PT101847A - Peptido substituido derivado de lisina e prolina - Google Patents
Peptido substituido derivado de lisina e prolina Download PDFInfo
- Publication number
- PT101847A PT101847A PT10184796A PT10184796A PT101847A PT 101847 A PT101847 A PT 101847A PT 10184796 A PT10184796 A PT 10184796A PT 10184796 A PT10184796 A PT 10184796A PT 101847 A PT101847 A PT 101847A
- Authority
- PT
- Portugal
- Prior art keywords
- prepd
- starting materials
- large scale
- transferase inhibitor
- novel peptide
- Prior art date
Links
- 108010007859 Lisinopril Proteins 0.000 title abstract 2
- RLAWWYSOJDYHDC-BZSNNMDCSA-N lisinopril Chemical compound C([C@H](N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(O)=O)C(O)=O)CC1=CC=CC=C1 RLAWWYSOJDYHDC-BZSNNMDCSA-N 0.000 title abstract 2
- 229960002394 lisinopril Drugs 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 108010064733 Angiotensins Proteins 0.000 title 1
- 102000015427 Angiotensins Human genes 0.000 title 1
- 229940123468 Transferase inhibitor Drugs 0.000 title 1
- 239000007858 starting material Substances 0.000 title 1
- 239000003558 transferase inhibitor Substances 0.000 title 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9500770A HU214581B (hu) | 1995-03-14 | 1995-03-14 | N2-(1S)-(1-/Etoxi-karbonil/-3-fenil-propil)-N6-(trifluor-acetil)-(L)-lizil-(L)-prolin-benzil-észter és eljárás előállítására |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT101847A true PT101847A (pt) | 1996-09-30 |
| PT101847B PT101847B (pt) | 1998-04-30 |
Family
ID=10986628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT10184796A PT101847B (pt) | 1995-03-14 | 1996-03-08 | Peptido substituido derivado de lisina e prolina |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JP3699769B2 (pt) |
| AT (1) | AT406372B (pt) |
| DK (1) | DK175858B1 (pt) |
| ES (1) | ES2099684B1 (pt) |
| HU (2) | HU214579B (pt) |
| PT (1) | PT101847B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL136271A (en) * | 1998-09-22 | 2005-06-19 | Kaneka Corp | Process for the preparation of n<2>-(1(s)-carboxy-3-phenylpropyl)-l-lysyl-l-proline |
| CN109422702B (zh) * | 2017-08-30 | 2023-04-18 | 上海科胜药物研发有限公司 | 赖诺普利中间体及其纯化方法 |
| CN109422797B (zh) * | 2017-08-30 | 2023-12-19 | 上海科胜药物研发有限公司 | 一种赖诺普利中间体的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2028812T3 (es) * | 1986-03-27 | 1992-07-16 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Un procedimiento para la preparacion de un derivado de n2-(1-carboxi-3-oxo-3-fenilpropil)-l-lisina. |
| JPH01254651A (ja) * | 1988-04-04 | 1989-10-11 | Kanegafuchi Chem Ind Co Ltd | N↑2−(1−カルボキシ−3−フエニルプロピル)−l−リジン誘導体及び該化合物を用いるリジノプリルの製造法 |
-
1995
- 1995-03-14 HU HU9702176A patent/HU214579B/hu unknown
- 1995-03-14 HU HU9500770A patent/HU214581B/hu unknown
-
1996
- 1996-03-08 PT PT10184796A patent/PT101847B/pt not_active IP Right Cessation
- 1996-03-11 AT AT45796A patent/AT406372B/de not_active IP Right Cessation
- 1996-03-12 DK DK28696A patent/DK175858B1/da not_active IP Right Cessation
- 1996-03-13 ES ES9600609A patent/ES2099684B1/es not_active Expired - Fee Related
- 1996-03-14 JP JP05733896A patent/JP3699769B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08253497A (ja) | 1996-10-01 |
| HUT75716A (en) | 1997-05-28 |
| DK175858B1 (da) | 2005-04-11 |
| HU214581B (hu) | 1998-04-28 |
| PT101847B (pt) | 1998-04-30 |
| HU9500770D0 (en) | 1995-05-29 |
| ES2099684A1 (es) | 1997-05-16 |
| AT406372B (de) | 2000-04-25 |
| HU214579B (hu) | 1998-04-28 |
| JP3699769B2 (ja) | 2005-09-28 |
| HU9702176D0 (en) | 1998-01-28 |
| ATA45796A (de) | 1999-09-15 |
| DK28696A (da) | 1996-09-15 |
| ES2099684B1 (es) | 1998-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19960517 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19980127 |
|
| MM4A | Annulment/lapse due to non-payment of fees;searched & examined patent |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20100908 |