PT3056485T - Compostos moduladores do recetor de androgénio - Google Patents

Compostos moduladores do recetor de androgénio

Info

Publication number: PT3056485T
Authority: PT; Portugal
Prior art keywords: modulating compounds; androgen; receiver modulating; androgen receiver; compounds
Prior art date: 2009-10-27

Application number

PT161577168T

Other languages

English (en)

Inventor

Wohlfahrt Gerd

Törmäkangas Olli

Karjalainen Arja

Knuuttila Pia

Holm Patrik

Rasku Sirpa

Vesalainen Anniina

Salo Harri

Höglund Iisa

Original Assignee

Orion Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-10-27

Filing date

2010-10-27

Publication date

2018-07-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43383475&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3056485(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2010-10-27 Application filed by Orion Corp filed Critical Orion Corp

2018-07-31 Publication of PT3056485T publication Critical patent/PT3056485T/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Dentistry (AREA)
Wood Science & Technology (AREA)
Plant Pathology (AREA)
Environmental Sciences (AREA)
Pest Control & Pesticides (AREA)
Agronomy & Crop Science (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PT161577168T 2009-10-27 2010-10-27 Compostos moduladores do recetor de androgénio PT3056485T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US25515909P	2009-10-27	2009-10-27

Publications (1)

Publication Number	Publication Date
PT3056485T true PT3056485T (pt)	2018-07-31

Family

ID=43383475

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
PT161577168T PT3056485T (pt)	2009-10-27	2010-10-27	Compostos moduladores do recetor de androgénio
PT181637653T PT3369732T (pt)	2009-10-27	2010-10-27	Compostos moduladores do recetor de androgénio
PT211696158T PT3885340T (pt)	2009-10-27	2010-10-27	Compostos moduladores do recetor de androgénio
PT107819187T PT2493858E (pt)	2009-10-27	2010-10-27	Compostos moduladores do recetor de androgénio

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
PT181637653T PT3369732T (pt)	2009-10-27	2010-10-27	Compostos moduladores do recetor de androgénio
PT211696158T PT3885340T (pt)	2009-10-27	2010-10-27	Compostos moduladores do recetor de androgénio
PT107819187T PT2493858E (pt)	2009-10-27	2010-10-27	Compostos moduladores do recetor de androgénio

Country Status (37)

Country	Link
US (5)	US8975254B2 (pt)
EP (5)	EP2493858B1 (pt)
JP (1)	JP5763083B2 (pt)
KR (2)	KR101670299B1 (pt)
CN (2)	CN105061313B (pt)
AR (1)	AR078793A1 (pt)
AU (1)	AU2010311299C1 (pt)
BR (1)	BR112012008823B8 (pt)
CA (1)	CA2777896C (pt)
CL (1)	CL2012000772A1 (pt)
CO (1)	CO6531494A2 (pt)
CY (2)	CY2020010I2 (pt)
DK (4)	DK3885340T3 (pt)
EA (1)	EA021170B1 (pt)
ES (4)	ES2486263T3 (pt)
FI (1)	FI3885340T3 (pt)
GE (1)	GEP20166472B (pt)
HR (4)	HRP20241681T1 (pt)
HU (4)	HUE039390T2 (pt)
IL (2)	IL218586A (pt)
LT (4)	LT3056485T (pt)
LU (1)	LUC00154I2 (pt)
MX (1)	MX2012004867A (pt)
MY (1)	MY159924A (pt)
NL (1)	NL301041I2 (pt)
NO (1)	NO2020018I1 (pt)
NZ (1)	NZ598747A (pt)
PE (1)	PE20121058A1 (pt)
PH (1)	PH12012500782A1 (pt)
PL (4)	PL3369732T3 (pt)
PT (4)	PT3056485T (pt)
RS (4)	RS57592B1 (pt)
SI (4)	SI3369732T1 (pt)
SM (3)	SMT202100480T1 (pt)
UA (1)	UA109535C2 (pt)
WO (1)	WO2011051540A1 (pt)
ZA (1)	ZA201202655B (pt)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5996532B2 (ja) *	2010-07-15	2016-09-21	バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒＩｎｔｅｌｌｅｃｔｕａｌＰｒｏｐｅｒｔｙＧｍｂＨ	有害生物防除剤としての新規複素環式化合物
WO2012143599A1 (en) *	2011-04-21	2012-10-26	Orion Corporation	Androgen receptor modulating carboxamides
EP2574607A1 (en) *	2011-09-06	2013-04-03	F. Hoffmann-La Roche AG	PDE10 modulators
BR112014022700A2 (pt) *	2012-03-15	2020-06-30	Signal Pharmaceuticals, Llc	uso de uma quantidade eficaz de um inibidor da quinase tor, método para melhorar o critério do grupo de trabalho 2 do antígeno prostático específico (psawg2), método para a inibição da fosforilação de s6rp, 4e-bp1 e/ou de akt, método para a inibição da atividade da proteína quinase dependente do dna (dna-pk), método para a medição da inibição da fosforilação de s6rp, 4e-bp1 ou akt, método para a medição da inibição da fosforilação de dna-pk s2056 e kit
JPWO2013141362A1 (ja) *	2012-03-23	2015-08-03	日本農薬株式会社	チアゾールカルボキサミド誘導体及びその使用方法
HK1203197A1 (en)	2012-06-15	2015-10-23	Taisho Pharmaceutical Co., Ltd.	Branched chain alkyl heteroaromatic ring derivative
EA201590197A1 (ru)	2012-08-23	2015-07-30	Алиос Биофарма, Инк.	Соединения для лечения парамиксовирусных вирусных инфекций
CN102952095A (zh) *	2012-10-19	2013-03-06	盛世泰科生物医药技术(苏州)有限公司	一种2-羧酸乙酯-5-溴甲基噻唑的合成方法
AU2014308991B2 (en)	2013-08-21	2019-02-14	Janssen Biopharma, Inc.	Antiviral compounds
WO2015172196A1 (en) *	2014-05-13	2015-11-19	Monash University	Heterocyclic compounds and use of same
US12312316B2 (en)	2015-01-20	2025-05-27	Arvinas Operations, Inc.	Compounds and methods for the targeted degradation of androgen receptor
JP6817962B2 (ja)	2015-01-20	2021-01-20	アルビナス・オペレーションズ・インコーポレイテッドＡｒｖｉｎａｓＯｐｅｒａｔｉｏｎｓ，Ｉｎｃ．	ターゲティングされたアンドロゲン受容体分解のための化合物および方法
EP3250554B1 (en)	2015-01-30	2022-05-18	Orion Corporation	A carboxamide derivative and its diastereomers in stable crystalline form
MA41614A (fr) *	2015-02-25	2018-01-02	Alios Biopharma Inc	Composés antiviraux
HUE049144T2 (hu) *	2015-04-09	2020-08-28	Orion Corp	Eljárás anrdogén receptorantagonisták és azok intermedierjeinek elõállítására
JP2018515623A (ja) *	2015-05-18	2018-06-14	トランスレイショナル・ドラッグ・ディベロップメント・エルエルシー	キナーゼ阻害剤としての複素環式化合物
EP3388428B1 (en) *	2015-12-07	2021-08-04	Suzhou Sinovent Pharmaceuticals Company	Five-membered heterocyclic amides wnt pathway inhibitor
CN107286094A (zh) *	2016-04-12	2017-10-24	常州爱诺新睿医药技术有限公司	一种bay-1841788与药用辅料的固体分散体及其制备方法
JP6716023B2 (ja) *	2016-08-26	2020-07-01	クリスタルファーマシューティカル（スーチョウ）カンパニー，リミテッド	アンドロゲン受容体拮抗薬の結晶形及びその製造方法並びに用途
CN110506039A (zh) *	2016-10-11	2019-11-26	阿尔维纳斯股份有限公司	用于雄激素受体靶向降解的化合物和方法
CN121181479A (zh) *	2017-03-07	2025-12-23	奥赖恩公司	结晶药物产品的制备
WO2019002068A1 (en)	2017-06-28	2019-01-03	Bayer Consumer Care Ag	COMBINATION OF A PI3K INHIBITOR AND AN ANDROGEN RECEPTOR ANTAGONIST
CN110944979B (zh) *	2017-08-09	2023-05-12	杭州领业医药科技有限公司	Odm-201晶型及其制备方法和药物组合物
CN107602471B (zh) *	2017-09-22	2021-04-27	成都恒汇化成医药科技有限公司	一种达罗鲁胺的晶型制备方法
JP2021515040A (ja) *	2018-02-27	2021-06-17	サンド・アクチエンゲゼルシヤフト	ダロルタミドの結晶形態ｉｉ
EP3836933A4 (en) *	2018-08-13	2022-08-10	National Centre for Biological Sciences-TIFR	INHIBITORS AGAINST HIV-1-NEF-CD80/CD86 INTERACTIONS FOR THERAPEUTIC INTERVENTIONS
US20210386826A1 (en)	2018-11-05	2021-12-16	Pfizer Inc.	Combination for Treating Cancer
EP3917519A1 (en)	2019-01-30	2021-12-08	Aragon Pharmaceuticals, Inc.	Anti-androgens for the treatment of metastatic castration-sensitive prostate cancer
CN111620821B (zh) *	2019-02-27	2022-02-11	深圳市塔吉瑞生物医药有限公司	取代的吡唑类化合物及包含该化合物的组合物及其用途
WO2021001603A1 (en)	2019-07-02	2021-01-07	Orion Corporation	Pharmaceutical composition of darolutamide
CN110590668A (zh) *	2019-07-17	2019-12-20	江苏君若医药有限公司	N-[(1s)-2-[3-(3-氯-4-氰基苯基)-1h-吡唑-1-基]-1-甲基乙基]-5-(1-羟基乙基)- 1h-吡唑-3-甲酰胺的制备方法
TWI857119B (zh)	2019-08-08	2024-10-01	香港商來凱有限公司	治療癌症之方法
CN111116476A (zh) *	2019-12-27	2020-05-08	武汉九州钰民医药科技有限公司	制备抗肿瘤药物多拉米胺的方法
CR20220630A (es)	2020-05-09	2023-01-23	Arvinas Operations Inc	Métodos para fabricar un compuesto bifuncional, formas ultrapuras del compuesto bifuncional y formas de dosificación que comprenden el mismo
CN120192300A (zh)	2020-05-11	2025-06-24	奥赖恩公司	制备雄激素受体拮抗剂及其中间体的方法
AU2021325426A1 (en)	2020-08-13	2023-03-09	Astellas Pharma Inc.	Combination therapy
CN111978534B (zh) *	2020-09-07	2022-05-31	陕西师范大学	一种含苯并咪唑液晶基元的侧链型液晶离聚物及其制备方法
WO2022200982A1 (en)	2021-03-24	2022-09-29	Pfizer Inc.	Combination of talazoparib and an anti-androgen for the treatment of ddr gene mutated metastatic castration-sensitive prostate cancer
US20240208991A1 (en) *	2021-08-04	2024-06-27	Lg Chem, Ltd.	Novel compound and organic light emitting device comprising the same
CN113527208A (zh) *	2021-08-31	2021-10-22	江西金丰药业有限公司	一步法制备2-氯-4-（1h-吡唑-3-基）苯甲腈的方法
CN113861115A (zh) *	2021-09-10	2021-12-31	浙江师范大学	一种吡唑酰胺类衍生物及合成方法和应用
EP4486727B1 (en)	2022-02-28	2026-02-25	Química Sintética, S.A.	Crystalline form of darolutamide
JP7805983B2 (ja)	2022-03-22	2026-01-26	アッヴィ・インコーポレイテッド	ブルトン型チロシンキナーゼを分解するためのピリミジン
CN118973572A (zh)	2022-04-07	2024-11-15	阿斯利康(瑞典)有限公司	用于治疗癌症的组合疗法
TWI883565B (zh)	2022-10-02	2025-05-11	美商輝瑞大藥廠	用於治療轉移性去勢抵抗性前列腺癌之他拉唑帕尼及恩雜魯胺之組合
WO2024121163A1 (en)	2022-12-06	2024-06-13	Cancer Research Technology Limited	Combination of 10d1f and an androgen inhibitor for treatment and prevention of cancers
TW202425976A (zh)	2022-12-17	2024-07-01	美商輝瑞大藥廠	用於治療轉移性去勢抵抗性前列腺癌之他拉唑帕尼及恩雜魯胺之組合
TW202521513A (zh)	2023-08-17	2025-06-01	芬蘭商奧利安公司	雄性素受體拮抗劑及其中間物之製備方法
CN117776973A (zh) *	2023-09-20	2024-03-29	山东特珐曼药业有限公司	一种4-甲酰基-3-甲氧基苯甲腈的制备方法
TW202535392A (zh)	2023-12-08	2025-09-16	美商亞文納營運公司	使用雄性素受體降解劑治療脊髓延髓性肌肉萎縮
WO2025146444A1 (en)	2024-01-03	2025-07-10	Bayer Aktiengesellschaft	Darolutamide in combination with braf and mek inhibitors for melanoma treatment
WO2025229051A1 (en)	2024-05-03	2025-11-06	F. Hoffmann-La Roche Ag	Use of atr inhibitors in combination with antiandrogen agent
WO2026078619A1 (en)	2024-10-09	2026-04-16	Pfizer Inc.	Combination of talazoparib and enzalutamide in the treatment of metastatic castration-resistant prostate cancer
WO2026078615A1 (en)	2024-10-09	2026-04-16	Pfizer Inc.	Combination of talazoparib and enzalutamide in the treatment of metastatic castration-resistant prostate cancer
CN121226255A (zh) *	2025-09-25	2025-12-30	安徽益普克医药科技发展有限公司	一种达罗他胺衍生物及其制备方法与用途

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE28864T1 (de)	1982-07-23	1987-08-15	Ici Plc	Amide-derivate.
FR2656609B1 (fr)	1989-12-28	1992-03-27	Synthelabo	Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
CZ244394A3 (en)	1993-10-08	1995-06-14	Shell Int Research	Herbicidal 1,2,4-oxadiazolecarboxylic acids amides, esters or halides
FR2741342B1 (fr)	1995-11-22	1998-02-06	Roussel Uclaf	Nouvelles phenylimidazolidines fluorees ou hydroxylees, procede, intermediaires de preparation, application comme medicaments, nouvelle utilisation et compositions pharmaceutiques
CN1129581C (zh)	1998-09-22	2003-12-03	山之内制药株式会社	氰基苯基衍生物
JP2005508978A (ja)	2001-11-02	2005-04-07	ファイザー・プロダクツ・インク	Ｐｄｅ９阻害薬によるインスリン抵抗性症候群及び２型糖尿病の治療
AU2002367424A1 (en)	2001-12-28	2003-07-24	Takeda Chemical Industries, Ltd.	Androgen receptor antagonists
JP2005516964A (ja) *	2001-12-28	2005-06-09	バイエル・フアーマシユーチカルズ・コーポレーシヨン	５−ｈｔ２ｃレセプターと関連する疾患における使用のための１ｈ−ピラゾリル誘導体化合物
EP1465872A1 (en) *	2001-12-28	2004-10-13	Bayer Pharmaceuticals Corporation	4-sulfide/sulfoxide/sulfonyl-1h-pyrazolyl derivative compounds, for use in diseases associated with the 5-ht2c receptor
WO2003073999A2 (en)	2002-03-01	2003-09-12	Pintex Pharmaceuticals, Inc.	Pini-modulating compounds and methods of use thereof
AR040149A1 (es) *	2002-06-07	2005-03-16	Novartis Ag	Compuestos de aminoacetonitrilo, un proceso para su preparacion, composicion, y uso del compuesto
WO2004013130A1 (en) *	2002-08-02	2004-02-12	Argenta Discovery Limited	Substituted thienyl-hydroxamic acids as histone deacetylase inhibitors
DE10322108B4 (de)	2003-05-09	2008-12-11	Bayer Schering Pharma Aktiengesellschaft	Antiandrogene Pyrrolidine mit tumorhemmender Wirksamkeit
JP4664814B2 (ja)	2003-06-12	2011-04-06	中外製薬株式会社	イミダゾリジン誘導体
WO2005030705A1 (en)	2003-09-24	2005-04-07	Methylgene, Inc.	Inhibitors of histone deacetylase
US8470829B2 (en)	2004-09-09	2013-06-25	Chugai Seiyaku Kabushiki Kaisha	Imidazolidine derivative and use thereof
JP2008007405A (ja) *	2004-12-07	2008-01-17	Takeda Chem Ind Ltd	カルボキサミド誘導体
EP1710237A1 (en) *	2005-04-08	2006-10-11	Bayer CropScience S.A.	New heterocyclylethylbenzamide derivatives
NZ564223A (en)	2005-05-13	2011-03-31	Univ California	Diarylhydantoin compounds for treating hormone refractory prostate cancer
US7709516B2 (en)	2005-06-17	2010-05-04	Endorecherche, Inc.	Helix 12 directed non-steroidal antiandrogens
AR057656A1 (es) *	2005-07-01	2007-12-12	Ligand Pharm Inc	Compuestos moduladores de receptores de androgeno y metodods relacionados
GB0518237D0 (en)	2005-09-07	2005-10-19	Angeletti P Ist Richerche Bio	Therapeutic compounds
CA2669736C (en)	2005-11-03	2017-02-21	Chembridge Research Laboratories, Inc.	Heterocyclic compounds as tyrosine kinase modulators
TW200800997A (en)	2006-03-22	2008-01-01	Astrazeneca Ab	Chemical compounds
JP5205274B2 (ja) *	2006-11-22	2013-06-05	日本農薬株式会社	新規なピラゾール誘導体、有害生物防除剤及びその使用方法
WO2008124000A2 (en)	2007-04-02	2008-10-16	Ligand Pharmaceuticals Incorporated	Thiazole derivatives as androgen receptor modulator compounds
US7968536B2 (en) *	2007-06-29	2011-06-28	Millennium Pharmaceuticals, Inc.	Heterocyclic compounds useful as RAF kinase inhibitors
JPWO2009028543A1 (ja)	2007-08-30	2010-12-02	武田薬品工業株式会社	置換ピラゾール誘導体
EP2620432A3 (en)	2007-10-26	2013-12-18	The Regents Of the University of California	Diarylhydantoin compounds
PE20091653A1 (es)	2008-03-26	2009-11-14	Takeda Pharmaceutical	Derivados sustituidos de pirazol y su uso
CA2725481A1 (en)	2008-06-18	2009-12-23	Pfizer Limited	Nicotinamide derivatives

2010
- 2010-10-26 AR ARP100103942A patent/AR078793A1/es active IP Right Grant
- 2010-10-27 SI SI201032078T patent/SI3369732T1/sl unknown
- 2010-10-27 PT PT161577168T patent/PT3056485T/pt unknown
- 2010-10-27 CN CN201510501603.4A patent/CN105061313B/zh active Active
- 2010-10-27 EP EP10781918.7A patent/EP2493858B1/en active Active
- 2010-10-27 KR KR1020167023703A patent/KR101670299B1/ko active Active
- 2010-10-27 GE GEAP201012722A patent/GEP20166472B/en unknown
- 2010-10-27 WO PCT/FI2010/000065 patent/WO2011051540A1/en not_active Ceased
- 2010-10-27 PT PT181637653T patent/PT3369732T/pt unknown
- 2010-10-27 EP EP16157716.8A patent/EP3056485B1/en active Active
- 2010-10-27 HU HUE16157716A patent/HUE039390T2/hu unknown
- 2010-10-27 AU AU2010311299A patent/AU2010311299C1/en active Active
- 2010-10-27 EP EP14162075.7A patent/EP2754656A1/en not_active Withdrawn
- 2010-10-27 EA EA201270597A patent/EA021170B1/ru active Protection Beyond IP Right Term
- 2010-10-27 CA CA2777896A patent/CA2777896C/en active Active
- 2010-10-27 UA UAA201206302A patent/UA109535C2/ru unknown
- 2010-10-27 FI FIEP21169615.8T patent/FI3885340T3/fi active
- 2010-10-27 CN CN201080048340.1A patent/CN102596910B/zh active Active
- 2010-10-27 JP JP2012535889A patent/JP5763083B2/ja active Active
- 2010-10-27 SM SM20210480T patent/SMT202100480T1/it unknown
- 2010-10-27 PL PL18163765T patent/PL3369732T3/pl unknown
- 2010-10-27 PL PL16157716T patent/PL3056485T3/pl unknown
- 2010-10-27 ES ES10781918.7T patent/ES2486263T3/es active Active
- 2010-10-27 LT LTEP16157716.8T patent/LT3056485T/lt unknown
- 2010-10-27 ES ES16157716.8T patent/ES2678073T3/es active Active
- 2010-10-27 PT PT211696158T patent/PT3885340T/pt unknown
- 2010-10-27 DK DK21169615.8T patent/DK3885340T3/da active
- 2010-10-27 RS RS20180913A patent/RS57592B1/sr unknown
- 2010-10-27 SI SI201032153T patent/SI3885340T1/sl unknown
- 2010-10-27 RS RS20241370A patent/RS66289B1/sr unknown
- 2010-10-27 DK DK10781918.7T patent/DK2493858T3/da active
- 2010-10-27 RS RS20140420A patent/RS53469B/sr unknown
- 2010-10-27 MX MX2012004867A patent/MX2012004867A/es active IP Right Grant
- 2010-10-27 HU HUE21169615A patent/HUE069657T2/hu unknown
- 2010-10-27 DK DK18163765.3T patent/DK3369732T3/da active
- 2010-10-27 SM SM20240534T patent/SMT202400534T1/it unknown
- 2010-10-27 PL PL21169615.8T patent/PL3885340T3/pl unknown
- 2010-10-27 PH PH1/2012/500782A patent/PH12012500782A1/en unknown
- 2010-10-27 MY MYPI2012001441A patent/MY159924A/en unknown
- 2010-10-27 KR KR1020127013214A patent/KR101654529B1/ko active Active
- 2010-10-27 ES ES21169615T patent/ES2997997T3/es active Active
- 2010-10-27 DK DK16157716.8T patent/DK3056485T3/en active
- 2010-10-27 LT LTEP18163765.3T patent/LT3369732T/lt unknown
- 2010-10-27 LT LTEP21169615.8T patent/LT3885340T/lt unknown
- 2010-10-27 SI SI201030739T patent/SI2493858T1/sl unknown
- 2010-10-27 HR HRP20241681TT patent/HRP20241681T1/hr unknown
- 2010-10-27 PE PE2012000424A patent/PE20121058A1/es active IP Right Grant
- 2010-10-27 PT PT107819187T patent/PT2493858E/pt unknown
- 2010-10-27 PL PL10781918T patent/PL2493858T3/pl unknown
- 2010-10-27 EP EP18163765.3A patent/EP3369732B1/en active Active
- 2010-10-27 SI SI201031718T patent/SI3056485T1/en unknown
- 2010-10-27 BR BR112012008823A patent/BR112012008823B8/pt active IP Right Grant
- 2010-10-27 RS RS20210903A patent/RS62123B1/sr unknown
- 2010-10-27 HR HRP20140919AT patent/HRP20140919T1/hr unknown
- 2010-10-27 NZ NZ598747A patent/NZ598747A/xx unknown
- 2010-10-27 US US13/504,511 patent/US8975254B2/en active Active
- 2010-10-27 HU HUE18163765A patent/HUE055528T2/hu unknown
- 2010-10-27 EP EP21169615.8A patent/EP3885340B1/en active Active
- 2010-10-27 ES ES18163765T patent/ES2877248T3/es active Active
2012
- 2012-03-12 IL IL218586A patent/IL218586A/en active IP Right Grant
- 2012-03-28 CL CL2012000772A patent/CL2012000772A1/es unknown
- 2012-04-12 ZA ZA2012/02655A patent/ZA201202655B/en unknown
- 2012-04-27 CO CO12069611A patent/CO6531494A2/es active IP Right Grant
2014
- 2014-09-23 SM SM201400138T patent/SMT201400138B/xx unknown
2015
- 2015-01-16 US US14/598,973 patent/US9657003B2/en active Active
- 2015-03-30 IL IL238044A patent/IL238044A/en active IP Right Grant
2017
- 2017-04-13 US US15/486,995 patent/US10118933B2/en active Active
2018
- 2018-07-31 HR HRP20181229TT patent/HRP20181229T1/hr unknown
- 2018-09-25 US US16/140,716 patent/US10711013B2/en active Active
2020
- 2020-02-24 US US16/799,270 patent/US11046713B2/en active Active
- 2020-05-11 NL NL301041C patent/NL301041I2/nl unknown
- 2020-05-19 LU LU00154C patent/LUC00154I2/fr unknown
- 2020-05-26 HU HUS2000012C patent/HUS2000012I1/hu unknown
- 2020-06-05 CY CY2020010C patent/CY2020010I2/el unknown
- 2020-06-17 NO NO2020018C patent/NO2020018I1/no unknown
- 2020-06-26 LT LTPA2020514C patent/LTC2493858I2/lt unknown
2021
- 2021-07-22 HR HRP20211180TT patent/HRP20211180T1/hr unknown
- 2021-08-10 CY CY20211100717T patent/CY1124429T1/el unknown

Also Published As

Publication number	Publication date
US20170260206A1 (en)	2017-09-14
NO2020018I1 (no)	2020-06-17
BR112012008823B1 (pt)	2021-01-12
DK3885340T3 (da)	2025-01-06
KR101670299B1 (ko)	2016-10-28
EP2493858A1 (en)	2012-09-05
RS53469B (sr)	2014-12-31
CA2777896C (en)	2017-05-23
CY2020010I1 (el)	2020-11-25
AU2010311299A1 (en)	2012-04-12
HUS2000012I1 (hu)	2020-07-28
US20190100536A1 (en)	2019-04-04
WO2011051540A8 (en)	2012-05-24
AU2010311299A8 (en)	2012-06-14
ES2997997T3 (en)	2025-02-18
US10118933B2 (en)	2018-11-06
SMT202100480T1 (it)	2021-09-14
EA021170B1 (ru)	2015-04-30
DK3056485T3 (en)	2018-07-30
EP3369732B1 (en)	2021-05-26
PL3885340T3 (pl)	2025-03-24
MY159924A (en)	2017-02-15
EP2493858B1 (en)	2014-07-02
EP3056485B1 (en)	2018-05-09
DK3369732T3 (da)	2021-07-26
CN102596910B (zh)	2015-11-25
LT3369732T (lt)	2021-06-25
CN102596910A (zh)	2012-07-18
MX2012004867A (es)	2012-06-08
PE20121058A1 (es)	2012-08-18
NZ598747A (en)	2013-06-28
GEP20166472B (en)	2016-05-10
HRP20181229T1 (hr)	2018-10-05
PL2493858T3 (pl)	2015-01-30
SI2493858T1 (sl)	2014-10-30
HUE069657T2 (hu)	2025-04-28
CN105061313B (zh)	2017-07-18
US10711013B2 (en)	2020-07-14
LUC00154I2 (pt)	2021-02-17
BR112012008823A2 (pt)	2019-02-19
ES2486263T3 (es)	2014-08-18
AU2010311299B2 (en)	2014-07-17
CY2020010I2 (el)	2020-11-25
IL218586A0 (en)	2012-05-31
RS62123B1 (sr)	2021-08-31
SI3056485T1 (en)	2018-08-31
CN105061313A (zh)	2015-11-18
IL218586A (en)	2015-10-29
WO2011051540A1 (en)	2011-05-05
PT3369732T (pt)	2021-07-06
KR20120102057A (ko)	2012-09-17
US20200299307A1 (en)	2020-09-24
AR078793A1 (es)	2011-12-07
PL3056485T3 (pl)	2018-12-31
LT3885340T (lt)	2024-12-27
US9657003B2 (en)	2017-05-23
ES2678073T3 (es)	2018-08-08
HUE055528T2 (hu)	2021-12-28
UA109535C2 (uk)	2015-09-10
LT3056485T (lt)	2018-07-25
EP3885340B1 (en)	2024-11-27
EP3369732A1 (en)	2018-09-05
RS66289B1 (sr)	2025-01-31
JP5763083B2 (ja)	2015-08-12
HRP20211180T1 (hr)	2021-10-15
US8975254B2 (en)	2015-03-10
JP2013508447A (ja)	2013-03-07
SMT202400534T1 (it)	2025-01-14
PT2493858E (pt)	2014-09-03
WO2011051540A9 (en)	2012-06-21
EP3056485A1 (en)	2016-08-17
LUC00154I1 (pt)	2020-05-19
EA201270597A1 (ru)	2012-10-30
FI3885340T3 (fi)	2025-02-03
HUE039390T2 (hu)	2018-12-28
KR101654529B1 (ko)	2016-09-06
US20120225867A1 (en)	2012-09-06
LTPA2020514I1 (lt)	2020-07-27
ES2877248T3 (es)	2021-11-16
AU2010311299C1 (en)	2023-02-02
CY1124429T1 (el)	2022-07-22
US11046713B2 (en)	2021-06-29
LTC2493858I2 (lt)	2022-03-25
KR20160105927A (ko)	2016-09-07
NL301041I2 (nl)	2020-09-14
CL2012000772A1 (es)	2012-08-24
RS57592B1 (sr)	2018-11-30
CO6531494A2 (es)	2012-09-28
HK1173442A1 (zh)	2013-05-16
SI3369732T1 (sl)	2021-08-31
HRP20140919T1 (hr)	2014-11-21
EP3885340A1 (en)	2021-09-29
CA2777896A1 (en)	2011-05-05
EP2754656A1 (en)	2014-07-16
SI3885340T1 (sl)	2025-02-28
US20150203479A1 (en)	2015-07-23
HRP20241681T1 (hr)	2025-02-28
IL238044A (en)	2016-07-31
PT3885340T (pt)	2024-12-16
PL3369732T3 (pl)	2021-12-06
SMT201400138B (it)	2014-11-10
BR112012008823B8 (pt)	2021-05-25
DK2493858T3 (da)	2014-09-08
ZA201202655B (en)	2012-12-27
PH12012500782A1 (en)	2016-05-27

Publication	Publication Date	Title
PT3056485T (pt)	2018-07-31	Compostos moduladores do recetor de androgénio
BRPI1013614A2 (pt)	2019-09-24	compostos substituídos de espiro-amida
BRPI1005525A2 (pt)	2016-02-23	compostos de azaazuleno
BR112012012552A2 (pt)	2018-09-18	conjunto de bobinas receptoras
EP2438649A4 (en)	2015-01-28	COMMUNICATION IN CLOSE FIELDS
BR112012006859A2 (pt)	2019-09-24	compostos
PT2626350E (pt)	2015-08-03	Composto de ciclopropano
EP2456197A4 (en)	2013-07-17	RECEIVER
FI20095468A0 (fi)	2009-04-27	Antenniyhdistelmä
BR112012004821A2 (pt)	2017-05-30	unidade de rádio remota
ZA201205726B (en)	2013-09-25	Substituted naphthalenyl-pyrimidine compounds
BR112013007056A2 (pt)	2019-09-24	compostos de imina
EP2525500A4 (en)	2013-11-06	RECEIVER
BRPI1008616A2 (pt)	2016-03-15	aparelho de recepção
BRPI1009199A2 (pt)	2016-03-08	compostos de pirazinoisoquinolina
EP2400750A4 (en)	2012-08-22	TELEVISION RECEIVER
FR2951218B1 (fr)	2012-03-09	Pylone de communication
BRPI1014080A2 (pt)	2015-08-25	Compostos substituidos de enaminocarbolina
GB201013351D0 (en)	2010-09-22	Make over me app
TH94611B (th)	2009-03-27	เครื่องรับโทรทัศน์