PL421031A1 - 7-ethoxy-naringenin-oxime and method for obtaining 7-ethoxy-naringenin-oxime - Google Patents
7-ethoxy-naringenin-oxime and method for obtaining 7-ethoxy-naringenin-oximeInfo
- Publication number
- PL421031A1 PL421031A1 PL421031A PL42103117A PL421031A1 PL 421031 A1 PL421031 A1 PL 421031A1 PL 421031 A PL421031 A PL 421031A PL 42103117 A PL42103117 A PL 42103117A PL 421031 A1 PL421031 A1 PL 421031A1
- Authority
- PL
- Poland
- Prior art keywords
- oxime
- naringenin
- ethoxy
- obtaining
- ethoxynaringenin
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- WTDHULULXKLSOZ-UHFFFAOYSA-N Hydroxylamine hydrochloride Chemical compound Cl.ON WTDHULULXKLSOZ-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 abstract 1
- 229940040526 anhydrous sodium acetate Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012043 crude product Substances 0.000 abstract 1
- 239000005457 ice water Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000002923 oximes Chemical class 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Przedmiotem zgłoszenia jest oksym 7-etoksynaringeniny o wzorze 2. Zgłoszenie obejmuje też sposób otrzymywania tego związku, który polega na tym, że do substratu, którym jest 7-etoksynaringenina o wzorze 1 dodaje się chlorowodorek hydroksyloaminy oraz bezwodny octan sodu w stosunku molowym co najmniej 1:1,5:1,5 oraz minimalną ilość alkoholu, co stanowi mieszaninę reakcyjną, którą zabezpiecza się przed dostępem światła i pozostawia w temperaturze od 45°C do 55°C na okres od 24 do 72 godzin przy ciągłym mieszaniu, po czym mieszaninę wylewa się do wody z lodem, wytrącony osad sączy się pod zmniejszonym ciśnieniem, a następnie otrzymany surowy produkt oczyszcza się.The subject of the application is 7-ethoxynaringenin oxime of formula 2. The application also includes a method for obtaining this compound, which consists in adding hydroxylamine hydrochloride and anhydrous sodium acetate in a molar ratio of at least 1 to the substrate which is 7-ethoxynaringenin of formula 1 : 1.5: 1.5 and a minimum amount of alcohol, which is the reaction mixture, which is protected from light and left at a temperature of 45 ° C to 55 ° C for 24 to 72 hours with constant stirring, after which the mixture poured into ice water, the precipitate is filtered under reduced pressure, and then the crude product obtained is purified.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL421031A PL236840B1 (en) | 2017-03-29 | 2017-03-29 | 7-ethoxy-naringenin-oxime and method for obtaining 7-ethoxy-naringenin-oxime |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL421031A PL236840B1 (en) | 2017-03-29 | 2017-03-29 | 7-ethoxy-naringenin-oxime and method for obtaining 7-ethoxy-naringenin-oxime |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL421031A1 true PL421031A1 (en) | 2018-10-08 |
| PL236840B1 PL236840B1 (en) | 2021-02-22 |
Family
ID=63688059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL421031A PL236840B1 (en) | 2017-03-29 | 2017-03-29 | 7-ethoxy-naringenin-oxime and method for obtaining 7-ethoxy-naringenin-oxime |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL236840B1 (en) |
-
2017
- 2017-03-29 PL PL421031A patent/PL236840B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL236840B1 (en) | 2021-02-22 |
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