PT100736A - Glicosfingolipidos e sua utilizacao - Google Patents

Glicosfingolipidos e sua utilizacao

Info

Publication number
PT100736A
PT100736A PT100736A PT10073692A PT100736A PT 100736 A PT100736 A PT 100736A PT 100736 A PT100736 A PT 100736A PT 10073692 A PT10073692 A PT 10073692A PT 100736 A PT100736 A PT 100736A
Authority
PT
Portugal
Prior art keywords
sphingoglycolipid
integer
glicosfingolipidos
chem
isopropyl
Prior art date
Application number
PT100736A
Other languages
English (en)
Other versions
PT100736B (pt
Inventor
Tatsuo Higa
Koji Akimoto
Yasuhiko Koezuka
Teruyuki Sakai
Masahiro Morita
Takenori Natori
Original Assignee
Kirin Brewery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery filed Critical Kirin Brewery
Publication of PT100736A publication Critical patent/PT100736A/pt
Publication of PT100736B publication Critical patent/PT100736B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT100736A 1991-08-29 1992-07-28 Glicosfingolipidos e sua utilizacao PT100736B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3244384A JPH0559081A (ja) 1991-08-29 1991-08-29 新規スフインゴ糖脂質、その製造法および使用

Publications (2)

Publication Number Publication Date
PT100736A true PT100736A (pt) 1993-09-30
PT100736B PT100736B (pt) 1999-04-30

Family

ID=17117885

Family Applications (1)

Application Number Title Priority Date Filing Date
PT100736A PT100736B (pt) 1991-08-29 1992-07-28 Glicosfingolipidos e sua utilizacao

Country Status (18)

Country Link
EP (1) EP0609437B1 (pt)
JP (2) JPH0559081A (pt)
KR (1) KR100220793B1 (pt)
AT (1) ATE181922T1 (pt)
AU (1) AU665536B2 (pt)
CA (1) CA2116442C (pt)
DE (1) DE69229557T2 (pt)
DK (1) DK0609437T3 (pt)
ES (1) ES2134213T3 (pt)
FI (1) FI105189B (pt)
GR (1) GR3030723T3 (pt)
HU (1) HU223839B1 (pt)
NO (1) NO180338C (pt)
PT (1) PT100736B (pt)
SG (1) SG44031A1 (pt)
TW (1) TW197446B (pt)
WO (1) WO1993005055A1 (pt)
ZA (1) ZA923239B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
TW261533B (pt) * 1992-07-16 1995-11-01 Kirin Brewery
EP0666268B1 (en) * 1992-10-22 2000-04-19 Kirin Beer Kabushiki Kaisha Novel sphingoglycolipid and use thereof
EP0694558B1 (en) * 1993-04-15 1999-01-27 Kirin Beer Kabushiki Kaisha Novel sphingoglycolipid and use thereof
TW555562B (en) 1996-12-27 2003-10-01 Kirin Brewery Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof
TW575420B (en) * 1997-09-22 2004-02-11 Kirin Brewery Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides
AU782539B2 (en) * 2000-01-14 2005-08-04 Meiji Dairies Corporation Antigen-specific IgE antibody production inhibitors
JP2002030093A (ja) * 2000-03-13 2002-01-29 Nof Corp グリコシルセラミドの精製方法
DE60215530T2 (de) * 2001-08-16 2007-05-31 Daiichi Asubio Pharma Co., Ltd. Neues glykolipid, und heilmittel für autoimmunerkrankungen, das dieses als wirkstoff enthält
WO2004026318A1 (ja) * 2002-09-20 2004-04-01 Kirin Beer Kabushiki Kaisha α-グリコシルセラミドを有効成分とするＣ型肝炎ウイルス抑制剤
JP4585172B2 (ja) * 2003-01-31 2010-11-24 森永乳業株式会社 骨形成促進剤
WO2004072091A1 (ja) 2003-02-14 2004-08-26 Daiichi Suntory Pharma Co., Ltd. 糖脂質誘導体及びその製造法並びにそれらの合成中間体及びその製造法
JP4753089B2 (ja) * 2004-12-20 2011-08-17 株式会社岡安商店 体内脂肪の分解促進作用を有する組成物及びそれを含有する食品又は食品配合剤
JP2007070311A (ja) * 2005-09-09 2007-03-22 Gunma Univ α−ガラクトシルセラミドからなる感染症予防剤及び感染症治療剤
EP1776963A1 (en) 2005-10-19 2007-04-25 Gbf-Gesellschaft Für Biotechnologische Forschung Mbh Hexosylceramides as adjuvants and their uses in pharmaceutical compositions
WO2008047174A1 (en) * 2006-10-18 2008-04-24 Centre National De La Recherche Scientifique Alpha-galactosylceramide analogs, their methods of manufacture, intermediate compounds useful in these methods, and pharmaceutical compositions containing them
KR100868959B1 (ko) * 2006-12-30 2008-11-17 재단법인서울대학교산학협력재단 알파-갈락토실세라마이드 유도체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는면역보조용 약학적 조성물
US7959907B2 (en) 2007-02-21 2011-06-14 Vib Vzw Method of treating cancer by combination therapy using TNF and alpha-galactosylceramide
JP4995172B2 (ja) * 2008-10-10 2012-08-08 壽製薬株式会社 糖脂質誘導体、その製造方法並びにそれを有効成分とする医薬
LT2939683T (lt) 2009-02-16 2017-03-27 Cerenis Therapeutics Holding Sa Apolipoproteino a-i mimetikai
JP5025692B2 (ja) * 2009-07-06 2012-09-12 壽製薬株式会社 糖脂質誘導体の製造方法
JP5095683B2 (ja) * 2009-07-06 2012-12-12 壽製薬株式会社 新規糖脂質誘導体及びこれを有効成分とする製剤
JP2010254718A (ja) * 2010-08-13 2010-11-11 Morinaga Milk Ind Co Ltd 骨形成促進剤
CN107011359A (zh) 2010-10-18 2017-08-04 塞伦尼斯医疗控股有限公司 可用于胆固醇动员的化合物、组合物和方法
WO2012074116A1 (ja) 2010-12-02 2012-06-07 独立行政法人理化学研究所 アロNKT細胞を用いた免疫療法およびそのためのT細胞抗原受容体（TCR）遺伝子のα鎖領域が均一なVα-Jαに再構成されている細胞および該細胞由来NKT細胞のバンキング
US9464105B2 (en) 2012-08-03 2016-10-11 Riken Hydroxylated KRN7000 analogue and use thereof
WO2014053482A1 (en) 2012-10-03 2014-04-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the prophylactic treatment of bacterial superinfections post-influenza with invariant nkt cell agonists
ES2719255T3 (es) 2012-11-21 2019-07-09 Inst Nat Sante Rech Med Métodos para determinar el riesgo de enfermedad aguda del injerto contra el hospedador
WO2017207040A1 (en) 2016-06-01 2017-12-07 Vib Vzw ANTI-CANCER THERAPY USING A LEPTIN ANTAGONIST AND AN iNKT-CELL ACTIVATOR
KR102328367B1 (ko) * 2019-11-05 2021-11-18 한국해양과학기술원 아젤록심 d를 유효성분으로 함유하는 방사선 민감성 증진용 조성물
KR20230117371A (ko) 2020-12-04 2023-08-08 가부시키가이샤 레그이뮨 체내 동태가 개선된 CD1d 리간드 화합물 함유 리포솜 제제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6157594A (ja) * 1984-08-30 1986-03-24 Suntory Ltd ガラクトスフインゴ脂質及びその製造法
JP2588729B2 (ja) * 1987-10-05 1997-03-12 塩野義製薬株式会社 スフィンゴシン誘導体
DE3840044A1 (de) * 1988-11-27 1990-06-07 Behringwerke Ag Glykosphingolipide mit kopplungsfaehiger gruppe im sphingoidanteil, ihre herstellung und verwendung
JP3068910B2 (ja) * 1990-11-08 2000-07-24 麒麟麦酒株式会社 新規スフィンゴ糖脂質、その製造法および使用

Also Published As

Publication number Publication date
NO940598L (pt) 1994-04-27
ZA923239B (en) 1993-05-05
JP2774194B2 (ja) 1998-07-09
ATE181922T1 (de) 1999-07-15
NO180338C (no) 1997-04-02
FI940851A0 (fi) 1994-02-23
WO1993005055A1 (fr) 1993-03-18
DE69229557T2 (de) 1999-11-25
NO940598D0 (no) 1994-02-22
NO180338B (no) 1996-12-23
HU9400596D0 (en) 1994-05-30
DK0609437T3 (da) 2000-01-31
EP0609437B1 (en) 1999-07-07
GR3030723T3 (en) 1999-11-30
EP0609437A1 (en) 1994-08-10
AU1666492A (en) 1993-04-05
EP0609437A4 (en) 1994-08-24
HUT70435A (en) 1995-10-30
KR100220793B1 (ko) 1999-10-01
ES2134213T3 (es) 1999-10-01
CA2116442C (en) 2000-09-05
SG44031A1 (en) 1997-11-14
DE69229557D1 (de) 1999-08-12
JPH0559081A (ja) 1993-03-09
FI105189B (fi) 2000-06-30
PT100736B (pt) 1999-04-30
AU665536B2 (en) 1996-01-11
CA2116442A1 (en) 1993-03-18
TW197446B (pt) 1993-01-01
HK1009967A1 (en) 1999-09-17
HU223839B1 (hu) 2005-02-28
FI940851A7 (fi) 1994-02-23

Similar Documents

Publication Publication Date Title
PT100736A (pt) Glicosfingolipidos e sua utilizacao
CA2319005A1 (en) 2-pyridylmethylamine derivatives useful as fungicides
CA2043071A1 (en) Heterocyclic compounds
EP0632031A4 (pt)
PL309874A1 (en) Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives
SG49607A1 (en) 1-methylcarbapenem derivatives and process for preparation thereof
IL92240A0 (en) Serine analogs of bu-3608 antibodies,their preparation and pharmaceutical compositions containing them
EP0549797A4 (en) Isoxazole compound, pharmaceutically acceptable salt thereof, and medicinal use thereof
GB8826595D0 (en) Active compounds
HUT50337A (en) Process for producing benzoxazine derivatives and pharmaceutical compositions comprising the compounds
EP0347815A3 (en) Cleaner for thermostatic water bath
HUT51603A (en) Herbicide and plant growth regulating preparation containing alkyl- and alkenyl-sulfonyl-urea compounds substituted by heterocyclic radical as well as process for producing the active agents
GB8811036D0 (en) Chemical compounds
TW350757B (en) Benzisoxazole derivatives and pesticidal compositions containing them
HU903092D0 (en) Process for the preparation of buten-carboxylic acid derivatives and pharmaceutical compositions containing such compounds
WO1993025568A3 (en) Antihypercholesterolemic compounds and related pharmaceutical compositions and methods of use
EP0555479A4 (pt)
DE69018335D1 (de) Imidazochinolonderivate.
ATE112682T1 (de) Isocarbacyclinderivate enthaltende antidiabetika.
PT88462A (pt) Process for the preparation of macrolide compounds and of compositions containing them
EP0273357A3 (en) Fluorine-containing macrolide compounds, pharmaceutical compositions comprising the same and their use for the manufacture of medicaments
JPS56122372A (en) Prostaglandin i2 derivative

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19930507

FG3A Patent granted, date of granting

Effective date: 19990204

PC4A Transfer of assignment

Owner name: KIRIN PHARMA KABUSHIKI KAISHA, JP

Effective date: 20080718

PD4A Change of proprietorship

Owner name: KIRIN HOLDINGS KABUSHIKI KAISHA, JP

Effective date: 20080718

TE4A Change of address (patent)

Owner name: KIRIN BEER KABUSHIKI KAISHA, JP

Effective date: 20080718

PC4A Transfer of assignment

Owner name: KYOWA HAKKO KIRIN CO., LTD., JP

Effective date: 20090820

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20140204