PL427409A1 - Method of preparation of 4'-hydroxyflavone - Google Patents

Method of preparation of 4'-hydroxyflavone

Info

Publication number
PL427409A1
PL427409A1 PL427409A PL42740918A PL427409A1 PL 427409 A1 PL427409 A1 PL 427409A1 PL 427409 A PL427409 A PL 427409A PL 42740918 A PL42740918 A PL 42740918A PL 427409 A1 PL427409 A1 PL 427409A1
Authority
PL
Poland
Prior art keywords
hydroxyflavone
preparation
kch
microorganism
strain
Prior art date
Application number
PL427409A
Other languages
Polish (pl)
Other versions
PL235964B1 (en
Inventor
Mateusz Łużny
Ewa Kozłowska
Jarosław Popłoński
Monika Dymarska
Edyta Kostrzewa-Susłow
Tomasz Janeczko
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL427409A priority Critical patent/PL235964B1/en
Publication of PL427409A1 publication Critical patent/PL427409A1/en
Publication of PL235964B1 publication Critical patent/PL235964B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Zgłoszenie dotyczy sposobu wytwarzania 4'-hydroksyflawonu o wzorze 2. Postępując zgodnie z wynalazkiem, w wyniku działania układu enzymatycznego zawartego w komórkach szczepu Beauveria bassiana KCh J1, następuje O-demetylacja. Uzyskany w ten sposób produkt wydziela się z wodnej kultury mikroorganizmu, znanym sposobem, przez ekstrakcję rozpuszczalnikiem organicznym niemieszającym się z wodą (octan etylu).The application relates to a process for the production of 4'-hydroxy flavone of the formula 2. In accordance with the invention, O-demethylation occurs as a result of the enzyme system contained in the cells of the Beauveria bassiana KCh J1 strain. The product obtained in this way is separated from the aqueous culture of the microorganism by a known method by extraction with a water-immiscible organic solvent (ethyl acetate).

PL427409A 2018-10-15 2018-10-15 Method of preparation of 4'-hydroxyflavone PL235964B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL427409A PL235964B1 (en) 2018-10-15 2018-10-15 Method of preparation of 4'-hydroxyflavone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL427409A PL235964B1 (en) 2018-10-15 2018-10-15 Method of preparation of 4'-hydroxyflavone

Publications (2)

Publication Number Publication Date
PL427409A1 true PL427409A1 (en) 2020-04-20
PL235964B1 PL235964B1 (en) 2020-11-16

Family

ID=70281475

Family Applications (1)

Application Number Title Priority Date Filing Date
PL427409A PL235964B1 (en) 2018-10-15 2018-10-15 Method of preparation of 4'-hydroxyflavone

Country Status (1)

Country Link
PL (1) PL235964B1 (en)

Also Published As

Publication number Publication date
PL235964B1 (en) 2020-11-16

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