PT100357A - Compostos lactama macrociclicos, seu processo de preparacao e intermediarios, e composicoes que os contem - Google Patents

Compostos lactama macrociclicos, seu processo de preparacao e intermediarios, e composicoes que os contem

Info

Publication number: PT100357A
Authority: PT; Portugal
Prior art keywords: compounds; compositions; lactama; intermediaries; macrocyclic
Prior art date: 1991-04-09

Application number

PT100357A

Other languages

English (en)

Other versions

PT100357B (pt

Inventor

Richard J Pariza

Leslie A Freiberg

Carla Edwards

Hugh N Nellans

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-09

Filing date

1992-04-08

Publication date

1993-07-30

1992-04-08 Application filed by Abbott Lab filed Critical Abbott Lab

1993-07-30 Publication of PT100357A publication Critical patent/PT100357A/pt

1999-06-30 Publication of PT100357B publication Critical patent/PT100357B/pt

Links

150000001875 compounds Chemical class 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
238000000034 method Methods 0.000 abstract 2
210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
-1 lactam compounds Chemical class 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Polyamides (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Cephalosporin Compounds (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PT100357A 1991-04-09 1992-04-08 Compostos lactama macrociclicos, seu processo de preparacao e intermediarios, e composicoes que os contem PT100357B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US68283691A	1991-04-09	1991-04-09

Publications (2)

Publication Number	Publication Date
PT100357A true PT100357A (pt)	1993-07-30
PT100357B PT100357B (pt)	1999-06-30

Family

ID=24741372

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT100357A PT100357B (pt)	1991-04-09	1992-04-08	Compostos lactama macrociclicos, seu processo de preparacao e intermediarios, e composicoes que os contem

Country Status (15)

Country	Link
US (1)	US5538961A (pt)
EP (1)	EP0579770B1 (pt)
JP (1)	JPH06509326A (pt)
KR (1)	KR100222014B1 (pt)
AT (1)	ATE139697T1 (pt)
AU (1)	AU663089B2 (pt)
CA (1)	CA2103913A1 (pt)
DE (1)	DE69211845T2 (pt)
DK (1)	DK0579770T3 (pt)
ES (1)	ES2091471T3 (pt)
GR (1)	GR3020853T3 (pt)
IE (1)	IE73236B1 (pt)
IL (1)	IL101504A (pt)
PT (1)	PT100357B (pt)
WO (1)	WO1992018134A1 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1122261A3 (en) *	2000-01-31	2001-09-26	Pfizer Products Inc.	13 and 14-membered antibacterial macrolides
CA2399198A1 (en)	2000-02-18	2001-08-23	Christopher Carreras	Motilide compounds
WO2002014338A1 (fr) *	2000-08-17	2002-02-21	The Kitasato Institute	Nouveaux derives de pseudoerythromycine
CA2429709A1 (en) *	2000-12-01	2002-07-04	Gary Ashley	Motilide compounds
US20020094962A1 (en) *	2000-12-01	2002-07-18	Gary Ashley	Motilide compounds
SI1532131T1 (sl) *	2002-08-29	2009-04-30	Pfizer	Motilidne spojine
AU2003273318A1 (en) *	2002-09-12	2004-04-30	University Of Chicago	Monitoring and diagnosis of gastric emptying and gastroparesis
DE602004025569D1 (de)	2003-06-18	2010-04-01	Tranzyme Pharma Inc	Makrozyklische motilin rezeptorantagonisten
US7407941B2 (en) *	2003-08-26	2008-08-05	Pfizer, Inc.	N-desmethyl-N-substituted-11-deoxyerythromycin compounds
US20050113319A1 (en) *	2003-08-26	2005-05-26	Christopher Carreras	11-Deoxy-6,9-ether erythromycin compounds
US7211568B2 (en) *	2003-12-18	2007-05-01	Kosan Biosciences Incorporated	9-Desoxoerythromycin compounds as prokinetic agents
US7582611B2 (en)	2005-05-24	2009-09-01	Pfizer Inc.	Motilide compounds
BRPI0619556A2 (pt) *	2005-12-08	2011-10-04	Pfizer	processo para desmetilação de grupo 3' -dimetil amino de compostos eritromicina
JP5684474B2 (ja)	2006-09-11	2015-03-11	オセラセラピューティクス，インコーポレイテッド	胃腸の運動障害疾患の治療のためのモチリン受容体の大環状アンタゴニスト
MX2009005977A (es)	2006-12-05	2009-06-17	Pfizer	Polimorfos de motilida.
US20080287371A1 (en) *	2007-05-17	2008-11-20	Tranzyme Pharma Inc.	Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
ES2609845T3 (es)	2011-07-29	2017-04-24	Cambridge Epigenetix Limited	Métodos para la detección de modificación de nucleótidos
ES2786984T3 (es)	2012-11-30	2020-10-14	Cambridge Epigenetix Ltd	Agente oxidante para nucleótidos modificados
CN115057794B (zh) *	2022-07-07	2023-11-17	桂林理工大学	一种可见光诱导铈催化氧化酰胺去甲基化的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4518590A (en) *	1984-04-13	1985-05-21	Pfizer Inc.	9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
US4512982A (en) *	1984-04-13	1985-04-23	Pfizer Inc.	9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
DE3689758T2 (de) *	1985-08-31	1994-08-18	Kitasato Inst	Erythromycinderivat und Verfahren zu dessen Herstellung.
US5008249A (en) *	1985-08-31	1991-04-16	Kitasato Kenkyusho	Therapeutic method of stimulating digestive tract contractile motion in mammals
US5106961A (en) *	1987-05-26	1992-04-21	Eli Lilly And Company	Erythromycin ring-contracted derivatives
US4958010A (en) *	1988-02-16	1990-09-18	Bristol-Myers Company	Epipodophyllotoxin glucoside lactam derivatives
US4920102A (en) *	1988-04-18	1990-04-24	Eli Lilly And Company	Method for treating gastrointestinal disorders
US5202434A (en) *	1991-04-05	1993-04-13	Merck & Co., Inc.	8a-aza-8a-homoerythromycin lactams
US5189159A (en) *	1992-04-02	1993-02-23	Merck & Co., Inc.	8a-AZA-8a-homoerythromycin cyclic iminoethers

1992
- 1992-03-30 DE DE69211845T patent/DE69211845T2/de not_active Expired - Fee Related
- 1992-03-30 AT AT92911585T patent/ATE139697T1/de not_active IP Right Cessation
- 1992-03-30 US US08/108,659 patent/US5538961A/en not_active Expired - Fee Related
- 1992-03-30 ES ES92911585T patent/ES2091471T3/es not_active Expired - Lifetime
- 1992-03-30 JP JP4511370A patent/JPH06509326A/ja active Pending
- 1992-03-30 CA CA002103913A patent/CA2103913A1/en not_active Abandoned
- 1992-03-30 WO PCT/US1992/002590 patent/WO1992018134A1/en not_active Ceased
- 1992-03-30 EP EP92911585A patent/EP0579770B1/en not_active Expired - Lifetime
- 1992-03-30 KR KR1019930703026A patent/KR100222014B1/ko not_active Expired - Fee Related
- 1992-03-30 DK DK92911585.5T patent/DK0579770T3/da active
- 1992-03-30 AU AU19103/92A patent/AU663089B2/en not_active Ceased
- 1992-04-02 IE IE921045A patent/IE73236B1/en not_active IP Right Cessation
- 1992-04-06 IL IL101504A patent/IL101504A/en not_active IP Right Cessation
- 1992-04-08 PT PT100357A patent/PT100357B/pt not_active IP Right Cessation
1996
- 1996-08-22 GR GR960402210T patent/GR3020853T3/el unknown

Also Published As

Publication number	Publication date
EP0579770A4 (pt)	1994-03-30
EP0579770B1 (en)	1996-06-26
GR3020853T3 (en)	1996-11-30
IE73236B1 (en)	1997-05-21
WO1992018134A1 (en)	1992-10-29
DK0579770T3 (da)	1996-11-04
DE69211845T2 (de)	1997-01-23
US5538961A (en)	1996-07-23
PT100357B (pt)	1999-06-30
KR100222014B1 (ko)	1999-10-01
IL101504A0 (en)	1992-12-30
IL101504A (en)	1998-04-05
DE69211845D1 (de)	1996-08-01
AU663089B2 (en)	1995-09-28
JPH06509326A (ja)	1994-10-20
EP0579770A1 (en)	1994-01-26
ATE139697T1 (de)	1996-07-15
CA2103913A1 (en)	1992-10-10
ES2091471T3 (es)	1996-11-01
AU1910392A (en)	1992-11-17
IE921045A1 (en)	1992-10-21

Legal Events

Date

Code

Title

Description

1993-07-30

BB1A

Laying open of patent application

Effective date: 19930317

1999-06-30

FG3A

Patent granted, date of granting

Effective date: 19990331

2003-12-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20030930

Publication	Publication Date	Title
DK0579770T3 (da)	1996-11-04	Makrocycliske lactamprokinetika
BR9408246A (pt)	1997-05-27	Composto derivado de 3-azabicicloalcano N-substituído
IL99775A0 (en)	1992-08-18	Antimicrobial agents containing substituted 2-cyclohexan-1-yl-amino derivatives,certain such novel compounds and their preparation
AU2534288A (en)	1989-05-23	Heterocyclic compounds
IL97535A0 (en)	1992-06-21	Squalene synthetase inhibitor dioxabicyclo(1,2,3)octanes,their production and pharmaceutical compositions containing them
FI925415A0 (fi)	1992-11-27	Framstaellning av substituerade piperidiner
AU565519B2 (en)	1987-09-17	Pyridyl piperidinedione derivatives and their use as anti-arrhythmics
BR9206823A (pt)	1995-04-25	Preparação de piperidinas substituídas
IL75357A (en)	1992-05-25	Primycin components,process for the separation of the antibiotic complex and antibiotic pharmaceutical compositions containing them
NZ212658A (en)	1988-02-29	Phenylnaphthyridine derivatives and pharmaceutical compositions
IL101786A0 (en)	1992-12-30	Thiomarinol,processes for the preparation thereof,and pharmaceutical compositions containing the same
DE69029708D1 (de)	1997-02-27	Verfahren zur Herstellung von AZT(3'-azido-3'-desoxythymidin) und diebezüglichen Verbindungen
US5162542A (en)	1992-11-10	Substituted pyrazoline derivatives
SE9203824D0 (sv)	1992-12-18	Benzofuranylimidazole derivatives a process for the preparation and therapeutical compositions containing the same
DE59006419D1 (de)	1994-08-18	Benzylselenobenzamide von Anilinen und Benzylaminen.
GR3015706T3 (en)	1995-07-31	Benzylselenobenzamides of aminopyridines and picolylamines.
ES2052133T3 (es)	1994-07-01	Picolilselenio-benzamidas de aminopiridinas, anilinas y picolilaminas.
MX9305453A (es)	1994-05-31	Metodo para tratar infecciones virales.
IL99369A0 (en)	1992-08-18	Pharmaceutical compositions containing substituted 2-cyclohexene derivatives
FI911616A0 (fi)	1991-04-04	Substituerade 3-tia- eller 3-oxa-alkyl -flavoner, foerfarande foer deras framstaellning, deras anvaendning, pao dessa foereningar baserade laekemedel samt mellanprodukter.