PT100344A - Factores polipeptidicos mitogenicos gliais, e seu processo de preparacao, ensaio da actividade mitogenica, sequencias de adn que codificam os factores e construcoes de adn que as compreendem, celulas hospedeiras, formulacoes farmaceutica ou veterinaria, uso dos polipeptidos, anticorpo, e sequencia genetica codificando actividade mitogenica de celulas gliais. - Google Patents

Factores polipeptidicos mitogenicos gliais, e seu processo de preparacao, ensaio da actividade mitogenica, sequencias de adn que codificam os factores e construcoes de adn que as compreendem, celulas hospedeiras, formulacoes farmaceutica ou veterinaria, uso dos polipeptidos, anticorpo, e sequencia genetica codificando actividade mitogenica de celulas gliais.

Info

Publication number
PT100344A
PT100344A PT100344A PT10034492A PT100344A PT 100344 A PT100344 A PT 100344A PT 100344 A PT100344 A PT 100344A PT 10034492 A PT10034492 A PT 10034492A PT 100344 A PT100344 A PT 100344A
Authority
PT
Portugal
Prior art keywords
factors
glitary
mitogenic
dna
mitogenics
Prior art date
Application number
PT100344A
Other languages
English (en)
Other versions
PT100344B (pt
Inventor
Andrew David John Goodearl
Michael Derek Waterfield
Paul Stroobant
Luisa Minghetti
Mark Andrew Marchionni
Original Assignee
Ludwig Inst Cancer Res
Cambridge Neuroscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Inst Cancer Res, Cambridge Neuroscience Inc filed Critical Ludwig Inst Cancer Res
Publication of PT100344A publication Critical patent/PT100344A/pt
Publication of PT100344B publication Critical patent/PT100344B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT100344A 1991-04-10 1992-04-03 Factores polipeptidicos mitogenicos gliais, e seu processo de preparacao, ensaio da actividade mitogenica, sequencias de adn que codificam os factores e construcoes de adn que as compreendem, celulas hospedeiras, formulacoes farmaceutica ou veterinaria, uso dos polipeptidos, anticorpo, e sequencia genetica codificando actividade mitogenica de celulas gliais. PT100344B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919107566A GB9107566D0 (en) 1991-04-10 1991-04-10 Glial mitogenic factors,their preparation and use

Publications (2)

Publication Number Publication Date
PT100344A true PT100344A (pt) 1993-07-30
PT100344B PT100344B (pt) 1999-08-31

Family

ID=10692987

Family Applications (1)

Application Number Title Priority Date Filing Date
PT100344A PT100344B (pt) 1991-04-10 1992-04-03 Factores polipeptidicos mitogenicos gliais, e seu processo de preparacao, ensaio da actividade mitogenica, sequencias de adn que codificam os factores e construcoes de adn que as compreendem, celulas hospedeiras, formulacoes farmaceutica ou veterinaria, uso dos polipeptidos, anticorpo, e sequencia genetica codificando actividade mitogenica de celulas gliais.

Country Status (13)

Country Link
EP (1) EP0579640B1 (pt)
JP (1) JPH06507544A (pt)
KR (1) KR100274305B1 (pt)
AT (1) ATE221083T1 (pt)
AU (2) AU1450992A (pt)
CA (1) CA2108119C (pt)
DE (1) DE69232693T2 (pt)
DK (1) DK0579640T3 (pt)
GB (1) GB9107566D0 (pt)
IE (1) IE921062A1 (pt)
PT (1) PT100344B (pt)
WO (1) WO1992018627A1 (pt)
ZA (1) ZA922441B (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530109A (en) * 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
IL101943A0 (en) * 1991-05-24 1992-12-30 Genentech Inc Structure,production and use of heregulin
US5367060A (en) * 1991-05-24 1994-11-22 Genentech, Inc. Structure, production and use of heregulin
US5834229A (en) * 1991-05-24 1998-11-10 Genentech, Inc. Nucleic acids vectors and host cells encoding and expressing heregulin 2-α
EP0656069A4 (en) * 1992-08-10 1996-07-10 Cambridge Neuroscience Inc CELL PROLIFERATION INHIBITORS, THEIR PRODUCTION AND USE.
GB9217316D0 (en) * 1992-08-14 1992-09-30 Ludwig Inst Cancer Res Schwann cell mitogenic factor,its preparation and use
US5770567A (en) * 1994-11-14 1998-06-23 Genentech, Inc. Sensory and motor neuron derived factor (SMDF)
US6033660A (en) * 1995-05-10 2000-03-07 Genentech, Inc. Method of treating a nervous system injury with cultured schwann cells
US5849585A (en) * 1995-05-10 1998-12-15 Genetech, Inc. Isolating and culturing Schwann cells
US5721139A (en) * 1995-05-10 1998-02-24 Genentech, Inc. Isolating and culturing schwann cells
US5912326A (en) * 1995-09-08 1999-06-15 President And Fellows Of Harvard College Cerebellum-derived growth factors
DE69732711T2 (de) 1996-07-12 2006-03-16 Genentech, Inc., South San Francisco Gamma-heregulin
US6136558A (en) * 1997-02-10 2000-10-24 Genentech, Inc. Heregulin variants
US6387638B1 (en) 1997-02-10 2002-05-14 Genentech, Inc. Heregulin variants
WO1999031505A1 (en) * 1997-12-15 1999-06-24 Shire Laboratories Inc. Neurotrophic factor assay
US20010023241A1 (en) 1998-02-04 2001-09-20 Sliwkowski Mark X. Use of heregulin as a growth factor
AUPP785098A0 (en) 1998-12-21 1999-01-21 Victor Chang Cardiac Research Institute, The Treatment of heart disease
US6635249B1 (en) 1999-04-23 2003-10-21 Cenes Pharmaceuticals, Inc. Methods for treating congestive heart failure
ITMI20011057A1 (it) 2001-05-22 2002-11-22 Bracco Imaging Spa Preparazione ed uso di peptidi ciclici e ramificati e loro deriati marcati come agenti terapeutici agonisti o antagonisti della colecistochi
AU2002304965A1 (en) 2002-05-24 2003-12-12 Zensun (Shanghai) Sci-Tech.Ltd Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
US7241392B2 (en) 2004-09-09 2007-07-10 Dresser-Rand Company Rotary separator and method
US20070213264A1 (en) 2005-12-02 2007-09-13 Mingdong Zhou Neuregulin variants and methods of screening and using thereof
ES2530526T3 (es) 2005-12-30 2015-03-03 Zensun Shanghai Science And Technology Ltd Liberación extendida de neurregulina para mejorar la función cardíaca
EP3777878A1 (en) 2008-08-15 2021-02-17 Acorda Therapeutics, Inc. Compositions and methods for treatment during non-acute periods following cns neurological injury
WO2013053076A1 (en) 2011-10-10 2013-04-18 Zensun （Shanghai）Science & Technology Limited Compositions and methods for treating heart failure
EP3895724B1 (en) 2013-05-22 2025-06-25 Zensun (Shanghai) Science and Technology, Co., Ltd. Extended release of neuregulin for treating heart failure

Also Published As

Publication number Publication date
EP0579640B1 (en) 2002-07-24
DK0579640T3 (da) 2002-11-11
IE921062A1 (en) 1992-10-21
GB9107566D0 (en) 1991-05-29
DE69232693T2 (de) 2003-04-03
PT100344B (pt) 1999-08-31
JPH06507544A (ja) 1994-09-01
ATE221083T1 (de) 2002-08-15
CA2108119A1 (en) 1992-10-11
AU6808396A (en) 1997-01-16
WO1992018627A1 (en) 1992-10-29
AU703772B2 (en) 1999-04-01
EP0579640A1 (en) 1994-01-26
AU1450992A (en) 1992-11-17
CA2108119C (en) 2009-06-30
KR100274305B1 (ko) 2000-12-15
DE69232693D1 (de) 2002-08-29
ZA922441B (en) 1992-11-25

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Effective date: 19930205

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Effective date: 19990503

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