PL407772A1 - Crystalline form of the complex chloride trihydrate [copper (II) di(2-Amino-5-guanidynopentano)(4,4'-dipyridyl)] and a method for its preparation - Google Patents

Crystalline form of the complex chloride trihydrate [copper (II) di(2-Amino-5-guanidynopentano)(4,4'-dipyridyl)] and a method for its preparation

Info

Publication number
PL407772A1
PL407772A1 PL407772A PL40777214A PL407772A1 PL 407772 A1 PL407772 A1 PL 407772A1 PL 407772 A PL407772 A PL 407772A PL 40777214 A PL40777214 A PL 40777214A PL 407772 A1 PL407772 A1 PL 407772A1
Authority
PL
Poland
Prior art keywords
dipyridyl
amino
copper
crystalline form
guanidynopentano
Prior art date
Application number
PL407772A
Other languages
Polish (pl)
Inventor
Agnieszka Wojciechowska
Agnieszka Wojtkiewicz
Anna Barbara Gągor
Anna Jarząb
Błażej Późniak
Original Assignee
Politechnika Wrocławska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Wrocławska filed Critical Politechnika Wrocławska
Priority to PL407772A priority Critical patent/PL407772A1/en
Publication of PL407772A1 publication Critical patent/PL407772A1/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Wynalazek dotyczy krystalicznej formy kompleksu trihydrat chlorku [di(2-amino-5-guanidynopentano)(4,4'-dipirydylo)miedzi(II)] o wzorze 1 znajdują zastosowanie jako składnik preparatów przeciwgrzybiczych. Wynalazek ujawnia również sposób wytwarzania krystalicznej formy kompleksu, który polega na tym, że jedną część molową uwodnionej soli chlorku miedzi(II) poddaje się reakcji z jedną lub dwiema częściami molowymi kwasu 2-amino-5-guanidynopentanoweeeego o wzorze 3, po czym do tak utworzonej mieszaniny dodaje się rozpuszczony w alkoholu metylowym uwodniony 4,4'-dipirydyl o wzorze 4. Reakcję prowadzi się na mieszadle magnetycznym przy ciągłym mieszaniu, po czym po minimum 50 dniach otrzymuje się krystaliczną formę kompleksu trihydrat chlorku [di(2-amino-5-guanidynopentano)(4,4'-dipirydylo)miedzi(II)].The invention relates to the crystalline form of the [di (2-amino-5-guanidinopentane) (4,4'-dipyridyl) copper (II)] chloride trihydrate of formula 1, which is used as an ingredient in antifungal preparations. The invention also discloses a method for producing the crystalline form of the complex, which consists in the fact that one molar part of the hydrated copper (II) chloride is reacted with one or two molar parts of 2-amino-5-guanidinopentanoic acid of formula 3, followed by hydrated 4,4'-dipyridyl of formula 4 dissolved in methyl alcohol is added. The reaction is carried out on a magnetic stirrer with constant stirring, after which after a minimum of 50 days the crystalline form of the chloride trihydrate complex [di (2-amino-5 -guanidynopentano) (4,4'-dipyridyl), copper (II)].

PL407772A 2014-04-02 2014-04-02 Crystalline form of the complex chloride trihydrate [copper (II) di(2-Amino-5-guanidynopentano)(4,4'-dipyridyl)] and a method for its preparation PL407772A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL407772A PL407772A1 (en) 2014-04-02 2014-04-02 Crystalline form of the complex chloride trihydrate [copper (II) di(2-Amino-5-guanidynopentano)(4,4'-dipyridyl)] and a method for its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL407772A PL407772A1 (en) 2014-04-02 2014-04-02 Crystalline form of the complex chloride trihydrate [copper (II) di(2-Amino-5-guanidynopentano)(4,4'-dipyridyl)] and a method for its preparation

Publications (1)

Publication Number Publication Date
PL407772A1 true PL407772A1 (en) 2014-12-22

Family

ID=52106934

Family Applications (1)

Application Number Title Priority Date Filing Date
PL407772A PL407772A1 (en) 2014-04-02 2014-04-02 Crystalline form of the complex chloride trihydrate [copper (II) di(2-Amino-5-guanidynopentano)(4,4'-dipyridyl)] and a method for its preparation

Country Status (1)

Country Link
PL (1) PL407772A1 (en)

Similar Documents

Publication Publication Date Title
MX349969B (en) Methods of preparing nicotinamide riboside and derivatives thereof.
MX2017016363A (en) Halogen-substituted phenoxyphenylamidines and the use thereof as fungicides.
EP3733717A3 (en) An improved process for the preparation of sugammadex
AR105292A1 (en) PHENOXIHALOGENOFENILAMIDINAS AND ITS USE AS FUNGICIDES
EA202090368A1 (en) LYSOPHOSPHATID ACID RECEPTOR COMPOUNDS 1 (LPAR1)
EP4410773A3 (en) Process for the synthesis of (s) 3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid
ZA201805790B (en) Improved process for the preparation of osimertinib (azd9291) or a salt thereof, and "azd9291 aniline" or a salt thereof
MX2021006692A (en) Improved process for preparing ozanimod.
MX2018007982A (en) Process for preparing 1,1,3-trioxo-1,2-benzothiazole-6-carboxamid e.
MY140618A (en) Method for preparing acid addition salts of polyacidic basic compounds
PH12018502237A1 (en) Substituted 2-alkylimidazolyl-carboxamides as pest control agents
TN2014000329A1 (en) Method for preparing compound by novel michael addition reaction using water or various acids as additive
EA201891866A1 (en) N, N-DIMETHYL-3 - [[5- (3-METHYL-2-OXO-1-TETRAHYDROPYRAN-4-IL-IMIDAZO [4,5-c] KHINOLIN-8-IL) -2-Pyridyl] Oxy] PROPAN-1-AMINOXIDE AS AN ATOM-KINASE MODULATOR (ATAXY-TELEEGIACTASY MUTATION) FOR CANCER TREATMENT
PL410423A1 (en) Alkoxymethyl bis(2-hydroxyethyl)methylammonium 4-chloro-2-methylphenoxyacetates, method for obtaining them and application as plant pesticides
MX379419B (en) Process for preparing aminothiol ester compounds and salts thereof
PL408658A1 (en) Crystalline form of the a nitrate(V) complex of [(2-amino-5-guanidine-pentane)(mi-O,O'-nitrate(V))(2,2'-dipyridile)copper(II)] and method for producing it
MX2015011423A (en) Alkoximino-substituted anthranilic acid diamides as pesticides.
PL408655A1 (en) Crystalline form of the complex of [(2-amino-5-guanidine-pentane)di(thiocyanate)copper(II)] and method for producing it
EP4053109A4 (en) RORy REGULATOR ACID ADDITION SALT
MX2019012468A (en) Novel phenylamine compounds.
CO2018001307A2 (en) An improved process for the preparation of tetrophosmin or its acid addition salt
PL408663A1 (en) Crystalline form of the chloride trihydrate complex of [(2-amino-5-guanidine-pentane)chloro(2,2'-dipyridile)copper(II)] and method for producing it
PH12018501046A1 (en) Crystals of monovalent cation salt of 3-hydroxyisovaleric acid, and method for producing said crystals
PL403471A1 (en) The crystalline hydrate form of the complex aqua di(bis(S)-2-amino-3-(4-hydroxyphenyl)propane)copper(II) and a process for its preparation
PH12018502095A1 (en) Amorphizing agent, amorphous composition comprising amorphizing agent and utilization thereof