PT1017413E - Formulacoes liquidas de interferao (beta) - Google Patents

Formulacoes liquidas de interferao (beta)

Info

Publication number
PT1017413E
PT1017413E PT98950074T PT98950074T PT1017413E PT 1017413 E PT1017413 E PT 1017413E PT 98950074 T PT98950074 T PT 98950074T PT 98950074 T PT98950074 T PT 98950074T PT 1017413 E PT1017413 E PT 1017413E
Authority
PT
Portugal
Prior art keywords
beta
buffered
formulations
hsa
contain
Prior art date
Application number
PT98950074T
Other languages
English (en)
Inventor
Thomas Siklosi
Hans Hofer
Michael Tschope
Peter Schroeder
Original Assignee
Rentschler Biotech Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8227392&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1017413(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rentschler Biotech Gmbh filed Critical Rentschler Biotech Gmbh
Publication of PT1017413E publication Critical patent/PT1017413E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Gyroscopes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
PT98950074T 1997-09-23 1998-09-23 Formulacoes liquidas de interferao (beta) PT1017413E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97116562 1997-09-23

Publications (1)

Publication Number Publication Date
PT1017413E true PT1017413E (pt) 2003-02-28

Family

ID=8227392

Family Applications (2)

Application Number Title Priority Date Filing Date
PT02004883T PT1224940E (pt) 1997-09-23 1998-09-23 Formulacoes liquidas de intrferao beta
PT98950074T PT1017413E (pt) 1997-09-23 1998-09-23 Formulacoes liquidas de interferao (beta)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT02004883T PT1224940E (pt) 1997-09-23 1998-09-23 Formulacoes liquidas de intrferao beta

Country Status (13)

Country Link
US (2) US6923956B1 (pt)
EP (3) EP1017413B2 (pt)
JP (1) JP4293497B2 (pt)
KR (2) KR100826621B1 (pt)
AT (2) ATE274917T1 (pt)
AU (1) AU741300B2 (pt)
CA (1) CA2304808C (pt)
DE (2) DE59811910D1 (pt)
DK (1) DK1017413T4 (pt)
ES (2) ES2181281T5 (pt)
IL (3) IL135186A0 (pt)
PT (2) PT1224940E (pt)
WO (1) WO1999015193A1 (pt)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
GB9526733D0 (en) 1995-12-30 1996-02-28 Delta Biotechnology Ltd Fusion proteins
US20030190307A1 (en) 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
DK1017413T4 (da) † 1997-09-23 2008-03-25 Rentschler Biotech Gmbh Flydende formulering af interferon-beta
US6926898B2 (en) 2000-04-12 2005-08-09 Human Genome Sciences, Inc. Albumin fusion proteins
US6946134B1 (en) 2000-04-12 2005-09-20 Human Genome Sciences, Inc. Albumin fusion proteins
US6495534B2 (en) * 2000-05-15 2002-12-17 Pharmacia & Upjohn Spa Stabilized aqueous suspensions for parenteral use
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
US7507413B2 (en) 2001-04-12 2009-03-24 Human Genome Sciences, Inc. Albumin fusion proteins
WO2005003296A2 (en) 2003-01-22 2005-01-13 Human Genome Sciences, Inc. Albumin fusion proteins
CA2841097A1 (en) 2001-12-21 2003-07-24 Human Genome Sciences, Inc. Albumin and g-csf fusion proteins
WO2004007520A2 (en) * 2002-07-12 2004-01-22 Medarex, Inc. Methods and compositions for preventing oxidative degradation of proteins
TWI272948B (en) * 2003-05-01 2007-02-11 Ares Trading Sa HSA-free stabilized interferon liquid formulations
US8277810B2 (en) 2003-11-04 2012-10-02 Novartis Vaccines & Diagnostics, Inc. Antagonist anti-CD40 antibodies
JP4845741B2 (ja) * 2003-12-23 2011-12-28 ファルマシア コーポレーション 安定な成長ホルモン液体製剤
US7879320B2 (en) * 2004-05-17 2011-02-01 Ares Trading S.A. Hydrogel interferon formulations
US7731948B2 (en) 2004-06-01 2010-06-08 Ares Trading S.A. Stabilized interferon liquid formulations
EA012281B1 (ru) * 2004-06-01 2009-08-28 Арес Трейдинг С.А. Способ стабилизации белков
KR101191536B1 (ko) * 2004-06-01 2012-10-15 아레스 트레이딩 에스.에이. 안정화된 인터페론 액상 제제
DE602005011321D1 (de) * 2004-11-10 2009-01-08 Novartis Vaccines & Diagnostic Deamidiertes interferon-beta
TW200640492A (en) * 2005-02-21 2006-12-01 Lg Life Sciences Ltd Sustained release composition of protein drug
US20080219952A1 (en) * 2005-08-26 2008-09-11 Ares Trading S.A. Process For the Preparation of Glycosylated Interferon Beta
TW200806317A (en) * 2006-03-20 2008-02-01 Wyeth Corp Methods for reducing protein aggregation
DE102007050165B4 (de) * 2007-10-19 2010-06-17 Stiftung Tierärztliche Hochschule Hannover Stabilisierte Lösung, Verfahren zu deren Herstellung sowie deren Verwendung und Arzneimittel in Form einer stabilisierten Lösung
RS52417B (sr) * 2007-12-20 2013-02-28 Merck Serono S.A. Formulacije peg-interferona-beta
US9119866B2 (en) * 2008-04-08 2015-09-01 Huiru Wang Glycan-based drugs, therapies and biomarkers
DE102008060960A1 (de) * 2008-12-06 2010-06-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Optische Füllstandsmessung
DE102009032179A1 (de) 2009-07-07 2011-01-13 Biogenerix Ag Verfahren zur Reinigung von Interferon beta
KR101303388B1 (ko) * 2010-10-26 2013-09-03 한미사이언스 주식회사 지속형 인터페론 알파 결합체의 액상 제제
AR083847A1 (es) 2010-11-15 2013-03-27 Novartis Ag Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40
US8506797B2 (en) * 2011-04-10 2013-08-13 Therapeutic Proteins International, LLC Downstream bioprocessing device
US8852435B2 (en) * 2011-11-29 2014-10-07 Therapeutics Proteins International, LLC Purification and separation treatment assembly (PASTA) for biological products
US20140004131A1 (en) 2012-05-04 2014-01-02 Novartis Ag Antibody formulation
ES2806946T3 (es) * 2012-10-26 2021-02-19 Lupin Atlantis Holdings Sa Composición farmacéutica estable de la proteína de fusión TNFR:Fc etanercept
WO2014078627A1 (en) * 2012-11-19 2014-05-22 Merck Sharp & Dohme Corp. Liquid formulations for tnfr:fc fusion proteins
FI126979B (en) 2016-02-29 2017-09-15 Faron Pharmaceuticals Oy Lyophilized pharmaceutical formulation and its use

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU538665B2 (en) 1979-10-30 1984-08-23 Juridical Foundation, Japanese Foundation For Cancer Research Human interferon dna
DK170476B1 (da) 1980-04-03 1995-09-11 Biogen Inc Rekombinant DNA-molekyle, uni-cellulær vært transformeret med mindst ét rekombinant DNA-molekyle, fremgangsmåde til transformering af en uni-cellulær vært, samt fremgangsmåder til fremstilling af et polpeptid, der udviser den immunologiske eller biologiske aktivitet af human beta-interferon
WO1982002715A1 (fr) 1981-02-04 1982-08-19 Sugano Haruo Gene d'interferon (beta)humain
EP0082481B2 (en) † 1981-12-23 1990-09-12 Schering Corporation Stabilised alpha-interferon formulations and their preparation
AU1234383A (en) 1982-03-17 1983-09-22 Inter-Yeda Ltd. Interferon stabilised with polyvinyl-pyrrolidone
US4992271A (en) 1982-09-23 1991-02-12 Cetus Corporation Formulation for lipophilic IL-2 proteins
JPS59181224A (ja) † 1983-03-29 1984-10-15 Sumitomo Chem Co Ltd 安定なインタ−フエロン製剤の製法
US4816440A (en) 1985-09-26 1989-03-28 Cetus Corporation Stable formulation of biologically active proteins for parenteral injection
CA1294215C (en) 1986-10-27 1992-01-14 Ze'ev Shaked Pharmaceutical compositions of recombinant beta-interferon and formulation processes
US5183746A (en) 1986-10-27 1993-02-02 Schering Aktiengesellschaft Formulation processes for pharmaceutical compositions of recombinant β-
EP0284249A1 (en) 1987-03-13 1988-09-28 Interferon Sciences, Inc. Lyophilized lymphokine composition
DE3712564A1 (de) 1987-04-14 1988-11-24 Bioferon Biochem Substanz Verfahren zur konstruktion einer animalen zellinie fuer die herstellung von humanem interferon-beta
US4895716A (en) † 1987-06-09 1990-01-23 Biogen, Inc. Stabilized formulations of gamma interferons
US5151265A (en) * 1987-11-03 1992-09-29 Genentech, Inc. Gamma interferon formulation
US5004605A (en) 1987-12-10 1991-04-02 Cetus Corporation Low pH pharmaceutical compositions of recombinant β-interferon
EP0374257B1 (en) * 1988-05-06 1994-08-31 Toray Industries, Inc. STABLE INTERFERON $g(b) COMPOSITION
US5272135A (en) † 1991-03-01 1993-12-21 Chiron Ophthalmics, Inc. Method for the stabilization of methionine-containing polypeptides
DE4128319A1 (de) * 1991-08-27 1993-03-04 Bioferon Biochem Substanz Neues rekombinantes human-ifn-beta, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische zubereitungen
US5358708A (en) * 1993-01-29 1994-10-25 Schering Corporation Stabilization of protein formulations
JPH06247870A (ja) 1993-02-23 1994-09-06 Ajinomoto Co Inc インターロイキン−６を含有する医薬製剤
IT1272252B (it) * 1994-05-16 1997-06-16 Applied Research Systems Formulazioni liquide di interferone beta
DE69729880T3 (de) 1996-12-24 2012-05-10 Biogen Idec Ma Inc. Stabile flüssige interferon-zubereitungen
DK1017413T4 (da) † 1997-09-23 2008-03-25 Rentschler Biotech Gmbh Flydende formulering af interferon-beta

Also Published As

Publication number Publication date
DE59811910D1 (de) 2004-10-07
ATE274917T1 (de) 2004-09-15
EP1017413B1 (de) 2002-09-25
US8337826B2 (en) 2012-12-25
KR20060088910A (ko) 2006-08-07
ES2223017T5 (es) 2010-10-15
ATE224726T1 (de) 2002-10-15
EP1426058A3 (de) 2004-07-28
DE59805732D1 (de) 2002-10-31
AU741300B2 (en) 2001-11-29
KR20010015599A (ko) 2001-02-26
CA2304808A1 (en) 1999-04-01
EP1224940A1 (de) 2002-07-24
JP4293497B2 (ja) 2009-07-08
EP1426058A2 (de) 2004-06-09
ES2181281T3 (es) 2003-02-16
AU9627698A (en) 1999-04-12
JP2001517635A (ja) 2001-10-09
DK1017413T3 (da) 2003-02-03
IL135186A0 (en) 2001-05-20
PT1224940E (pt) 2005-01-31
EP1224940A8 (de) 2002-11-20
US20050186177A1 (en) 2005-08-25
US6923956B1 (en) 2005-08-02
WO1999015193A1 (de) 1999-04-01
EP1017413B2 (de) 2007-11-07
EP1224940B2 (de) 2010-08-11
EP1224940B1 (de) 2004-09-01
ES2181281T5 (es) 2008-04-16
KR100826621B1 (ko) 2008-05-02
ES2223017T3 (es) 2005-02-16
EP1017413A1 (de) 2000-07-12
IL135186A (en) 2012-12-31
CA2304808C (en) 2011-03-22
DK1017413T4 (da) 2008-03-25
KR100711990B1 (ko) 2007-05-02
IL211048A (en) 2012-12-31

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