PL443843A1 - Sposób wytwarzania wielordzeniowego nanonośnika polielektrolitowego syntetyzowanego na bazie siarczanu dodecylu sodu i wielordzeniowy nanonośnik polielektrolitowy do zastosowania do leczenia w terapii przeciwnowotworowej - Google Patents

Sposób wytwarzania wielordzeniowego nanonośnika polielektrolitowego syntetyzowanego na bazie siarczanu dodecylu sodu i wielordzeniowy nanonośnik polielektrolitowy do zastosowania do leczenia w terapii przeciwnowotworowej

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Publication number
PL443843A1
PL443843A1 PL443843A PL44384323A PL443843A1 PL 443843 A1 PL443843 A1 PL 443843A1 PL 443843 A PL443843 A PL 443843A PL 44384323 A PL44384323 A PL 44384323A PL 443843 A1 PL443843 A1 PL 443843A1
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PL
Poland
Prior art keywords
polyelectrolyte
nanocarrier
multicore
producing
synthesized
Prior art date
Application number
PL443843A
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English (en)
Other versions
PL247686B1 (pl
Inventor
Marzena Szwed
Agnieszka MARCZAK
Krzysztof Szczepanowicz
Original Assignee
Uniwersytet Łódzki
Instytut Katalizy I Fizykochemii Powierzchni Im. Jerzego Habera Polskiej Akademii Nauk
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Application filed by Uniwersytet Łódzki, Instytut Katalizy I Fizykochemii Powierzchni Im. Jerzego Habera Polskiej Akademii Nauk filed Critical Uniwersytet Łódzki
Priority to PL443843A priority Critical patent/PL247686B1/pl
Publication of PL443843A1 publication Critical patent/PL443843A1/pl
Publication of PL247686B1 publication Critical patent/PL247686B1/pl

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Przedmiotem zgłoszenia jest sposób wytwarzania wielordzeniowego nanonośnika polielektrolitowego syntetyzowanego na bazie siarczanu dodecylu sodu i wielordzeniowy nanonośnik polielektrolitowy do zastosowania do leczenia w terapii przeciwnowotworowej. Sposób wytworzenia wielordzeniowego nanonośnika polielektrolitowego, obejmuje następujące etapy. Solubilizacja wybranego lipofilowego czynnika aktywnego w micelach SDS, wytworzenie kompleksu micel SDS z przeciwnie naładowanym polielektrolitem — polikationem, opłaszczenie powstałego dodatnio naładowanego nanonośnika (kompleksu SDS/polikation) polianionem.
PL443843A 2023-02-21 2023-02-21 Sposób wytwarzania wielordzeniowego nanonośnika polielektrolitowego syntetyzowanego na bazie siarczanu dodecylu sodu i wielordzeniowy nanonośnik polielektrolitowy do zastosowania do leczenia w terapii przeciwnowotworowej PL247686B1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL443843A PL247686B1 (pl) 2023-02-21 2023-02-21 Sposób wytwarzania wielordzeniowego nanonośnika polielektrolitowego syntetyzowanego na bazie siarczanu dodecylu sodu i wielordzeniowy nanonośnik polielektrolitowy do zastosowania do leczenia w terapii przeciwnowotworowej

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL443843A PL247686B1 (pl) 2023-02-21 2023-02-21 Sposób wytwarzania wielordzeniowego nanonośnika polielektrolitowego syntetyzowanego na bazie siarczanu dodecylu sodu i wielordzeniowy nanonośnik polielektrolitowy do zastosowania do leczenia w terapii przeciwnowotworowej

Publications (2)

Publication Number Publication Date
PL443843A1 true PL443843A1 (pl) 2024-08-26
PL247686B1 PL247686B1 (pl) 2025-08-18

Family

ID=92503389

Family Applications (1)

Application Number Title Priority Date Filing Date
PL443843A PL247686B1 (pl) 2023-02-21 2023-02-21 Sposób wytwarzania wielordzeniowego nanonośnika polielektrolitowego syntetyzowanego na bazie siarczanu dodecylu sodu i wielordzeniowy nanonośnik polielektrolitowy do zastosowania do leczenia w terapii przeciwnowotworowej

Country Status (1)

Country Link
PL (1) PL247686B1 (pl)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040241202A1 (en) * 2001-04-19 2004-12-02 Johanna Chluba Biomaterials with bioactive coatings
WO2006029845A2 (en) * 2004-09-14 2006-03-23 Nanodel Technologies Gmbh Delivery vehicle containing nanoparticles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040241202A1 (en) * 2001-04-19 2004-12-02 Johanna Chluba Biomaterials with bioactive coatings
WO2006029845A2 (en) * 2004-09-14 2006-03-23 Nanodel Technologies Gmbh Delivery vehicle containing nanoparticles

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LE BROC-RYCKEWAERT D ET AL: "Int J Pharm. 2013 Oct 1;454(2):712-9. doi: 10.1016/j.ijpharm.2013.05.018.", DEVELOPMENT OF INNOVATIVE PACLITAXEL-LOADED SMALL PLGA NANOPARTICLES: STUDY OF THEIR ANTIPROLIFERATIVE ACTIVITY AND THEIR MOLECULAR INTERACTIONS ON PROSTATIC CANCER CELLS, DOI: skrót *
PAN A ET AL: "Nanotechnology. 2016 Oct 21;27(42):425103. doi: 10.1088/0957-4484/27/42/425103", DISULFIDE-CROSSLINKED NANOMICELLES CONFER CANCER-SPECIFIC DRUG DELIVERY AND IMPROVE EFFICACY OF PACLITAXEL IN BLADDER CANCER *

Also Published As

Publication number Publication date
PL247686B1 (pl) 2025-08-18

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