PT1283907E - Metodo para o diagnostico de cancros - Google Patents
Metodo para o diagnostico de cancrosInfo
- Publication number
- PT1283907E PT1283907E PT01928158T PT01928158T PT1283907E PT 1283907 E PT1283907 E PT 1283907E PT 01928158 T PT01928158 T PT 01928158T PT 01928158 T PT01928158 T PT 01928158T PT 1283907 E PT1283907 E PT 1283907E
- Authority
- PT
- Portugal
- Prior art keywords
- diagnosis
- channels
- cancers
- diagnosing
- rna
- Prior art date
Links
- 238000003745 diagnosis Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229920002477 rna polymer Polymers 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 108010017842 Telomerase Proteins 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 210000002381 plasma Anatomy 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00111370A EP1158055A1 (fr) | 2000-05-26 | 2000-05-26 | Méthode pour le diagnostic de cancers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1283907E true PT1283907E (pt) | 2005-01-31 |
Family
ID=8168848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT01928158T PT1283907E (pt) | 2000-05-26 | 2001-05-16 | Metodo para o diagnostico de cancros |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7163789B2 (pt) |
| EP (2) | EP1158055A1 (pt) |
| AT (1) | ATE275642T1 (pt) |
| AU (1) | AU5502101A (pt) |
| DE (1) | DE60105411T2 (pt) |
| ES (1) | ES2227178T3 (pt) |
| PT (1) | PT1283907E (pt) |
| WO (1) | WO2001090409A1 (pt) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6607898B1 (en) | 1996-03-26 | 2003-08-19 | Oncomedx, Inc. | Method for detection of hTR and hTERT telomerase-associated RNA in plasma or serum |
| US20030158673A1 (en) * | 2002-02-16 | 2003-08-21 | Ingene Institut Fur Genetische Medizin Gmbh | Method for creating a blood bank with associated data bank |
| ITMI20022743A1 (it) | 2002-12-23 | 2004-06-24 | Ist Naz Stud Cura Dei Tumori | Metodo per la determinazione del rischio di comparsa, della presenza o del decorso di malattie tumorali. |
| EP1528107B1 (fr) * | 2003-10-29 | 2006-11-22 | Maurice Stroun | Méthode pour le diagnostic de cancers |
| ES2313143T3 (es) | 2005-04-06 | 2009-03-01 | Maurice Stroun | Metodo para el diagnostico de cancer mediante la deteccion de adn y arn circulantes. |
| US8768629B2 (en) * | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| WO2007137187A2 (en) | 2006-05-18 | 2007-11-29 | Molecular Profiling Institute, Inc. | System and method for determining individualized medical intervention for a disease state |
| US8614057B2 (en) * | 2008-06-12 | 2013-12-24 | The Invention Science Fund I, Llc | Methods for collecting and detecting oligonucleotides |
| US8252528B2 (en) * | 2008-06-12 | 2012-08-28 | The Invention Science Fund I, Llc | Methods, compositions, and kits for collecting and detecting oligonucleotides |
| US8252529B2 (en) * | 2008-06-12 | 2012-08-28 | The Invention Science Fund I, Llc | Methods for collecting and detecting oligonucleotides |
| CA2743211A1 (en) | 2008-11-12 | 2010-05-20 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Methods and systems of using exosomes for determining phenotypes |
| US9128101B2 (en) | 2010-03-01 | 2015-09-08 | Caris Life Sciences Switzerland Holdings Gmbh | Biomarkers for theranostics |
| WO2011127219A1 (en) | 2010-04-06 | 2011-10-13 | Caris Life Sciences Luxembourg Holdings | Circulating biomarkers for disease |
| SG10202008532PA (en) | 2010-11-30 | 2020-10-29 | Univ Hong Kong Chinese | Detection of genetic or molecular aberrations associated with cancer |
| WO2013052168A2 (en) * | 2011-05-26 | 2013-04-11 | Georgetown University | Detection aib1-delta 4 protein |
| US20160040229A1 (en) | 2013-08-16 | 2016-02-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US10876152B2 (en) | 2012-09-04 | 2020-12-29 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| DE202013012824U1 (de) | 2012-09-04 | 2020-03-10 | Guardant Health, Inc. | Systeme zum Erfassen von seltenen Mutationen und einer Kopienzahlvariation |
| US11913065B2 (en) | 2012-09-04 | 2024-02-27 | Guardent Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| ES2660989T3 (es) | 2013-12-28 | 2018-03-27 | Guardant Health, Inc. | Métodos y sistemas para detectar variantes genéticas |
| US11302416B2 (en) | 2015-09-02 | 2022-04-12 | Guardant Health | Machine learning for somatic single nucleotide variant detection in cell-free tumor nucleic acid sequencing applications |
| US12540351B2 (en) | 2015-09-02 | 2026-02-03 | Guardant Health, Inc. | Identification of somatic mutations versus germline variants for cell-free DNA variant calling applications |
| CN117174167A (zh) | 2015-12-17 | 2023-12-05 | 夸登特健康公司 | 通过分析无细胞dna确定肿瘤基因拷贝数的方法 |
| US9850523B1 (en) | 2016-09-30 | 2017-12-26 | Guardant Health, Inc. | Methods for multi-resolution analysis of cell-free nucleic acids |
| KR20240155386A (ko) | 2016-09-30 | 2024-10-28 | 가던트 헬쓰, 인크. | 무세포 핵산의 다중-해상도 분석 방법 |
| US10907211B1 (en) | 2017-02-16 | 2021-02-02 | Quantgene Inc. | Methods and compositions for detecting cancer biomarkers in bodily fluids |
| WO2020047553A1 (en) | 2018-08-31 | 2020-03-05 | Guardant Health, Inc. | Genetic variant detection based on merged and unmerged reads |
| CA3126428A1 (en) | 2019-01-31 | 2020-08-06 | Guardant Health, Inc. | Compositions and methods for isolating cell-free dna |
| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
| US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4699877A (en) | 1982-11-04 | 1987-10-13 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5274087A (en) | 1986-08-13 | 1993-12-28 | Molecular Diagnostics, Inc. | cDNA coding for carcinoembryonic antigen (CEA) |
| DE3717212A1 (de) | 1987-05-22 | 1988-12-08 | Viktor Dr Dr Med Balazs | Verfahren zur untersuchung einer azellularen biologischen fluessigkeit auf zellulare onkogen-transkripte bzw. deren fragmente |
| US5124246A (en) | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| US4874858A (en) | 1988-03-28 | 1989-10-17 | The B. F. Goodrich Company | Triazine-containing multisilane coupling agents for coating glass fibers, for adhesives, and for protective coatings |
| US4999290A (en) | 1988-03-31 | 1991-03-12 | The Board Of Regents, The University Of Texas System | Detection of genomic abnormalities with unique aberrant gene transcripts |
| US5098890A (en) | 1988-11-07 | 1992-03-24 | Temple University-Of The Commonwealth System Of Higher Education | Antisence oligonucleotides to c-myb proto-oncogene and uses thereof |
| US5087617A (en) | 1989-02-15 | 1992-02-11 | Board Of Regents, The University Of Texas System | Methods and compositions for treatment of cancer using oligonucleotides |
| EP0458831A1 (de) | 1989-02-16 | 1991-12-04 | BALAZS, Viktor, Dr. Dr. med. | Malignitätstest (krebs-test) mit verwendung von der polymerasekettenreaktion |
| US5217889A (en) | 1990-10-19 | 1993-06-08 | Roninson Igor B | Methods and applications for efficient genetic suppressor elements |
| US5155018A (en) | 1991-07-10 | 1992-10-13 | Hahnemann University | Process and kit for isolating and purifying RNA from biological sources |
| WO1993017127A1 (en) | 1992-02-20 | 1993-09-02 | The State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University | Boomerand dna amplification |
| US5300635A (en) | 1993-02-01 | 1994-04-05 | University Of Iowa Research Foundation | Quaternary amine surfactants and methods of using same in isolation of nucleic acids |
| DE19681033D2 (de) * | 1995-11-16 | 1999-03-18 | Michael W Dahm | Verfahren zur Quantifizierung von Tumorzellen in einer Körperflüssigkeit und dazu geeignete Testkits |
| US5817461A (en) * | 1996-01-03 | 1998-10-06 | Hamilton Civic Hospitals Research Development Inc. | Methods and compositions for diagnosis of hyperhomocysteinemia |
| US6607898B1 (en) * | 1996-03-26 | 2003-08-19 | Oncomedx, Inc. | Method for detection of hTR and hTERT telomerase-associated RNA in plasma or serum |
| ES2347854T5 (es) | 1996-03-26 | 2014-07-24 | Michael S. Kopreski | Método que permite el uso de RNA extracelular extraído de plasma o suero para detectar, monitorizar o evaluar un cáncer |
| US6610839B1 (en) * | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
| CN1254376A (zh) * | 1996-10-01 | 2000-05-24 | 杰龙公司 | 端粒酶逆转录酶 |
| AU733610B2 (en) * | 1996-12-20 | 2001-05-17 | Geron Corporation | Methods for detecting and inhibiting the RNA component of telomerase |
| DE19757300A1 (de) * | 1997-12-22 | 1999-06-24 | Roche Diagnostics Gmbh | Nachweis von Harnblasenkarzinom in einer Urinprobe |
| DE19804372A1 (de) * | 1998-02-04 | 1999-08-05 | Michael W Dr Dr Dahm | Verfahren zur quantitativen Bestimmung von Tumorzellen in einer Körperflüssigkeit und dazu geeignete Testkits |
| WO1999041406A1 (en) * | 1998-02-16 | 1999-08-19 | University Of Maryland, Baltimore | Telomerase assay of body fluids for cancer screening and assessment of disease stage and prognosis |
| WO1999050407A1 (en) * | 1998-03-26 | 1999-10-07 | Kyowa Hakko Kogyo Co., Ltd. | Monoclonal antibody against human telomerase catalytic subunit |
-
2000
- 2000-05-26 EP EP00111370A patent/EP1158055A1/fr not_active Withdrawn
-
2001
- 2001-05-16 US US10/296,739 patent/US7163789B2/en not_active Expired - Lifetime
- 2001-05-16 AU AU55021/01A patent/AU5502101A/en not_active Abandoned
- 2001-05-16 ES ES01928158T patent/ES2227178T3/es not_active Expired - Lifetime
- 2001-05-16 EP EP01928158A patent/EP1283907B1/fr not_active Expired - Lifetime
- 2001-05-16 WO PCT/IB2001/000852 patent/WO2001090409A1/fr not_active Ceased
- 2001-05-16 AT AT01928158T patent/ATE275642T1/de active
- 2001-05-16 DE DE60105411T patent/DE60105411T2/de not_active Expired - Lifetime
- 2001-05-16 PT PT01928158T patent/PT1283907E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US7163789B2 (en) | 2007-01-16 |
| EP1283907A1 (fr) | 2003-02-19 |
| ES2227178T3 (es) | 2005-04-01 |
| EP1283907B1 (fr) | 2004-09-08 |
| EP1158055A1 (fr) | 2001-11-28 |
| US20040132019A1 (en) | 2004-07-08 |
| DE60105411D1 (de) | 2004-10-14 |
| DE60105411T2 (de) | 2005-09-22 |
| ATE275642T1 (de) | 2004-09-15 |
| WO2001090409A1 (fr) | 2001-11-29 |
| AU5502101A (en) | 2001-12-03 |
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