PL418653A1 - 1'2'-Di[3,7,11-trimethyl-3-vinyldodeca-6,10-dienyl]-sn-glycero-3'-phosphocholine and method for obtaining 1'2'-di[3,7,11-trimethyl-3-vinyldodeca-6,10-dienyl]-sn-glycero-3'-phosphocholine - Google Patents

1'2'-Di[3,7,11-trimethyl-3-vinyldodeca-6,10-dienyl]-sn-glycero-3'-phosphocholine and method for obtaining 1'2'-di[3,7,11-trimethyl-3-vinyldodeca-6,10-dienyl]-sn-glycero-3'-phosphocholine

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Publication number
PL418653A1
PL418653A1 PL418653A PL41865316A PL418653A1 PL 418653 A1 PL418653 A1 PL 418653A1 PL 418653 A PL418653 A PL 418653A PL 41865316 A PL41865316 A PL 41865316A PL 418653 A1 PL418653 A1 PL 418653A1
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PL
Poland
Prior art keywords
phosphocholine
glycero
trimethyl
vinyldodeca
dienyl
Prior art date
Application number
PL418653A
Other languages
Polish (pl)
Other versions
PL238119B1 (en
Inventor
Anna Gliszczyńska
Natalia Niezgoda
Witold Gładkowski
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL418653(22)20160912A priority Critical patent/PL238119B1/en
Publication of PL418653A1 publication Critical patent/PL418653A1/en
Publication of PL238119B1 publication Critical patent/PL238119B1/en

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Abstract

Zgłoszenie dotyczy 1,2-diizoprenoilo-sn-glicero-3-fosfocholiny, o wzorze 1 oraz sposobu jej otrzymywania na drodze estryfikacji kwasu (E)-3,7,11-trimetylo-3-winylododeka-6,10-dienowego kompleksem sn-glicero-3-fosfocholiny i chlorku kadmu z udziałem czynnika sprzęgającego jakim jest N,N'-dicykloheksylokarbodiimid oraz w obecności 4-dimetyloaminopirydyny w środowisku bezwodnego chlorku metylenu. Zgłoszenie to może znaleźć zastosowanie w terapii chorób nowotworowych.The application relates to 1,2-diisoprenoyl-sn-glycerol-3-phosphocholine, of formula 1 and the method for its preparation by esterification of (E) -3,7,11-trimethyl-3-vinyl-dodeca-6,10-diene acid complex -glycero-3-phosphocholine and cadmium chloride with the participation of a coupling agent which is N, N'-dicyclohexylcarbodiimide and in the presence of 4-dimethylaminopyridine in anhydrous methylene chloride. This application may find application in the treatment of cancer.

PL418653(22)20160912A 2016-09-12 2016-09-12 1'2'-Di[3,7,11-trimethyl-3-vinyldodeca-6,10-dienyl]-sn-glycero-3'-phosphocholine and method for obtaining 1'2'-di[3,7,11-trimethyl-3-vinyldodeca-6,10-dienyl]-sn-glycero-3'-phosphocholine PL238119B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL418653(22)20160912A PL238119B1 (en) 2016-09-12 2016-09-12 1'2'-Di[3,7,11-trimethyl-3-vinyldodeca-6,10-dienyl]-sn-glycero-3'-phosphocholine and method for obtaining 1'2'-di[3,7,11-trimethyl-3-vinyldodeca-6,10-dienyl]-sn-glycero-3'-phosphocholine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL418653(22)20160912A PL238119B1 (en) 2016-09-12 2016-09-12 1'2'-Di[3,7,11-trimethyl-3-vinyldodeca-6,10-dienyl]-sn-glycero-3'-phosphocholine and method for obtaining 1'2'-di[3,7,11-trimethyl-3-vinyldodeca-6,10-dienyl]-sn-glycero-3'-phosphocholine

Publications (2)

Publication Number Publication Date
PL418653A1 true PL418653A1 (en) 2018-03-26
PL238119B1 PL238119B1 (en) 2021-07-05

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL418653(22)20160912A PL238119B1 (en) 2016-09-12 2016-09-12 1'2'-Di[3,7,11-trimethyl-3-vinyldodeca-6,10-dienyl]-sn-glycero-3'-phosphocholine and method for obtaining 1'2'-di[3,7,11-trimethyl-3-vinyldodeca-6,10-dienyl]-sn-glycero-3'-phosphocholine

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PL (1) PL238119B1 (en)

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Publication number Publication date
PL238119B1 (en) 2021-07-05

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