PL425802A1 - Method for producing dynamic substitute of a spongy bone - Google Patents
Method for producing dynamic substitute of a spongy boneInfo
- Publication number
- PL425802A1 PL425802A1 PL42580218A PL42580218A PL425802A1 PL 425802 A1 PL425802 A1 PL 425802A1 PL 42580218 A PL42580218 A PL 42580218A PL 42580218 A PL42580218 A PL 42580218A PL 425802 A1 PL425802 A1 PL 425802A1
- Authority
- PL
- Poland
- Prior art keywords
- solution
- substitute
- spongy bone
- producing dynamic
- temperature
- Prior art date
Links
- 210000000988 bone and bone Anatomy 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 229920000642 polymer Polymers 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004809 Teflon Substances 0.000 abstract 1
- 229920006362 Teflon® Polymers 0.000 abstract 1
- 229920000747 poly(lactic acid) Polymers 0.000 abstract 1
Landscapes
- Materials For Medical Uses (AREA)
Abstract
Przedmiotem zgłoszenia jest sposób wytwarzania dynamicznego substytutu kości gąbczastej, w którym sporządza się roztwór polilaktydu w dioksanie o stężeniu 1 - 12% wag., roztwór miesza się przez 3 - 24 h, w temperaturze 20 - 60°C, z szybkością 160 - 300 rpm, następnie dodaje się wodę demineralizowaną w ilości 8 - 20% wag. w stosunku do polimeru, po czym, po uzyskaniu klarownego roztworu polimeru, roztwór umieszcza się w formie teflonowej i zamraża się w temperaturze od -30 do -10°C, przez 12 - 36 h, a następnie zamrożony produkt umieszcza się w metanolu lub bezwodnym etanolu o temperaturze od -50 do -10°C na 3 - 5 dni, po czym uformowany substytut oczyszcza się w wodzie, a następnie suszy.The subject of the application is a method for the production of a dynamic substitute for cancellous bone, in which a solution of polylactide in dioxane with a concentration of 1 - 12% by weight is prepared, the solution is stirred for 3 - 24 h, at a temperature of 20 - 60 ° C, at a speed of 160 - 300 rpm. , then demineralized water is added in an amount of 8 - 20 wt.%. with respect to the polymer, then, after obtaining a clear polymer solution, the solution is placed in a Teflon form and frozen at -30 to -10 ° C for 12-36 h, and then the frozen product is placed in methanol or anhydrous ethanol at a temperature of -50 to -10 ° C for 3 - 5 days, then the formed substitute is purified in water and then dried.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL425802A PL236111B1 (en) | 2018-06-01 | 2018-06-01 | Method for producing dynamic substitute of a spongy bone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL425802A PL236111B1 (en) | 2018-06-01 | 2018-06-01 | Method for producing dynamic substitute of a spongy bone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL425802A1 true PL425802A1 (en) | 2019-12-02 |
| PL236111B1 PL236111B1 (en) | 2020-12-14 |
Family
ID=68655093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL425802A PL236111B1 (en) | 2018-06-01 | 2018-06-01 | Method for producing dynamic substitute of a spongy bone |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL236111B1 (en) |
-
2018
- 2018-06-01 PL PL425802A patent/PL236111B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL236111B1 (en) | 2020-12-14 |
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