PT2814965T - Proteínas pesticidas manipuladas - Google Patents

Proteínas pesticidas manipuladas

Info

Publication number
PT2814965T
PT2814965T PT137034906T PT13703490T PT2814965T PT 2814965 T PT2814965 T PT 2814965T PT 137034906 T PT137034906 T PT 137034906T PT 13703490 T PT13703490 T PT 13703490T PT 2814965 T PT2814965 T PT 2814965T
Authority
PT
Portugal
Prior art keywords
pesticides
manipulated
proteins
pesticides proteins
manipulated pesticides
Prior art date
Application number
PT137034906T
Other languages
English (en)
Inventor
Lee Mikyong
Shong Chen Jeng
Marie De Fontes Cheryl
Conville Jared
Palekar Narendra
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of PT2814965T publication Critical patent/PT2814965T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50Isolated enzymes; Isolated proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8285Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for nematode resistance
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146Genetically Modified [GMO] plants, e.g. transgenic plants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pest Control & Pesticides (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Agronomy & Crop Science (AREA)
  • Virology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
PT137034906T 2012-02-16 2013-01-23 Proteínas pesticidas manipuladas PT2814965T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261599583P 2012-02-16 2012-02-16

Publications (1)

Publication Number Publication Date
PT2814965T true PT2814965T (pt) 2018-05-23

Family

ID=47682062

Family Applications (1)

Application Number Title Priority Date Filing Date
PT137034906T PT2814965T (pt) 2012-02-16 2013-01-23 Proteínas pesticidas manipuladas

Country Status (16)

Country Link
US (2) US10023876B2 (pt)
EP (1) EP2814965B1 (pt)
CN (1) CN104145020B (pt)
AR (1) AR090070A1 (pt)
AU (2) AU2013219927B2 (pt)
BR (1) BR112014020164B1 (pt)
CA (1) CA2860626C (pt)
CL (1) CL2014002148A1 (pt)
EA (1) EA031448B1 (pt)
ES (1) ES2670505T3 (pt)
MX (1) MX356581B (pt)
PH (1) PH12014501854A1 (pt)
PT (1) PT2814965T (pt)
UA (1) UA116881C2 (pt)
WO (1) WO2013122720A2 (pt)
ZA (1) ZA201405056B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10329570B2 (en) * 2014-07-31 2019-06-25 Academia Sinica Antagonistic PD-1 aptamer and its applications in cancer therapy related applications
CN106794232B (zh) * 2014-08-29 2021-08-31 先正达参股股份有限公司 修饰的vip3多肽
MX394903B (es) 2016-09-09 2025-03-24 Syngenta Participations Ag Proteínas insecticidas.
EP3688013A4 (en) * 2017-09-26 2021-05-12 Dow Agrosciences LLC CHIMERIC INSECTICIDAL PROTEINS
KR102198072B1 (ko) * 2020-03-04 2021-01-04 씨제이제일제당 주식회사 글루타민 신테타아제 변이형 폴리펩티드 및 이를 이용한 l-글루타민 생산 방법
EP4271699A4 (en) * 2021-01-04 2025-10-22 The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo TOXINS AND ANTI-PEST CELLS
KR20240127466A (ko) * 2022-01-06 2024-08-22 디씨엠 스리람 리미티드 살곤충성 단백질 및 그의 용도
CN114907458B (zh) * 2022-05-10 2023-12-22 山东大学 一种活性提高的Vip3A突变蛋白及其应用
PE20251581A1 (es) * 2022-09-01 2025-06-16 Qingdao Kingagroot Seed Science Co Ltd Una proteina insecticida mutante vip3 y su aplicacion
AR134711A1 (es) 2023-12-18 2026-03-04 Syngenta Crop Protection Ag Formulación
CN120554468A (zh) * 2024-02-28 2025-08-29 青岛清原种子科学有限公司 Vip3Aa突变蛋白及其在控制害虫上的应用

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535060A (en) 1983-01-05 1985-08-13 Calgene, Inc. Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthetase, production and use
ATE100141T1 (de) 1984-03-06 1994-01-15 Mgi Pharma Inc Herbizide resistenz in pflanzen.
US4761373A (en) 1984-03-06 1988-08-02 Molecular Genetics, Inc. Herbicide resistance in plants
US5100792A (en) 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
US5036006A (en) 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US4940835A (en) 1985-10-29 1990-07-10 Monsanto Company Glyphosate-resistant plants
US4810648A (en) 1986-01-08 1989-03-07 Rhone Poulenc Agrochimie Haloarylnitrile degrading gene, its use, and cells containing the gene
DE3765449D1 (de) 1986-03-11 1990-11-15 Plant Genetic Systems Nv Durch gentechnologie erhaltene und gegen glutaminsynthetase-inhibitoren resistente pflanzenzellen.
US4975374A (en) 1986-03-18 1990-12-04 The General Hospital Corporation Expression of wild type and mutant glutamine synthetase in foreign hosts
NZ221259A (en) 1986-07-31 1990-05-28 Calgene Inc Seed specific transcriptional regulation
US5276268A (en) 1986-08-23 1994-01-04 Hoechst Aktiengesellschaft Phosphinothricin-resistance gene, and its use
US5273894A (en) 1986-08-23 1993-12-28 Hoechst Aktiengesellschaft Phosphinothricin-resistance gene, and its use
US5013659A (en) 1987-07-27 1991-05-07 E. I. Du Pont De Nemours And Company Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase
TR27832A (tr) 1987-04-29 1995-08-31 Monsanto Co Zararli ucucu hasarata mukavim bitkiler.
US6040504A (en) 1987-11-18 2000-03-21 Novartis Finance Corporation Cotton promoter
US5614395A (en) 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
FI891054L (fi) 1988-03-08 1989-09-09 Ciba Geigy Ag Kemiskt reglerbara dna-sekvenser och gener samt olika anvaendningar daerav.
ES2060765T3 (es) 1988-05-17 1994-12-01 Lubrizol Genetics Inc Sistema promotor de ubiquitina en plantas.
NZ230375A (en) 1988-09-09 1991-07-26 Lubrizol Genetics Inc Synthetic gene encoding b. thuringiensis insecticidal protein
US5162602A (en) 1988-11-10 1992-11-10 Regents Of The University Of Minnesota Corn plants tolerant to sethoxydim and haloxyfop herbicides
EP1103616A3 (en) 1989-02-24 2001-06-27 Monsanto Company Synthetic plant genes and method for preparation
EP0388186A1 (en) 1989-03-17 1990-09-19 E.I. Du Pont De Nemours And Company External regulation of gene expression
US5641876A (en) 1990-01-05 1997-06-24 Cornell Research Foundation, Inc. Rice actin gene and promoter
US5484956A (en) 1990-01-22 1996-01-16 Dekalb Genetics Corporation Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
ES2187497T3 (es) 1990-04-12 2003-06-16 Syngenta Participations Ag Promotores preferentemente en tejidos.
US5451513A (en) 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
US5459252A (en) 1991-01-31 1995-10-17 North Carolina State University Root specific gene promoter
US5767366A (en) 1991-02-19 1998-06-16 Louisiana State University Board Of Supervisors, A Governing Body Of Louisiana State University Agricultural And Mechanical College Mutant acetolactate synthase gene from Ararbidopsis thaliana for conferring imidazolinone resistance to crop plants
DE69230290T2 (de) 1991-08-27 2000-07-20 Novartis Ag, Basel Proteine mit insektiziden eigenschaften gegen homopteran insekten und ihre verwendung im pflanzenschutz
US5994629A (en) 1991-08-28 1999-11-30 Novartis Ag Positive selection
GB9304200D0 (en) 1993-03-02 1993-04-21 Sandoz Ltd Improvements in or relating to organic compounds
US5304730A (en) 1991-09-03 1994-04-19 Monsanto Company Virus resistant plants and method therefore
UA48104C2 (uk) 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
US5849870A (en) 1993-03-25 1998-12-15 Novartis Finance Corporation Pesticidal proteins and strains
US5877012A (en) 1993-03-25 1999-03-02 Novartis Finance Corporation Class of proteins for the control of plant pests
DE4317845A1 (de) 1993-05-28 1994-12-01 Bayer Ag Desoxyribonukleinsäuren
US5576198A (en) 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
US5545818A (en) 1994-03-11 1996-08-13 Calgene Inc. Expression of Bacillus thuringiensis cry proteins in plant plastids
US5545817A (en) 1994-03-11 1996-08-13 Calgene, Inc. Enhanced expression in a plant plastid
US5437992A (en) 1994-04-28 1995-08-01 Genencor International, Inc. Five thermostable xylanases from microtetraspora flexuosa for use in delignification and/or bleaching of pulp
US6808904B2 (en) 1994-06-16 2004-10-26 Syngenta Participations Ag Herbicide-tolerant protox genes produced by DNA shuffling
ES2289743T3 (es) 1994-12-30 2008-02-01 Seminis Vegetable Seeds, Inc. Plantas transgenicas expresando construcciones de adn comprendiendo una pluralidad de genes para impartir una resistencia viral.
GB9515941D0 (en) 1995-08-03 1995-10-04 Zeneca Ltd DNA constructs
US5853973A (en) 1995-04-20 1998-12-29 American Cyanamid Company Structure based designed herbicide resistant products
US6084155A (en) 1995-06-06 2000-07-04 Novartis Ag Herbicide-tolerant protoporphyrinogen oxidase ("protox") genes
GB9516241D0 (en) 1995-08-08 1995-10-11 Zeneca Ltd Dna constructs
GB9611777D0 (en) * 1996-06-06 1996-08-07 Ciba Geigy Ag Method of controlling insect pests
US5876739A (en) 1996-06-13 1999-03-02 Novartis Ag Insecticidal seed coating
US5849320A (en) 1996-06-13 1998-12-15 Novartis Corporation Insecticidal seed coating
CA2259142A1 (en) 1996-07-01 1998-01-08 Mycogen Corporation Bacillus thuringiensis toxins active against noctuidae pests
US6369213B1 (en) * 1996-07-01 2002-04-09 Mycogen Corporation Toxins active against pests
CA2267996A1 (en) 1996-10-30 1998-05-07 Mycogen Corporation Novel pesticidal toxins and nucleotide sequences which encode these toxins
US6242669B1 (en) 1996-10-30 2001-06-05 Mycogen Corporation Pesticidal toxins and nucleotide sequences which encode these toxins
US7129212B2 (en) 1996-10-30 2006-10-31 Mycogen Corporation Polynucleotides, pesticidal proteins, and novel methods of using them
US6603063B1 (en) 1999-05-07 2003-08-05 Mycogen Corp. Plants and cells transformed with a nucleic acid from Bacillus thuringiensis strain KB59A4-6 encoding a novel SUP toxin
US6121436A (en) 1996-12-13 2000-09-19 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
SE9700294L (sv) 1997-01-31 1998-02-16 Lennart Svensson Förankringsanordning samt förfarande vid montering av en sådan
BR9808483A (pt) 1997-04-03 2000-05-23 Novartis Ag Controle de peste de planta
DE69841438D1 (de) 1997-11-18 2010-02-25 Pioneer Hi Bred Int Mobilisierung eines viralen genoms aus t-dna durch ortsspezifische rekombinationssysteme
EP1032692A1 (en) 1997-11-18 2000-09-06 Pioneer Hi-Bred International, Inc. Targeted manipulation of herbicide-resistance genes in plants
WO1999025840A1 (en) 1997-11-18 1999-05-27 Pioneer Hi-Bred International, Inc. A novel method for the integration of foreign dna into eukaryoticgenomes
NZ503859A (en) 1997-11-18 2003-02-28 Pioneer Hi Bred Int Non-identical minimal recombination sites (FRT) which are non-identical for targeted integration of nucleotide sequences into transformed plants
MXPA02009335A (es) 2000-03-27 2003-02-12 Syngenta Participations Ag Promotores del virus de la rizadura amarilla del cestrum.
AR044724A1 (es) 2000-03-27 2005-10-05 Syngenta Participations Ag Promotores del virus de la rizadura amarilla del cestrum
AR035799A1 (es) 2001-03-30 2004-07-14 Syngenta Participations Ag Toxinas insecticidas aisladas de bacillus thuringiensis y sus usos.
DE10138285A1 (de) 2001-08-10 2003-03-06 Akzenta Paneele & Profile Gmbh Paneel sowie Befestigungssystem für Paneele
US7378493B2 (en) 2002-03-06 2008-05-27 Syngenta Participations Ag Vip3 toxins and methods of use
AU2003209748B2 (en) * 2002-03-22 2009-09-10 Bayer Cropscience Nv Novel bacillus thuringiensis insecticidal proteins
DE60332711D1 (de) 2002-03-22 2010-07-08 Bayer Bioscience Nv Neue insektizide proteine von bazillus thuringiensis
ATE495264T1 (de) 2003-10-06 2011-01-15 Syngenta Participations Ag In pflanzenplastiden funktionsfähiger promotor
WO2006083240A2 (en) 2003-12-19 2006-08-10 Syngenta Participations Ag Microbially expressed xylanases and their use as feed additives and other uses
EP2288708A1 (en) * 2008-05-01 2011-03-02 Bayer BioScience N.V. Armyworm insect resistance management in transgenic plants
WO2009149787A1 (en) * 2008-06-13 2009-12-17 Bayer Bioscience N.V. Bollworm insect resistance management in transgenic plants

Also Published As

Publication number Publication date
MX356581B (es) 2018-06-05
UA116881C2 (uk) 2018-05-25
EA201400924A1 (ru) 2015-07-30
PH12014501854B1 (en) 2014-11-17
AU2013219927A1 (en) 2014-08-07
BR112014020164A2 (pt) 2017-08-01
CN104145020B (zh) 2020-06-02
CL2014002148A1 (es) 2014-11-03
US20180291397A1 (en) 2018-10-11
US10023876B2 (en) 2018-07-17
AU2018253611B2 (en) 2021-04-01
CA2860626C (en) 2021-05-18
US20150020236A1 (en) 2015-01-15
ES2670505T3 (es) 2018-05-30
CN104145020A (zh) 2014-11-12
WO2013122720A3 (en) 2013-12-19
AR090070A1 (es) 2014-10-15
CA2860626A1 (en) 2013-08-22
AU2018253611A1 (en) 2018-11-22
EP2814965B1 (en) 2018-03-21
PH12014501854A1 (en) 2014-11-17
AU2013219927B2 (en) 2018-11-08
WO2013122720A2 (en) 2013-08-22
BR112014020164B1 (pt) 2022-09-13
EP2814965A2 (en) 2014-12-24
MX2014009282A (es) 2014-08-27
ZA201405056B (en) 2015-10-28
EA031448B1 (ru) 2019-01-31

Similar Documents

Publication Publication Date Title
CY2024011I2 (el) Αντισωματα anti-fcrn
NL301178I2 (nl) Pegcetacoplan
DK2934584T3 (da) Anti-gdf15-antistoffer
HRP20181646T1 (hr) Konjugati pirolobenzodiazepin - anti-psma protutijela
IL236261A0 (en) Complexes of cytomegalovirus proteins
DK2951203T3 (da) Heterodimere proteiner
DK2680500T3 (da) Programregistrering
EP2931204A4 (en) RECONFIGURABLE EXOSCELET
DK3117837T3 (da) Antistofformuleringer
EP2816886A4 (en) AUTOMATIC LAWNMOWER
EP2884134A4 (en) HEAT REGULATORS
BR112014025037A2 (pt) anticorpo ou um fragmento funcional do mesmo, nucleotídeo, vetor recombinante, célula, métodos para a produção de um anticorpo ou fragmento funcional, para detecção ou ensaio de fgfr2 humano iiib, para a identificação de um indivíduo receptor de uma composição farmacêutica, e, para identificar e para produzir uma substância, forma modificada, composição, e, reagente
FR2994521B1 (fr) Taille-haie
DK3041857T3 (da) Protein a-kromatografi
CL2014002180A1 (es) Peptidos antomicrobianos
DK3521315T3 (da) Anti-transglutaminase-2-antistoffer
DK2828292T3 (da) Jcv-neutraliserende antistoffer
DK2859099T3 (da) Svampe-beta-xylosidase-varianter
DK2935330T3 (da) Anti-notch3-antistoffer
BR112014028441A2 (pt) composição de proteína
KR101867593B9 (ko) 발광 소자
BR112014021674A2 (pt) arilpirrolidinas pesticidas
EP2912055A4 (en) SYNTHETIC ENV PROTEINS
DE102012100780A8 (de) Zugmittelhebevorrichtung
BR112014029129A2 (pt) manipulação de proteínas