PL2656843T3 - Estry bendamustyny i związki pokrewne i ich medyczne zastosowanie - Google Patents

Estry bendamustyny i związki pokrewne i ich medyczne zastosowanie

Info

Publication number: PL2656843T3
Authority: PL; Poland
Prior art keywords: bendamustine; esters; related compounds; medical use; medical
Prior art date: 2012-04-26

Application number

PL12165728T

Other languages

English (en)

Inventor

Helmut Schickaneder

Armin Buschauer

Günther Bernhardt

Christian Schickaneder

Michael Limmert

Stefan Huber

Original Assignee

Synbias Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-04-26

Filing date

2012-04-26

Publication date

2015-08-31

2012-04-26 Application filed by Synbias Pharma Ag filed Critical Synbias Pharma Ag

2015-08-31 Publication of PL2656843T3 publication Critical patent/PL2656843T3/pl

Links

YTKUWDBFDASYHO-UHFFFAOYSA-N bendamustine Chemical compound ClCCN(CCCl)C1=CC=C2N(C)C(CCCC(O)=O)=NC2=C1 YTKUWDBFDASYHO-UHFFFAOYSA-N 0.000 title 1
229960002707 bendamustine Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
150000002148 esters Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Materials For Medical Uses (AREA)
Hydrogenated Pyridines (AREA)

PL12165728T 2012-04-26 2012-04-26 Estry bendamustyny i związki pokrewne i ich medyczne zastosowanie PL2656843T3 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP12165728.2A EP2656843B1 (en)	2012-04-26	2012-04-26	Esters of bendamustine and related compounds, and medical use thereof

Publications (1)

Publication Number	Publication Date
PL2656843T3 true PL2656843T3 (pl)	2015-08-31

Family

ID=46045872

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL12165728T PL2656843T3 (pl)	2012-04-26	2012-04-26	Estry bendamustyny i związki pokrewne i ich medyczne zastosowanie

Country Status (8)

Country	Link
US (1)	US8809549B2 (pl)
EP (1)	EP2656843B1 (pl)
DK (1)	DK2656843T3 (pl)
ES (1)	ES2535511T3 (pl)
HR (1)	HRP20150436T1 (pl)
PL (1)	PL2656843T3 (pl)
PT (1)	PT2656843E (pl)
SI (1)	SI2656843T1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA117809C2 (uk)	2012-06-19	2018-10-10	Хельмут Шикканедер	Похідні бендамустину, споріднені сполуки та їхнє медичне застосування для лікування раку
EP2917183A1 (en) *	2012-11-12	2015-09-16	Ignyta, Inc.	Bendamustine derivatives and methods of using same
JP6359175B2 (ja)	2014-04-10	2018-07-18	フーベイバイオ−ファーマシューティカルインダストリアルテクノロジカルインスティテュートインコーポレイテッド	ＰＡＲＰ阻害剤としての４Ｈ‐ピラゾロ［１，５‐α］ベンゾイミダゾール化合物のアナログ
CN109153667B (zh) *	2016-02-24	2021-04-02	阿塞西翁制药公司	新型钾通道抑制剂
AU2018346395A1 (en)	2017-10-05	2020-04-30	Mecox Curemed Co., Ltd.	Oral bendamustine formulations

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR072777A1 (es)	2008-03-26	2010-09-22	Cephalon Inc	Formas solidas de clorhidrato de bendamustina
MX2011003751A (es) *	2008-10-08	2011-04-27	Cephalon Inc	Procesos para preparar bendamustina.
NZ592970A (en)	2008-12-03	2013-05-31	Astellas Deutschland Gmbh	Oral dosage forms of bendamustine
CN101691359B (zh)	2009-09-30	2011-04-13	深圳万乐药业有限公司	一种高纯度的盐酸苯达莫司汀的合成方法
US9376394B2 (en) *	2009-12-23	2016-06-28	Dr. Reddy's Laboratories Ltd.	Preparation of bendamustine and its salts
JO3659B1 (ar)	2010-06-02	2020-08-27	Astellas Deutschland Gmbh	أشكال جرعات بينداموستين عن طريق الفم وإستخداماته العلاجية
DE102010055499A1 (de) *	2010-12-22	2011-06-16	W.C. Heraeus Gmbh	Prozess zur Herstellung von Bendamustinalkylester, Bendarmustin sowie Derivaten davon

2012
- 2012-04-26 PT PT121657282T patent/PT2656843E/pt unknown
- 2012-04-26 PL PL12165728T patent/PL2656843T3/pl unknown
- 2012-04-26 DK DK12165728.2T patent/DK2656843T3/en active
- 2012-04-26 ES ES12165728.2T patent/ES2535511T3/es active Active
- 2012-04-26 SI SI201230205T patent/SI2656843T1/sl unknown
- 2012-04-26 EP EP12165728.2A patent/EP2656843B1/en not_active Not-in-force
2013
- 2013-04-25 US US13/870,759 patent/US8809549B2/en not_active Expired - Fee Related
2015
- 2015-04-21 HR HRP20150436TT patent/HRP20150436T1/hr unknown

Also Published As

Publication number	Publication date
EP2656843B1 (en)	2015-03-18
PT2656843E (pt)	2015-04-14
EP2656843A1 (en)	2013-10-30
US20130289032A1 (en)	2013-10-31
SI2656843T1 (sl)	2015-06-30
HRP20150436T1 (hr)	2015-05-22
ES2535511T3 (es)	2015-05-12
US8809549B2 (en)	2014-08-19
DK2656843T3 (en)	2015-04-20

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