PL437236A1 - Biomateriał na bazie β-1,3-glukanu (kurdlanu) do regeneracji tkanki chrzęstnej i/lub kostnej oraz sposób jego wytwarzania - Google Patents
Biomateriał na bazie β-1,3-glukanu (kurdlanu) do regeneracji tkanki chrzęstnej i/lub kostnej oraz sposób jego wytwarzaniaInfo
- Publication number
- PL437236A1 PL437236A1 PL437236A PL43723621A PL437236A1 PL 437236 A1 PL437236 A1 PL 437236A1 PL 437236 A PL437236 A PL 437236A PL 43723621 A PL43723621 A PL 43723621A PL 437236 A1 PL437236 A1 PL 437236A1
- Authority
- PL
- Poland
- Prior art keywords
- curdlan
- glucan
- wpi
- production
- cartilage
- Prior art date
Links
- 229920002498 Beta-glucan Polymers 0.000 title abstract 5
- 229920002558 Curdlan Polymers 0.000 title abstract 5
- 239000001879 Curdlan Substances 0.000 title abstract 5
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 title abstract 5
- 229940078035 curdlan Drugs 0.000 title abstract 5
- 235000019316 curdlan Nutrition 0.000 title abstract 5
- 239000012620 biological material Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 210000000988 bone and bone Anatomy 0.000 title 1
- 210000000845 cartilage Anatomy 0.000 title 1
- 230000008929 regeneration Effects 0.000 title 1
- 238000011069 regeneration method Methods 0.000 title 1
- 108010046377 Whey Proteins Proteins 0.000 abstract 3
- 102000007544 Whey Proteins Human genes 0.000 abstract 3
- 235000021119 whey protein Nutrition 0.000 abstract 3
- 239000000243 solution Substances 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000012153 distilled water Substances 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 239000000017 hydrogel Substances 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Wynalazek dotyczy biomateriału na bazie naturalnego polisacharydu β-1,3-glukanu (kurdlanu) oraz izolatu białka serwatkowego (WPI), gdzie proporcje składników w odniesieniu do 100 ml wodnego roztworu wynoszą: 6 - 20% (w/v), korzystnie 8% (w/v)- β-1,3-glukan (kurdlan) oraz 20 - 50% (w/v), korzystnie 30% (w/v) — izolat białka serwatkowego (WPI). Wynalazek dotyczy też sposobu wytwarzania biomateriału na bazie β-1,3-glukanu (kurdlanu) znamienny tym, że najpierw przygotowuje się w wodzie destylowanej 20 - 50% (w/v) roztwór izolatu białka serwatkowego (WPI), korzystnie 30% (w/v) i dodaje się do β-1,3-glukanu (kurdlanu) w postaci proszku, tak aby stężenie kurdlanu względem roztworu WPI wynosiło 6 - 20% (w/v), korzystnie 8% (w/v), otrzymaną mieszaninę umieszcza się w formach i inkubuje przez 10 - 30 minut korzystnie 15 minut w temperaturze 90 - 120°C, korzystnie 90°C, następnie otrzymany hydrożel kurdlan-WPI poddaje się chłodzeniu w temperaturze pokojowej i sterylizuje.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL437236A PL240558B1 (pl) | 2021-03-08 | Biomateriał na bazie β-1,3-glukanu (kurdlanu) do regeneracji tkanki chrzęstnej i/lub kostnej oraz sposób jego wytwarzania |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL437236A PL240558B1 (pl) | 2021-03-08 | Biomateriał na bazie β-1,3-glukanu (kurdlanu) do regeneracji tkanki chrzęstnej i/lub kostnej oraz sposób jego wytwarzania |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL437236A1 true PL437236A1 (pl) | 2021-11-22 |
| PL240558B1 PL240558B1 (pl) | 2022-04-25 |
Family
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