PT2948184T - Conjugados de anticorpo-fármaco de duocarmicina apresentando uma melhor atividade antitumoral in vivo. - Google Patents

Conjugados de anticorpo-fármaco de duocarmicina apresentando uma melhor atividade antitumoral in vivo.

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Publication number
PT2948184T
PT2948184T PT157011065T PT15701106T PT2948184T PT 2948184 T PT2948184 T PT 2948184T PT 157011065 T PT157011065 T PT 157011065T PT 15701106 T PT15701106 T PT 15701106T PT 2948184 T PT2948184 T PT 2948184T
Authority
PT
Portugal
Prior art keywords
antitumor activity
vivo antitumor
showing improved
duocarmycin
duocarmycin adcs
Prior art date
Application number
PT157011065T
Other languages
English (en)
Inventor
Johannes Goedings Peter
Franciscus Maria Verheijden Gijsbertus
DOKTER Willem
Henry Beusker Patrick
Original Assignee
Synthon Biopharmaceuticals Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthon Biopharmaceuticals Bv filed Critical Synthon Biopharmaceuticals Bv
Publication of PT2948184T publication Critical patent/PT2948184T/pt

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    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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PT157011065T 2014-01-10 2015-01-09 Conjugados de anticorpo-fármaco de duocarmicina apresentando uma melhor atividade antitumoral in vivo. PT2948184T (pt)

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