PT2880053T - Mitigação de fibrose e danos de tecidos por anticorpo antiltbp4 - Google Patents

Mitigação de fibrose e danos de tecidos por anticorpo antiltbp4

Info

Publication number
PT2880053T
PT2880053T PT138352430T PT13835243T PT2880053T PT 2880053 T PT2880053 T PT 2880053T PT 138352430 T PT138352430 T PT 138352430T PT 13835243 T PT13835243 T PT 13835243T PT 2880053 T PT2880053 T PT 2880053T
Authority
PT
Portugal
Prior art keywords
ltbp4
growth factor
binding protein
tissue damage
transforming growth
Prior art date
Application number
PT138352430T
Other languages
English (en)
Original Assignee
Ikaika Therapeutics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ikaika Therapeutics Llc filed Critical Ikaika Therapeutics Llc
Publication of PT2880053T publication Critical patent/PT2880053T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT138352430T 2012-08-01 2013-08-01 Mitigação de fibrose e danos de tecidos por anticorpo antiltbp4 PT2880053T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261678564P 2012-08-01 2012-08-01

Publications (1)

Publication Number Publication Date
PT2880053T true PT2880053T (pt) 2020-05-22

Family

ID=50025687

Family Applications (1)

Application Number Title Priority Date Filing Date
PT138352430T PT2880053T (pt) 2012-08-01 2013-08-01 Mitigação de fibrose e danos de tecidos por anticorpo antiltbp4

Country Status (14)

Country Link
US (12) US9873739B2 (pt)
EP (3) EP2880053B8 (pt)
AU (6) AU2013313282B2 (pt)
CA (1) CA2880649C (pt)
CY (1) CY1123029T1 (pt)
DK (1) DK2880053T3 (pt)
ES (2) ES2791778T3 (pt)
HR (1) HRP20200818T1 (pt)
HU (1) HUE049217T2 (pt)
PL (1) PL2880053T3 (pt)
PT (1) PT2880053T (pt)
RS (1) RS60318B1 (pt)
SI (1) SI2880053T1 (pt)
WO (1) WO2014039189A1 (pt)

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US20170232276A1 (en) * 2014-09-30 2017-08-17 Primegen Biotech, Llc Treatment of fibrosis using deep tissue heating and stem cell therapy
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EA201792500A1 (ru) 2015-05-13 2018-04-30 Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания Aav-опосредованная экспрессия антител против гриппа и способы их использования
JOP20190200A1 (ar) 2017-02-28 2019-08-27 Univ Pennsylvania تركيبات نافعة في معالجة ضمور العضل النخاعي
UY37620A (es) 2017-02-28 2018-08-31 Univ Pennsylvania Vacunas contra la gripe mediadas por aav novedosas
PT3589730T (pt) 2017-02-28 2024-02-28 Univ Pennsylvania Vetor de vírus adenoassociado (aav) de clado f e suas utilizações
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
CA3108282A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
SG11202100928QA (en) 2018-08-02 2021-02-25 Dyne Therapeutics Inc Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
WO2020132647A1 (en) 2018-12-21 2020-06-25 Northwestern University Use of annexins in preventing and treating muscle membrane injury
WO2020139977A1 (en) 2018-12-26 2020-07-02 Northwestern University Use of glucocorticoid steroids in preventing and treating conditions of muscle wasting, aging and metabolic disorder
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
WO2024182358A1 (en) * 2023-02-27 2024-09-06 Dyne Therapeutics, Inc. Methods and compositions for inhibiting progression of intramuscular fibrosis

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Also Published As

Publication number Publication date
EP4678239A2 (en) 2026-01-14
HK1211307A1 (en) 2016-05-20
US20180134785A1 (en) 2018-05-17
WO2014039189A1 (en) 2014-03-13
CA2880649A1 (en) 2014-03-13
ES2791778T3 (es) 2020-11-05
AU2019222850A1 (en) 2019-09-19
EP2880053B1 (en) 2020-02-26
EP2880053B8 (en) 2020-04-15
PL2880053T3 (pl) 2021-01-11
AU2013313282B2 (en) 2018-02-01
US20190002557A1 (en) 2019-01-03
AU2021200783A1 (en) 2021-03-04
US20210238274A1 (en) 2021-08-05
US9873739B2 (en) 2018-01-23
EP4678239A3 (en) 2026-04-08
US20200123247A1 (en) 2020-04-23
US20240287171A1 (en) 2024-08-29
RS60318B1 (sr) 2020-07-31
SI2880053T1 (sl) 2020-08-31
AU2024204925A1 (en) 2024-08-08
US20140037637A1 (en) 2014-02-06
US20190256589A1 (en) 2019-08-22
EP3711771C0 (en) 2025-09-03
ES3047691T3 (en) 2025-12-04
US20220089717A1 (en) 2022-03-24
CY1123029T1 (el) 2021-10-29
HUE049217T2 (hu) 2020-09-28
DK2880053T3 (da) 2020-05-11
EP2880053A1 (en) 2015-06-10
EP2880053A4 (en) 2016-03-09
US20230235044A1 (en) 2023-07-27
HRP20200818T1 (hr) 2020-08-07
CA2880649C (en) 2023-03-14
US20250109197A1 (en) 2025-04-03
EP3711771A1 (en) 2020-09-23
AU2021200783B2 (en) 2022-10-06
US20250346664A1 (en) 2025-11-13
EP3711771B1 (en) 2025-09-03
AU2018200078A1 (en) 2018-01-25
AU2013313282A1 (en) 2015-02-26
US20200385457A1 (en) 2020-12-10
AU2022271391A1 (en) 2022-12-15

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