystości PL223580B1 (pl)

Priority Applications (26)

Application Number Priority Date Filing Date Title
PL405540A PL223580B1 (pl) 2013-10-04 2013-10-04 Sposób otrzymywania ksantohumolu o wysokiej czystości
JP2016546186A JP6396479B2 (ja) 2013-10-04 2014-09-16 キサントフモールの調製方法
AU2014330867A AU2014330867B2 (en) 2013-10-04 2014-09-16 Process for the preparation of xanthohumol
RU2016115081A RU2655926C2 (ru) 2013-10-04 2014-09-16 Способ получения ксантогумола
SI201430570T SI3052466T1 (en) 2013-10-04 2014-09-16 PROCEDURE FOR PREPARING XANTOHUMOL
HUE14792560A HUE037941T2 (hu) 2013-10-04 2014-09-16 Eljárás xantohumol elõállítására
US15/027,004 US9556097B2 (en) 2013-10-04 2014-09-16 Process for the preparation of xanthohumol
EP14792560.6A EP3052466B1 (en) 2013-10-04 2014-09-16 Process for the preparation of xanthohumol
HRP20180042TT HRP20180042T1 (hr) 2013-10-04 2014-09-16 Postupak za dobivanje ksantohumola
CA2926619A CA2926619C (en) 2013-10-04 2014-09-16 Process for the preparation of xanthohumol
BR112016007460-2A BR112016007460B1 (pt) 2013-10-04 2014-09-16 Processo para a preparação de xanthohumol
UAA201604939A UA116913C2 (uk) 2013-10-04 2014-09-16 Спосіб отримання ксантогумолу
NZ719709A NZ719709B2 (en) 2013-10-04 2014-09-16 Process for the preparation of xanthohumol
KR1020167010538A KR102308524B1 (ko) 2013-10-04 2014-09-16 잔토휴몰의 제조 공정
PT147925606T PT3052466T (pt) 2013-10-04 2014-09-16 Processo para a preparação de xantohumol
MX2016004128A MX362188B (es) 2013-10-04 2014-09-16 Proceso para preparar xanthohumol.
CN201480054359.5A CN105829275B (zh) 2013-10-04 2014-09-16 一种黄腐酚的制备方法
LTEP14792560.6T LT3052466T (lt) 2013-10-04 2014-09-16 Ksantohumolio paruošimo būdas
DK14792560.6T DK3052466T3 (en) 2013-10-04 2014-09-16 Process for the preparation of xanthohumol
ES14792560.6T ES2657042T3 (es) 2013-10-04 2014-09-16 Procedimiento para la preparación de xantohumol
PCT/IB2014/001872 WO2015049561A1 (en) 2013-10-04 2014-09-16 Process for the preparation of xanthohumol
MEP-2018-11A ME02981B (me) 2013-10-04 2014-09-16 Postupak za pripremanje ksantohumola
RS20180034A RS56756B1 (sr) 2013-10-04 2014-09-16 Postupak za pripremanje ksantohumola
IL24475516A IL244755B (en) 2013-10-04 2016-03-27 process to create xanthohumol
CL2016000784A CL2016000784A1 (es) 2013-10-04 2016-04-04 Procedimiento para la preparacion de xanthohumol ((e)-1-(2,4-dihidroxi-6-metoxi-3-(3-metilbut-2-enil)-fenil)-3-(4-hidroxifenil)-prop-2-en-1-ona)) extraido desde lúpulo (humulus lupulus)).
CY20181100075T CY1119888T1 (el) 2013-10-04 2018-01-22 Μεθοδος για την παρασκευη ξανθοχουμολης

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL405540A PL223580B1 (pl) 2013-10-04 2013-10-04 Sposób otrzymywania ksantohumolu o wysokiej czystości

Publications (2)

Publication Number Publication Date
PL405540A1 true PL405540A1 (pl) 2015-04-13
PL223580B1 PL223580B1 (pl) 2016-10-31

Family

ID=51844768

Family Applications (1)

Application Number Title Priority Date Filing Date
PL405540A PL223580B1 (pl) 2013-10-04 2013-10-04 Sposób otrzymywania ksantohumolu o wysokiej czystości

Country Status (25)

Country Link
US (1) US9556097B2 (pl)
EP (1) EP3052466B1 (pl)
JP (1) JP6396479B2 (pl)
KR (1) KR102308524B1 (pl)
CN (1) CN105829275B (pl)
AU (1) AU2014330867B2 (pl)
BR (1) BR112016007460B1 (pl)
CA (1) CA2926619C (pl)
CL (1) CL2016000784A1 (pl)
CY (1) CY1119888T1 (pl)
DK (1) DK3052466T3 (pl)
ES (1) ES2657042T3 (pl)
HR (1) HRP20180042T1 (pl)
HU (1) HUE037941T2 (pl)
IL (1) IL244755B (pl)
LT (1) LT3052466T (pl)
ME (1) ME02981B (pl)
MX (1) MX362188B (pl)
PL (1) PL223580B1 (pl)
PT (1) PT3052466T (pl)
RS (1) RS56756B1 (pl)
RU (1) RU2655926C2 (pl)
SI (1) SI3052466T1 (pl)
UA (1) UA116913C2 (pl)
WO (1) WO2015049561A1 (pl)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL422083A1 (pl) * 2017-06-30 2019-01-02 Bioactive-Tech Spółka Z Ograniczoną Odpowiedzialnością Sposób otrzymywania ksantohumolu
PL441690A1 (pl) * 2022-07-08 2024-01-15 Innox Spółka Z Ograniczoną Odpowiedzialnością Sposób izolacji i oczyszczania ksantohumolu

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020033796A1 (en) * 2018-08-10 2020-02-13 Metagenics, Inc. Method of treating inflammatory bowel disease
EP4104818A1 (en) 2021-06-17 2022-12-21 Skeye Pharma GbR Ophthalmic composition comprising xanthohumol
EP4104817A1 (en) 2021-06-17 2022-12-21 Skeye Pharma GbR Ophthalmic composition comprising astragaloside iv
EP4302767B1 (en) 2022-07-04 2024-10-02 Skeye Pharma GmbH Ophthalmic composition comprising eriocitrin for treating dry eye syndrome

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1274678A (en) 1968-11-19 1972-05-17 Bush Boake Allen Ltd Hop extracts
CN1260122A (zh) * 1999-01-08 2000-07-19 仲伟德 一种以植物为原料的杀菌剂农药
DE19939350B4 (de) 1999-08-19 2005-04-07 Plantextrakt Gmbh & Co. Kg Hopfenextrakt und Verfahren zu dessen Herstellung
DE10139479A1 (de) 2001-08-10 2003-02-27 Schwabe Willmar Gmbh & Co Hopfenextrakte, Verfahren zu ihrer Herstellung und Verwendung
DE10256031A1 (de) 2002-11-30 2004-06-09 Nateco 2 Gmbh & Co. Kg Verfahren zur Herstellung eines Xanthohumol-angereicherten Hopfenextraktes und dessen Verwendung
EP1543834A1 (en) 2003-12-16 2005-06-22 Biodynamics Production of hop extracts having oestrogenic and antiproliferative bioactivity
DE102006018988B3 (de) 2006-04-25 2007-08-09 Nateco2 Gmbh & Co. Kg Verfahren zur Herstellung eines Xanthohumol-haltigen Pulvers hoher Reinheit und dessen Verwendung
RU2344167C2 (ru) * 2007-03-12 2009-01-20 Общество с ограниченной ответственностью "Дары Кубани" Хмелевый экстракт
WO2009023710A2 (en) * 2007-08-15 2009-02-19 Flaxan Llc Xanthohumol-enriched hop extract
US8142821B2 (en) * 2007-08-15 2012-03-27 Flazan GmbH & Co. KG Xanthohumol-enriched hop extract
CN101440029A (zh) * 2008-11-04 2009-05-27 中国食品发酵工业研究院 一种从啤酒花中提取黄腐酚的方法
CN101433592B (zh) * 2008-12-12 2011-06-08 桂林莱茵生物科技股份有限公司 含黄腐酚的啤酒花提取物的制备方法
PL214468B1 (pl) 2009-05-15 2013-08-30 Univ Przyrodniczy We Wroclawiu Sposób otrzymywania ksantohumolu
CN101811950B (zh) * 2010-05-07 2013-01-30 玉门拓璞科技开发有限责任公司 高纯度黄腐酚的工业化生产方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL422083A1 (pl) * 2017-06-30 2019-01-02 Bioactive-Tech Spółka Z Ograniczoną Odpowiedzialnością Sposób otrzymywania ksantohumolu
PL242648B1 (pl) * 2017-06-30 2023-04-03 Bioactive Tech Spolka Z Ograniczona Odpowiedzialnoscia Sposób otrzymywania ksantohumolu
PL441690A1 (pl) * 2022-07-08 2024-01-15 Innox Spółka Z Ograniczoną Odpowiedzialnością Sposób izolacji i oczyszczania ksantohumolu
PL247894B1 (pl) * 2022-07-08 2025-09-15 Innox Spolka Z Ograniczona Odpowiedzialnoscia Sposób izolacji i oczyszczania ksantohumolu w procesie ekstrakcji z materiału roślinnego

Also Published As

Publication number Publication date
RU2655926C2 (ru) 2018-05-30
HRP20180042T1 (hr) 2018-02-09
CN105829275A (zh) 2016-08-03
CL2016000784A1 (es) 2016-10-07
KR20160067127A (ko) 2016-06-13
IL244755B (en) 2019-10-31
AU2014330867A1 (en) 2016-05-26
CA2926619C (en) 2021-11-23
CN105829275B (zh) 2017-09-19
ES2657042T3 (es) 2018-03-01
HUE037941T2 (hu) 2018-09-28
WO2015049561A1 (en) 2015-04-09
DK3052466T3 (en) 2018-01-22
SI3052466T1 (en) 2018-02-28
RS56756B1 (sr) 2018-04-30
LT3052466T (lt) 2018-02-12
ME02981B (me) 2018-10-20
BR112016007460B1 (pt) 2023-05-02
AU2014330867B2 (en) 2017-11-23
EP3052466A1 (en) 2016-08-10
PT3052466T (pt) 2018-01-30
JP2016535763A (ja) 2016-11-17
MX2016004128A (es) 2016-08-12
NZ719709A (en) 2020-09-25
UA116913C2 (uk) 2018-05-25
EP3052466B1 (en) 2017-10-25
MX362188B (es) 2019-01-07
RU2016115081A3 (pl) 2018-03-29
JP6396479B2 (ja) 2018-09-26
US9556097B2 (en) 2017-01-31
RU2016115081A (ru) 2017-11-10
CY1119888T1 (el) 2018-06-27
KR102308524B1 (ko) 2021-10-05
US20160237014A1 (en) 2016-08-18
BR112016007460A2 (pt) 2017-08-01
PL223580B1 (pl) 2016-10-31
CA2926619A1 (en) 2015-04-09
IL244755A0 (en) 2016-04-21

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