PL422499A1 - Method for producing 6β,11α-dihydroxyprogesterone - Google Patents

Method for producing 6β,11α-dihydroxyprogesterone

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Publication number
PL422499A1
PL422499A1 PL422499A PL42249917A PL422499A1 PL 422499 A1 PL422499 A1 PL 422499A1 PL 422499 A PL422499 A PL 422499A PL 42249917 A PL42249917 A PL 42249917A PL 422499 A1 PL422499 A1 PL 422499A1
Authority
PL
Poland
Prior art keywords
dihydroxyprogesterone
producing
kch
chloroform
organism
Prior art date
Application number
PL422499A
Other languages
Polish (pl)
Other versions
PL237127B1 (en
Inventor
Ewa Kozłowska
Jordan Sycz
Edyta Kostrzewa-Susłow
Tomasz Janeczko
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL422499A priority Critical patent/PL237127B1/en
Publication of PL422499A1 publication Critical patent/PL422499A1/en
Publication of PL237127B1 publication Critical patent/PL237127B1/en

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)

Abstract

Niniejsze zgłoszenie dotyczy sposobu wytwarzania 6β,11α-dihydroksyprogesteronu o wzorze 2. W wyniku działania układu enzymatycznego zawartego w komórkach szczepu Isaria farinosa KCh KW1.1 następuje hydroksylacja przy nieaktywowanych atomie węgla C-6. Uzyskany w ten sposób produkt wydziela się z wodnej kultury mikroorganizmu, znanym sposobem, przez ekstrakcję rozpuszczalnikiem organicznym niemieszającym się z wodą (chloroform).The present application relates to a method for the production of 6β,11α-dihydroxyprogesterone of the formula 2. As a result of the activity of the enzyme system contained in the cells of the Isaria farinosa KCh KW1.1 strain, hydroxylation occurs at the non-activated C-6 carbon atom. The product thus obtained is isolated from the aqueous culture of the micro-organism in a known manner by extraction with a water-immiscible organic solvent (chloroform).

PL422499A 2017-08-09 2017-08-09 Method for producing 6β,11α-dihydroxyprogesterone PL237127B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL422499A PL237127B1 (en) 2017-08-09 2017-08-09 Method for producing 6β,11α-dihydroxyprogesterone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL422499A PL237127B1 (en) 2017-08-09 2017-08-09 Method for producing 6β,11α-dihydroxyprogesterone

Publications (2)

Publication Number Publication Date
PL422499A1 true PL422499A1 (en) 2019-02-11
PL237127B1 PL237127B1 (en) 2021-03-22

Family

ID=65270275

Family Applications (1)

Application Number Title Priority Date Filing Date
PL422499A PL237127B1 (en) 2017-08-09 2017-08-09 Method for producing 6β,11α-dihydroxyprogesterone

Country Status (1)

Country Link
PL (1) PL237127B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL444652A1 (en) * 2023-04-27 2024-10-28 Uniwersytet Przyrodniczy we Wrocławiu 12β,17α-Dihydroxy-pregna-1,4-diene-3,20-dione and method for producing 12β,17α-dihydroxy-pregna-1,4-diene-3,20-dione

Also Published As

Publication number Publication date
PL237127B1 (en) 2021-03-22

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