PL4081511T4 - Pochodne karboksylowe o właściwościach przeciwzapalnych - Google Patents
Pochodne karboksylowe o właściwościach przeciwzapalnychInfo
- Publication number
- PL4081511T4 PL4081511T4 PL20830293.5T PL20830293T PL4081511T4 PL 4081511 T4 PL4081511 T4 PL 4081511T4 PL 20830293 T PL20830293 T PL 20830293T PL 4081511 T4 PL4081511 T4 PL 4081511T4
- Authority
- PL
- Poland
- Prior art keywords
- carboxy derivatives
- antiinflammatory properties
- antiinflammatory
- properties
- carboxy
- Prior art date
Links
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19219531 | 2019-12-23 | ||
| EP20162545 | 2020-03-11 | ||
| EP20189623 | 2020-08-05 | ||
| EP20205768 | 2020-11-04 | ||
| PCT/GB2020/053357 WO2021130492A1 (en) | 2019-12-23 | 2020-12-23 | Carboxy derivatives with antiinflammatory properties |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL4081511T3 PL4081511T3 (pl) | 2024-11-25 |
| PL4081511T4 true PL4081511T4 (pl) | 2024-12-09 |
Family
ID=74104118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL20830293.5T PL4081511T4 (pl) | 2019-12-23 | 2020-12-23 | Pochodne karboksylowe o właściwościach przeciwzapalnych |
Country Status (29)
| Country | Link |
|---|---|
| EP (2) | EP4081511B3 (pl) |
| JP (2) | JP7679384B2 (pl) |
| KR (1) | KR20220119425A (pl) |
| CN (1) | CN115066418B (pl) |
| AU (1) | AU2020412853A1 (pl) |
| BR (1) | BR112022011933A2 (pl) |
| CA (2) | CA3161424C (pl) |
| CL (1) | CL2022001722A1 (pl) |
| CO (1) | CO2022008652A2 (pl) |
| CR (1) | CR20220300A (pl) |
| DK (1) | DK4081511T3 (pl) |
| EC (1) | ECSP22049370A (pl) |
| ES (1) | ES2987014T3 (pl) |
| FI (1) | FI4081511T3 (pl) |
| HR (1) | HRP20241378T1 (pl) |
| HU (1) | HUE068571T2 (pl) |
| IL (1) | IL293982B2 (pl) |
| JO (1) | JOP20220162A1 (pl) |
| LT (1) | LT4081511T (pl) |
| MA (1) | MA58170B1 (pl) |
| MD (1) | MD4081511T2 (pl) |
| MX (1) | MX2022007846A (pl) |
| PE (1) | PE20221584A1 (pl) |
| PH (1) | PH12022551546A1 (pl) |
| PL (1) | PL4081511T4 (pl) |
| RS (1) | RS66019B1 (pl) |
| SI (1) | SI4081511T1 (pl) |
| TW (1) | TWI891696B (pl) |
| WO (1) | WO2021130492A1 (pl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2021013299A (es) | 2019-04-30 | 2022-01-31 | Sitryx Therapeutics Ltd | Derivados de acido itaconico y usos de estos en el tratamiento de una enfermedad inflamatoria asociada con una respuesta inmunitaria indeseable. |
| WO2020232247A1 (en) | 2019-05-14 | 2020-11-19 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
| IL298999A (en) | 2020-06-11 | 2023-02-01 | Provention Bio Inc | Methods and compositions for the prevention of type 1 diabetes |
| EP4192821A1 (en) | 2020-08-05 | 2023-06-14 | Sitryx Therapeutics Limited | Alpha,beta unsaturated methacrylic esters with anti-inflammatory properties |
| EP4330231A1 (en) * | 2021-04-26 | 2024-03-06 | Sitryx Therapeutics Limited | 2-methylene-4-oxo-butanoic acid drivatives for the treatment of inflammation |
| JP2024520444A (ja) | 2021-05-24 | 2024-05-24 | プロヴェンション・バイオ・インコーポレイテッド | １型糖尿病を治療するための方法 |
| EP4359390A1 (en) * | 2021-06-22 | 2024-05-01 | Sitryx Therapeutics Limited | Acrylamide derivatives useful as anti-inflammatory agents |
| CN113499453B (zh) * | 2021-07-20 | 2022-10-21 | 徐州医科大学 | 自噬抑制及抗炎联合温合光热诊疗剂及其制备方法与应用 |
| US20240360067A1 (en) | 2021-08-11 | 2024-10-31 | Sitryx Therapeutics Limited | Derivatives of itaconic acid and their use as anti-inflammatory agents |
| AU2023287566A1 (en) | 2022-06-22 | 2025-01-16 | Sitryx Therapeutics Limited | Oxadiazole derivatives, preparation process thereof and their use in treating inflammatory diseases |
| WO2024089421A1 (en) | 2022-10-25 | 2024-05-02 | Sitryx Therapeutics Limited | Tetrazole derivatives |
| CN120712258A (zh) | 2022-12-15 | 2025-09-26 | 西特瑞治疗有限公司 | 用于治疗或预防炎性疾病或与不良免疫反应相关的疾病的取代吡啶类化合物 |
| KR102864655B1 (ko) * | 2023-01-19 | 2025-09-29 | 대한민국 | 뎅기바이러스 감염에 의한 질환의 예방 또는 치료용 약학적 조성물 |
| CN115819186B (zh) * | 2023-02-14 | 2023-05-16 | 广东银珠医药科技有限公司 | 一种3,5-二氯苯甲醇的新型制备方法 |
| CN117205194A (zh) * | 2023-05-10 | 2023-12-12 | 苏州大学 | 衣康酸或其衍生物在制备预防或治疗急性移植物抗宿主病药物中的应用 |
| CN116725998A (zh) * | 2023-07-20 | 2023-09-12 | 中国科学技术大学 | 特立氟胺在抑制nlrp3炎症小体活化中的应用 |
| CN119792264B (zh) * | 2025-03-14 | 2025-06-10 | 华中科技大学同济医学院附属同济医院 | 丁酰肼在制备预防或治疗copd的药物中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995011235A1 (en) * | 1993-10-20 | 1995-04-27 | The Upjohn Company | Pyrimidinones as antiarthritic and anti-inflammatories |
| US6566384B1 (en) * | 1996-08-07 | 2003-05-20 | Darwin Discovery Ltd. | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity |
| TW201206429A (en) * | 2010-07-08 | 2012-02-16 | Merck Serono Sa | Substituted oxadiazole derivatives |
| KR101861883B1 (ko) * | 2010-12-06 | 2018-05-28 | 글락소 그룹 리미티드 | Lp-PLA₂에 의해 매개되는 질환 또는 상태의 치료에 사용하기 위한 피리미디논 화합물 |
| KR102085557B1 (ko) | 2013-03-14 | 2020-03-06 | 엘커메스 파마 아일랜드 리미티드 | 푸마레이트의 프로드럭 및 다양한 질환을 치료하는데 있어서의 이들의 용도 |
| WO2014152263A1 (en) * | 2013-03-15 | 2014-09-25 | Karyopharm Therapeutics Inc. | Exo olefin-containing nuclear transport modulators and uses thereof |
| AU2014290368B2 (en) * | 2013-07-18 | 2019-07-11 | Baylor College Of Medicine | Methods and compositions for treatment of muscle wasting, muscle weakness, and/or cachexia |
| CN103923105B (zh) * | 2014-04-17 | 2016-08-24 | 北京大学 | 2-中氮茚甲酰胺类化合物及其制备和用途 |
| EP3416634A4 (en) | 2016-02-15 | 2019-10-09 | Artyomov, Maxim | IMMUNOMODULATORY AGENTS AND METHOD FOR USE THEREOF |
| WO2019036509A1 (en) | 2017-08-14 | 2019-02-21 | Washington University | METHODS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH CANCER, INFLAMMATION OR IMMUNE RESPONSE |
| CN110731955B (zh) | 2019-10-28 | 2023-05-02 | 中山大学 | 衣康酸二甲酯在预防和治疗溃疡性结肠炎及其癌变中的应用 |
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2020
- 2020-12-23 MX MX2022007846A patent/MX2022007846A/es unknown
- 2020-12-23 EP EP20830293.5A patent/EP4081511B3/en active Active
- 2020-12-23 CR CR20220300A patent/CR20220300A/es unknown
- 2020-12-23 TW TW109145642A patent/TWI891696B/zh active
- 2020-12-23 LT LTEPPCT/GB2020/053357T patent/LT4081511T/lt unknown
- 2020-12-23 CA CA3161424A patent/CA3161424C/en active Active
- 2020-12-23 PH PH1/2022/551546A patent/PH12022551546A1/en unknown
- 2020-12-23 MD MDE20221214T patent/MD4081511T2/ro unknown
- 2020-12-23 MA MA58170A patent/MA58170B1/fr unknown
- 2020-12-23 AU AU2020412853A patent/AU2020412853A1/en active Pending
- 2020-12-23 JP JP2022538727A patent/JP7679384B2/ja active Active
- 2020-12-23 SI SI202030480T patent/SI4081511T1/sl unknown
- 2020-12-23 IL IL293982A patent/IL293982B2/en unknown
- 2020-12-23 DK DK20830293.5T patent/DK4081511T3/da active
- 2020-12-23 KR KR1020227024819A patent/KR20220119425A/ko active Pending
- 2020-12-23 CN CN202080083315.0A patent/CN115066418B/zh active Active
- 2020-12-23 RS RS20241087A patent/RS66019B1/sr unknown
- 2020-12-23 PE PE2022001159A patent/PE20221584A1/es unknown
- 2020-12-23 HU HUE20830293A patent/HUE068571T2/hu unknown
- 2020-12-23 EP EP24183456.3A patent/EP4442319A3/en not_active Withdrawn
- 2020-12-23 ES ES20830293T patent/ES2987014T3/es active Active
- 2020-12-23 CA CA3280359A patent/CA3280359A1/en active Pending
- 2020-12-23 FI FIEP20830293.5T patent/FI4081511T3/fi active
- 2020-12-23 WO PCT/GB2020/053357 patent/WO2021130492A1/en not_active Ceased
- 2020-12-23 BR BR112022011933A patent/BR112022011933A2/pt unknown
- 2020-12-23 HR HRP20241378TT patent/HRP20241378T1/hr unknown
- 2020-12-23 PL PL20830293.5T patent/PL4081511T4/pl unknown
-
2022
- 2022-06-21 CO CONC2022/0008652A patent/CO2022008652A2/es unknown
- 2022-06-21 EC ECSENADI202249370A patent/ECSP22049370A/es unknown
- 2022-06-21 JO JOP/2022/0162A patent/JOP20220162A1/ar unknown
- 2022-06-22 CL CL2022001722A patent/CL2022001722A1/es unknown
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2025
- 2025-05-07 JP JP2025077120A patent/JP2025131581A/ja active Pending
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