PL420945A1 - Method for producing 3β,7α-dihydroxyandrost-5-en-17-one - Google Patents

Method for producing 3β,7α-dihydroxyandrost-5-en-17-one

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Publication number
PL420945A1
PL420945A1 PL420945A PL42094517A PL420945A1 PL 420945 A1 PL420945 A1 PL 420945A1 PL 420945 A PL420945 A PL 420945A PL 42094517 A PL42094517 A PL 42094517A PL 420945 A1 PL420945 A1 PL 420945A1
Authority
PL
Poland
Prior art keywords
dihydroxyandrost
producing
formula
kch
microorganism
Prior art date
Application number
PL420945A
Other languages
Polish (pl)
Other versions
PL235021B1 (en
Inventor
Ewa Kozłowska
Natalia Hoc
Monika Dymarska
Edyta Kostrzewa-Susłow
Jakub Grzeszczuk
Elżbieta Pląskowska
Monika Urbaniak
Łukasz Stępień
Tomasz Janeczko
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL420945A priority Critical patent/PL235021B1/en
Publication of PL420945A1 publication Critical patent/PL420945A1/en
Publication of PL235021B1 publication Critical patent/PL235021B1/en

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Zgłoszenie dotyczy sposobu wytwarzania 3ß,7?-dihydroksyandrost-5-en-17-onu o wzorze 2. Przedmiotowy wzór polega na tym, że w wyniku działania układu enzymatycznego zawartego w komórkach szczepu Isaria farinosa KCh KW1.1 o sekwencji 1, następuje hydroksylacja przy nieaktywowanym atomie węgla C-7. Uzyskany w ten sposób produkt wydziela się z wodnej kultury mikroorganizmu, znanym sposobem, przez ekstrakcję rozpuszczalnikiem organicznym niemieszającym się z wodą (chloroform).The application relates to a method for producing 3, 7'-dihydroxyandrost-5-en-17-one of formula 2. The subject formula is that as a result of the enzymatic system contained in cells of the strain Isaria farinosa KCh KW1.1 with sequence 1, hydroxylation occurs with the non-activated C-7 carbon atom. The product thus obtained is separated from the aqueous culture of the microorganism in a known manner by extraction with a water-immiscible organic solvent (chloroform).

PL420945A 2017-03-22 2017-03-22 Method for producing 3β,7α-dihydroxyandrost-5-en-17-one PL235021B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL420945A PL235021B1 (en) 2017-03-22 2017-03-22 Method for producing 3β,7α-dihydroxyandrost-5-en-17-one

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL420945A PL235021B1 (en) 2017-03-22 2017-03-22 Method for producing 3β,7α-dihydroxyandrost-5-en-17-one

Publications (2)

Publication Number Publication Date
PL420945A1 true PL420945A1 (en) 2018-09-24
PL235021B1 PL235021B1 (en) 2020-05-18

Family

ID=63578706

Family Applications (1)

Application Number Title Priority Date Filing Date
PL420945A PL235021B1 (en) 2017-03-22 2017-03-22 Method for producing 3β,7α-dihydroxyandrost-5-en-17-one

Country Status (1)

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PL (1) PL235021B1 (en)

Also Published As

Publication number Publication date
PL235021B1 (en) 2020-05-18

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