PT2656843E - Ésteres de bendamustina e compostos relacionados e a sua utilização médica - Google Patents

Ésteres de bendamustina e compostos relacionados e a sua utilização médica Download PDF

Info

Publication number: PT2656843E
Authority: PT; Portugal
Prior art keywords: bendamustine; esters; related compounds; medical use; medical
Prior art date: 2012-04-26

Application number

PT121657282T

Other languages

English (en)

Inventor

Günther Bernhardt

Helmut Schickaneder

Armin Buschauer

Christian Schickaneder

Michael Limmert

Stefan Huber

Original Assignee

Helmut Schickaneder

Christians Schickaneder

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-04-26

Filing date

2012-04-26

Publication date

2015-04-14

2012-04-26 Application filed by Helmut Schickaneder, Christians Schickaneder filed Critical Helmut Schickaneder

2015-04-14 Publication of PT2656843E publication Critical patent/PT2656843E/pt

Links

YTKUWDBFDASYHO-UHFFFAOYSA-N bendamustine Chemical compound ClCCN(CCCl)C1=CC=C2N(C)C(CCCC(O)=O)=NC2=C1 YTKUWDBFDASYHO-UHFFFAOYSA-N 0.000 title 1
229960002707 bendamustine Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
150000002148 esters Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Materials For Medical Uses (AREA)

PT121657282T 2012-04-26 2012-04-26 Ésteres de bendamustina e compostos relacionados e a sua utilização médica PT2656843E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP12165728.2A EP2656843B1 (en)	2012-04-26	2012-04-26	Esters of bendamustine and related compounds, and medical use thereof

Publications (1)

Publication Number	Publication Date
PT2656843E true PT2656843E (pt)	2015-04-14

Family

ID=46045872

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT121657282T PT2656843E (pt)	2012-04-26	2012-04-26	Ésteres de bendamustina e compostos relacionados e a sua utilização médica

Country Status (8)

Country	Link
US (1)	US8809549B2 (pt)
EP (1)	EP2656843B1 (pt)
DK (1)	DK2656843T3 (pt)
ES (1)	ES2535511T3 (pt)
HR (1)	HRP20150436T1 (pt)
PL (1)	PL2656843T3 (pt)
PT (1)	PT2656843E (pt)
SI (1)	SI2656843T1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2694757T3 (es) *	2012-06-19	2018-12-27	Synbias Pharma Ag	Derivados de bendamustina y compuestos relacionados, y uso médico de los mismos para el tratamiento del cáncer
BR112015010501A2 (pt)	2012-11-12	2017-07-11	Ignyta Inc	composto, composição farmacêutica, nanopartículas, método para tratar câncer em um paciente e composição liofilizada
WO2015154630A1 (zh)	2014-04-10	2015-10-15	南京明德新药研发股份有限公司	作为PARP抑制剂的4H-吡唑并[1,5-α]苯并咪唑化合物的类似物
CA3013237A1 (en) *	2016-02-24	2017-08-31	Acesion Pharma Aps	Novel potassium channel inhibitors
SG11202003098WA (en)	2017-10-05	2020-05-28	Tube Pharmaceuticals Gmbh	Oral bendamustine formulations

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR072777A1 (es)	2008-03-26	2010-09-22	Cephalon Inc	Formas solidas de clorhidrato de bendamustina
EP2346836B1 (en) *	2008-10-08	2018-03-07	Cephalon, Inc.	Processes for the preparation of bendamustine
EP2367542B1 (en)	2008-12-03	2014-01-01	Astellas Deutschland GmbH	Oral dosage forms of bendamustine
CN101691359B (zh)	2009-09-30	2011-04-13	深圳万乐药业有限公司	一种高纯度的盐酸苯达莫司汀的合成方法
EP2516404A4 (en) *	2009-12-23	2013-04-17	Reddys Lab Ltd Dr	PREPARATION OF BENDAMUSTINE AND ITS SALTS
JO3659B1 (ar)	2010-06-02	2020-08-27	Astellas Deutschland Gmbh	أشكال جرعات بينداموستين عن طريق الفم وإستخداماته العلاجية
DE102010055499A1 (de) *	2010-12-22	2011-06-16	W.C. Heraeus Gmbh	Prozess zur Herstellung von Bendamustinalkylester, Bendarmustin sowie Derivaten davon

2012
- 2012-04-26 PT PT121657282T patent/PT2656843E/pt unknown
- 2012-04-26 ES ES12165728.2T patent/ES2535511T3/es active Active
- 2012-04-26 SI SI201230205T patent/SI2656843T1/sl unknown
- 2012-04-26 EP EP12165728.2A patent/EP2656843B1/en not_active Not-in-force
- 2012-04-26 DK DK12165728.2T patent/DK2656843T3/en active
- 2012-04-26 PL PL12165728T patent/PL2656843T3/pl unknown
2013
- 2013-04-25 US US13/870,759 patent/US8809549B2/en not_active Expired - Fee Related
2015
- 2015-04-21 HR HRP20150436TT patent/HRP20150436T1/hr unknown

Also Published As

Publication number	Publication date
US8809549B2 (en)	2014-08-19
EP2656843A1 (en)	2013-10-30
PL2656843T3 (pl)	2015-08-31
HRP20150436T1 (hr)	2015-05-22
DK2656843T3 (en)	2015-04-20
SI2656843T1 (sl)	2015-06-30
EP2656843B1 (en)	2015-03-18
US20130289032A1 (en)	2013-10-31
ES2535511T3 (es)	2015-05-12

Publication	Publication Date	Title
ZA202100373B (en)	2023-04-26	Therapeutically active compounds and their methods of use
GB201218307D0 (en)	2012-11-28	Patient monitor
GB2519257B (en)	2017-11-08	Magnetometer for medical use
EP2811897A4 (en)	2016-10-26	MEDICAL TERMINAL AND APPLICATION METHOD
SG10201609940RA (en)	2016-12-29	Compounds and their methods of use
GB201510816D0 (en)	2015-08-05	Medical tubes and methods of manufacture
ZA201405248B (en)	2017-04-26	Anesthetic compounds and related methods of use
ZA201405163B (en)	2018-05-30	Therapeutically active compounds and their methods of use
EP2804850A4 (en)	2015-09-23	THERAPEUTIC ACTIVE SUBSTANCES AND METHOD FOR THEIR USE
PL2848254T3 (pl)	2017-03-31	Pochodne pirazolu i ich zastosowanie w celach medycznych
EP2867209A4 (en)	2015-11-25	COMPOUNDS AND THEIR THERAPEUTIC USES
EP2867239A4 (en)	2015-12-23	OXABICYCLOHEPTANES AND OXABICYCLOHEPTENES FOR THE TREATMENT OF DIABETES
PL2656843T3 (pl)	2015-08-31	Estry bendamustyny i związki pokrewne i ich medyczne zastosowanie
GB201205189D0 (en)	2012-05-09	Novel medical use
GB201215502D0 (en)	2012-10-17	Medical use
ZA201408128B (en)	2015-12-23	Etract of greyia radlkoferi and use thereof
GB201216381D0 (en)	2012-10-31	New compounds and medical uses
GB201208970D0 (en)	2012-07-04	New compounds and medical uses
GB201104875D0 (en)	2011-05-04	New compounds and medical uses
GB201104872D0 (en)	2011-05-04	New compounds and medical uses
HUP1200530A2 (en)	2014-03-28	Medical splint
GB201208505D0 (en)	2012-06-27	Treatment of skin condition
GB201104632D0 (en)	2011-05-04	Use of medicament