PL442463A1 - Czopki doodbytnicze oraz ich zastosowanie - Google Patents

Czopki doodbytnicze oraz ich zastosowanie

Info

Publication number
PL442463A1
PL442463A1 PL442463A PL44246322A PL442463A1 PL 442463 A1 PL442463 A1 PL 442463A1 PL 442463 A PL442463 A PL 442463A PL 44246322 A PL44246322 A PL 44246322A PL 442463 A1 PL442463 A1 PL 442463A1
Authority
PL
Poland
Prior art keywords
weight
rectal suppositories
acylglycerols
carboxymethylcellulose
application
Prior art date
Application number
PL442463A
Other languages
English (en)
Other versions
PL247439B1 (pl
Inventor
Adam Kiciak
Magdalena JANDER
Original Assignee
Probiome Spółka Z Ograniczoną Odpowiedzialnością
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Probiome Spółka Z Ograniczoną Odpowiedzialnością filed Critical Probiome Spółka Z Ograniczoną Odpowiedzialnością
Priority to PL442463A priority Critical patent/PL247439B1/pl
Priority to PCT/PL2023/050083 priority patent/WO2024076249A1/en
Priority to EP23875291.9A priority patent/EP4598509A1/en
Publication of PL442463A1 publication Critical patent/PL442463A1/pl
Publication of PL247439B1 publication Critical patent/PL247439B1/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/717Celluloses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734Alginic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

Przedmiotem zgłoszenia jest czopek doodbytniczy zawierający maślan sodu, acyloglicerole, alginian sodu oraz karboksymetylocelulozę, charakteryzujący się tym, że zawiera od 40% do 50% wagowych acylogliceroli, od 15% do 35% wagowych maślanu sodu i od 25% do 38% wagowych alginianu sodu i karboksymetylocelulozy. Zgłoszenie dotyczy też zastosowania czopka do nawilżania ścian jelita grubego.
PL442463A 2022-10-07 2022-10-07 Czopki doodbytnicze oraz ich zastosowanie PL247439B1 (pl)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PL442463A PL247439B1 (pl) 2022-10-07 2022-10-07 Czopki doodbytnicze oraz ich zastosowanie
PCT/PL2023/050083 WO2024076249A1 (en) 2022-10-07 2023-10-09 Rectal suppositories and their use
EP23875291.9A EP4598509A1 (en) 2022-10-07 2023-10-09 Rectal suppositories and their use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL442463A PL247439B1 (pl) 2022-10-07 2022-10-07 Czopki doodbytnicze oraz ich zastosowanie

Publications (2)

Publication Number Publication Date
PL442463A1 true PL442463A1 (pl) 2024-04-08
PL247439B1 PL247439B1 (pl) 2025-06-30

Family

ID=90608441

Family Applications (1)

Application Number Title Priority Date Filing Date
PL442463A PL247439B1 (pl) 2022-10-07 2022-10-07 Czopki doodbytnicze oraz ich zastosowanie

Country Status (3)

Country Link
EP (1) EP4598509A1 (pl)
PL (1) PL247439B1 (pl)
WO (1) WO2024076249A1 (pl)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101292969A (zh) * 2007-04-27 2008-10-29 青岛东海药业有限公司 丁酸(酪酸)在制备治疗肛肠疾病药物中的应用
PL216229B1 (pl) * 2007-01-25 2014-03-31 Biolek Społka Z Ograniczoną Odpowiedzialnością Preparat zawierający maślan sodu i zastosowanie preparatu zawierającego maślan sodu

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL216229B1 (pl) * 2007-01-25 2014-03-31 Biolek Społka Z Ograniczoną Odpowiedzialnością Preparat zawierający maślan sodu i zastosowanie preparatu zawierającego maślan sodu
CN101292969A (zh) * 2007-04-27 2008-10-29 青岛东海药业有限公司 丁酸(酪酸)在制备治疗肛肠疾病药物中的应用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
POLPHARMA: "17.12.2021; https://polpharma.pl/wp-content/uploads/2020/08/212013_.pdf", DEBUTIR CZOPKI OPIS WYROBU MEDYCZNEGO *
WISCHMEYER P, PEMBERTON JH, PHILLIPS SF: "Mayo Clin Proc. 1993 Oct;68(10):978-81. doi: 10.1016/s0025-6196(12)62270-8", CHRONIC POUCHITIS AFTER ILEAL POUCH-ANAL ANASTOMOSIS: RESPONSES TO BUTYRATE AND GLUTAMINE SUPPOSITORIES IN A PILOT STUDY *

Also Published As

Publication number Publication date
WO2024076249A1 (en) 2024-04-11
EP4598509A1 (en) 2025-08-13
PL247439B1 (pl) 2025-06-30

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