PL445154A1 - 4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol and method for producing 4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol - Google Patents

4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol and method for producing 4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol

Info

Publication number
PL445154A1
PL445154A1 PL445154A PL44515423A PL445154A1 PL 445154 A1 PL445154 A1 PL 445154A1 PL 445154 A PL445154 A PL 445154A PL 44515423 A PL44515423 A PL 44515423A PL 445154 A1 PL445154 A1 PL 445154A1
Authority
PL
Poland
Prior art keywords
hydroxyxanthohumol
methylglucopyranosyl
producing
hours
formula
Prior art date
Application number
PL445154A
Other languages
Polish (pl)
Inventor
Tomasz Tronina
Daniel Radosław Łój
Agnieszka Bartmańska
Jarosław Popłoński
Ewa Huszcza
Tomasz Janeczko
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL445154A priority Critical patent/PL445154A1/en
Publication of PL445154A1 publication Critical patent/PL445154A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)

Abstract

Przedmiotem zgłoszenia jest związek 4'-O-β-D-(4"'-O-metyloglukopiranozylo)-4"-hydroksyksantohumol o wzorze 2. Zgłoszenie obejmuje, ponadto sposób wytwarzania 4'-O-β-D-(4"'-O-metyloglukopiranozylo)-4"-hydroksyksantohumolu charakteryzujący się tym, że do podłoża odpowiedniego dla grzybów strzępkowych wprowadza się szczep Beauveria bassiana BBT, następnie po upływie co najmniej 72 godzin do hodowli wprowadza się substrat, którym jest ksantohumol o wzorze 1, rozpuszczony w rozpuszczalniku organicznym mieszającym się z wodą, transformację prowadzi się w temperaturze od 20 do 30 stopni Celsjusza, przy ciągłym wstrząsaniu, co najmniej 24 godziny, po czym produkt ekstrahuje się rozpuszczalnikiem organicznym niemieszającym się z wodą i oczyszcza chromatograficznie.The subject of the application is the compound 4'-O-β-D-(4"'-O-methylglucopyranosyl)-4"-hydroxyxanthohumol of formula 2. The application further covers a method for producing 4'-O-β-D-(4"'-O-methylglucopyranosyl)-4"-hydroxyxanthohumol characterized in that the Beauveria bassiana BBT strain is introduced into a medium suitable for filamentous fungi, then after at least 72 hours a substrate is introduced into the culture, which is xanthohumol of formula 1 dissolved in an organic solvent miscible with water, the transformation is carried out at a temperature of 20 to 30 degrees Celsius, with continuous shaking, for at least 24 hours, after which the product is extracted with an organic solvent immiscible with water and purified chromatographically.

PL445154A 2023-06-07 2023-06-07 4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol and method for producing 4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol PL445154A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL445154A PL445154A1 (en) 2023-06-07 2023-06-07 4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol and method for producing 4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL445154A PL445154A1 (en) 2023-06-07 2023-06-07 4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol and method for producing 4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol

Publications (1)

Publication Number Publication Date
PL445154A1 true PL445154A1 (en) 2024-12-09

Family

ID=93799842

Family Applications (1)

Application Number Title Priority Date Filing Date
PL445154A PL445154A1 (en) 2023-06-07 2023-06-07 4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol and method for producing 4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol

Country Status (1)

Country Link
PL (1) PL445154A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL210084B1 (en) * 2008-06-16 2011-12-30 Univ Przyrodniczy We Wrocławiu The manner of production of 4'-O- -D-glucosylo-2'-4-dihydroxy-6'-metoxy-3'-prenylochalcone

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL210084B1 (en) * 2008-06-16 2011-12-30 Univ Przyrodniczy We Wrocławiu The manner of production of 4'-O- -D-glucosylo-2'-4-dihydroxy-6'-metoxy-3'-prenylochalcone

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HUSZCZA E, BARTMAŃSKA A, TRONINA T., GLYCOSYLATION OF XANTHOHUMOL BY FUNGI. Z NATURFORSCH C J BIOSCI. 2008 JUL-AUG;63(7-8):557-60. DOI:10.1515/ZNC-2008-7-815. *
TOMASZ TRONINA, AGNIESZKA BARTMAŃSKA, MAGDALENA MILCZAREK, JOANNA WIETRZYK, JAROSŁAW POPŁOŃSKI, EDWARD RÓJ, EWA HUSZCZA, ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITY OF GLYCOSIDES OBTAINED BY BIOTRANSFORMATION OF XANTHOHUMOL, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, VOLUME 23, ISSUE 7, 2013, PAGES 1957-1960, HTTPS://DOI.ORG/10.1016/J.BMCL.2013.02.031. *

Similar Documents

Publication Publication Date Title
PL432970A1 (en) 2-Hydroxy-5'-methyl-3-O-β-D-(4''-O-methylglucopyranosyl)-chalcone and method of producing 2-hydroxy-5'-methyl-3-O-β-D-(4"-O-methylglucopyranosyl)-chalcone
PL445158A1 (en) Method of producing 4'-O-β-D-(4'''-O-methylglucopyranosyl)xanthohumol
PL435323A1 (en) 6-Hydroxymethyl-3'-O-β-D-(4'-O-methylglucopyranosyl)-flavanone and method of preparation of 6-hydroxymethyl-3'-O-β-D-(4'-O-methylglucopyranosyl)-flavanone
PL438639A1 (en) 2'-Methyl-3'-O-β-D-(4''-O-methylglucopyranosyl)-flavone and method for producing 2'-methyl-3'-O-β-D-(4''-O-methylglucopyranosyl) )-flavone
PL445157A1 (en) Method of producing 4'-O-β-D-(4'''-O-methylglucopyranosyl)xanthohumol
PL435321A1 (en) 4'-Hydroxy-6-methylene-O-β-D-(4'-O-methylglucopyranosyl)-flavanone and method of preparation of 4'-hydroxy-6-methylene-O-β-D-(4'-O-methylglucopyranosyl)-flavanone
PL445160A1 (en) Method of producing 4'-O-β-D-(4'''-O-methylglucopyranosyl)-xanthohumol
PL445156A1 (en) Method of producing 4'-O-β-D-(4'''-O-methylglucopyranosyl)-xanthohumol
PL443910A1 (en) 2'-Hydroxy-5'-chloro-3-O-β-D-(4''-O-methylglucopyranosyl)-chalcone and method for preparing 2'-hydroxy-5'-chloro-3-O-β-D-(4''-O-methylglucopyranosyl)-chalcone
PL445155A1 (en) Method of producing 4'-O-β-D-(4'''-O-methylglucopyranosyl)-4"-hydroxyxanthohumol
PL447068A1 (en) 6-Bromo-8-nitro-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavone and method for producing 6-Bromo-8-nitro-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavone
PL443857A1 (en) 3-Chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for producing 3-chloro-2'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone
PL443538A1 (en) 8-Bromo-6-chloro-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavan-4-ol and method for producing 8-bromo-6-chloro-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavan-4-ol
PL445159A1 (en) Method of producing 4'-O-β-D-(4'''-O-methylglucopyranosyl)-xanthohumol
PL443911A1 (en) 3-Chloro-2'-hydroxy-5'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for preparing 3-chloro-2'-hydroxy-5'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone
PL443913A1 (en) 2-Chloro-2',5-dihydroxy-3'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for producing 2-chloro-2',5-dihydroxy-3'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone
PL443912A1 (en) 4-Chloro-2'-hydroxy-3-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for preparing 4-chloro-2'-hydroxy-3-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone
PL448609A1 (en) Method for producing 3'-chloro-4'-O-β-D-(4''-O-methylglucopyranosyl)-flavone
PL447065A1 (en) 8-Amino-6-chloro-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavone and method of producing 8-amino-6-chloro-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavone
PL443915A1 (en) 4-Chloro-2'-hydroxy-5'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for preparing of 4-chloro-2'-hydroxy-5'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone
PL443914A1 (en) Method for preparing 3-chloro-2'-hydroxy-5'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone
PL443909A1 (en) 2-Chloro-2'-hydroxy-5'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone and method for preparing 2-chloro-2'-hydroxy-5'-O-β-D-(4''-O-methylglucopyranosyl)-dihydrochalcone
PL443870A1 (en) 6-Methyl-8-nitro-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavone and method for producing 6-methyl-8-nitro-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavone
PL439736A1 (en) 5-O-β-D-(4''-O-methylglucopyranosyl)-flavanone and method for producing 5-O-β-D-(4''-O-methylglucopyranosyl)-flavanone
PL443539A1 (en) 8-Bromo-6-chloro-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavone and method for preparing 8-bromo-6-chloro-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavone