PL437695A1 - Mixture of naphthoquinone and silver and use of the mixture as antimicrobial agent for the control of Pseudomonas aeruginosa - Google Patents
Mixture of naphthoquinone and silver and use of the mixture as antimicrobial agent for the control of Pseudomonas aeruginosaInfo
- Publication number
- PL437695A1 PL437695A1 PL437695A PL43769521A PL437695A1 PL 437695 A1 PL437695 A1 PL 437695A1 PL 437695 A PL437695 A PL 437695A PL 43769521 A PL43769521 A PL 43769521A PL 437695 A1 PL437695 A1 PL 437695A1
- Authority
- PL
- Poland
- Prior art keywords
- mixture
- silver
- naphthoquinone
- antimicrobial agent
- pseudomonas aeruginosa
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 241000589517 Pseudomonas aeruginosa Species 0.000 title abstract 2
- 239000004599 antimicrobial Substances 0.000 title abstract 2
- 229910052709 silver Inorganic materials 0.000 title abstract 2
- 239000004332 silver Substances 0.000 title abstract 2
- 229930192627 Naphthoquinone Natural products 0.000 title 1
- 150000002791 naphthoquinones Chemical class 0.000 title 1
- SVPKNMBRVBMTLB-UHFFFAOYSA-N 2,3-dichloronaphthalene-1,4-dione Chemical compound C1=CC=C2C(=O)C(Cl)=C(Cl)C(=O)C2=C1 SVPKNMBRVBMTLB-UHFFFAOYSA-N 0.000 abstract 3
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 244000052616 bacterial pathogen Species 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 239000002105 nanoparticle Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/38—Silver; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Wynalazek dotyczy bakteriobójczej mieszaniny nanocząstek srebra oraz 2,3-dichloro-1,4-naftochinonu, zwanego dichlonem wobec naturalnie opornej pałeczki ropy błękitnej, tj. Pseudomonas aeruginosa. Wynalazek dotyczy również medycznego zastosowania mieszaniny do zwalczania P. aeruginosa oraz zastosowania tej mieszaniny jako środka o działaniu przeciwbakteryjnym do stosowania zewnętrznie, tj. na skórę lub rany. Wykazany mechanizm oddziaływań nanocząstek srebra i dichlonu stanowi zjawisko o wysokim potencjale do zwalczania jednego z najgroźniejszych patogenów bakteryjnych człowieka - P. aeruginosa.The invention relates to a bactericidal mixture of silver nanoparticles and 2,3-dichloro-1,4-naphthoquinone, called a dichlon against a naturally resistant blue oil rod, i.e. Pseudomonas aeruginosa. The invention also relates to the medical use of the mixture for controlling P. aeruginosa and the use of the mixture as an antimicrobial agent for topical application, i.e. to the skin or wounds. The demonstrated mechanism of the interaction of silver and dichlon nanoparticles is a phenomenon with a high potential to combat one of the most dangerous human bacterial pathogens - P. aeruginosa.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL437695A PL242507B1 (en) | 2021-04-26 | 2021-04-26 | Mixture of naphthoquinone and silver and use of the mixture as antimicrobial agent for the control of Pseudomonas aeruginosa |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL437695A PL242507B1 (en) | 2021-04-26 | 2021-04-26 | Mixture of naphthoquinone and silver and use of the mixture as antimicrobial agent for the control of Pseudomonas aeruginosa |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL437695A1 true PL437695A1 (en) | 2022-04-11 |
| PL242507B1 PL242507B1 (en) | 2023-03-06 |
Family
ID=81076654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL437695A PL242507B1 (en) | 2021-04-26 | 2021-04-26 | Mixture of naphthoquinone and silver and use of the mixture as antimicrobial agent for the control of Pseudomonas aeruginosa |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL242507B1 (en) |
-
2021
- 2021-04-26 PL PL437695A patent/PL242507B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL242507B1 (en) | 2023-03-06 |
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