PT2220060T - Derivados de tetrahidrobenzotiazol - Google Patents

Derivados de tetrahidrobenzotiazol

Info

Publication number
PT2220060T
PT2220060T PT88458534T PT08845853T PT2220060T PT 2220060 T PT2220060 T PT 2220060T PT 88458534 T PT88458534 T PT 88458534T PT 08845853 T PT08845853 T PT 08845853T PT 2220060 T PT2220060 T PT 2220060T
Authority
PT
Portugal
Prior art keywords
tetrahydrobenzothiazole
derivatives
tetrahydrobenzothiazole derivatives
Prior art date
Application number
PT88458534T
Other languages
English (en)
Inventor
Stark* Holger
Matti Leppanen Jukka
Caroline Sasse Britta
Saur Oliver
Kottke Tim
Peter Hill Michael
Original Assignee
Motac Neuroscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Motac Neuroscience Ltd filed Critical Motac Neuroscience Ltd
Publication of PT2220060T publication Critical patent/PT2220060T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT88458534T 2007-10-31 2008-10-28 Derivados de tetrahidrobenzotiazol PT2220060T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0721332.5A GB0721332D0 (en) 2007-10-31 2007-10-31 Medicaments

Publications (1)

Publication Number Publication Date
PT2220060T true PT2220060T (pt) 2016-11-25

Family

ID=38834564

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88458534T PT2220060T (pt) 2007-10-31 2008-10-28 Derivados de tetrahidrobenzotiazol

Country Status (8)

Country Link
US (1) US8389555B2 (pt)
EP (1) EP2220060B1 (pt)
DK (1) DK2220060T3 (pt)
ES (1) ES2603880T3 (pt)
GB (1) GB0721332D0 (pt)
PL (1) PL2220060T3 (pt)
PT (1) PT2220060T (pt)
WO (1) WO2009056805A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2013005454A (es) * 2010-11-15 2013-06-24 Abbvie Inc Inhibidores de nampt y rock.
US10874669B2 (en) 2012-11-29 2020-12-29 Wayne State University Neuroprotective agents for treatment of neurodegenerative diseases
CA2885653A1 (en) 2012-11-29 2014-06-05 Wayne State University Neuroprotective agents for treatment of neurodegenerative diseases
CN104049475B (zh) * 2014-05-30 2017-12-12 江苏弘汉生物科技有限公司 具有防腐蚀功效的去除剂
WO2018021447A1 (ja) 2016-07-28 2018-02-01 塩野義製薬株式会社 ドーパミンd3受容体拮抗作用を有する含窒素縮環化合物
BR112020014875A2 (pt) 2018-01-26 2020-12-08 Shionogi & Co., Ltd. Composto cíclico condensado tendo antagonismo de receptor de dopamina d3
WO2019146740A1 (ja) 2018-01-26 2019-08-01 塩野義製薬株式会社 ドーパミンd3受容体拮抗作用を有する環式化合物
US11285147B2 (en) 2018-09-07 2022-03-29 Wayne State University Neuroprotective agents for treatment of neurodegenerative diseases
PL442046A1 (pl) * 2022-08-19 2024-02-26 Uniwersytet Jagielloński (E)-N-cynamoiloaminoalkanole o aktywności hamującej melanogenezę
CN115340508B (zh) * 2022-08-22 2024-06-25 南京医科大学 兼具d2受体激动和nmda受体拮抗作用的化合物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2731619A1 (fr) * 1995-03-14 1996-09-20 Logeais Labor Jacques Compositions pharmaceutiques contenant de la l-etrabamine, leurs utilisations et leurs procedes de preparation
RU2185372C2 (ru) * 1996-05-31 2002-07-20 Фармация Энд Апджон Компани Алкилзамещенные циклические амины в качестве селективных лигандов d3-допамина
AU2002322051A1 (en) * 2001-06-07 2002-12-16 Wayne State University Hybrid 2-aminotetralin and aryl-substituted piperazine compounds and their use in altering cns activity
US7741490B2 (en) 2004-03-19 2010-06-22 Dipharma S.P.A. Intermediates for the preparation of pramipexole

Also Published As

Publication number Publication date
EP2220060B1 (en) 2016-09-14
US20110046153A1 (en) 2011-02-24
EP2220060A1 (en) 2010-08-25
PL2220060T3 (pl) 2017-03-31
WO2009056805A1 (en) 2009-05-07
GB0721332D0 (en) 2007-12-12
US8389555B2 (en) 2013-03-05
DK2220060T3 (da) 2017-01-02
ES2603880T3 (es) 2017-03-01

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