PL422978A1 - Pergolid do zastosowanie w leczeniu chorób oczu związanych z podwyższonym poziomem śródbłonkowego czynnika wzrostu naczyń (VEGF) oraz kompozycja farmaceutyczna zawierająca pergolid - Google Patents
Pergolid do zastosowanie w leczeniu chorób oczu związanych z podwyższonym poziomem śródbłonkowego czynnika wzrostu naczyń (VEGF) oraz kompozycja farmaceutyczna zawierająca pergolidInfo
- Publication number
- PL422978A1 PL422978A1 PL422978A PL42297817A PL422978A1 PL 422978 A1 PL422978 A1 PL 422978A1 PL 422978 A PL422978 A PL 422978A PL 42297817 A PL42297817 A PL 42297817A PL 422978 A1 PL422978 A1 PL 422978A1
- Authority
- PL
- Poland
- Prior art keywords
- vegf
- pergolide
- treatment
- growth factor
- eye diseases
- Prior art date
Links
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 title abstract 4
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 title abstract 4
- 208000030533 eye disease Diseases 0.000 title abstract 3
- YEHCICAEULNIGD-MZMPZRCHSA-N pergolide Chemical compound C1=CC([C@H]2C[C@@H](CSC)CN([C@@H]2C2)CCC)=C3C2=CNC3=C1 YEHCICAEULNIGD-MZMPZRCHSA-N 0.000 title abstract 3
- 229960004851 pergolide Drugs 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 title 2
- 230000003511 endothelial effect Effects 0.000 abstract 2
- 239000003102 growth factor Substances 0.000 abstract 2
- 230000006444 vascular growth Effects 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Przedmiotem zgłoszenia jest pergolid do zastosowania w leczeniu chorób oczu związanych z podwyższonym poziomem śródbłonkowego czynnika wzrostu naczyń (VEGF) oraz kompozycja farmaceutyczna do zastosowania w leczeniu chorób oczu związanych z podwyższonym poziomem śródbłonkowego czynnika wzrostu naczyń (VEGF), charakteryzująca się tym, że zawiera pergolid i dopuszczalny farmaceutycznie nośnik.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL422978A PL241086B1 (pl) | 2017-09-26 | 2017-09-26 | Pergolid do zastosowania w leczeniu zakrzepu naczyń siatkówki i/lub zatoru naczyń siatkówki oraz kompozycja farmaceutyczna zawierająca pergolid |
| US16/651,179 US20200289480A1 (en) | 2017-09-26 | 2018-09-25 | Pergolide for use in the treatment of eye diseases associated with an elevated level of vascular endothelial growth factor (vegf) and pharmaceutical composition containing pergolide |
| PCT/IB2018/057378 WO2019064164A1 (en) | 2017-09-26 | 2018-09-25 | PERGOLID FOR USE IN THE TREATMENT OF OCULAR DISEASES ASSOCIATED WITH A HIGH RATE OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) AND A PHARMACEUTICAL COMPOSITION CONTAINING PERGOLID |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL422978A PL241086B1 (pl) | 2017-09-26 | 2017-09-26 | Pergolid do zastosowania w leczeniu zakrzepu naczyń siatkówki i/lub zatoru naczyń siatkówki oraz kompozycja farmaceutyczna zawierająca pergolid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL422978A1 true PL422978A1 (pl) | 2019-04-08 |
| PL241086B1 PL241086B1 (pl) | 2022-08-01 |
Family
ID=65901310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL422978A PL241086B1 (pl) | 2017-09-26 | 2017-09-26 | Pergolid do zastosowania w leczeniu zakrzepu naczyń siatkówki i/lub zatoru naczyń siatkówki oraz kompozycja farmaceutyczna zawierająca pergolid |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20200289480A1 (pl) |
| PL (1) | PL241086B1 (pl) |
| WO (1) | WO2019064164A1 (pl) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160317474A1 (en) * | 2013-12-18 | 2016-11-03 | Emory University | Managing Visual Dysfunction or Loss of Vision for Diabetic Subjects |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL232974B1 (pl) * | 2015-12-09 | 2019-08-30 | Ofta Spolka Z Ograniczona Odpowiedzialnoscia | Zastosowanie agonistów receptorów dopaminergicznych typu 2 w leczeniu schorzeń oczu wywołanych przez podwyższony poziom śródbłonkopochodnego czynnika wzrostu naczyń |
-
2017
- 2017-09-26 PL PL422978A patent/PL241086B1/pl unknown
-
2018
- 2018-09-25 WO PCT/IB2018/057378 patent/WO2019064164A1/en not_active Ceased
- 2018-09-25 US US16/651,179 patent/US20200289480A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160317474A1 (en) * | 2013-12-18 | 2016-11-03 | Emory University | Managing Visual Dysfunction or Loss of Vision for Diabetic Subjects |
Non-Patent Citations (2)
| Title |
|---|
| CLAUDIO BUCOLO, PHARMACOLOGICAL MANAGEMENT OF OCULAR HYPERTENSION: CURRENT APPROACHES AND FUTURE PROSPECTIVE, 2013 * |
| MARC J. SIEGEL, EFFECT OF TOPICAL PERGOLIDE ON AQUEOUS DYNAMICS IN NORMAL AND GLAUCOMATOUS MONKEYS, 1987 * |
Also Published As
| Publication number | Publication date |
|---|---|
| PL241086B1 (pl) | 2022-08-01 |
| WO2019064164A1 (en) | 2019-04-04 |
| US20200289480A1 (en) | 2020-09-17 |
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