PL438253A1 - Mixture of naphthoquinone and silver and use of the mixture as an antibacterial agent for the control of Pseudomonas aeruginosa - Google Patents
Mixture of naphthoquinone and silver and use of the mixture as an antibacterial agent for the control of Pseudomonas aeruginosaInfo
- Publication number
- PL438253A1 PL438253A1 PL438253A PL43825321A PL438253A1 PL 438253 A1 PL438253 A1 PL 438253A1 PL 438253 A PL438253 A PL 438253A PL 43825321 A PL43825321 A PL 43825321A PL 438253 A1 PL438253 A1 PL 438253A1
- Authority
- PL
- Poland
- Prior art keywords
- mixture
- silver
- naphthoquinone
- antibacterial agent
- pseudomonas aeruginosa
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/38—Silver; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Wynalazek dotyczy sposobu aktywacji właściwości bakteriobójczych 2-hydroksy-3-(3-metylobut-2-enylo)-1,4-naftochinonu, tj. lapacholu, wobec naturalnie opornej pałeczki ropy błękitnej, tj. Pseudomonas aeruginosa, za pomocą srebra, zwłaszcza w formie nanocząstek srebra. Według wynalazku mieszanina zawiera działającą bakteriobójczo wobec P. aeruginosa dawkę srebra oraz 2-hydroksy-3-(3-metylobut-2-enylo)-1,4-naftochinonu zwanego lapacholem. Wynalazek dotyczy również medycznego zastosowania mieszaniny do zwalczania P. aeruginosa jako środka o działaniu przeciwbakteryjnym do stosowania zewnętrznie, tj. na skórę lub rany.The invention relates to a method of activating the bactericidal properties of 2-hydroxy-3- (3-methylbut-2-enyl) -1,4-naphthoquinone, i.e. lapachol, against a naturally resistant blue oil rod, i.e. Pseudomonas aeruginosa, with silver, especially in in the form of silver nanoparticles. According to the invention, the mixture contains a bactericidal dose of silver against P. aeruginosa and 2-hydroxy-3- (3-methylbut-2-enyl) -1,4-naphthoquinone called lapachol. The invention also relates to the medical use of the mixture for controlling P. aeruginosa as an antibacterial agent for topical application, i.e. to the skin or wounds.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL438253A PL438253A1 (en) | 2021-06-24 | 2021-06-24 | Mixture of naphthoquinone and silver and use of the mixture as an antibacterial agent for the control of Pseudomonas aeruginosa |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL438253A PL438253A1 (en) | 2021-06-24 | 2021-06-24 | Mixture of naphthoquinone and silver and use of the mixture as an antibacterial agent for the control of Pseudomonas aeruginosa |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL438253A1 true PL438253A1 (en) | 2022-06-27 |
Family
ID=82164083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL438253A PL438253A1 (en) | 2021-06-24 | 2021-06-24 | Mixture of naphthoquinone and silver and use of the mixture as an antibacterial agent for the control of Pseudomonas aeruginosa |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL438253A1 (en) |
-
2021
- 2021-06-24 PL PL438253A patent/PL438253A1/en unknown
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