PL428564A1 - Method of preparing 4-isothiocyanate-N-phenylferrocenecarboxamide - Google Patents
Method of preparing 4-isothiocyanate-N-phenylferrocenecarboxamideInfo
- Publication number
- PL428564A1 PL428564A1 PL428564A PL42856419A PL428564A1 PL 428564 A1 PL428564 A1 PL 428564A1 PL 428564 A PL428564 A PL 428564A PL 42856419 A PL42856419 A PL 42856419A PL 428564 A1 PL428564 A1 PL 428564A1
- Authority
- PL
- Poland
- Prior art keywords
- carbon atoms
- phenylferrocenecarboxamide
- equivalents
- amount
- aliphatic
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- -1 4-isothiocyano-N-phenylferrocenecarboxamide Chemical compound 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- UKJLNMAFNRKWGR-UHFFFAOYSA-N cyclohexatrienamine Chemical group NC1=CC=C=C[CH]1 UKJLNMAFNRKWGR-UHFFFAOYSA-N 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Natural products C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003463 sulfur Chemical class 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
- 150000003513 tertiary aromatic amines Chemical class 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Przedmiotem zgłoszenia jest sposób otrzymywania 4-izotiocyjano-N-fenyloferrocenokarboksyamidu o wzorze 1, który polega na tym, że N-(4-aminofenylo)ferrocenokarboksyamid poddaje się reakcji z siarkową pochodną metanu użytą w ilości 7 ekwiwalentów w stosunku do amidu w obecności trzeciorzędowej aminy alifatycznej zawierającej 3 - 6 atomów węgla w alkoholu metylowym lub alkoholu etylowym w temperaturze pokojowej, a następnie produkt pośredni poddaje się reakcji z alifatycznym diwęglanem zawierającym 4 - 10 atomów węgla użytym w ilości 1,1 ekwiwalenta w stosunku do kwasu w obecności trzeciorzędowej aminy aromatycznej zawierającej 7 atomów węgla a produkt reakcji wyodrębnia się na drodze ekstrakcji.The subject of the application is a method for the preparation of 4-isothiocyano-N-phenylferrocenecarboxamide of formula 1, which consists in reacting N- (4-aminophenyl) ferrocenecarboxamide with a sulfur derivative of methane used in the amount of 7 equivalents to the amide in the presence of a tertiary amine an aliphatic carbonate containing 3 - 6 carbon atoms in methyl alcohol or ethyl alcohol at room temperature, and then the intermediate is reacted with an aliphatic bicarbonate containing 4 - 10 carbon atoms in an amount of 1.1 equivalents to the acid in the presence of a tertiary aromatic amine containing 7 carbon atoms and the reaction product is isolated by extraction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL428564A PL238251B1 (en) | 2019-01-11 | 2019-01-11 | Method of preparing 4-isothiocyanate-N-phenylferrocenecarboxamide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL428564A PL238251B1 (en) | 2019-01-11 | 2019-01-11 | Method of preparing 4-isothiocyanate-N-phenylferrocenecarboxamide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL428564A1 true PL428564A1 (en) | 2020-07-13 |
| PL238251B1 PL238251B1 (en) | 2021-08-02 |
Family
ID=71512435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL428564A PL238251B1 (en) | 2019-01-11 | 2019-01-11 | Method of preparing 4-isothiocyanate-N-phenylferrocenecarboxamide |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL238251B1 (en) |
-
2019
- 2019-01-11 PL PL428564A patent/PL238251B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL238251B1 (en) | 2021-08-02 |
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