PL428746A1 - 5'-O-β-D- (4"-O-Methylglucopyranosyl)-2'-methoxyflavone and method of preparing 5'-O-β-D-(4"-O-methylglucopyranosyl) -2'-methoxyflavone - Google Patents

5'-O-β-D- (4"-O-Methylglucopyranosyl)-2'-methoxyflavone and method of preparing 5'-O-β-D-(4"-O-methylglucopyranosyl) -2'-methoxyflavone

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Publication number
PL428746A1
PL428746A1 PL428746A PL42874619A PL428746A1 PL 428746 A1 PL428746 A1 PL 428746A1 PL 428746 A PL428746 A PL 428746A PL 42874619 A PL42874619 A PL 42874619A PL 428746 A1 PL428746 A1 PL 428746A1
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PL
Poland
Prior art keywords
methylglucopyranosyl
methoxyflavone
preparing
water
methylglycosylation
Prior art date
Application number
PL428746A
Other languages
Polish (pl)
Other versions
PL240947B1 (en
Inventor
Mateusz Łużny
Ewa Kozłowska
Jarosław Popłoński
Marcelina Mazur
Tomasz Tronina
Edyta Kostrzewa-Susłow
Tomasz Janeczko
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
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Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL428746A priority Critical patent/PL240947B1/en
Publication of PL428746A1 publication Critical patent/PL428746A1/en
Publication of PL240947B1 publication Critical patent/PL240947B1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Wynalazek dotyczy 5'-O-ß-D-(4"-O-metyloglukopiranozylo)-2'-metoksyflawonu i sposób wytwarzania 5'-O-ß-D-(4"-O-metyloglukopiranozylo)-2'-metoksyflawonu o wzorze 2. W wyniku działania układu enzymatycznego zawartego w komórkach szczepu Beauveria bassiana KCh J1.5, następuje O-demetylacja i 4"-O-metyloglikozylacja. Uzyskany w ten sposób produkt wydziela się z wodnej kultury mikroorganizmu, znanym sposobem, przez ekstrakcję rozpuszczalnikiem organicznym niemieszającym się z wodą (octan etylu).The invention relates to 5'-O-ß-D- (4 "-O-methylglucopyranosyl) -2'-methoxyflavone and to a method of producing 5'-O-ß-D- (4" -O-methylglucopyranosyl) -2'-methoxyflavone with As a result of the action of the enzyme system contained in the cells of the Beauveria bassiana KCh J1.5 strain, O-demethylation and 4 "-O-methylglycosylation take place. The product obtained in this way is separated from the water culture of the microorganism by extraction with an organic solvent in a known manner. water-immiscible (ethyl acetate).

PL428746A 2019-01-31 2019-01-31 5'-O-β-D- (4"-O-Methylglucopyranosyl)-2'-methoxyflavone and method of preparing 5'-O-β-D-(4"-O-methylglucopyranosyl) -2'-methoxyflavone PL240947B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL428746A PL240947B1 (en) 2019-01-31 2019-01-31 5'-O-β-D- (4"-O-Methylglucopyranosyl)-2'-methoxyflavone and method of preparing 5'-O-β-D-(4"-O-methylglucopyranosyl) -2'-methoxyflavone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL428746A PL240947B1 (en) 2019-01-31 2019-01-31 5'-O-β-D- (4"-O-Methylglucopyranosyl)-2'-methoxyflavone and method of preparing 5'-O-β-D-(4"-O-methylglucopyranosyl) -2'-methoxyflavone

Publications (2)

Publication Number Publication Date
PL428746A1 true PL428746A1 (en) 2020-08-10
PL240947B1 PL240947B1 (en) 2022-07-04

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PL428746A PL240947B1 (en) 2019-01-31 2019-01-31 5'-O-β-D- (4"-O-Methylglucopyranosyl)-2'-methoxyflavone and method of preparing 5'-O-β-D-(4"-O-methylglucopyranosyl) -2'-methoxyflavone

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PL (1) PL240947B1 (en)

Also Published As

Publication number Publication date
PL240947B1 (en) 2022-07-04

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